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The map label for this gene is msrB [H]

Identifier: 82703229

GI number: 82703229

Start: 2407955

End: 2408365

Strand: Direct

Name: msrB [H]

Synonym: Nmul_A2110

Alternate gene names: 82703229

Gene position: 2407955-2408365 (Clockwise)

Preceding gene: 82703228

Following gene: 82703230

Centisome position: 75.62

GC content: 54.26

Gene sequence:

>411_bases
ATGAACGACAAGCTTGTTAAATCCGACCAGGAATGGAAAAACCAGCTGACCCCGCAGCAGTATCATGTATGCCGCGAAAA
AGGGACGGAGCGGGCATTCACAGGGGAATACTGGAACTGCCACGATCAGGGGGTGTATCGTTGCGCTTGCTGCGGCGCCG
CCTTGTTTGACTCGGATACCAAATTCGATTCCGGTACGGGATGGCCTTCTTTCTGGCAGCCTACACGATCGGAAAATGTC
GTCAATCAGGAAGATAACAGTCATTTCATGCGCCGGGTAGAAGTGTTGTGCGCCCGCTGCGACGCGCACCTCGGTCACGT
ATTCGAGGACGGTCCTGCTCCGACGGGGCTGCGCTACTGCATCAATTCTGCTTCCCTCAAGCTCGATCGAGATTCTTCGA
AGACTGAATAA

Upstream 100 bases:

>100_bases
TGCAGAATTCCCGGAAGAAGGTGAAGTGGCCCCCATACACCTGCATTGAGAGTGTTCATCATCTTATTCAGGAGCATCAA
TTTTTTCCGGAAGAGGAATT

Downstream 100 bases:

>100_bases
ACGGGCAGCAAGGGAAGTTGAATGGGACGCAATGCGCTTTGCCAATTGTGCCTTGCACTCCTAAATAGCTGGGCCCGCTC
AAGCTCCTGGAAATTCATCA

Product: protein-methionine-S-oxide reductase

Products: NA

Alternate protein names: Peptide-methionine (R)-S-oxide reductase [H]

Number of amino acids: Translated: 136; Mature: 136

Protein sequence:

>136_residues
MNDKLVKSDQEWKNQLTPQQYHVCREKGTERAFTGEYWNCHDQGVYRCACCGAALFDSDTKFDSGTGWPSFWQPTRSENV
VNQEDNSHFMRRVEVLCARCDAHLGHVFEDGPAPTGLRYCINSASLKLDRDSSKTE

Sequences:

>Translated_136_residues
MNDKLVKSDQEWKNQLTPQQYHVCREKGTERAFTGEYWNCHDQGVYRCACCGAALFDSDTKFDSGTGWPSFWQPTRSENV
VNQEDNSHFMRRVEVLCARCDAHLGHVFEDGPAPTGLRYCINSASLKLDRDSSKTE
>Mature_136_residues
MNDKLVKSDQEWKNQLTPQQYHVCREKGTERAFTGEYWNCHDQGVYRCACCGAALFDSDTKFDSGTGWPSFWQPTRSENV
VNQEDNSHFMRRVEVLCARCDAHLGHVFEDGPAPTGLRYCINSASLKLDRDSSKTE

Specific function: Unknown

COG id: COG0229

COG function: function code O; Conserved domain frequently associated with peptide methionine sulfoxide reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the msrB Met sulfoxide reductase family [H]

Homologues:

Organism=Homo sapiens, GI301336164, Length=135, Percent_Identity=57.037037037037, Blast_Score=159, Evalue=1e-39,
Organism=Homo sapiens, GI301336162, Length=135, Percent_Identity=57.037037037037, Blast_Score=159, Evalue=1e-39,
Organism=Homo sapiens, GI73089054, Length=135, Percent_Identity=57.037037037037, Blast_Score=159, Evalue=1e-39,
Organism=Homo sapiens, GI37620216, Length=135, Percent_Identity=57.037037037037, Blast_Score=158, Evalue=1e-39,
Organism=Homo sapiens, GI117606353, Length=132, Percent_Identity=46.2121212121212, Blast_Score=130, Evalue=2e-31,
Organism=Homo sapiens, GI7706511, Length=105, Percent_Identity=35.2380952380952, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1788077, Length=121, Percent_Identity=52.0661157024793, Blast_Score=137, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17553450, Length=131, Percent_Identity=48.8549618320611, Blast_Score=118, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI115532676, Length=131, Percent_Identity=48.8549618320611, Blast_Score=118, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6319816, Length=130, Percent_Identity=43.8461538461538, Blast_Score=113, Evalue=9e-27,
Organism=Drosophila melanogaster, GI24645799, Length=128, Percent_Identity=50.78125, Blast_Score=131, Evalue=2e-31,
Organism=Drosophila melanogaster, GI45553335, Length=128, Percent_Identity=50.78125, Blast_Score=130, Evalue=2e-31,
Organism=Drosophila melanogaster, GI21356369, Length=128, Percent_Identity=50.78125, Blast_Score=130, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24645801, Length=139, Percent_Identity=47.4820143884892, Blast_Score=126, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24645804, Length=139, Percent_Identity=47.4820143884892, Blast_Score=125, Evalue=6e-30,
Organism=Drosophila melanogaster, GI221378664, Length=136, Percent_Identity=44.8529411764706, Blast_Score=124, Evalue=1e-29,
Organism=Drosophila melanogaster, GI221378662, Length=143, Percent_Identity=42.6573426573427, Blast_Score=122, Evalue=8e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002579
- InterPro:   IPR011057 [H]

Pfam domain/function: PF01641 SelR [H]

EC number: =1.8.4.12 [H]

Molecular weight: Translated: 15557; Mature: 15557

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
5.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDKLVKSDQEWKNQLTPQQYHVCREKGTERAFTGEYWNCHDQGVYRCACCGAALFDSDT
CCCCCCCCCHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
KFDSGTGWPSFWQPTRSENVVNQEDNSHFMRRVEVLCARCDAHLGHVFEDGPAPTGLRYC
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCHHHHH
INSASLKLDRDSSKTE
HCCCCEEECCCCCCCC
>Mature Secondary Structure
MNDKLVKSDQEWKNQLTPQQYHVCREKGTERAFTGEYWNCHDQGVYRCACCGAALFDSDT
CCCCCCCCCHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
KFDSGTGWPSFWQPTRSENVVNQEDNSHFMRRVEVLCARCDAHLGHVFEDGPAPTGLRYC
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHCCCCCCCHHHHH
INSASLKLDRDSSKTE
HCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12240834 [H]