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The map label for this gene is xseA

Identifier: 83590358

GI number: 83590358

Start: 1560632

End: 1561840

Strand: Reverse

Name: xseA

Synonym: Moth_1515

Alternate gene names: 83590358

Gene position: 1561840-1560632 (Counterclockwise)

Preceding gene: 83590359

Following gene: 83590357

Centisome position: 59.41

GC content: 67.0

Gene sequence:

>1209_bases
GTGCCGGAGGTTAAAGTCCTGGCGGTGAGGGAACTCACCGCCTATTTGCAGCGCCTCCTGGCCAACGACGGCCGCCTGGC
CAATGTCTGGGTAAAGGGCGAGATCTCCAACCTGCGCTCTCCAACCTCGGGCCATCTCTATTTCAGTCTCAAGGACCAGG
CTGCGACCCTGCGCTGCGTGATGTTTCAGGGCCGTAGCCGGGGCCTATCCCTGGGCCTGCGCGACGGCCTGGAGGTAATC
GCCAGGGGTCAGGTGGCCATTTACCCCCGGGACGGCGTCTACCAGCTCTATGTAGCCGAAATCTTCCCGGCAGGGACCGG
CCTGGCCAGCCTGGCCCTCCAGGAGTTGACCGCCCGCCTGGAACGGGAGGGTCTCTTTGCCGCCGACCGCAAGCGGCCCC
TGCCCCTGTTGCCACGCCGGGTGGGCCTGGTGACCTCCCCAACCGGGGCCGCCCTACGGGATATGATAACCATCAGCCGG
CGCCGCTTCCCCGGGATTGAACTGATCCTGGCGCCGGCCAGGGTCCAGGGGGAGGTGGCGCCCCGCCAGCTGGCCCTGGC
CCTGGAACTTCTGGCAAAAAGGGGAGGCGTTGATGTCATTATTATCGGCCGCGGTGGCGGCTCGGCCGAAGATTTAAGCG
CCTTCAACACCGAACTGGTGGCCAGGGCCATCTATGCCTGTCCGGTACCCGTCATTGCTGCCGTAGGCCATGAGACGGAT
CTCACCCTGGCCGACAGGGTAGCCGACCGGCGGGCGCCTACTCCTTCGGCGGCGGCGGAAATGGCCGTACCGGTGCGGGC
AGAACTGGAACAGCGCCTGAAGAGCCTGGCGGAGCGGGCCCGCCGCGGTATGGAACACCGCCTGGAGTTAGCCCGGGCTC
GGCTGGAGCGCCTGACCAAAAGCAGCGGCCTGGATCGGCCCCGCCAGGAGCTATATTACCGCCAGCAGTACGTGGATGGC
CTGGAACAGCGCCTGCTGGCCTCCTGGGAGCGTCGTTCCCGGGAGCGGGAGCAGGGTCTTAATCTCCTGGCTGCCCGCCT
GGAAGCCGCCAGCCCCCTGGCCATCCTGGCGCGTGGCTACGCCGTTTGCCGCCGTCCCGGCGACGGAGCGCCCCTGAAAT
CCAGCCGGGAAGTGCTCCCCGGGGAGAAGGTGGAGGTCATCCTGAAGGAAGGCCTTCTCCGGTGCCAGGTCGAAGAAGTC
GGCGGATAG

Upstream 100 bases:

>100_bases
CGGCCCAGAAGGCCGGTTGGATCACTCCCGTACCCGGCGGGGTAGGTCCCATGACCATTGCCATGCTCTTGAAGAATACA
GTCGAGGCGGCCCGGCGCTA

Downstream 100 bases:

>100_bases
GATGCAACTTACAAACCAAGCCACAATTTCACGGAGGAGCCCCACATGGGAGCCGACGCCTCCGCCATGAACAATGAAAA
TGTAAGCGATAGGGGCTGGG

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MPEVKVLAVRELTAYLQRLLANDGRLANVWVKGEISNLRSPTSGHLYFSLKDQAATLRCVMFQGRSRGLSLGLRDGLEVI
ARGQVAIYPRDGVYQLYVAEIFPAGTGLASLALQELTARLEREGLFAADRKRPLPLLPRRVGLVTSPTGAALRDMITISR
RRFPGIELILAPARVQGEVAPRQLALALELLAKRGGVDVIIIGRGGGSAEDLSAFNTELVARAIYACPVPVIAAVGHETD
LTLADRVADRRAPTPSAAAEMAVPVRAELEQRLKSLAERARRGMEHRLELARARLERLTKSSGLDRPRQELYYRQQYVDG
LEQRLLASWERRSREREQGLNLLAARLEAASPLAILARGYAVCRRPGDGAPLKSSREVLPGEKVEVILKEGLLRCQVEEV
GG

Sequences:

>Translated_402_residues
MPEVKVLAVRELTAYLQRLLANDGRLANVWVKGEISNLRSPTSGHLYFSLKDQAATLRCVMFQGRSRGLSLGLRDGLEVI
ARGQVAIYPRDGVYQLYVAEIFPAGTGLASLALQELTARLEREGLFAADRKRPLPLLPRRVGLVTSPTGAALRDMITISR
RRFPGIELILAPARVQGEVAPRQLALALELLAKRGGVDVIIIGRGGGSAEDLSAFNTELVARAIYACPVPVIAAVGHETD
LTLADRVADRRAPTPSAAAEMAVPVRAELEQRLKSLAERARRGMEHRLELARARLERLTKSSGLDRPRQELYYRQQYVDG
LEQRLLASWERRSREREQGLNLLAARLEAASPLAILARGYAVCRRPGDGAPLKSSREVLPGEKVEVILKEGLLRCQVEEV
GG
>Mature_401_residues
PEVKVLAVRELTAYLQRLLANDGRLANVWVKGEISNLRSPTSGHLYFSLKDQAATLRCVMFQGRSRGLSLGLRDGLEVIA
RGQVAIYPRDGVYQLYVAEIFPAGTGLASLALQELTARLEREGLFAADRKRPLPLLPRRVGLVTSPTGAALRDMITISRR
RFPGIELILAPARVQGEVAPRQLALALELLAKRGGVDVIIIGRGGGSAEDLSAFNTELVARAIYACPVPVIAAVGHETDL
TLADRVADRRAPTPSAAAEMAVPVRAELEQRLKSLAERARRGMEHRLELARARLERLTKSSGLDRPRQELYYRQQYVDGL
EQRLLASWERRSREREQGLNLLAARLEAASPLAILARGYAVCRRPGDGAPLKSSREVLPGEKVEVILKEGLLRCQVEEVG
G

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family

Homologues:

Organism=Escherichia coli, GI1788856, Length=441, Percent_Identity=39.0022675736961, Blast_Score=276, Evalue=1e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): EX7L_MOOTA (Q2RIB5)

Other databases:

- EMBL:   CP000232
- RefSeq:   YP_430367.1
- STRING:   Q2RIB5
- GeneID:   3831980
- GenomeReviews:   CP000232_GR
- KEGG:   mta:Moth_1515
- NMPDR:   fig|264732.9.peg.1520
- eggNOG:   COG1570
- HOGENOM:   HBG634411
- OMA:   SAVGHER
- PhylomeDB:   Q2RIB5
- BioCyc:   MTHE264732:MOTH_1515-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00378
- InterPro:   IPR013785
- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365
- Gene3D:   G3DSA:3.20.20.70
- TIGRFAMs:   TIGR00237

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti

EC number: =3.1.11.6

Molecular weight: Translated: 44119; Mature: 43988

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEVKVLAVRELTAYLQRLLANDGRLANVWVKGEISNLRSPTSGHLYFSLKDQAATLRCV
CCCCEEHHHHHHHHHHHHHHCCCCCEEEEEEEEEHHHCCCCCCCEEEEEECCCCCEEEEE
MFQGRSRGLSLGLRDGLEVIARGQVAIYPRDGVYQLYVAEIFPAGTGLASLALQELTARL
EECCCCCCCCCCHHHHHHHHCCCCEEEEECCCCEEEEHHHHCCCCCCHHHHHHHHHHHHH
EREGLFAADRKRPLPLLPRRVGLVTSPTGAALRDMITISRRRFPGIELILAPARVQGEVA
HHCCCCCCCCCCCCCCCCHHCCEEECCCHHHHHHHHHHHHHCCCCEEEEEECCHHCCCCC
PRQLALALELLAKRGGVDVIIIGRGGGSAEDLSAFNTELVARAIYACPVPVIAAVGHETD
HHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCC
LTLADRVADRRAPTPSAAAEMAVPVRAELEQRLKSLAERARRGMEHRLELARARLERLTK
CHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSGLDRPRQELYYRQQYVDGLEQRLLASWERRSREREQGLNLLAARLEAASPLAILARGY
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
AVCRRPGDGAPLKSSREVLPGEKVEVILKEGLLRCQVEEVGG
HHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHEEEHHHCCC
>Mature Secondary Structure 
PEVKVLAVRELTAYLQRLLANDGRLANVWVKGEISNLRSPTSGHLYFSLKDQAATLRCV
CCCEEHHHHHHHHHHHHHHCCCCCEEEEEEEEEHHHCCCCCCCEEEEEECCCCCEEEEE
MFQGRSRGLSLGLRDGLEVIARGQVAIYPRDGVYQLYVAEIFPAGTGLASLALQELTARL
EECCCCCCCCCCHHHHHHHHCCCCEEEEECCCCEEEEHHHHCCCCCCHHHHHHHHHHHHH
EREGLFAADRKRPLPLLPRRVGLVTSPTGAALRDMITISRRRFPGIELILAPARVQGEVA
HHCCCCCCCCCCCCCCCCHHCCEEECCCHHHHHHHHHHHHHCCCCEEEEEECCHHCCCCC
PRQLALALELLAKRGGVDVIIIGRGGGSAEDLSAFNTELVARAIYACPVPVIAAVGHETD
HHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCC
LTLADRVADRRAPTPSAAAEMAVPVRAELEQRLKSLAERARRGMEHRLELARARLERLTK
CHHHHHHHHCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SSGLDRPRQELYYRQQYVDGLEQRLLASWERRSREREQGLNLLAARLEAASPLAILARGY
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
AVCRRPGDGAPLKSSREVLPGEKVEVILKEGLLRCQVEEVGG
HHHCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHEEEHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA