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The map label for this gene is yfbQ [H]

Identifier: 82702681

GI number: 82702681

Start: 1778738

End: 1779967

Strand: Reverse

Name: yfbQ [H]

Synonym: Nmul_A1552

Alternate gene names: 82702681

Gene position: 1779967-1778738 (Counterclockwise)

Preceding gene: 82702684

Following gene: 229137830

Centisome position: 55.9

GC content: 53.98

Gene sequence:

>1230_bases
ATGCAGCCCATTCTCAAATCCAGCAAGTTGGCCAATGTATGCTATGACATTCGCGGACCGGTGCTCGACCGGGCGCGGCA
AATGGAAGAGGAAGGGCACCGTATCATCAAGCTCAATATCGGGAATCCGGCATCATTCGGTTTCGAAGCTCCCGAAGAAA
TCCTGCAGGACGTGATGCATAACCTTTCCGCCGCATCCGGTTATTGCGACTCGAAAGGATTGTTTGCGGCACGCAAGGCC
ATCATGCATTACACGCAGGAGAAGCGCATCGAGGATGTCCGGCTGGAGGATATATACATCGGCAACGGCGTTTCCGAACT
GATCGTGATGGCGATGCAGGCGCTGCTGAATACGGGTGATGAGGTTTTGATTCCTTCACCCGATTACCCGTTGTGGACAG
CAGCGGTGGTGCTGGCAGGCGGGACTCCGCGTCATTATGTGTGTGACGAGCAATCGGGCTGGTTGCCTGATCTGGAGGAT
ATTCGCTCGAAGGTGAGCTCGAACACCCGTGCGATCGTTGTCATCAATCCGAATAATCCGACAGGTGCGCTTTATCCGGA
CGAAGTGTTGCGTGAAATCATCGAGATTGCACGTCAGCATCAACTCATCGTCTACGCCGACGAAATCTATGACAAAGTCT
TGTACGAAGATGCGACCCACACTTCGATTGCGTCCCTGGCGGATGATGTGCTGTTCGTTACATTGAACGGGTTGTCCAAG
AATTATCGTGCCGCAGGGTTTCGCTCGGGATGGGCAGTGGTCTCCGGAACAAAACACTATGCGAGCGACTATATCGCTGG
TCTGACCATGCTGGCCTCCATGCGGTTGTGTGCAAATGTTCCTTCGCAGTTTGGTATCCAAACGGCGTTGGGGGGGTATC
AAAGCATCAAGGATCTGGTCATGCCCACGGGGCGTCTTATGCGGCAACGCGATCTCGCCTGGAAAATGTTGACGGAGATC
CCGGGCGTATCGTGCTATAAGCCACGAGCAGCAATGTATCTGTTCCCCCGCCTGGACCCCGCGATCTATCCGATCGAGGA
TGACGAGCAATTTGTGCTGAATTTACTGTTGGAAGAGAAGGTGCTGCTGGTGCAGGGTAGCGGTTTCAACTGGCCATATC
CAGATCATTTCCGTGTTGTATTTCTCCCTAACAGTGACGACCTGACTGAAGCCATTAGCCGGGTTGGAAGTTTTCTGGGC
CGCTACCGCAGGCAGCACGGAACCGGGTGA

Upstream 100 bases:

>100_bases
GGGCGTTTCCGGTTACGTATTTCCATCTGAATCCGGCCTTGCAAAGCGCCGTCCCTGACCTTTGCCGTAAGGCTTTTGCC
ACCCATCCTTCCCCTATCTG

Downstream 100 bases:

>100_bases
GGCGAACTCGACTTCTGTAAACGACAACGCCGCGTACGAACAAAATCCCTTTCAGCAAATATGGCAAATATGTCCGAAAA
ATTCATCATTACCGAAGATA

Product: aminotransferase AlaT

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 409

Protein sequence:

>409_residues
MQPILKSSKLANVCYDIRGPVLDRARQMEEEGHRIIKLNIGNPASFGFEAPEEILQDVMHNLSAASGYCDSKGLFAARKA
IMHYTQEKRIEDVRLEDIYIGNGVSELIVMAMQALLNTGDEVLIPSPDYPLWTAAVVLAGGTPRHYVCDEQSGWLPDLED
IRSKVSSNTRAIVVINPNNPTGALYPDEVLREIIEIARQHQLIVYADEIYDKVLYEDATHTSIASLADDVLFVTLNGLSK
NYRAAGFRSGWAVVSGTKHYASDYIAGLTMLASMRLCANVPSQFGIQTALGGYQSIKDLVMPTGRLMRQRDLAWKMLTEI
PGVSCYKPRAAMYLFPRLDPAIYPIEDDEQFVLNLLLEEKVLLVQGSGFNWPYPDHFRVVFLPNSDDLTEAISRVGSFLG
RYRRQHGTG

Sequences:

>Translated_409_residues
MQPILKSSKLANVCYDIRGPVLDRARQMEEEGHRIIKLNIGNPASFGFEAPEEILQDVMHNLSAASGYCDSKGLFAARKA
IMHYTQEKRIEDVRLEDIYIGNGVSELIVMAMQALLNTGDEVLIPSPDYPLWTAAVVLAGGTPRHYVCDEQSGWLPDLED
IRSKVSSNTRAIVVINPNNPTGALYPDEVLREIIEIARQHQLIVYADEIYDKVLYEDATHTSIASLADDVLFVTLNGLSK
NYRAAGFRSGWAVVSGTKHYASDYIAGLTMLASMRLCANVPSQFGIQTALGGYQSIKDLVMPTGRLMRQRDLAWKMLTEI
PGVSCYKPRAAMYLFPRLDPAIYPIEDDEQFVLNLLLEEKVLLVQGSGFNWPYPDHFRVVFLPNSDDLTEAISRVGSFLG
RYRRQHGTG
>Mature_409_residues
MQPILKSSKLANVCYDIRGPVLDRARQMEEEGHRIIKLNIGNPASFGFEAPEEILQDVMHNLSAASGYCDSKGLFAARKA
IMHYTQEKRIEDVRLEDIYIGNGVSELIVMAMQALLNTGDEVLIPSPDYPLWTAAVVLAGGTPRHYVCDEQSGWLPDLED
IRSKVSSNTRAIVVINPNNPTGALYPDEVLREIIEIARQHQLIVYADEIYDKVLYEDATHTSIASLADDVLFVTLNGLSK
NYRAAGFRSGWAVVSGTKHYASDYIAGLTMLASMRLCANVPSQFGIQTALGGYQSIKDLVMPTGRLMRQRDLAWKMLTEI
PGVSCYKPRAAMYLFPRLDPAIYPIEDDEQFVLNLLLEEKVLLVQGSGFNWPYPDHFRVVFLPNSDDLTEAISRVGSFLG
RYRRQHGTG

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=404, Percent_Identity=24.5049504950495, Blast_Score=142, Evalue=8e-34,
Organism=Homo sapiens, GI19263340, Length=470, Percent_Identity=24.6808510638298, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI4885351, Length=451, Percent_Identity=25.7206208425721, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI215599424, Length=390, Percent_Identity=25.3846153846154, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI95147551, Length=236, Percent_Identity=25.8474576271186, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI169881279, Length=236, Percent_Identity=25.8474576271186, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI56713254, Length=168, Percent_Identity=26.7857142857143, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI56713256, Length=168, Percent_Identity=26.7857142857143, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI169881281, Length=147, Percent_Identity=27.891156462585, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1788627, Length=404, Percent_Identity=64.3564356435644, Blast_Score=570, Evalue=1e-164,
Organism=Escherichia coli, GI1788722, Length=375, Percent_Identity=26.6666666666667, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1786816, Length=265, Percent_Identity=25.2830188679245, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1790797, Length=366, Percent_Identity=25.4098360655738, Blast_Score=63, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17567663, Length=379, Percent_Identity=30.0791556728232, Blast_Score=173, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI71981209, Length=462, Percent_Identity=24.025974025974, Blast_Score=111, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI17567369, Length=245, Percent_Identity=28.5714285714286, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71994472, Length=166, Percent_Identity=31.3253012048193, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI71994476, Length=166, Percent_Identity=31.3253012048193, Blast_Score=89, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI71981215, Length=292, Percent_Identity=24.3150684931507, Blast_Score=82, Evalue=6e-16,
Organism=Saccharomyces cerevisiae, GI6320317, Length=473, Percent_Identity=25.7928118393235, Blast_Score=133, Evalue=5e-32,
Organism=Saccharomyces cerevisiae, GI6323118, Length=471, Percent_Identity=26.3269639065817, Blast_Score=129, Evalue=9e-31,
Organism=Saccharomyces cerevisiae, GI6322401, Length=308, Percent_Identity=24.3506493506494, Blast_Score=90, Evalue=7e-19,
Organism=Drosophila melanogaster, GI18859735, Length=377, Percent_Identity=29.973474801061, Blast_Score=177, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24641770, Length=466, Percent_Identity=25.9656652360515, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24641760, Length=466, Percent_Identity=25.9656652360515, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24641768, Length=466, Percent_Identity=25.9656652360515, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24641766, Length=466, Percent_Identity=25.9656652360515, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24641764, Length=466, Percent_Identity=25.9656652360515, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI45551451, Length=466, Percent_Identity=25.9656652360515, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI28573069, Length=243, Percent_Identity=26.3374485596708, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24646114, Length=243, Percent_Identity=26.3374485596708, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28573067, Length=243, Percent_Identity=26.3374485596708, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28573065, Length=243, Percent_Identity=26.3374485596708, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 45677; Mature: 45677

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPILKSSKLANVCYDIRGPVLDRARQMEEEGHRIIKLNIGNPASFGFEAPEEILQDVMH
CCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NLSAASGYCDSKGLFAARKAIMHYTQEKRIEDVRLEDIYIGNGVSELIVMAMQALLNTGD
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCEEEEEEECCCHHHHHHHHHHHHHCCCC
EVLIPSPDYPLWTAAVVLAGGTPRHYVCDEQSGWLPDLEDIRSKVSSNTRAIVVINPNNP
EEEECCCCCCHHHHHHHEECCCCCCEEECCCCCCCCCHHHHHHHHCCCCEEEEEEECCCC
TGALYPDEVLREIIEIARQHQLIVYADEIYDKVLYEDATHTSIASLADDVLFVTLNGLSK
CCCCCHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHCCCCHHHHHHHHCCEEEEEECCCCC
NYRAAGFRSGWAVVSGTKHYASDYIAGLTMLASMRLCANVPSQFGIQTALGGYQSIKDLV
CCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHCHHHHHCHHHHHHHHH
MPTGRLMRQRDLAWKMLTEIPGVSCYKPRAAMYLFPRLDPAIYPIEDDEQFVLNLLLEEK
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCEECCCCCHHHHHHHHHHCC
VLLVQGSGFNWPYPDHFRVVFLPNSDDLTEAISRVGSFLGRYRRQHGTG
EEEEECCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MQPILKSSKLANVCYDIRGPVLDRARQMEEEGHRIIKLNIGNPASFGFEAPEEILQDVMH
CCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
NLSAASGYCDSKGLFAARKAIMHYTQEKRIEDVRLEDIYIGNGVSELIVMAMQALLNTGD
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCEEEEEEECCCHHHHHHHHHHHHHCCCC
EVLIPSPDYPLWTAAVVLAGGTPRHYVCDEQSGWLPDLEDIRSKVSSNTRAIVVINPNNP
EEEECCCCCCHHHHHHHEECCCCCCEEECCCCCCCCCHHHHHHHHCCCCEEEEEEECCCC
TGALYPDEVLREIIEIARQHQLIVYADEIYDKVLYEDATHTSIASLADDVLFVTLNGLSK
CCCCCHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHCCCCHHHHHHHHCCEEEEEECCCCC
NYRAAGFRSGWAVVSGTKHYASDYIAGLTMLASMRLCANVPSQFGIQTALGGYQSIKDLV
CCCCCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCHHHCHHHHHCHHHHHHHHH
MPTGRLMRQRDLAWKMLTEIPGVSCYKPRAAMYLFPRLDPAIYPIEDDEQFVLNLLLEEK
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCEECCCCCHHHHHHHHHHCC
VLLVQGSGFNWPYPDHFRVVFLPNSDDLTEAISRVGSFLGRYRRQHGTG
EEEEECCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]