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The map label for this gene is dhaK [H]

Identifier: 82750352

GI number: 82750352

Start: 665766

End: 666734

Strand: Direct

Name: dhaK [H]

Synonym: SAB0599

Alternate gene names: 82750352

Gene position: 665766-666734 (Clockwise)

Preceding gene: 82750351

Following gene: 82750353

Centisome position: 24.28

GC content: 35.09

Gene sequence:

>969_bases
ATGATGAAAAAGTTAATCAATAAAAAAGAAACATTTTTAACTGATATGCTTGAAGGATTGTTAATTGTGCACCCAGAGTT
AGATCTGATTGCTAATACAGTTATTGTAAAAAAAGCTAAAAAAGAAAAAGGTGTAGCAATAGTCTCTGGAGGTGGAAGCG
GACATGAACCTGCGCATGCCGGTTTTGTTGCAGAAGGTATGCTAGATGCAACGGTTTGTGGCGAAGTATTTACATCACCT
ACACCAGATAAAATATTAGAAGCTATTAAAGCAGTAGATAATGGTGATGGTGTATTACTAGTTGTAAAAAACTATGCAGG
TGACGTGATGAATTTCGAAATGGCACAAGAGCTTGCAGAAATGGAAGATATAAATGTTGAAACTGTTATTGTTCGTGACG
ACATTGCTGTGACAAACGAAGCACAACGTCGTGGTGTTGCAGGAACGGTGTTTGTTCATAAGTTTGCTGGTTATCTTGCT
GAAAAAGGTTATTCATTAACAGAGATTAAATCGCGTGTAGAAGCGTTGTTACCTGAAATTAAAAGTATTGGTATGGCAAT
TGAACCACCGCTTGTTCCAACTACTGGAAAATATGGCTTTGATATTGAAGACGACAAAATGGAAATCGGTATTGGTATAC
ATGGTGAAAAAGGTATTCATAGGGAAGAAGTAAAGGATATTGATCATATTGTTGGAACATTATTAGACGAATTGTATAAA
GAAGTTACTGCCAATGATGTCATATTAATGGTAAATGGTATGGGTGGTACGCCGTTATCTGAATTAAATATCGTAACTAA
ATATATTCAACAAAATTTGGCTGCAAGAACGGTTAATGTTGCTAAATGGTTTGTTGGTGATTATATGACATCTCTAGACA
TGCAAGGTTTTTCTATAACTATCGTGCCTAATAAACCAGAATATTTGGAAGCATTTTTAGCACCAACAACAAGTCAATAC
TTTAAATAA

Upstream 100 bases:

>100_bases
TCAAAAATATATTTGATAACGGTATCAGGTTAATTCTTTATGATAGCGCATTCATTTATTCTGTTTTATACTATGACTGA
TAATACCAAGGAGGTACAAC

Downstream 100 bases:

>100_bases
GAAGTGAATATGAATAAATATACATTTATGAGGTGACACAAATGAAAGTGAATGATATGAAAGCACGTTTATTAAATTTA
GAAGAAACGTTTAAAAAACA

Product: dihydroxyacetone kinase subunit DhaK

Products: ADP; glycerone phosphate

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MMKKLINKKETFLTDMLEGLLIVHPELDLIANTVIVKKAKKEKGVAIVSGGGSGHEPAHAGFVAEGMLDATVCGEVFTSP
TPDKILEAIKAVDNGDGVLLVVKNYAGDVMNFEMAQELAEMEDINVETVIVRDDIAVTNEAQRRGVAGTVFVHKFAGYLA
EKGYSLTEIKSRVEALLPEIKSIGMAIEPPLVPTTGKYGFDIEDDKMEIGIGIHGEKGIHREEVKDIDHIVGTLLDELYK
EVTANDVILMVNGMGGTPLSELNIVTKYIQQNLAARTVNVAKWFVGDYMTSLDMQGFSITIVPNKPEYLEAFLAPTTSQY
FK

Sequences:

>Translated_322_residues
MMKKLINKKETFLTDMLEGLLIVHPELDLIANTVIVKKAKKEKGVAIVSGGGSGHEPAHAGFVAEGMLDATVCGEVFTSP
TPDKILEAIKAVDNGDGVLLVVKNYAGDVMNFEMAQELAEMEDINVETVIVRDDIAVTNEAQRRGVAGTVFVHKFAGYLA
EKGYSLTEIKSRVEALLPEIKSIGMAIEPPLVPTTGKYGFDIEDDKMEIGIGIHGEKGIHREEVKDIDHIVGTLLDELYK
EVTANDVILMVNGMGGTPLSELNIVTKYIQQNLAARTVNVAKWFVGDYMTSLDMQGFSITIVPNKPEYLEAFLAPTTSQY
FK
>Mature_322_residues
MMKKLINKKETFLTDMLEGLLIVHPELDLIANTVIVKKAKKEKGVAIVSGGGSGHEPAHAGFVAEGMLDATVCGEVFTSP
TPDKILEAIKAVDNGDGVLLVVKNYAGDVMNFEMAQELAEMEDINVETVIVRDDIAVTNEAQRRGVAGTVFVHKFAGYLA
EKGYSLTEIKSRVEALLPEIKSIGMAIEPPLVPTTGKYGFDIEDDKMEIGIGIHGEKGIHREEVKDIDHIVGTLLDELYK
EVTANDVILMVNGMGGTPLSELNIVTKYIQQNLAARTVNVAKWFVGDYMTSLDMQGFSITIVPNKPEYLEAFLAPTTSQY
FK

Specific function: Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone [H]

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaK domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=334, Percent_Identity=39.5209580838323, Blast_Score=228, Evalue=7e-60,
Organism=Escherichia coli, GI87081857, Length=346, Percent_Identity=40.4624277456647, Blast_Score=240, Evalue=7e-65,
Organism=Caenorhabditis elegans, GI17565018, Length=327, Percent_Identity=31.8042813455657, Blast_Score=173, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6321055, Length=343, Percent_Identity=34.402332361516, Blast_Score=167, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6323570, Length=320, Percent_Identity=34.0625, Blast_Score=162, Evalue=5e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004006
- InterPro:   IPR012736 [H]

Pfam domain/function: PF02733 Dak1 [H]

EC number: 2.7.1.29

Molecular weight: Translated: 35146; Mature: 35146

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKKLINKKETFLTDMLEGLLIVHPELDLIANTVIVKKAKKEKGVAIVSGGGSGHEPAHA
CCHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCC
GFVAEGMLDATVCGEVFTSPTPDKILEAIKAVDNGDGVLLVVKNYAGDVMNFEMAQELAE
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHH
MEDINVETVIVRDDIAVTNEAQRRGVAGTVFVHKFAGYLAEKGYSLTEIKSRVEALLPEI
HHCCCEEEEEEECCCEECCHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
KSIGMAIEPPLVPTTGKYGFDIEDDKMEIGIGIHGEKGIHREEVKDIDHIVGTLLDELYK
HHCCCEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
EVTANDVILMVNGMGGTPLSELNIVTKYIQQNLAARTVNVAKWFVGDYMTSLDMQGFSIT
HHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
IVPNKPEYLEAFLAPTTSQYFK
EECCCHHHHHHHHCCCHHHHCC
>Mature Secondary Structure
MMKKLINKKETFLTDMLEGLLIVHPELDLIANTVIVKKAKKEKGVAIVSGGGSGHEPAHA
CCHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCC
GFVAEGMLDATVCGEVFTSPTPDKILEAIKAVDNGDGVLLVVKNYAGDVMNFEMAQELAE
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHH
MEDINVETVIVRDDIAVTNEAQRRGVAGTVFVHKFAGYLAEKGYSLTEIKSRVEALLPEI
HHCCCEEEEEEECCCEECCHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
KSIGMAIEPPLVPTTGKYGFDIEDDKMEIGIGIHGEKGIHREEVKDIDHIVGTLLDELYK
HHCCCEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
EVTANDVILMVNGMGGTPLSELNIVTKYIQQNLAARTVNVAKWFVGDYMTSLDMQGFSIT
HHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
IVPNKPEYLEAFLAPTTSQYFK
EECCCHHHHHHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; glycerone

Specific reaction: ATP + glycerone = ADP + glycerone phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]