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The map label for this gene is clpC

Identifier: 82750232

GI number: 82750232

Start: 531229

End: 533685

Strand: Direct

Name: clpC

Synonym: SAB0475

Alternate gene names: 82750232

Gene position: 531229-533685 (Clockwise)

Preceding gene: 82750231

Following gene: 82750233

Centisome position: 19.37

GC content: 34.19

Gene sequence:

>2457_bases
ATGTTATTTGGTAGATTAACTGAACGTGCACAGCGCGTATTAGCACATGCACAAGAAGAAGCAATTCGTTTAAATCATTC
AAATATAGGAACAGAACACCTATTATTGGGGTTAATGAAAGAACCTGAAGGAATTGCTGCAAAAGTATTAGAAAGTTTTA
ATATCACTGAAGATAAAGTAATTGAAGAAGTTGAAAAATTAATTGGACATGGTCAAGATCATGTTGGTACATTGCATTAT
ACACCTAGAGCTAAAAAAGTCATTGAATTATCGATGGATGAAGCTAGAAAATTACATCACAATTTTGTTGGAACGGAACA
TATTTTATTAGGCTTGATTCGTGAAAATGAAGGTGTTGCAGCAAGAGTTTTTGCAAATCTAGATTTAAATATTACTAAAG
CACGTGCACAAGTTGTGAAAGCTTTAGGAAACCCTGAAATGAGTAATAAAAATGCACAAGCTAGTAAGTCAAATAATACT
CCAACTTTAGATAGTTTAGCTCGTGACTTAACAGTCATTGCCAAAGACGGTACATTAGATCCTGTTATAGGACGTGATAA
AGAAATTACACGTGTAATTGAAGTATTAAGTAGACGTACGAAAAACAATCCTGTGCTTATTGGAGAGCCAGGTGTTGGTA
AAACTGCTATTGCTGAAGGTTTAGCGCAAGCCATAGTGAATAATGAGGTGCCAGAGACATTAAAAGATAAGCGTGTTATG
TCTTTAGATATGGGAACAGTAGTTGCAGGTACTAAATATCGTGGTGAATTTGAAGAGCGTCTGAAAAAGGTTATGGAAGA
AATCCAACAAGCAGGTAATGTCATCCTATTTATTGATGAGTTGCATACTTTAGTTGGTGCTGGTGGTGCTGAAGGTGCTA
TCGATGCTTCGAATATTTTGAAACCGGCATTAGCACGTGGTGAATTACAATGTATTGGTGCTACTACATTAGATGAATAT
CGCAAAAATATTGAAAAAGACGCGGCTTTAGAACGTCGTTTCCAACCTGTACAAGTTGATGAACCTTCAGTAGTAGATAC
AGTTGCTATTTTAAAAGGATTAAGAGATCGTTACGAAGCACACCATCGTATTAATATTTCAGACGAAGCTATTGAAGCGG
CTGTTAAATTAAGTAACAGATACGTTTCAGATCGTTTCTTACCAGATAAAGCAATTGATTTAATTGATGAAGCAAGTTCT
AAAGTAAGACTTAAGAGTCATACGACACCTAATAATTTAAAAGAAATTGAACAAGAGATTGAAAAAGTTAAAAATGAAAA
AGATGCCGCAGTACATGCTCAAGAGTTTGAAAATGCTGCTAATCTGCGTGATAAACAAACAAAACTTGAAAAGCAATATG
AAGAAGCTAAAAATGAATGGAAGAACACACAAAATGGCATGTCAACTTCATTGTCAGAAGAAGATATTGCTGAAGTCATT
GCAGGATGGACAGGTATCCCATTAACTAAAATCAATGAAACAGAATCTGAAAAACTTCTTAGTCTAGAAGATACATTACA
TGAGAGAGTTATTGGGCAAAAAGATGCTGTTAATTCAATCAGTAAAGCGGTTAGACGTGCCCGTGCAGGGTTAAAAGATC
CTAAACGACCAATTGGTAGCTTTATCTTCCTTGGACCAACTGGTGTTGGTAAAACTGAATTAGCTAGAGCTTTAGCTGAA
TCAATGTTCGGCGATGATGATGCGATGATTCGTGTAGACATGAGTGAATTTATGGAAAAACACGCAGTGAGCCGATTAGT
TGGTGCTCCTCCAGGATATGTTGGTCATGATGATGGTGGACAATTAACTGAAAAAGTTAGACGTAAACCATATTCTGTAA
TTTTATTTGATGAAATTGAAAAAGCACATCCAGATGTATTTAATATTCTATTACAAGTTTTAGATGATGGACATTTGACA
GATACAAAAGGACGTACAGTTGATTTCAGAAATACAATTATCATAATGACATCAAACGTTGGAGCACAAGAATTACAAGA
TCAACGATTTGCTGGATTCGGTGGTTCAAGTGATGGACAAGATTATGAAACAATTCGAAAAACGATGTTAAAAGAATTAA
AAAATTCATTCCGTCCAGAATTTTTAAACCGTGTAGATGATATCATTGTATTCCATAAACTAACAAAAGAAGAATTAAAA
GAAATTGTAACAATGATGGTTAATAAATTAACAAATCGATTATCCGAACAAAACATAAATATTATTGTTACTGATAAAGC
GAAAGACAAAATCGCAGAAGAAGGATATGATCCAGAATATGGTGCAAGACCATTAATTAGAGCGATACAAAAAACTATTG
AAGATAATTTAAGTGAATTAATATTAGATGGTAATCAAATTGAAGGTAAGAAAGTTACAGTAGATCATGATGGTAAAGAG
TTTAAATATGACATTGCTGAACAAACTTCAGAAACTAAAACACCATCGCAAGCATAA

Upstream 100 bases:

>100_bases
ATACAGTCACCATTTTTATTAGATGAAGAAGATGACAAATCTGTAAAAGAAAAACGAGCAGATATACTAAGAGAACATAT
AAAGTAGGAGGTCATTATTT

Downstream 100 bases:

>100_bases
TTATAAAACAGTCCAAAACAAATTAAAGTTTTGGGCTGTTTTTTTAGTAGCATTGAACTATAGAAATTCGTGAAAGTATC
CATCAACGAAACAATCTAAT

Product: endopeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 818; Mature: 818

Protein sequence:

>818_residues
MLFGRLTERAQRVLAHAQEEAIRLNHSNIGTEHLLLGLMKEPEGIAAKVLESFNITEDKVIEEVEKLIGHGQDHVGTLHY
TPRAKKVIELSMDEARKLHHNFVGTEHILLGLIRENEGVAARVFANLDLNITKARAQVVKALGNPEMSNKNAQASKSNNT
PTLDSLARDLTVIAKDGTLDPVIGRDKEITRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQAIVNNEVPETLKDKRVM
SLDMGTVVAGTKYRGEFEERLKKVMEEIQQAGNVILFIDELHTLVGAGGAEGAIDASNILKPALARGELQCIGATTLDEY
RKNIEKDAALERRFQPVQVDEPSVVDTVAILKGLRDRYEAHHRINISDEAIEAAVKLSNRYVSDRFLPDKAIDLIDEASS
KVRLKSHTTPNNLKEIEQEIEKVKNEKDAAVHAQEFENAANLRDKQTKLEKQYEEAKNEWKNTQNGMSTSLSEEDIAEVI
AGWTGIPLTKINETESEKLLSLEDTLHERVIGQKDAVNSISKAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALAE
SMFGDDDAMIRVDMSEFMEKHAVSRLVGAPPGYVGHDDGGQLTEKVRRKPYSVILFDEIEKAHPDVFNILLQVLDDGHLT
DTKGRTVDFRNTIIIMTSNVGAQELQDQRFAGFGGSSDGQDYETIRKTMLKELKNSFRPEFLNRVDDIIVFHKLTKEELK
EIVTMMVNKLTNRLSEQNINIIVTDKAKDKIAEEGYDPEYGARPLIRAIQKTIEDNLSELILDGNQIEGKKVTVDHDGKE
FKYDIAEQTSETKTPSQA

Sequences:

>Translated_818_residues
MLFGRLTERAQRVLAHAQEEAIRLNHSNIGTEHLLLGLMKEPEGIAAKVLESFNITEDKVIEEVEKLIGHGQDHVGTLHY
TPRAKKVIELSMDEARKLHHNFVGTEHILLGLIRENEGVAARVFANLDLNITKARAQVVKALGNPEMSNKNAQASKSNNT
PTLDSLARDLTVIAKDGTLDPVIGRDKEITRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQAIVNNEVPETLKDKRVM
SLDMGTVVAGTKYRGEFEERLKKVMEEIQQAGNVILFIDELHTLVGAGGAEGAIDASNILKPALARGELQCIGATTLDEY
RKNIEKDAALERRFQPVQVDEPSVVDTVAILKGLRDRYEAHHRINISDEAIEAAVKLSNRYVSDRFLPDKAIDLIDEASS
KVRLKSHTTPNNLKEIEQEIEKVKNEKDAAVHAQEFENAANLRDKQTKLEKQYEEAKNEWKNTQNGMSTSLSEEDIAEVI
AGWTGIPLTKINETESEKLLSLEDTLHERVIGQKDAVNSISKAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALAE
SMFGDDDAMIRVDMSEFMEKHAVSRLVGAPPGYVGHDDGGQLTEKVRRKPYSVILFDEIEKAHPDVFNILLQVLDDGHLT
DTKGRTVDFRNTIIIMTSNVGAQELQDQRFAGFGGSSDGQDYETIRKTMLKELKNSFRPEFLNRVDDIIVFHKLTKEELK
EIVTMMVNKLTNRLSEQNINIIVTDKAKDKIAEEGYDPEYGARPLIRAIQKTIEDNLSELILDGNQIEGKKVTVDHDGKE
FKYDIAEQTSETKTPSQA
>Mature_818_residues
MLFGRLTERAQRVLAHAQEEAIRLNHSNIGTEHLLLGLMKEPEGIAAKVLESFNITEDKVIEEVEKLIGHGQDHVGTLHY
TPRAKKVIELSMDEARKLHHNFVGTEHILLGLIRENEGVAARVFANLDLNITKARAQVVKALGNPEMSNKNAQASKSNNT
PTLDSLARDLTVIAKDGTLDPVIGRDKEITRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQAIVNNEVPETLKDKRVM
SLDMGTVVAGTKYRGEFEERLKKVMEEIQQAGNVILFIDELHTLVGAGGAEGAIDASNILKPALARGELQCIGATTLDEY
RKNIEKDAALERRFQPVQVDEPSVVDTVAILKGLRDRYEAHHRINISDEAIEAAVKLSNRYVSDRFLPDKAIDLIDEASS
KVRLKSHTTPNNLKEIEQEIEKVKNEKDAAVHAQEFENAANLRDKQTKLEKQYEEAKNEWKNTQNGMSTSLSEEDIAEVI
AGWTGIPLTKINETESEKLLSLEDTLHERVIGQKDAVNSISKAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALAE
SMFGDDDAMIRVDMSEFMEKHAVSRLVGAPPGYVGHDDGGQLTEKVRRKPYSVILFDEIEKAHPDVFNILLQVLDDGHLT
DTKGRTVDFRNTIIIMTSNVGAQELQDQRFAGFGGSSDGQDYETIRKTMLKELKNSFRPEFLNRVDDIIVFHKLTKEELK
EIVTMMVNKLTNRLSEQNINIIVTDKAKDKIAEEGYDPEYGARPLIRAIQKTIEDNLSELILDGNQIEGKKVTVDHDGKE
FKYDIAEQTSETKTPSQA

Specific function: Required for growth at high temperatures, probably by acting as a chaperone during heat shock and targeting heat- denatured proteins for degradation by ClpP [H]

COG id: COG0542

COG function: function code O; ATPases with chaperone activity, ATP-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain [H]

Homologues:

Organism=Homo sapiens, GI13540606, Length=301, Percent_Identity=38.8704318936877, Blast_Score=212, Evalue=1e-54,
Organism=Escherichia coli, GI1788943, Length=863, Percent_Identity=46.5816917728853, Blast_Score=711, Evalue=0.0,
Organism=Escherichia coli, GI1787109, Length=804, Percent_Identity=35.1990049751244, Blast_Score=458, Evalue=1e-130,
Organism=Saccharomyces cerevisiae, GI6320464, Length=697, Percent_Identity=48.9239598278336, Blast_Score=652, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6323002, Length=896, Percent_Identity=37.7232142857143, Blast_Score=551, Evalue=1e-157,

Paralogues:

None

Copy number: 560 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR003959
- InterPro:   IPR018368
- InterPro:   IPR001270
- InterPro:   IPR019489
- InterPro:   IPR004176
- InterPro:   IPR023150
- InterPro:   IPR001943 [H]

Pfam domain/function: PF00004 AAA; PF07724 AAA_2; PF02861 Clp_N; PF10431 ClpB_D2-small; PF02151 UVR [H]

EC number: NA

Molecular weight: Translated: 91069; Mature: 91069

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS50151 UVR ; PS00870 CLPAB_1 ; PS00871 CLPAB_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFGRLTERAQRVLAHAQEEAIRLNHSNIGTEHLLLGLMKEPEGIAAKVLESFNITEDKV
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCHHHH
IEEVEKLIGHGQDHVGTLHYTPRAKKVIELSMDEARKLHHNFVGTEHILLGLIRENEGVA
HHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCE
ARVFANLDLNITKARAQVVKALGNPEMSNKNAQASKSNNTPTLDSLARDLTVIAKDGTLD
EEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHEEEECCCCCC
PVIGRDKEITRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQAIVNNEVPETLKDKRVM
CCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHCEEE
SLDMGTVVAGTKYRGEFEERLKKVMEEIQQAGNVILFIDELHTLVGAGGAEGAIDASNIL
EECCCCEEECCCCCCHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHCCCCCCCCCCHHHHH
KPALARGELQCIGATTLDEYRKNIEKDAALERRFQPVQVDEPSVVDTVAILKGLRDRYEA
HHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
HHRINISDEAIEAAVKLSNRYVSDRFLPDKAIDLIDEASSKVRLKSHTTPNNLKEIEQEI
HCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHH
EKVKNEKDAAVHAQEFENAANLRDKQTKLEKQYEEAKNEWKNTQNGMSTSLSEEDIAEVI
HHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
AGWTGIPLTKINETESEKLLSLEDTLHERVIGQKDAVNSISKAVRRARAGLKDPKRPIGS
HCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
FIFLGPTGVGKTELARALAESMFGDDDAMIRVDMSEFMEKHAVSRLVGAPPGYVGHDDGG
EEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCH
QLTEKVRRKPYSVILFDEIEKAHPDVFNILLQVLDDGHLTDTKGRTVDFRNTIIIMTSNV
HHHHHHHHCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCEECCCCCEEEECCEEEEEECCC
GAQELQDQRFAGFGGSSDGQDYETIRKTMLKELKNSFRPEFLNRVDDIIVFHKLTKEELK
CHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
EIVTMMVNKLTNRLSEQNINIIVTDKAKDKIAEEGYDPEYGARPLIRAIQKTIEDNLSEL
HHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
ILDGNQIEGKKVTVDHDGKEFKYDIAEQTSETKTPSQA
HHCCCCCCCCEEEECCCCCHHEEEHHHHCCCCCCCCCC
>Mature Secondary Structure
MLFGRLTERAQRVLAHAQEEAIRLNHSNIGTEHLLLGLMKEPEGIAAKVLESFNITEDKV
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCHHHH
IEEVEKLIGHGQDHVGTLHYTPRAKKVIELSMDEARKLHHNFVGTEHILLGLIRENEGVA
HHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCE
ARVFANLDLNITKARAQVVKALGNPEMSNKNAQASKSNNTPTLDSLARDLTVIAKDGTLD
EEEEECCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHEEEECCCCCC
PVIGRDKEITRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQAIVNNEVPETLKDKRVM
CCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCHHHHHCEEE
SLDMGTVVAGTKYRGEFEERLKKVMEEIQQAGNVILFIDELHTLVGAGGAEGAIDASNIL
EECCCCEEECCCCCCHHHHHHHHHHHHHHHHCCEEEEHHHHHHHHCCCCCCCCCCHHHHH
KPALARGELQCIGATTLDEYRKNIEKDAALERRFQPVQVDEPSVVDTVAILKGLRDRYEA
HHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHH
HHRINISDEAIEAAVKLSNRYVSDRFLPDKAIDLIDEASSKVRLKSHTTPNNLKEIEQEI
HCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHH
EKVKNEKDAAVHAQEFENAANLRDKQTKLEKQYEEAKNEWKNTQNGMSTSLSEEDIAEVI
HHHCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
AGWTGIPLTKINETESEKLLSLEDTLHERVIGQKDAVNSISKAVRRARAGLKDPKRPIGS
HCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
FIFLGPTGVGKTELARALAESMFGDDDAMIRVDMSEFMEKHAVSRLVGAPPGYVGHDDGG
EEEECCCCCCHHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCCCCCH
QLTEKVRRKPYSVILFDEIEKAHPDVFNILLQVLDDGHLTDTKGRTVDFRNTIIIMTSNV
HHHHHHHHCCCEEEEEHHHHHHCCHHHHHHHHHHCCCCEECCCCCEEEECCEEEEEECCC
GAQELQDQRFAGFGGSSDGQDYETIRKTMLKELKNSFRPEFLNRVDDIIVFHKLTKEELK
CHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
EIVTMMVNKLTNRLSEQNINIIVTDKAKDKIAEEGYDPEYGARPLIRAIQKTIEDNLSEL
HHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHH
ILDGNQIEGKKVTVDHDGKEFKYDIAEQTSETKTPSQA
HHCCCCCCCCEEEECCCCCHHEEEHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA