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The map label for this gene is trpGD [H]

Identifier: 82750415

GI number: 82750415

Start: 726618

End: 727211

Strand: Direct

Name: trpGD [H]

Synonym: SAB0662

Alternate gene names: 82750415

Gene position: 726618-727211 (Clockwise)

Preceding gene: 82750406

Following gene: 82750416

Centisome position: 26.49

GC content: 33.5

Gene sequence:

>594_bases
ATGATTCTAGTCATAGATAATAATGATTCATTTACATATAATTTAATAGACTATATTAAGACTCAAACGAAACTAACAGT
TCAAGTTGTTGGTATTGATAATCTGCTGATAGAAGACGTCATTAATATGAAGCCAAATGCAATTGTTATTTCACCTGGGC
CGGGTAATCCGGATGATTATCCTATCTTGAATGAAGTGTTAGAACAATTTTATCAGCGTGTACCTATCCTAGGTGTATGT
TTAGGATTTCAATGTATCGTGTCTTATTTTGGTGGAAATATAATTCACGGCTATCATCCTGTACACGGACATACTACACA
GTTACGCCATACCAATGAAGGTATTTTTCAAGGACTGCCTCAAAATTTCAATGTAATGCGTTATCATTCATTAATTGCTG
ACGGAGCGACTTTTCCAAATTGCTTAAAGATTACAGCAAAAAATGATGAAGCGATTATTATGGCATTTGAGCATATTACA
TTTCCGGTTTTTGGTGTGCAATATCATCCTGAATCTATTTTGAGTGAATACGGTTATCGACAAGTTGAATTATTTTTATC
GAAGGTAGGTGATTACTGTGAGAATAGAATATAA

Upstream 100 bases:

>100_bases
TTAGTTAAAATCAAGGTCAGGATAATGACAATGCTTTTAAAGTTTTAGCTACATCCAATACATATTATAAAAATAAAACA
CATTTAGAACGGAGTATACA

Downstream 100 bases:

>100_bases
TTATCGCTACTATTTAACTGAAAATGAATATAAGCAATACCATATTCAATTAAAGGGATTTATAAAGAAGTATGTTGCCA
CTAAGTTGGCTGATGTGGGA

Product: anthranilate/para-aminobenzoate synthase component II

Products: NA

Alternate protein names: Glutamine amidotransferase; Anthranilate phosphoribosyltransferase [H]

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MILVIDNNDSFTYNLIDYIKTQTKLTVQVVGIDNLLIEDVINMKPNAIVISPGPGNPDDYPILNEVLEQFYQRVPILGVC
LGFQCIVSYFGGNIIHGYHPVHGHTTQLRHTNEGIFQGLPQNFNVMRYHSLIADGATFPNCLKITAKNDEAIIMAFEHIT
FPVFGVQYHPESILSEYGYRQVELFLSKVGDYCENRI

Sequences:

>Translated_197_residues
MILVIDNNDSFTYNLIDYIKTQTKLTVQVVGIDNLLIEDVINMKPNAIVISPGPGNPDDYPILNEVLEQFYQRVPILGVC
LGFQCIVSYFGGNIIHGYHPVHGHTTQLRHTNEGIFQGLPQNFNVMRYHSLIADGATFPNCLKITAKNDEAIIMAFEHIT
FPVFGVQYHPESILSEYGYRQVELFLSKVGDYCENRI
>Mature_197_residues
MILVIDNNDSFTYNLIDYIKTQTKLTVQVVGIDNLLIEDVINMKPNAIVISPGPGNPDDYPILNEVLEQFYQRVPILGVC
LGFQCIVSYFGGNIIHGYHPVHGHTTQLRHTNEGIFQGLPQNFNVMRYHSLIADGATFPNCLKITAKNDEAIIMAFEHIT
FPVFGVQYHPESILSEYGYRQVELFLSKVGDYCENRI

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=188, Percent_Identity=42.5531914893617, Blast_Score=159, Evalue=9e-41,
Organism=Escherichia coli, GI1787517, Length=198, Percent_Identity=36.3636363636364, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI1786215, Length=139, Percent_Identity=28.7769784172662, Blast_Score=61, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322638, Length=197, Percent_Identity=38.5786802030457, Blast_Score=156, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6324361, Length=210, Percent_Identity=34.2857142857143, Blast_Score=88, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase; PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =4.1.3.27; =2.4.2.18 [H]

Molecular weight: Translated: 22309; Mature: 22309

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILVIDNNDSFTYNLIDYIKTQTKLTVQVVGIDNLLIEDVINMKPNAIVISPGPGNPDDY
CEEEEECCCCEEEHHHHHHHCCCEEEEEEEECCHHHHHHHHCCCCCEEEEECCCCCCCCC
PILNEVLEQFYQRVPILGVCLGFQCIVSYFGGNIIHGYHPVHGHTTQLRHTNEGIFQGLP
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEECEECCCCCCEEEEECCCHHHHCCC
QNFNVMRYHSLIADGATFPNCLKITAKNDEAIIMAFEHITFPVFGVQYHPESILSEYGYR
CCCCHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEECCEEEEEEEEECHHHHHHHCCCH
QVELFLSKVGDYCENRI
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MILVIDNNDSFTYNLIDYIKTQTKLTVQVVGIDNLLIEDVINMKPNAIVISPGPGNPDDY
CEEEEECCCCEEEHHHHHHHCCCEEEEEEEECCHHHHHHHHCCCCCEEEEECCCCCCCCC
PILNEVLEQFYQRVPILGVCLGFQCIVSYFGGNIIHGYHPVHGHTTQLRHTNEGIFQGLP
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCEEECEECCCCCCEEEEECCCHHHHCCC
QNFNVMRYHSLIADGATFPNCLKITAKNDEAIIMAFEHITFPVFGVQYHPESILSEYGYR
CCCCHHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEECCEEEEEEEEECHHHHHHHCCCH
QVELFLSKVGDYCENRI
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685830; 10360571; 7556082 [H]