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The map label for this gene is bigR [H]

Identifier: 82702807

GI number: 82702807

Start: 1924883

End: 1925224

Strand: Reverse

Name: bigR [H]

Synonym: Nmul_A1683

Alternate gene names: 82702807

Gene position: 1925224-1924883 (Counterclockwise)

Preceding gene: 82702808

Following gene: 82702806

Centisome position: 60.46

GC content: 54.68

Gene sequence:

>342_bases
ATGAATAAAGTACACGATTTCCCGGACATGATCAGCATGCGCGCTGCCGCGTTAGCCGCCTGCACCATGCTCAAGATATT
GGCGAATGAAGACCGGCTTCTCATCCTGTGCCAGCTGATCAATGGTCCCAGCAGCGTTGGCGAACTGGAAAAAGATCTGG
GAATCCGTCAGCCCACCCTTTCCCAGCAGCTGACCGTACTGCGCGAGGAAGGCCTCGTCGCGACCGAGCGTAAGGGCAAG
TACATCATTTACAGCCTTGCGAATCCTGATGTGGTCAGGATTATGGAAACCCTGTACAGCATTTATTGCGGAGGCGGGGG
TAATACCCCCCACAAGAGCTGA

Upstream 100 bases:

>100_bases
GAGAAAGGCAGAGCGGGGCGTCGATCCGGGCCTGTGCAAACAGGAGATGCTCAACCGGTAGACCGTCCAGATGATTCGCG
GGCCCGGAGAAAGACCGGTA

Downstream 100 bases:

>100_bases
TTATTCACGCTGTACCCGATTGCAAACAATATGCATGGCCTACCCTGGGCCGCGGGTGGAGCAGGAACAATTGAAAGAAG
GAGGATTAAGTGATGAACGA

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 113; Mature: 113

Protein sequence:

>113_residues
MNKVHDFPDMISMRAAALAACTMLKILANEDRLLILCQLINGPSSVGELEKDLGIRQPTLSQQLTVLREEGLVATERKGK
YIIYSLANPDVVRIMETLYSIYCGGGGNTPHKS

Sequences:

>Translated_113_residues
MNKVHDFPDMISMRAAALAACTMLKILANEDRLLILCQLINGPSSVGELEKDLGIRQPTLSQQLTVLREEGLVATERKGK
YIIYSLANPDVVRIMETLYSIYCGGGGNTPHKS
>Mature_113_residues
MNKVHDFPDMISMRAAALAACTMLKILANEDRLLILCQLINGPSSVGELEKDLGIRQPTLSQQLTVLREEGLVATERKGK
YIIYSLANPDVVRIMETLYSIYCGGGGNTPHKS

Specific function: Represses an operon that comprises at least itself and blh. Binds to a palindromic AT-rich sequence spanning the -10 region of the blh promoter and blocks transcription of the operon [H]

COG id: COG0640

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH arsR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789021, Length=96, Percent_Identity=37.5, Blast_Score=70, Evalue=4e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001845
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01022 HTH_5 [H]

EC number: NA

Molecular weight: Translated: 12421; Mature: 12421

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKVHDFPDMISMRAAALAACTMLKILANEDRLLILCQLINGPSSVGELEKDLGIRQPTL
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCCH
SQQLTVLREEGLVATERKGKYIIYSLANPDVVRIMETLYSIYCGGGGNTPHKS
HHHHHHHHHCCCEEECCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MNKVHDFPDMISMRAAALAACTMLKILANEDRLLILCQLINGPSSVGELEKDLGIRQPTL
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHCCCCCCCH
SQQLTVLREEGLVATERKGKYIIYSLANPDVVRIMETLYSIYCGGGGNTPHKS
HHHHHHHHHCCCEEECCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]