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The map label for this gene is gmhB [H]

Identifier: 82702916

GI number: 82702916

Start: 2045026

End: 2045634

Strand: Reverse

Name: gmhB [H]

Synonym: Nmul_A1793

Alternate gene names: 82702916

Gene position: 2045634-2045026 (Counterclockwise)

Preceding gene: 82702917

Following gene: 82702915

Centisome position: 64.24

GC content: 53.86

Gene sequence:

>609_bases
GTGGCCGTAGTGGCTAAGAAAACTGAAGAAACTGCACCTGGAAAGGCCGTGTTTATCGACAAGGACGGCACACTTGTTCA
CGACGTGCCCTACAACGTCGATCCGCGCTATATCCGGTTGACCGTGGGTGCGGGTCCAGCTCTCCGGAATATGAAAAATG
CGGGTTATAAATTGGTCGTCATTTCCAATCAATCCGGGATCGCCCGGGGCTTGTTCGAGGAAAAGGATTTGTTTCCTGTT
AACCGCTGCATCCAGTCCTTGCTCGCGCAATATGATGTTTCCATCGACGCTTTTTATTACTGCCCGCACGCGCCGGGCGA
TGGTTGCCGATGCCGTAAGCCGATGCCGGGAATGATTTTAAAGGCTGCCAAAGATCAGGGCGTGCACCTGCAGGCCTCCT
GGATGATCGGCGATATCCTGAACGACGTGGAAGCGGGAAATCGTGCGGGTTGCCGCACGATTCATCTGGATAACGGTAAC
GAGACGGAGTGGGTAAAGGGCAATGATCGAGAACCTGTGTATTCGGTAACGGATTGGATGGAAGCAGCGGAAATTATTTG
TCAGGGTGCCAATTGCGGTGCCGTGCGCACGGAGGTTGCACACTGCTGA

Upstream 100 bases:

>100_bases
AGGATCCAAAAAACGTGGCGGACACCGTGCACTTTGTCCTGACACAACCCGACGAAACGGTGATTCCCGAAGTTATGGTT
CTCCCGATGCGGGAGACATC

Downstream 100 bases:

>100_bases
TACTGGCAGTTTTCCCGATTGCTCCCTGGAATTTGCTTTGACCCCGTATAGCTTGCAGGGCGACATATTCCAGGTAAAAG
GAGGCAGCATGAACAGCAGT

Product: HAD family hydrolase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 202; Mature: 201

Protein sequence:

>202_residues
MAVVAKKTEETAPGKAVFIDKDGTLVHDVPYNVDPRYIRLTVGAGPALRNMKNAGYKLVVISNQSGIARGLFEEKDLFPV
NRCIQSLLAQYDVSIDAFYYCPHAPGDGCRCRKPMPGMILKAAKDQGVHLQASWMIGDILNDVEAGNRAGCRTIHLDNGN
ETEWVKGNDREPVYSVTDWMEAAEIICQGANCGAVRTEVAHC

Sequences:

>Translated_202_residues
MAVVAKKTEETAPGKAVFIDKDGTLVHDVPYNVDPRYIRLTVGAGPALRNMKNAGYKLVVISNQSGIARGLFEEKDLFPV
NRCIQSLLAQYDVSIDAFYYCPHAPGDGCRCRKPMPGMILKAAKDQGVHLQASWMIGDILNDVEAGNRAGCRTIHLDNGN
ETEWVKGNDREPVYSVTDWMEAAEIICQGANCGAVRTEVAHC
>Mature_201_residues
AVVAKKTEETAPGKAVFIDKDGTLVHDVPYNVDPRYIRLTVGAGPALRNMKNAGYKLVVISNQSGIARGLFEEKDLFPVN
RCIQSLLAQYDVSIDAFYYCPHAPGDGCRCRKPMPGMILKAAKDQGVHLQASWMIGDILNDVEAGNRAGCRTIHLDNGNE
TEWVKGNDREPVYSVTDWMEAAEIICQGANCGAVRTEVAHC

Specific function: Converts the D-glycero-alpha-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-alpha-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=166, Percent_Identity=37.3493975903614, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI87082027, Length=147, Percent_Identity=32.6530612244898, Blast_Score=88, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543
- InterPro:   IPR013954 [H]

Pfam domain/function: PF08645 PNK3P [H]

EC number: NA

Molecular weight: Translated: 22111; Mature: 21980

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
4.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVVAKKTEETAPGKAVFIDKDGTLVHDVPYNVDPRYIRLTVGAGPALRNMKNAGYKLVV
CCEECCCCCCCCCCCEEEEECCCCEEEECCCCCCCCEEEEEECCCHHHHHHCCCCEEEEE
ISNQSGIARGLFEEKDLFPVNRCIQSLLAQYDVSIDAFYYCPHAPGDGCRCRKPMPGMIL
EECCCCCHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCEE
KAAKDQGVHLQASWMIGDILNDVEAGNRAGCRTIHLDNGNETEWVKGNDREPVYSVTDWM
EECCCCCEEEEEHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCEECCCCCCCEEHHHHHH
EAAEIICQGANCGAVRTEVAHC
HHHHHHCCCCCCCCHHHEECCC
>Mature Secondary Structure 
AVVAKKTEETAPGKAVFIDKDGTLVHDVPYNVDPRYIRLTVGAGPALRNMKNAGYKLVV
CEECCCCCCCCCCCEEEEECCCCEEEECCCCCCCCEEEEEECCCHHHHHHCCCCEEEEE
ISNQSGIARGLFEEKDLFPVNRCIQSLLAQYDVSIDAFYYCPHAPGDGCRCRKPMPGMIL
EECCCCCHHCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCEE
KAAKDQGVHLQASWMIGDILNDVEAGNRAGCRTIHLDNGNETEWVKGNDREPVYSVTDWM
EECCCCCEEEEEHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCEECCCCCCCEEHHHHHH
EAAEIICQGANCGAVRTEVAHC
HHHHHHCCCCCCCCHHHEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11466286; 12101286 [H]