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The map label for this gene is pabB [H]

Identifier: 82750416

GI number: 82750416

Start: 727186

End: 728346

Strand: Direct

Name: pabB [H]

Synonym: SAB0663

Alternate gene names: 82750416

Gene position: 727186-728346 (Clockwise)

Preceding gene: 82750415

Following gene: 82750417

Centisome position: 26.52

GC content: 32.13

Gene sequence:

>1161_bases
GTGATTACTGTGAGAATAGAATATAATTATCGCTACTATTTAACTGAAAATGAATATAAGCAATACCATATTCAATTAAA
GGGATTTATAAAGAAGTATGTTGCCACTAAGTTGGCTGATGTGGGAGAAGTGATACACTTTGCACAAGCGCAGCAACGAC
AAGGTAGATATGTTTCGTTATATTTAAGTTACGAAGCGGCAAAGTATTTTAATCATGTTATGTGTACACATTCATTAGCT
AAAGATGATATTTATGCAGTAGCTTATAGTTTTGAAAAAGCGGAAAGCATAAATTCAACATATGAACATCAAACTTATTA
TGTATCAAAGCATCATTTTTCATTTGTTGAATCTTCTGAGGTTATGATGACTAATATTAAACGTGTCCAACAAGCAATTG
TTGAAGGCGAAACGTATCAAGTGAACTATACGGCGCGCTTAAAGGATAACATTTATTATCCTATTAGTACTTTATATGAA
CGATTAACTCAATTTAGTAATGGTAATTATACTGCGTTATTACAAACAGATGAAATCCAAGTAGCGTCTATCTCACCAGA
ATTATTTTTTCAAAAAGGACAGTTTAACAATGTCGATAACGTTATCATAAGCAAACCGATGAAAGGGACAATGCCTAGAG
GTAAAACGGAAGCTGAAGATCAACAGTATTATAAAACATTGCAAACTTCTTCGAAAGATCGTGCAGAAAATGTCATGATT
GTTGATTTACTAAGAAACGATATAGGGAGAATATCACAGAGTGGCTCAATTAAGGTGTATAAACTTTTTTTCATTGAGGC
ATATAAAACTGTATTTCAAATGACTTCGATGGTAAGTGGAACTTTAAAAACTAATACAGACTTAACTCAAATTTTAACAT
CGTTATTTCCTTGTGGTTCGATTACAGGTGCACCGAAACTGAATACAATGAAATATATTAAACAATTAGAAAGTTCACCT
CGTGGTATATACTGCGGAGCAATTGGACTATTACTTCCAACTGAAGATGATAAAATGATTTTTAATATTCCGATTCGTAC
TATTGAGTATAAATATGGACAAGCGATTTATGGAGTCGGAGCAGGTATTACAATTGATTCTAAGCCAAAAGATGAAGTAA
ATGAATTTTACGCAAAAACCAAGATTTTGGAGATGTTATAA

Upstream 100 bases:

>100_bases
GAGCATATTACATTTCCGGTTTTTGGTGTGCAATATCATCCTGAATCTATTTTGAGTGAATACGGTTATCGACAAGTTGA
ATTATTTTTATCGAAGGTAG

Downstream 100 bases:

>100_bases
TGCAATTATTTGAAACAATGAAAATTGATAATGGACATATCCCTAGACTTACTTATCATACTAATCGCATAAAATGTTCT
TCCGAGCGATTAAACTTTAA

Product: anthranilate/para-aminobenzoate synthase component I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MITVRIEYNYRYYLTENEYKQYHIQLKGFIKKYVATKLADVGEVIHFAQAQQRQGRYVSLYLSYEAAKYFNHVMCTHSLA
KDDIYAVAYSFEKAESINSTYEHQTYYVSKHHFSFVESSEVMMTNIKRVQQAIVEGETYQVNYTARLKDNIYYPISTLYE
RLTQFSNGNYTALLQTDEIQVASISPELFFQKGQFNNVDNVIISKPMKGTMPRGKTEAEDQQYYKTLQTSSKDRAENVMI
VDLLRNDIGRISQSGSIKVYKLFFIEAYKTVFQMTSMVSGTLKTNTDLTQILTSLFPCGSITGAPKLNTMKYIKQLESSP
RGIYCGAIGLLLPTEDDKMIFNIPIRTIEYKYGQAIYGVGAGITIDSKPKDEVNEFYAKTKILEML

Sequences:

>Translated_386_residues
MITVRIEYNYRYYLTENEYKQYHIQLKGFIKKYVATKLADVGEVIHFAQAQQRQGRYVSLYLSYEAAKYFNHVMCTHSLA
KDDIYAVAYSFEKAESINSTYEHQTYYVSKHHFSFVESSEVMMTNIKRVQQAIVEGETYQVNYTARLKDNIYYPISTLYE
RLTQFSNGNYTALLQTDEIQVASISPELFFQKGQFNNVDNVIISKPMKGTMPRGKTEAEDQQYYKTLQTSSKDRAENVMI
VDLLRNDIGRISQSGSIKVYKLFFIEAYKTVFQMTSMVSGTLKTNTDLTQILTSLFPCGSITGAPKLNTMKYIKQLESSP
RGIYCGAIGLLLPTEDDKMIFNIPIRTIEYKYGQAIYGVGAGITIDSKPKDEVNEFYAKTKILEML
>Mature_386_residues
MITVRIEYNYRYYLTENEYKQYHIQLKGFIKKYVATKLADVGEVIHFAQAQQRQGRYVSLYLSYEAAKYFNHVMCTHSLA
KDDIYAVAYSFEKAESINSTYEHQTYYVSKHHFSFVESSEVMMTNIKRVQQAIVEGETYQVNYTARLKDNIYYPISTLYE
RLTQFSNGNYTALLQTDEIQVASISPELFFQKGQFNNVDNVIISKPMKGTMPRGKTEAEDQQYYKTLQTSSKDRAENVMI
VDLLRNDIGRISQSGSIKVYKLFFIEAYKTVFQMTSMVSGTLKTNTDLTQILTSLFPCGSITGAPKLNTMKYIKQLESSP
RGIYCGAIGLLLPTEDDKMIFNIPIRTIEYKYGQAIYGVGAGITIDSKPKDEVNEFYAKTKILEML

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=262, Percent_Identity=36.6412213740458, Blast_Score=165, Evalue=6e-42,
Organism=Escherichia coli, GI1787518, Length=262, Percent_Identity=29.0076335877863, Blast_Score=108, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6320935, Length=293, Percent_Identity=32.4232081911263, Blast_Score=135, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6324361, Length=284, Percent_Identity=25.3521126760563, Blast_Score=70, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 44399; Mature: 44399

Theoretical pI: Translated: 8.54; Mature: 8.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITVRIEYNYRYYLTENEYKQYHIQLKGFIKKYVATKLADVGEVIHFAQAQQRQGRYVSL
CEEEEEEEEEEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
YLSYEAAKYFNHVMCTHSLAKDDIYAVAYSFEKAESINSTYEHQTYYVSKHHFSFVESSE
EEEEHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHCCCCCCCEEEEECCEEEHHCCCH
VMMTNIKRVQQAIVEGETYQVNYTARLKDNIYYPISTLYERLTQFSNGNYTALLQTDEIQ
HHHHHHHHHHHHHHCCCEEEEEEEEEECCCEEECHHHHHHHHHHCCCCCEEEEEEECCEE
VASISPELFFQKGQFNNVDNVIISKPMKGTMPRGKTEAEDQQYYKTLQTSSKDRAENVMI
EEEECHHHEEECCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHCCEEE
VDLLRNDIGRISQSGSIKVYKLFFIEAYKTVFQMTSMVSGTLKTNTDLTQILTSLFPCGS
HHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCC
ITGAPKLNTMKYIKQLESSPRGIYCGAIGLLLPTEDDKMIFNIPIRTIEYKYGQAIYGVG
CCCCCCCHHHHHHHHHHCCCCEEEEEEEEEEEECCCCCEEEEECEEEEEEECCCEEEECC
AGITIDSKPKDEVNEFYAKTKILEML
CCEEECCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MITVRIEYNYRYYLTENEYKQYHIQLKGFIKKYVATKLADVGEVIHFAQAQQRQGRYVSL
CEEEEEEEEEEEEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
YLSYEAAKYFNHVMCTHSLAKDDIYAVAYSFEKAESINSTYEHQTYYVSKHHFSFVESSE
EEEEHHHHHHHHHHHHHHHCCCCEEEEEEEHHHHHHHCCCCCCCEEEEECCEEEHHCCCH
VMMTNIKRVQQAIVEGETYQVNYTARLKDNIYYPISTLYERLTQFSNGNYTALLQTDEIQ
HHHHHHHHHHHHHHCCCEEEEEEEEEECCCEEECHHHHHHHHHHCCCCCEEEEEEECCEE
VASISPELFFQKGQFNNVDNVIISKPMKGTMPRGKTEAEDQQYYKTLQTSSKDRAENVMI
EEEECHHHEEECCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHCCEEE
VDLLRNDIGRISQSGSIKVYKLFFIEAYKTVFQMTSMVSGTLKTNTDLTQILTSLFPCGS
HHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCC
ITGAPKLNTMKYIKQLESSPRGIYCGAIGLLLPTEDDKMIFNIPIRTIEYKYGQAIYGVG
CCCCCCCHHHHHHHHHHCCCCEEEEEEEEEEEECCCCCEEEEECEEEEEEECCCEEEECC
AGITIDSKPKDEVNEFYAKTKILEML
CCEEECCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]