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The map label for this gene is ppnK

Identifier: 83590352

GI number: 83590352

Start: 1553997

End: 1554932

Strand: Reverse

Name: ppnK

Synonym: Moth_1509

Alternate gene names: 83590352

Gene position: 1554932-1553997 (Counterclockwise)

Preceding gene: 83590353

Following gene: 83590351

Centisome position: 59.15

GC content: 59.83

Gene sequence:

>936_bases
TTGCAGCGGATAGGTATGGTGGCCAACCTGGAAAAACCCCGGGTACGAGAAACGGCCCTGGATATCATAAACTACCTGGA
GAGCAGGAACGTCCGGGTGCTGATCTCCACCAGGAAGGCTGCTGCCCTGGGGTGCCCCGAAAAGGGTGTAGCGGAAGAAG
AAGTAATTGCCGCCGAGGGACTTTTAGCCCTGGGGGGCGATGGCACCCTCCTGCGGGCGGCGCGGCTGGTGGCCCCGGCC
GGGACGCCGATCCTGGGGATCAACCTGGGGCACCTGGGCTTCCTGACGGAGATAGAGCTGACGGAGCTCTACCCGGCCCT
CGACAAACTCCTGGCCGGCGCCTACCGCATCGAAGAGCGCATGATGCTCCGGGGAACGGTCCAGAGGCCGGAAAAGGCAT
TAACCTGCACCGCTTTAAACGACATTGTCGTGACCAAGGGTGCTTTTTCCCGGATGCTCCGCCTGGAGGTTTATATTGAT
ACAGCCTATCTGGATACATACCCGGCCGACGGACTGATTGTCTCCTCCCCCACCGGCTCGACGGCTTACTCCCTGTCGGC
CGGTGGTCCCCTGGTTTCACCCCAGCTCCAGGTAATGATCCTGACCCCCATCTGTCCCCATACCCTTTATACCCGACCCC
TGGTGGTACCGGGGGAACAGGAGATCAGGGTCTGTGTCCATGCGCCCGGGGCCGAAGTTATGCTGACTGTCGACGGCCAG
CAAGGTTTGCACCTCCGTGACGGTGACGTCATCAGGGTAACCAGGGCCAGAACCCCGGCCCGTTTAATCAGGCTGCAAGA
TAACACCTTTTATAGCCTGGTACGGGAGAAACTGAAGGAAGGGGGGAGCCGGCAGGATGATGAAAACCCAGCGGCAACAG
TTAATCCTGAAACTGATAGCAAGTACCCCCATAGCCACCCAGGATCAACTGGCTAG

Upstream 100 bases:

>100_bases
AGCCTCATCAACCGGGTAGTTGCTGCGGCCCACGAGGGACTGTTGAAGCCGTAGTTTCATAGCGGGGGAGATAACCCCGC
CGGGGAAATGAGGGATTGCA

Downstream 100 bases:

>100_bases
AGAGTTGCGAAGGCGCGGTCTCAGGGTGACCCAGGCTACTGTCTCCCGGGATATCAAAGAACTGGGTCTGATCAAGGTAC
CGGCGGGGGAAAACCTCTAC

Product: NAD(+) kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MQRIGMVANLEKPRVRETALDIINYLESRNVRVLISTRKAAALGCPEKGVAEEEVIAAEGLLALGGDGTLLRAARLVAPA
GTPILGINLGHLGFLTEIELTELYPALDKLLAGAYRIEERMMLRGTVQRPEKALTCTALNDIVVTKGAFSRMLRLEVYID
TAYLDTYPADGLIVSSPTGSTAYSLSAGGPLVSPQLQVMILTPICPHTLYTRPLVVPGEQEIRVCVHAPGAEVMLTVDGQ
QGLHLRDGDVIRVTRARTPARLIRLQDNTFYSLVREKLKEGGSRQDDENPAATVNPETDSKYPHSHPGSTG

Sequences:

>Translated_311_residues
MQRIGMVANLEKPRVRETALDIINYLESRNVRVLISTRKAAALGCPEKGVAEEEVIAAEGLLALGGDGTLLRAARLVAPA
GTPILGINLGHLGFLTEIELTELYPALDKLLAGAYRIEERMMLRGTVQRPEKALTCTALNDIVVTKGAFSRMLRLEVYID
TAYLDTYPADGLIVSSPTGSTAYSLSAGGPLVSPQLQVMILTPICPHTLYTRPLVVPGEQEIRVCVHAPGAEVMLTVDGQ
QGLHLRDGDVIRVTRARTPARLIRLQDNTFYSLVREKLKEGGSRQDDENPAATVNPETDSKYPHSHPGSTG
>Mature_311_residues
MQRIGMVANLEKPRVRETALDIINYLESRNVRVLISTRKAAALGCPEKGVAEEEVIAAEGLLALGGDGTLLRAARLVAPA
GTPILGINLGHLGFLTEIELTELYPALDKLLAGAYRIEERMMLRGTVQRPEKALTCTALNDIVVTKGAFSRMLRLEVYID
TAYLDTYPADGLIVSSPTGSTAYSLSAGGPLVSPQLQVMILTPICPHTLYTRPLVVPGEQEIRVCVHAPGAEVMLTVDGQ
QGLHLRDGDVIRVTRARTPARLIRLQDNTFYSLVREKLKEGGSRQDDENPAATVNPETDSKYPHSHPGSTG

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family

Homologues:

Organism=Homo sapiens, GI55743112, Length=247, Percent_Identity=30.3643724696356, Blast_Score=103, Evalue=2e-22,
Organism=Escherichia coli, GI1788968, Length=285, Percent_Identity=33.3333333333333, Blast_Score=154, Evalue=6e-39,
Organism=Saccharomyces cerevisiae, GI6320794, Length=260, Percent_Identity=32.3076923076923, Blast_Score=136, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6322509, Length=274, Percent_Identity=29.1970802919708, Blast_Score=125, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6325068, Length=212, Percent_Identity=33.4905660377358, Blast_Score=122, Evalue=8e-29,
Organism=Drosophila melanogaster, GI28573828, Length=238, Percent_Identity=33.1932773109244, Blast_Score=107, Evalue=7e-24,
Organism=Drosophila melanogaster, GI161077047, Length=238, Percent_Identity=33.1932773109244, Blast_Score=107, Evalue=8e-24,
Organism=Drosophila melanogaster, GI28573832, Length=238, Percent_Identity=33.1932773109244, Blast_Score=107, Evalue=8e-24,
Organism=Drosophila melanogaster, GI28573830, Length=238, Percent_Identity=33.1932773109244, Blast_Score=107, Evalue=9e-24,
Organism=Drosophila melanogaster, GI28573826, Length=238, Percent_Identity=33.1932773109244, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI20129957, Length=252, Percent_Identity=28.1746031746032, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24653422, Length=254, Percent_Identity=27.9527559055118, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI281363321, Length=255, Percent_Identity=27.843137254902, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI281363323, Length=255, Percent_Identity=27.843137254902, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24653424, Length=255, Percent_Identity=27.843137254902, Blast_Score=96, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPNK_MOOTA (Q2RIC1)

Other databases:

- EMBL:   CP000232
- RefSeq:   YP_430361.1
- ProteinModelPortal:   Q2RIC1
- SMR:   Q2RIC1
- STRING:   Q2RIC1
- GeneID:   3831974
- GenomeReviews:   CP000232_GR
- KEGG:   mta:Moth_1509
- NMPDR:   fig|264732.9.peg.1513
- eggNOG:   COG0061
- HOGENOM:   HBG713904
- OMA:   CVPEGFD
- PhylomeDB:   Q2RIC1
- BioCyc:   MTHE264732:MOTH_1509-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00361
- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504
- Gene3D:   G3DSA:2.60.200.30
- Gene3D:   G3DSA:3.40.50.10330
- PANTHER:   PTHR20275

Pfam domain/function: PF01513 NAD_kinase; SSF111331 ATP-NAD_kinase_PpnK-typ

EC number: =2.7.1.23

Molecular weight: Translated: 33684; Mature: 33684

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRIGMVANLEKPRVRETALDIINYLESRNVRVLISTRKAAALGCPEKGVAEEEVIAAEG
CCCCCCEECCCCCHHHHHHHHHHHHHHCCCEEEEEEECCHHCCCCCCCCCCHHHHHHHCC
LLALGGDGTLLRAARLVAPAGTPILGINLGHLGFLTEIELTELYPALDKLLAGAYRIEER
EEEECCCCHHHHHHHHCCCCCCCEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHH
MMLRGTVQRPEKALTCTALNDIVVTKGAFSRMLRLEVYIDTAYLDTYPADGLIVSSPTGS
HHHHHCCCCCCCEEEEEECCCEEEECHHHHEEEEEEEEEEEEEECCCCCCCEEEECCCCC
TAYSLSAGGPLVSPQLQVMILTPICPHTLYTRPLVVPGEQEIRVCVHAPGAEVMLTVDGQ
CEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCEEECCCCEEEEEEECCCCEEEEEECCC
QGLHLRDGDVIRVTRARTPARLIRLQDNTFYSLVREKLKEGGSRQDDENPAATVNPETDS
CCCEECCCCEEEEECCCCCEEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCC
KYPHSHPGSTG
CCCCCCCCCCC
>Mature Secondary Structure
MQRIGMVANLEKPRVRETALDIINYLESRNVRVLISTRKAAALGCPEKGVAEEEVIAAEG
CCCCCCEECCCCCHHHHHHHHHHHHHHCCCEEEEEEECCHHCCCCCCCCCCHHHHHHHCC
LLALGGDGTLLRAARLVAPAGTPILGINLGHLGFLTEIELTELYPALDKLLAGAYRIEER
EEEECCCCHHHHHHHHCCCCCCCEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHH
MMLRGTVQRPEKALTCTALNDIVVTKGAFSRMLRLEVYIDTAYLDTYPADGLIVSSPTGS
HHHHHCCCCCCCEEEEEECCCEEEECHHHHEEEEEEEEEEEEEECCCCCCCEEEECCCCC
TAYSLSAGGPLVSPQLQVMILTPICPHTLYTRPLVVPGEQEIRVCVHAPGAEVMLTVDGQ
CEEEECCCCCCCCCCEEEEEECCCCCCCCCCCCEEECCCCEEEEEEECCCCEEEEEECCC
QGLHLRDGDVIRVTRARTPARLIRLQDNTFYSLVREKLKEGGSRQDDENPAATVNPETDS
CCCEECCCCEEEEECCCCCEEEEEEECCHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCC
KYPHSHPGSTG
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA