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The map label for this gene is dapD

Identifier: 82702972

GI number: 82702972

Start: 2134905

End: 2135726

Strand: Direct

Name: dapD

Synonym: Nmul_A1851

Alternate gene names: 82702972

Gene position: 2134905-2135726 (Clockwise)

Preceding gene: 82702971

Following gene: 82702973

Centisome position: 67.05

GC content: 53.65

Gene sequence:

>822_bases
ATGGATCAGCTCCAAAGTACGATTGAAGAAGCGTTTGAACGCCGCGCCGAGATGACCCCGCGTAACGTCGAAGCGAAGCT
CAAGGAATCCATTACCCAGGTACTGGAAATGCTCGACAGCGGCAAACTGCGGGTGGCGGAAAAAACAGACGGCGAATGGA
AAACCCATCAATGGATAAAAAAAGCGGTGCTGTTGTCGTTCCGCATCGAGGACAACAGCTTCATCAAGGGTGGATTTTCC
AATTATTTCGACAAAGTACCTTCCAAGTTCGCAGATTACAGCTCCCGCGATTTTCGTAATGGCGGTTTCCGCGTCGTGCC
TCCCGCAACCGTACGCAAAGGCGCTTTCATTGCCAGCAATGTCGTACTGATGCCCTCCTACGTCAATATCGGCGCATACG
TAGATGAAGGGACCATGGTCGACACCTGGGCTACAGTGGGTTCCTGCGCCCAGATCGGAAAAAACGTGCATCTATCCGGT
GGGGTCGGAATCGGCGGGGTGCTCGAGCCCGTGCAGGCCAATCCTACCATCATCGAGGACAACTGCTTCATCGGCGCGCG
TTCGGAAGTCGTGGAAGGCGTGATTGTCGGTGAAAACTCCGTGATTTCCATGGGGGTATACATCGGTCAGAGCACCCGGA
TTTATAACCGCGAAACAGGTGAAATCAGCTATGGCCGTATCCCTCCCGGTTCCGTCGTCGTTTCCGGCAGCCTGCCTTCC
GCAGATGGCAAATACAGCCTCTATTGCGCAGTCATCGTGAAACAGGTGGACGCCAAGACCCGAGCTAAAACCGGTATCAA
TGAGCTGTTAAGGGGAATTTAA

Upstream 100 bases:

>100_bases
GGAATGCGCCGCCGCTACCGAACGGATAAAGAAGCTGGTATCCAGATTGTAGCGGGTAGCCTGGAGCAGCGATATATCAA
CAAGAAATCAAAGGAAGATC

Downstream 100 bases:

>100_bases
CATCCGGAATTTAACACCGACTTTCATCCACAACAGGCTTCTTTTCAGGAATTGCTCATGCTCAATGACACACTGGCGCT
CGCGCAAATGTTGATCGCCC

Product: 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase

Products: NA

Alternate protein names: Tetrahydrodipicolinate N-succinyltransferase; THDP succinyltransferase; THP succinyltransferase; Tetrahydropicolinate succinylase

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MDQLQSTIEEAFERRAEMTPRNVEAKLKESITQVLEMLDSGKLRVAEKTDGEWKTHQWIKKAVLLSFRIEDNSFIKGGFS
NYFDKVPSKFADYSSRDFRNGGFRVVPPATVRKGAFIASNVVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSG
GVGIGGVLEPVQANPTIIEDNCFIGARSEVVEGVIVGENSVISMGVYIGQSTRIYNRETGEISYGRIPPGSVVVSGSLPS
ADGKYSLYCAVIVKQVDAKTRAKTGINELLRGI

Sequences:

>Translated_273_residues
MDQLQSTIEEAFERRAEMTPRNVEAKLKESITQVLEMLDSGKLRVAEKTDGEWKTHQWIKKAVLLSFRIEDNSFIKGGFS
NYFDKVPSKFADYSSRDFRNGGFRVVPPATVRKGAFIASNVVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSG
GVGIGGVLEPVQANPTIIEDNCFIGARSEVVEGVIVGENSVISMGVYIGQSTRIYNRETGEISYGRIPPGSVVVSGSLPS
ADGKYSLYCAVIVKQVDAKTRAKTGINELLRGI
>Mature_273_residues
MDQLQSTIEEAFERRAEMTPRNVEAKLKESITQVLEMLDSGKLRVAEKTDGEWKTHQWIKKAVLLSFRIEDNSFIKGGFS
NYFDKVPSKFADYSSRDFRNGGFRVVPPATVRKGAFIASNVVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSG
GVGIGGVLEPVQANPTIIEDNCFIGARSEVVEGVIVGENSVISMGVYIGQSTRIYNRETGEISYGRIPPGSVVVSGSLPS
ADGKYSLYCAVIVKQVDAKTRAKTGINELLRGI

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; fourth step. [C]

COG id: COG2171

COG function: function code E; Tetrahydrodipicolinate N-succinyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family

Homologues:

Organism=Escherichia coli, GI1786362, Length=273, Percent_Identity=79.8534798534799, Blast_Score=432, Evalue=1e-123,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): DAPD_NITMU (Q2Y7X5)

Other databases:

- EMBL:   CP000103
- RefSeq:   YP_412538.1
- ProteinModelPortal:   Q2Y7X5
- SMR:   Q2Y7X5
- STRING:   Q2Y7X5
- GeneID:   3786593
- GenomeReviews:   CP000103_GR
- KEGG:   nmu:Nmul_A1851
- eggNOG:   COG2171
- HOGENOM:   HBG704071
- OMA:   QWAKKAV
- PhylomeDB:   Q2Y7X5
- ProtClustDB:   PRK11830
- BioCyc:   NMUL323848:NMUL_A1851-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00811
- InterPro:   IPR005664
- InterPro:   IPR018357
- InterPro:   IPR023180
- InterPro:   IPR011004
- Gene3D:   G3DSA:1.10.166.10
- TIGRFAMs:   TIGR00965

Pfam domain/function: SSF51161 Trimer_LpxA_like

EC number: =2.3.1.117

Molecular weight: Translated: 29711; Mature: 29711

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: BINDING 104-104 BINDING 141-141

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQLQSTIEEAFERRAEMTPRNVEAKLKESITQVLEMLDSGKLRVAEKTDGEWKTHQWIK
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHH
KAVLLSFRIEDNSFIKGGFSNYFDKVPSKFADYSSRDFRNGGFRVVPPATVRKGAFIASN
HHHHEEEEECCCCEEECCHHHHHHHHHHHHHCCCCCCCCCCCEEEECCHHHHCCCEEECC
VVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPVQANPTIIED
EEEECCEEECCEEECCCCEEEHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCEEEC
NCFIGARSEVVEGVIVGENSVISMGVYIGQSTRIYNRETGEISYGRIPPGSVVVSGSLPS
CCEECCHHHHHCEEEECCCCEEEEEEEECCCEEEECCCCCCEEECCCCCCCEEEECCCCC
ADGKYSLYCAVIVKQVDAKTRAKTGINELLRGI
CCCCEEEEHHHHHHHHHHHHHHHCCHHHHHHCC
>Mature Secondary Structure
MDQLQSTIEEAFERRAEMTPRNVEAKLKESITQVLEMLDSGKLRVAEKTDGEWKTHQWIK
CCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHH
KAVLLSFRIEDNSFIKGGFSNYFDKVPSKFADYSSRDFRNGGFRVVPPATVRKGAFIASN
HHHHEEEEECCCCEEECCHHHHHHHHHHHHHCCCCCCCCCCCEEEECCHHHHCCCEEECC
VVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPVQANPTIIED
EEEECCEEECCEEECCCCEEEHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCEEEC
NCFIGARSEVVEGVIVGENSVISMGVYIGQSTRIYNRETGEISYGRIPPGSVVVSGSLPS
CCEECCHHHHHCEEEECCCCEEEEEEEECCCEEEECCCCCCEEECCCCCCCEEEECCCCC
ADGKYSLYCAVIVKQVDAKTRAKTGINELLRGI
CCCCEEEEHHHHHHHHHHHHHHHCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA