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The map label for this gene is dnaQ [H]

Identifier: 82702745

GI number: 82702745

Start: 1858296

End: 1859000

Strand: Reverse

Name: dnaQ [H]

Synonym: Nmul_A1618

Alternate gene names: 82702745

Gene position: 1859000-1858296 (Counterclockwise)

Preceding gene: 82702746

Following gene: 82702741

Centisome position: 58.38

GC content: 55.74

Gene sequence:

>705_bases
ATGCGTCAGATTTTCATAGATACGGAAACGACGGGACTCGAGCCTAAACTGGGTCATCGAATTATCGAAATCGGGGCGGT
GGAGATGATGAGCCGGCGATTGACAGGTCGCCGCTTCCATCATTATCTCAACCCGGAACGCGAGATCGAGGAGGGCGCCT
TGCAGGTGCATGGGATAACCAGCGAATTTCTTCTGGACAAGCGAAAATTCGCTGACGTGGTGCATGAGTTGCTCGAGTTC
ATCGATGGCGCCGAGCTGATCATGCACAATGCAGCGTTCGACGTCGCATTCCTTGACCATGAGCTGGGGCTTGCCAACTT
GCCGGCTCTCTGCGAATGCTGCCACTCGGTGACCGATACCCTGAAAATGGCGAAAGAGCTGTTTCCCGGTAAAAGGAACA
GCCTGGATGCGTTGTGTGAGCGGTACGAGGTGGATAACTCACGGCGCGCGCTGCACGGTGCGCTGCTGGATGCGGAACTG
CTCGCGGAAGTTTATCTTGCCATGACGCGCGGGCAGGAGAGCCTGCTCATGGAACTCGAAGCACCATCTCCGCTTGATCT
CGATATCAGCCTGCATGATTTGCAACTGGTCGTCCTGCCTGCCAGTGCCGAAGAACTGGAAGCGCACGCCCGTCAACTGG
AAATGATCGAAAAGGAAAGCAAGGGTAAATGCCTGTGGATGCGGCTCGATCCGGCAGAAGTGTAG

Upstream 100 bases:

>100_bases
ATCTTCTGAAAGTCATTCAACCGGGAGTGATTTTCTGTAAGACAAAGAGGGAAGAGTTAAACCGGAGTAATTATCCGCAA
TACAAGAGAAGGGCTGGTTG

Downstream 100 bases:

>100_bases
GGCCCTGATTCAAGGCAACCGTGGCTACGGCGAAACAAAAAGGAAATAAACCGGATTCGGGAAGCAAGTCAGTTCTGCCG
AACGATAAACGGATCGTCAG

Product: DNA polymerase III subunit epsilon

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MRQIFIDTETTGLEPKLGHRIIEIGAVEMMSRRLTGRRFHHYLNPEREIEEGALQVHGITSEFLLDKRKFADVVHELLEF
IDGAELIMHNAAFDVAFLDHELGLANLPALCECCHSVTDTLKMAKELFPGKRNSLDALCERYEVDNSRRALHGALLDAEL
LAEVYLAMTRGQESLLMELEAPSPLDLDISLHDLQLVVLPASAEELEAHARQLEMIEKESKGKCLWMRLDPAEV

Sequences:

>Translated_234_residues
MRQIFIDTETTGLEPKLGHRIIEIGAVEMMSRRLTGRRFHHYLNPEREIEEGALQVHGITSEFLLDKRKFADVVHELLEF
IDGAELIMHNAAFDVAFLDHELGLANLPALCECCHSVTDTLKMAKELFPGKRNSLDALCERYEVDNSRRALHGALLDAEL
LAEVYLAMTRGQESLLMELEAPSPLDLDISLHDLQLVVLPASAEELEAHARQLEMIEKESKGKCLWMRLDPAEV
>Mature_234_residues
MRQIFIDTETTGLEPKLGHRIIEIGAVEMMSRRLTGRRFHHYLNPEREIEEGALQVHGITSEFLLDKRKFADVVHELLEF
IDGAELIMHNAAFDVAFLDHELGLANLPALCECCHSVTDTLKMAKELFPGKRNSLDALCERYEVDNSRRALHGALLDAEL
LAEVYLAMTRGQESLLMELEAPSPLDLDISLHDLQLVVLPASAEELEAHARQLEMIEKESKGKCLWMRLDPAEV

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=237, Percent_Identity=51.0548523206751, Blast_Score=235, Evalue=2e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 26480; Mature: 26480

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRQIFIDTETTGLEPKLGHRIIEIGAVEMMSRRLTGRRFHHYLNPEREIEEGALQVHGIT
CCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCEEEECCH
SEFLLDKRKFADVVHELLEFIDGAELIMHNAAFDVAFLDHELGLANLPALCECCHSVTDT
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHEEEHHCCCCCCCCHHHHHHHHHHHHH
LKMAKELFPGKRNSLDALCERYEVDNSRRALHGALLDAELLAEVYLAMTRGQESLLMELE
HHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEEC
APSPLDLDISLHDLQLVVLPASAEELEAHARQLEMIEKESKGKCLWMRLDPAEV
CCCCCEEEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCC
>Mature Secondary Structure
MRQIFIDTETTGLEPKLGHRIIEIGAVEMMSRRLTGRRFHHYLNPEREIEEGALQVHGIT
CCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCEEEECCH
SEFLLDKRKFADVVHELLEFIDGAELIMHNAAFDVAFLDHELGLANLPALCECCHSVTDT
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHEEEHHCCCCCCCCHHHHHHHHHHHHH
LKMAKELFPGKRNSLDALCERYEVDNSRRALHGALLDAELLAEVYLAMTRGQESLLMELE
HHHHHHHCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEEC
APSPLDLDISLHDLQLVVLPASAEELEAHARQLEMIEKESKGKCLWMRLDPAEV
CCCCCEEEEEEEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3023634; 6316347; 3540531; 9278503; 1575709 [H]