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The map label for this gene is fhuD

Identifier: 82750351

GI number: 82750351

Start: 664516

End: 665532

Strand: Direct

Name: fhuD

Synonym: SAB0598

Alternate gene names: 82750351

Gene position: 664516-665532 (Clockwise)

Preceding gene: 82750350

Following gene: 82750352

Centisome position: 24.23

GC content: 35.59

Gene sequence:

>1017_bases
ATGATTAGTTCAAATAATAAACGCAGACAATGGATAGCACTGGCTGTTTTTAGCATTCTACTATTTCTAGGTTGTACTTG
GAGTATTACCTCAGGTGAATACAACATACCTGTAGAAAGATTTTTCAAAACTTTAATTGGACAAGGTGATGCCATTGATG
AGTTAATCTTATTAGATTTCAGATTACCTCGGATGATGATTACTATTTTGGCAGGCGTAACGCTTAGTATTAGTGGTGCA
ATAGTGCAAAGTGTCACGAAAAATCCAATAGCTGAACCAGGTATATTAGGTATTAACGCAGGCGGCGGATTTGCAATCGC
ATTATTTATTGCAATTGGTAAAATTAATGCTGACAATTTTGTTTATGTACTGCCGCTAATAAGTATACTAGGTGGTATCA
CCGCTGCATTGATTATTTTTATTTTCAGTTTTAATAAAAATGAAGGTGTTACACCTGCGAGTATGGTATTAATAGGTGTA
GGTTTACAAACAGCATTATATGGTGGCTCAATTACAATTATGTCAAAATTTGATGATAAGCAATCTGATTTCATCGCTGC
TTGGTTTGCAGGTAATATTTGGGGTGACGAATGGCCATTTGTCATTGCATTTTTACCGTGGGTGTTGATTATTATTCCTT
ACTTACTATTTAAATCGAATACACTAAATATTATTCATACAGGTGATAATATTGCACGAGGTCTAGGTGTAAGGTTAAGC
AGAGAACGTTTAATATTATTCTTTATCGCAGTGATGTTATCATCTGCTGCTGTAGCAGTAGCAGGTTCAATTTCGTTTAT
CGGATTAATGGGCCCGCATATTGCCAAACGTATCGTTGGACCACGTCACCAGTTGTTTTTACCAATTGCCATTTTAGTAG
GGGCATGTTTACTTGTTATAGCTGATACAATTGGCAAAATTATATTACAACCAGGTGGGGTTCCAGCAGGTATTGTCGTA
GCAATTATTGGTGCACCGTATTTCTTATATTTAATGTACAAAACGAAAAATGTATAG

Upstream 100 bases:

>100_bases
TGATAGCACGATATTTAGGAGAAGCGCCTGTTGGTGCAATCATTTCATTTATCGGTGTTCCTTGCTTTTTATATTTAGTT
AAAAAAGGAGGACGCACAAT

Downstream 100 bases:

>100_bases
TGTCAAAGGACACAACTTATTGCTATGAAAGGCACTTTATTATAAGGCTTTTCATAGCATTTTTTATTTAATGAGCCACT
CAAGACTATTTATTTTTTCA

Product: ferrichrome transport permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein G; Ferrichrome transport system permease protein fhuG; Iron(III)-hydroxamate import system permease protein fhuG [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MISSNNKRRQWIALAVFSILLFLGCTWSITSGEYNIPVERFFKTLIGQGDAIDELILLDFRLPRMMITILAGVTLSISGA
IVQSVTKNPIAEPGILGINAGGGFAIALFIAIGKINADNFVYVLPLISILGGITAALIIFIFSFNKNEGVTPASMVLIGV
GLQTALYGGSITIMSKFDDKQSDFIAAWFAGNIWGDEWPFVIAFLPWVLIIIPYLLFKSNTLNIIHTGDNIARGLGVRLS
RERLILFFIAVMLSSAAVAVAGSISFIGLMGPHIAKRIVGPRHQLFLPIAILVGACLLVIADTIGKIILQPGGVPAGIVV
AIIGAPYFLYLMYKTKNV

Sequences:

>Translated_338_residues
MISSNNKRRQWIALAVFSILLFLGCTWSITSGEYNIPVERFFKTLIGQGDAIDELILLDFRLPRMMITILAGVTLSISGA
IVQSVTKNPIAEPGILGINAGGGFAIALFIAIGKINADNFVYVLPLISILGGITAALIIFIFSFNKNEGVTPASMVLIGV
GLQTALYGGSITIMSKFDDKQSDFIAAWFAGNIWGDEWPFVIAFLPWVLIIIPYLLFKSNTLNIIHTGDNIARGLGVRLS
RERLILFFIAVMLSSAAVAVAGSISFIGLMGPHIAKRIVGPRHQLFLPIAILVGACLLVIADTIGKIILQPGGVPAGIVV
AIIGAPYFLYLMYKTKNV
>Mature_338_residues
MISSNNKRRQWIALAVFSILLFLGCTWSITSGEYNIPVERFFKTLIGQGDAIDELILLDFRLPRMMITILAGVTLSISGA
IVQSVTKNPIAEPGILGINAGGGFAIALFIAIGKINADNFVYVLPLISILGGITAALIIFIFSFNKNEGVTPASMVLIGV
GLQTALYGGSITIMSKFDDKQSDFIAAWFAGNIWGDEWPFVIAFLPWVLIIIPYLLFKSNTLNIIHTGDNIARGLGVRLS
RERLILFFIAVMLSSAAVAVAGSISFIGLMGPHIAKRIVGPRHQLFLPIAILVGACLLVIADTIGKIILQPGGVPAGIVV
AIIGAPYFLYLMYKTKNV

Specific function: Part of the ABC transporter complex fhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=333, Percent_Identity=32.1321321321321, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1790741, Length=297, Percent_Identity=32.996632996633, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1786805, Length=307, Percent_Identity=33.5504885993485, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1786347, Length=283, Percent_Identity=33.5689045936396, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1788004, Length=286, Percent_Identity=31.4685314685315, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1786804, Length=328, Percent_Identity=28.3536585365854, Blast_Score=113, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 36394; Mature: 36394

Theoretical pI: Translated: 9.75; Mature: 9.75

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00267 TACHYKININ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISSNNKRRQWIALAVFSILLFLGCTWSITSGEYNIPVERFFKTLIGQGDAIDELILLDF
CCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHCCCCCHHHHHHHHH
RLPRMMITILAGVTLSISGAIVQSVTKNPIAEPGILGINAGGGFAIALFIAIGKINADNF
HHHHHHHHHHHCHHHEECHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCE
VYVLPLISILGGITAALIIFIFSFNKNEGVTPASMVLIGVGLQTALYGGSITIMSKFDDK
EEHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHCCHHHHHCCCEEEEEECCCCC
QSDFIAAWFAGNIWGDEWPFVIAFLPWVLIIIPYLLFKSNTLNIIHTGDNIARGLGVRLS
CCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHCCCCEEC
RERLILFFIAVMLSSAAVAVAGSISFIGLMGPHIAKRIVGPRHQLFLPIAILVGACLLVI
HHHHHHHHHHHHHCCCHHHHHCCHHHHHHHCHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
ADTIGKIILQPGGVPAGIVVAIIGAPYFLYLMYKTKNV
HHHHHHHEECCCCCCHHHHHHHHHCCHHEEEEEECCCC
>Mature Secondary Structure
MISSNNKRRQWIALAVFSILLFLGCTWSITSGEYNIPVERFFKTLIGQGDAIDELILLDF
CCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHCCCCCHHHHHHHHH
RLPRMMITILAGVTLSISGAIVQSVTKNPIAEPGILGINAGGGFAIALFIAIGKINADNF
HHHHHHHHHHHCHHHEECHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCE
VYVLPLISILGGITAALIIFIFSFNKNEGVTPASMVLIGVGLQTALYGGSITIMSKFDDK
EEHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHCCHHHHHCCCEEEEEECCCCC
QSDFIAAWFAGNIWGDEWPFVIAFLPWVLIIIPYLLFKSNTLNIIHTGDNIARGLGVRLS
CCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHCCCCEEC
RERLILFFIAVMLSSAAVAVAGSISFIGLMGPHIAKRIVGPRHQLFLPIAILVGACLLVI
HHHHHHHHHHHHHCCCHHHHHCCHHHHHHHCHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
ADTIGKIILQPGGVPAGIVVAIIGAPYFLYLMYKTKNV
HHHHHHHEECCCCCCHHHHHHHHHCCHHEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]