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The map label for this gene is qor [H]

Identifier: 82703080

GI number: 82703080

Start: 2252646

End: 2253647

Strand: Direct

Name: qor [H]

Synonym: Nmul_A1959

Alternate gene names: 82703080

Gene position: 2252646-2253647 (Clockwise)

Preceding gene: 82703078

Following gene: 162139863

Centisome position: 70.74

GC content: 55.09

Gene sequence:

>1002_bases
ATGAAAGCGATACTGATGAATGCTCCGGGTGCACCAGAGGTGTTGACACCTGCCGACGTTCCCATGCCCGATCTTGCCGG
CGCATTTGATGTGCGGGTAAAGTTGCACGCGGCGGGCGTAAACCCGATCGATACCAAGGTGCGCAAGGCCAATATGTATT
ACCCGGACAGGCTTCCGTCCATTCTCGGATGTGATGGGGCGGGTGTGGTTGAAGCCGTTGGCAGTTCAGTGACCCGGGTA
CGCGCAGGCGATGAAGTCTTCTTTTTCAATAACGGTTTGGGCGGAGCGCCCGGAAACTATGCGGAATATGCGGTAGTGCA
TGAAGATTATCTGGCATTGAAACCTGGGAATCTGTCAATGGTGGAAGCAGCCGCTGTTCCGTTGGCTCTGATTACCGCCT
GGGAAGCACTGATAAAGCGTGGCAATCTCAAGGGGAGCCAGATTGCGCTGATTCATGCCGGCGCGGGTGGCGTGGGTCAT
ATTGCCATCCAGCTTGCCCGATACCTGAAGGCCCGGGTTGCAACGACAATTTCGAGCGAGGAAAAGGCTGCCTTCGTGCA
ATCCCTGGGAGCCGAGCTTGCAATCGATTATCGCGAAAATGACTTTGTGGACACTGCGCTCGAATGGACGGAGGGACTGG
GTGTGAACCTCGCTCTGGATACTGTCGGTGGAGAGACGTTCTGCAAATCCTTCTCCGCCATCCGGCTGTATGGCAGGGTG
GTATCGCTGCTTTCAACGGTCTGTGATGCAAAGCAGCTCAATACTGCCCGACTGCGCAACCTGAGCATCGGCTATGTGCA
AATGACTGCTCCCCTTTATTTCGGTTTACATTCGGCGCGTGTAGTCCAAACCGGCATACTTGAACAAGGTGCAAGACTGC
TCGAACAAGGTATTCTCAAGATTCACGTCAGCCGCACGCTGCCTCTGACGGAAGCCGCCGAAGCGCATCGTTTGATCGAA
GCGGGGCATACTCTGGGCAAGATAGTGCTGAAGATTGTGTAG

Upstream 100 bases:

>100_bases
TACCGTCCTCCGCTACGCCTTTCATTCCTGTTCCACTCGTAGCCGAGGATCGCACGCGTATTGTTGATCAGCCATCCAGA
AAGAAGAATAAAGGGAAATC

Downstream 100 bases:

>100_bases
CGGTTTCATTCTTCAAGGTATTCCGCCGGCTGCGTGAGGTTGGGCTTTCAAGAAGAATCGTGGATTTCCAGCGTTCCTCC
CGTTTTCAGCTTTTTCCCTC

Product: zinc-containing alcohol dehydrogenase superfamily protein

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MKAILMNAPGAPEVLTPADVPMPDLAGAFDVRVKLHAAGVNPIDTKVRKANMYYPDRLPSILGCDGAGVVEAVGSSVTRV
RAGDEVFFFNNGLGGAPGNYAEYAVVHEDYLALKPGNLSMVEAAAVPLALITAWEALIKRGNLKGSQIALIHAGAGGVGH
IAIQLARYLKARVATTISSEEKAAFVQSLGAELAIDYRENDFVDTALEWTEGLGVNLALDTVGGETFCKSFSAIRLYGRV
VSLLSTVCDAKQLNTARLRNLSIGYVQMTAPLYFGLHSARVVQTGILEQGARLLEQGILKIHVSRTLPLTEAAEAHRLIE
AGHTLGKIVLKIV

Sequences:

>Translated_333_residues
MKAILMNAPGAPEVLTPADVPMPDLAGAFDVRVKLHAAGVNPIDTKVRKANMYYPDRLPSILGCDGAGVVEAVGSSVTRV
RAGDEVFFFNNGLGGAPGNYAEYAVVHEDYLALKPGNLSMVEAAAVPLALITAWEALIKRGNLKGSQIALIHAGAGGVGH
IAIQLARYLKARVATTISSEEKAAFVQSLGAELAIDYRENDFVDTALEWTEGLGVNLALDTVGGETFCKSFSAIRLYGRV
VSLLSTVCDAKQLNTARLRNLSIGYVQMTAPLYFGLHSARVVQTGILEQGARLLEQGILKIHVSRTLPLTEAAEAHRLIE
AGHTLGKIVLKIV
>Mature_333_residues
MKAILMNAPGAPEVLTPADVPMPDLAGAFDVRVKLHAAGVNPIDTKVRKANMYYPDRLPSILGCDGAGVVEAVGSSVTRV
RAGDEVFFFNNGLGGAPGNYAEYAVVHEDYLALKPGNLSMVEAAAVPLALITAWEALIKRGNLKGSQIALIHAGAGGVGH
IAIQLARYLKARVATTISSEEKAAFVQSLGAELAIDYRENDFVDTALEWTEGLGVNLALDTVGGETFCKSFSAIRLYGRV
VSLLSTVCDAKQLNTARLRNLSIGYVQMTAPLYFGLHSARVVQTGILEQGARLLEQGILKIHVSRTLPLTEAAEAHRLIE
AGHTLGKIVLKIV

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI22538446, Length=346, Percent_Identity=31.7919075144509, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI22538444, Length=346, Percent_Identity=31.7919075144509, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI194239674, Length=333, Percent_Identity=29.1291291291291, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI13236495, Length=333, Percent_Identity=29.1291291291291, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI47519420, Length=373, Percent_Identity=29.7587131367292, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI194239676, Length=332, Percent_Identity=29.2168674698795, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI18379349, Length=314, Percent_Identity=28.343949044586, Blast_Score=108, Evalue=9e-24,
Organism=Homo sapiens, GI28557745, Length=229, Percent_Identity=33.1877729257642, Blast_Score=92, Evalue=9e-19,
Organism=Homo sapiens, GI24308257, Length=352, Percent_Identity=25.5681818181818, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI41872631, Length=239, Percent_Identity=28.8702928870293, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI67078404, Length=201, Percent_Identity=30.8457711442786, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI90669511, Length=245, Percent_Identity=29.7959183673469, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI67078406, Length=194, Percent_Identity=29.3814432989691, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1790485, Length=337, Percent_Identity=33.5311572700297, Blast_Score=140, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI17507255, Length=256, Percent_Identity=30.859375, Blast_Score=103, Evalue=9e-23,
Organism=Caenorhabditis elegans, GI71987554, Length=355, Percent_Identity=27.887323943662, Blast_Score=88, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI212642053, Length=240, Percent_Identity=31.6666666666667, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17556000, Length=262, Percent_Identity=24.8091603053435, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=336, Percent_Identity=28.8690476190476, Blast_Score=109, Evalue=6e-25,
Organism=Drosophila melanogaster, GI221330659, Length=227, Percent_Identity=28.6343612334802, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19920632, Length=227, Percent_Identity=28.6343612334802, Blast_Score=73, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24581345, Length=227, Percent_Identity=29.0748898678414, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24581339, Length=343, Percent_Identity=26.8221574344023, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24581341, Length=343, Percent_Identity=26.8221574344023, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 35395; Mature: 35395

Theoretical pI: Translated: 7.25; Mature: 7.25

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAILMNAPGAPEVLTPADVPMPDLAGAFDVRVKLHAAGVNPIDTKVRKANMYYPDRLPS
CCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHCCCCCCCCCCCH
ILGCDGAGVVEAVGSSVTRVRAGDEVFFFNNGLGGAPGNYAEYAVVHEDYLALKPGNLSM
HHCCCCCHHHHHHCCHHEEEECCCEEEEEECCCCCCCCCCCEEEEEECCEEEECCCCCCH
VEAAAVPLALITAWEALIKRGNLKGSQIALIHAGAGGVGHIAIQLARYLKARVATTISSE
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCH
EKAAFVQSLGAELAIDYRENDFVDTALEWTEGLGVNLALDTVGGETFCKSFSAIRLYGRV
HHHHHHHHCCCCEEEECCCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHH
VSLLSTVCDAKQLNTARLRNLSIGYVQMTAPLYFGLHSARVVQTGILEQGARLLEQGILK
HHHHHHHHHHHHCCHHHHHCCEEEEEEEECHHHHCCHHHHHHHHHHHHHHHHHHHCCCEE
IHVSRTLPLTEAAEAHRLIEAGHTLGKIVLKIV
EEEECCCCCHHHHHHHHHHHHCCHHHHHHHHCC
>Mature Secondary Structure
MKAILMNAPGAPEVLTPADVPMPDLAGAFDVRVKLHAAGVNPIDTKVRKANMYYPDRLPS
CCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHCCCCCCCCCCCH
ILGCDGAGVVEAVGSSVTRVRAGDEVFFFNNGLGGAPGNYAEYAVVHEDYLALKPGNLSM
HHCCCCCHHHHHHCCHHEEEECCCEEEEEECCCCCCCCCCCEEEEEECCEEEECCCCCCH
VEAAAVPLALITAWEALIKRGNLKGSQIALIHAGAGGVGHIAIQLARYLKARVATTISSE
HHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCH
EKAAFVQSLGAELAIDYRENDFVDTALEWTEGLGVNLALDTVGGETFCKSFSAIRLYGRV
HHHHHHHHCCCCEEEECCCCCHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHH
VSLLSTVCDAKQLNTARLRNLSIGYVQMTAPLYFGLHSARVVQTGILEQGARLLEQGILK
HHHHHHHHHHHHCCHHHHHCCEEEEEEEECHHHHCCHHHHHHHHHHHHHHHHHHHCCCEE
IHVSRTLPLTEAAEAHRLIEAGHTLGKIVLKIV
EEEECCCCCHHHHHHHHHHHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]