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The map label for this gene is anr [H]

Identifier: 82702896

GI number: 82702896

Start: 2026585

End: 2027376

Strand: Reverse

Name: anr [H]

Synonym: Nmul_A1773

Alternate gene names: 82702896

Gene position: 2027376-2026585 (Counterclockwise)

Preceding gene: 82702897

Following gene: 82702895

Centisome position: 63.67

GC content: 51.01

Gene sequence:

>792_bases
ATGTCAAAACACGCACTCAAGCTGATACCTTCCTCAACGGAGCACGCGGATGTACCCAATGATTGCAAGAATTGCGGGGC
GTATCACCTTTGTATGTCCCTCTGGCTCAAAACCGCCGATTCATCCCTGCTTGAGCGCGTGGTAAAAAAGAAGCAGGTAT
TCAAGCGTGGGGAAGTGCTTTACCGTATGGGCCAGCCGCTGGAGTATATCTATGTCATCCGTGGGGGATCGGTCAAAACC
TGCGTGAGCACTGAGGATGGGCAGGTTCAAGTAATGGGTTTTCATGCAGCCGGGGAACTGCTGGGACTTAATGCCATCAG
TAATCGGGAGCATAAATGCGAAGCGAGGGCAATGGGAGTGACCTCAGTATGTGAGGTTTCCGTCGAGCGTTTCGAAGAAC
TGGCCAAGAAGGATCCGGCCATTCAGTATGAGATTCTCAAAATCATGAGTGCCGAAATCCATCATGGTCAGGAATTGCTG
CTCCTGCTCGGTAAACACAATGCCGAGGAGCGGATCGCCATTTTTCTGCTCAACTTGTCCAGGCAATTTGAACAGCGGCA
TTGTTCGGCCACCGAATTCACCTTGTGCATGTCCCGCAGCGATATCGGTAATTATCTCGGTATTGCGGAAGAGACCGTCT
GCCGCATATTTGCACGGTTTCAGGACGACGGCCTCATCAGCAGTGAATACCGTAATGTCAAACTCAAGGATATCAAGCGG
CTTGAGCAGATTGCCAACCAAAGACCCCAAAGATCCTTGAGGCAAACCAACGTCGCCTCCCTTTACTTCTGA

Upstream 100 bases:

>100_bases
GGTAAGCGGCAAGTATCAGTTAACGGATTTTCCCGGAGCGGTTCTCGGCAACATCGAGCTGCCGGCATAGCCATCCAATT
TATTGCCTATAGGTCCTCAC

Downstream 100 bases:

>100_bases
AGTGAAGTAACCTTAGGCAGGGCCGACCGGGTTTTGCAGAGCGGCCCTGCCAGTTCCCCGCTCGGCGGAGATCACCTTCT
TTCCGCTTTTTGCTCATTCA

Product: Crp/FNR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MSKHALKLIPSSTEHADVPNDCKNCGAYHLCMSLWLKTADSSLLERVVKKKQVFKRGEVLYRMGQPLEYIYVIRGGSVKT
CVSTEDGQVQVMGFHAAGELLGLNAISNREHKCEARAMGVTSVCEVSVERFEELAKKDPAIQYEILKIMSAEIHHGQELL
LLLGKHNAEERIAIFLLNLSRQFEQRHCSATEFTLCMSRSDIGNYLGIAEETVCRIFARFQDDGLISSEYRNVKLKDIKR
LEQIANQRPQRSLRQTNVASLYF

Sequences:

>Translated_263_residues
MSKHALKLIPSSTEHADVPNDCKNCGAYHLCMSLWLKTADSSLLERVVKKKQVFKRGEVLYRMGQPLEYIYVIRGGSVKT
CVSTEDGQVQVMGFHAAGELLGLNAISNREHKCEARAMGVTSVCEVSVERFEELAKKDPAIQYEILKIMSAEIHHGQELL
LLLGKHNAEERIAIFLLNLSRQFEQRHCSATEFTLCMSRSDIGNYLGIAEETVCRIFARFQDDGLISSEYRNVKLKDIKR
LEQIANQRPQRSLRQTNVASLYF
>Mature_262_residues
SKHALKLIPSSTEHADVPNDCKNCGAYHLCMSLWLKTADSSLLERVVKKKQVFKRGEVLYRMGQPLEYIYVIRGGSVKTC
VSTEDGQVQVMGFHAAGELLGLNAISNREHKCEARAMGVTSVCEVSVERFEELAKKDPAIQYEILKIMSAEIHHGQELLL
LLGKHNAEERIAIFLLNLSRQFEQRHCSATEFTLCMSRSDIGNYLGIAEETVCRIFARFQDDGLISSEYRNVKLKDIKRL
EQIANQRPQRSLRQTNVASLYF

Specific function: Transcriptional activator of anaerobic gene expression [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=225, Percent_Identity=37.7777777777778, Blast_Score=188, Evalue=2e-49,
Organism=Escherichia coli, GI1789756, Length=178, Percent_Identity=26.4044943820225, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 29839; Mature: 29708

Theoretical pI: Translated: 8.16; Mature: 8.16

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKHALKLIPSSTEHADVPNDCKNCGAYHLCMSLWLKTADSSLLERVVKKKQVFKRGEVL
CCCCCEEECCCCCCCCCCCHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
YRMGQPLEYIYVIRGGSVKTCVSTEDGQVQVMGFHAAGELLGLNAISNREHKCEARAMGV
HHCCCCEEEEEEEECCCEEEEECCCCCEEEEEEEECCCHHHCCHHHCCCCHHHHHHHCCH
TSVCEVSVERFEELAKKDPAIQYEILKIMSAEIHHGQELLLLLGKHNAEERIAIFLLNLS
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEEHHH
RQFEQRHCSATEFTLCMSRSDIGNYLGIAEETVCRIFARFQDDGLISSEYRNVKLKDIKR
HHHHHHCCCCHHHHEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHH
LEQIANQRPQRSLRQTNVASLYF
HHHHHCCCHHHHHHHCCHHHCCC
>Mature Secondary Structure 
SKHALKLIPSSTEHADVPNDCKNCGAYHLCMSLWLKTADSSLLERVVKKKQVFKRGEVL
CCCCEEECCCCCCCCCCCHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
YRMGQPLEYIYVIRGGSVKTCVSTEDGQVQVMGFHAAGELLGLNAISNREHKCEARAMGV
HHCCCCEEEEEEEECCCEEEEECCCCCEEEEEEEECCCHHHCCHHHCCCCHHHHHHHCCH
TSVCEVSVERFEELAKKDPAIQYEILKIMSAEIHHGQELLLLLGKHNAEERIAIFLLNLS
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEEHHH
RQFEQRHCSATEFTLCMSRSDIGNYLGIAEETVCRIFARFQDDGLISSEYRNVKLKDIKR
HHHHHHCCCCHHHHEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCHHHHHHH
LEQIANQRPQRSLRQTNVASLYF
HHHHHCCCHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1787797; 1787798; 10984043 [H]