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The map label for this gene is arcB [H]

Identifier: 82702619

GI number: 82702619

Start: 1700803

End: 1703310

Strand: Reverse

Name: arcB [H]

Synonym: Nmul_A1490

Alternate gene names: 82702619

Gene position: 1703310-1700803 (Counterclockwise)

Preceding gene: 82702624

Following gene: 82702618

Centisome position: 53.49

GC content: 55.14

Gene sequence:

>2508_bases
ATGCTAGGCTTTGAACAGGGTTCTCCACAATGCGTAATATCAATATTGTGTCAGAAAGAGGAAGGGATGAACGAGCGGGA
AACCACAAGCTGTGCAGAACTGCCGGGGTGGCTGCAAGGCAGCGAGATGGGGGCACTGATTTTTACCCATGATTGGATCG
ATTCGAGTCTTGGGCCTATATCGGCATGGTCACCTGCTCTTCGATTCGCAGTCAACATGATATTGCTGATGCCGTCGGCC
GTCCTGTTACTGTGGGGACCAAAGCTGATACAGATCTATAATGATGGTTATCGCAATCTGATGGGCGCCAAGCATCCGGA
TGGATTGGGGCAACCTGTTTCGGAGTGTTGGCCGGAGGTATGGCATTTTCTTGCGCCCATCTGTGAGGGGGTGATGGAGC
GGCGCCAATCCTTCAGCTTTGATGATCAACCGCTTGTCATTAATCGCACCGGAAGTCCCGAAGAGGCTTTTTTCAAACTT
ACCTACAGCCCCGTTCCCGATATCAAGGACAGCTTTTCCAGGGAGGTTTCCCCAGATGCGAAGCAAACCGGAGTGTCGGG
TGTACTTGTGACGGTAACCGAGACAACAGAGCTTGTCCGGGCACGTGCTCATGAAGCGAAGAAAATCAGGTTCAAGGAGG
CCTTGGCTGAGCAGGCGCTGCGTGAGAGCGAACAGCGCTTCTGCCAGGCTCTCGAGATCGAGACTGTCGGAATCATTTTC
TTCGATAGCGAAAATCGGATTACTGAAGCGAACGATGCCTTCCTGGAGATGAGTGGCTTCAGTCGGGACGATGAGCGAGC
AGGGGCGCTGCGATGCGATGAGCTAATCCCGCCGGAGTGGCGAATGAGTACTTCCCGGGCTGCAGAGGAACTCAAGGCAA
TGGGGCGAGTGGCCCCTCATGAAAAGGAATTATTTCGCAAGGATGGGTCCCGGTGGTGGGCATTAATCGCGATGAAGCAA
CTCCTCGGCAACGAGGCGGTAGCATATGTGGTCGACATAACGGAACGCAAACGCGTCGAACATAGCCTGCGCGAGAGCGA
GGCAAGATTCCGTGCGCTGGCGGAGGCTTCCCCAGCCCTGATCTGGCAGGTGGATCCACAAGGAAATGCGGTTTATCTCA
ACCAGCGCTACCAGTACATGTTCGGGAAGAGTCTGGAAGAGCTGATGCCGACCGGATGGCGCGAGCTTCTTCATCCTGAC
GATGCCCCTGCATATGTTGCCGCGTTCGAGCGGGCGCTACATGACCGGGCGCACTTGAGACAGCGGGTCCGCGCCAGGAC
AGCCGAGGGGGAGTGGCGCTGGCTGAAATCGTATGCCTTGCCGTGGTTTACCGTCAGGGATGAGTACGCGGGGCATGTGG
GCATATCGATAGATATTACTGAAGCAGTAGCTGCAGAAACCGCTCTGCTGGAGGCCGACCGTCGGAAGGATGAGTTTCTC
GCTACGCTCGCACATGAGTTGCGTAATCCGCTCGCCCCGATTGCCAGCGCGCTGACACTCATTGCAGGCCCCGATGGAGC
AGCCGAAATACCTCGTCTGCTGCCTGTCATCAACCGGCAGGTCAACTACATGGTTCGACTGGTGGATGATCTCCTGGAGA
TATCGCGGATCACCAGCGGAAAGGTCGAATTGCGCCAGAAACCCACTGATCTGGCCATTGTCTTGCGCAATGCAGCCGAG
GCCAGCATGGAACAGATAAGGGAAAAGGAGCTCGAATTGAGCATATCCATCACCGATACGCCTTTGATTGTGTATGGCGA
CACGGTGCGTCTGGAACAGATCTTCGCGAATCTGCTCAACAATGCTGTGCGCTACACCGGGAGAGGGGGAAAGATATGGC
TTACCGCCCGCCAGGAAGATCATAAAGCTGTCGTATCCGTGAAGGACAATGGTATAGGAATATTACCGGGAATGCTGCCG
CGTTTATTCGATATGTTTGCGCAGGAGCGGCGCAGCGGCATGGGCACTCAGGAGGGACTAGGGATTGGCCTCAACCTGGT
GGACCGCCTTGTCCAGATGCACGGCGGTAGTGTCGAGGCCTCGAGTGAAGGAAAGGATAAAGGCAGTGAATTCACAGTGC
GCCTGCCTTTGTCCGAGATCACTACAAGTGGAAAAAGCGGTCAATCCGAGAAGGTGGCATTCGCCCCGCAGGAACTGCGC
GTGCTGGTGGTCGATGACAATCAGGACGCCGCGGAGGTCCTGTGTATGTTGTTGCAATCAATGGGAGTGGATGTCAAAGC
AGTAGATAGCGGGCCTGCCGCACTTGCCACGCTTCCCCATTATCTGCCTGATGTCGTTTTGATGGATATCGGTATGCCGG
GGATGGATGGTAACGAAGTGGCACGACGTATTCGGGTGCAGCCGCAATTCAACAATATAAAGCTCATCGCGCTGACCGGC
TGGGGCCAGGAAAAAGACCGGCAGCTGTCGCACGAGAGCGGCTTCGATCATCATCTGACCAAACCGGTAAACTTCAAAGT
TCTGACAGAACTGATTGCTTCGATCTAA

Upstream 100 bases:

>100_bases
CGATTTTATGGATATTCGCATTAGAGCGCTCCAGATCATATTGAAGTCAGCCAGGAATCCGAAATTTGGAGAGCTTCTTT
CAGGCTTCGGAGCGTGAGTT

Downstream 100 bases:

>100_bases
CTGCGTGTTTTGTCTTCGGGATTACCCGGCTGGTCTTCGATTCGGGTGACCGAACTGTTTATCGTCATGCCAGGCTTCCC
TGGCCCAATCACATGAAAGT

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 835; Mature: 835

Protein sequence:

>835_residues
MLGFEQGSPQCVISILCQKEEGMNERETTSCAELPGWLQGSEMGALIFTHDWIDSSLGPISAWSPALRFAVNMILLMPSA
VLLLWGPKLIQIYNDGYRNLMGAKHPDGLGQPVSECWPEVWHFLAPICEGVMERRQSFSFDDQPLVINRTGSPEEAFFKL
TYSPVPDIKDSFSREVSPDAKQTGVSGVLVTVTETTELVRARAHEAKKIRFKEALAEQALRESEQRFCQALEIETVGIIF
FDSENRITEANDAFLEMSGFSRDDERAGALRCDELIPPEWRMSTSRAAEELKAMGRVAPHEKELFRKDGSRWWALIAMKQ
LLGNEAVAYVVDITERKRVEHSLRESEARFRALAEASPALIWQVDPQGNAVYLNQRYQYMFGKSLEELMPTGWRELLHPD
DAPAYVAAFERALHDRAHLRQRVRARTAEGEWRWLKSYALPWFTVRDEYAGHVGISIDITEAVAAETALLEADRRKDEFL
ATLAHELRNPLAPIASALTLIAGPDGAAEIPRLLPVINRQVNYMVRLVDDLLEISRITSGKVELRQKPTDLAIVLRNAAE
ASMEQIREKELELSISITDTPLIVYGDTVRLEQIFANLLNNAVRYTGRGGKIWLTARQEDHKAVVSVKDNGIGILPGMLP
RLFDMFAQERRSGMGTQEGLGIGLNLVDRLVQMHGGSVEASSEGKDKGSEFTVRLPLSEITTSGKSGQSEKVAFAPQELR
VLVVDDNQDAAEVLCMLLQSMGVDVKAVDSGPAALATLPHYLPDVVLMDIGMPGMDGNEVARRIRVQPQFNNIKLIALTG
WGQEKDRQLSHESGFDHHLTKPVNFKVLTELIASI

Sequences:

>Translated_835_residues
MLGFEQGSPQCVISILCQKEEGMNERETTSCAELPGWLQGSEMGALIFTHDWIDSSLGPISAWSPALRFAVNMILLMPSA
VLLLWGPKLIQIYNDGYRNLMGAKHPDGLGQPVSECWPEVWHFLAPICEGVMERRQSFSFDDQPLVINRTGSPEEAFFKL
TYSPVPDIKDSFSREVSPDAKQTGVSGVLVTVTETTELVRARAHEAKKIRFKEALAEQALRESEQRFCQALEIETVGIIF
FDSENRITEANDAFLEMSGFSRDDERAGALRCDELIPPEWRMSTSRAAEELKAMGRVAPHEKELFRKDGSRWWALIAMKQ
LLGNEAVAYVVDITERKRVEHSLRESEARFRALAEASPALIWQVDPQGNAVYLNQRYQYMFGKSLEELMPTGWRELLHPD
DAPAYVAAFERALHDRAHLRQRVRARTAEGEWRWLKSYALPWFTVRDEYAGHVGISIDITEAVAAETALLEADRRKDEFL
ATLAHELRNPLAPIASALTLIAGPDGAAEIPRLLPVINRQVNYMVRLVDDLLEISRITSGKVELRQKPTDLAIVLRNAAE
ASMEQIREKELELSISITDTPLIVYGDTVRLEQIFANLLNNAVRYTGRGGKIWLTARQEDHKAVVSVKDNGIGILPGMLP
RLFDMFAQERRSGMGTQEGLGIGLNLVDRLVQMHGGSVEASSEGKDKGSEFTVRLPLSEITTSGKSGQSEKVAFAPQELR
VLVVDDNQDAAEVLCMLLQSMGVDVKAVDSGPAALATLPHYLPDVVLMDIGMPGMDGNEVARRIRVQPQFNNIKLIALTG
WGQEKDRQLSHESGFDHHLTKPVNFKVLTELIASI
>Mature_835_residues
MLGFEQGSPQCVISILCQKEEGMNERETTSCAELPGWLQGSEMGALIFTHDWIDSSLGPISAWSPALRFAVNMILLMPSA
VLLLWGPKLIQIYNDGYRNLMGAKHPDGLGQPVSECWPEVWHFLAPICEGVMERRQSFSFDDQPLVINRTGSPEEAFFKL
TYSPVPDIKDSFSREVSPDAKQTGVSGVLVTVTETTELVRARAHEAKKIRFKEALAEQALRESEQRFCQALEIETVGIIF
FDSENRITEANDAFLEMSGFSRDDERAGALRCDELIPPEWRMSTSRAAEELKAMGRVAPHEKELFRKDGSRWWALIAMKQ
LLGNEAVAYVVDITERKRVEHSLRESEARFRALAEASPALIWQVDPQGNAVYLNQRYQYMFGKSLEELMPTGWRELLHPD
DAPAYVAAFERALHDRAHLRQRVRARTAEGEWRWLKSYALPWFTVRDEYAGHVGISIDITEAVAAETALLEADRRKDEFL
ATLAHELRNPLAPIASALTLIAGPDGAAEIPRLLPVINRQVNYMVRLVDDLLEISRITSGKVELRQKPTDLAIVLRNAAE
ASMEQIREKELELSISITDTPLIVYGDTVRLEQIFANLLNNAVRYTGRGGKIWLTARQEDHKAVVSVKDNGIGILPGMLP
RLFDMFAQERRSGMGTQEGLGIGLNLVDRLVQMHGGSVEASSEGKDKGSEFTVRLPLSEITTSGKSGQSEKVAFAPQELR
VLVVDDNQDAAEVLCMLLQSMGVDVKAVDSGPAALATLPHYLPDVVLMDIGMPGMDGNEVARRIRVQPQFNNIKLIALTG
WGQEKDRQLSHESGFDHHLTKPVNFKVLTELIASI

Specific function: Member of the two-component regulatory system ArcB/ArcA. Sensor-regulator protein for anaerobic repression of the arc modulon. Activates ArcA via a four-step phosphorelay. ArcB can also dephosphorylate ArcA by a reverse phosphorelay involving His- 717 and

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=505, Percent_Identity=27.5247524752475, Blast_Score=166, Evalue=7e-42,
Organism=Escherichia coli, GI1788713, Length=535, Percent_Identity=25.4205607476636, Blast_Score=131, Evalue=2e-31,
Organism=Escherichia coli, GI87081816, Length=367, Percent_Identity=29.1553133514986, Blast_Score=130, Evalue=4e-31,
Organism=Escherichia coli, GI145693157, Length=266, Percent_Identity=31.203007518797, Blast_Score=124, Evalue=3e-29,
Organism=Escherichia coli, GI1788393, Length=223, Percent_Identity=32.7354260089686, Blast_Score=111, Evalue=2e-25,
Organism=Escherichia coli, GI1789149, Length=226, Percent_Identity=33.1858407079646, Blast_Score=103, Evalue=5e-23,
Organism=Escherichia coli, GI1790436, Length=233, Percent_Identity=29.6137339055794, Blast_Score=97, Evalue=6e-21,
Organism=Escherichia coli, GI1786912, Length=245, Percent_Identity=31.0204081632653, Blast_Score=93, Evalue=7e-20,
Organism=Escherichia coli, GI1786600, Length=228, Percent_Identity=30.7017543859649, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1786783, Length=223, Percent_Identity=28.6995515695067, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1788549, Length=369, Percent_Identity=24.9322493224932, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1790861, Length=220, Percent_Identity=29.0909090909091, Blast_Score=80, Evalue=6e-16,
Organism=Escherichia coli, GI1790551, Length=284, Percent_Identity=28.8732394366197, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1786599, Length=116, Percent_Identity=29.3103448275862, Blast_Score=63, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR014409
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 93215; Mature: 93215

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLGFEQGSPQCVISILCQKEEGMNERETTSCAELPGWLQGSEMGALIFTHDWIDSSLGPI
CCCCCCCCCHHHHHHHHHHHCCCCHHHCCHHHHCCCCCCCCCCCEEEEEECHHCCCCCCC
SAWSPALRFAVNMILLMPSAVLLLWGPKLIQIYNDGYRNLMGAKHPDGLGQPVSECWPEV
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHEEEHHCCHHHHCCCCCCCCCCCCHHHHHHHH
WHFLAPICEGVMERRQSFSFDDQPLVINRTGSPEEAFFKLTYSPVPDIKDSFSREVSPDA
HHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCEEEEEECCCCCCHHHHHCCCCCCCH
KQTGVSGVLVTVTETTELVRARAHEAKKIRFKEALAEQALRESEQRFCQALEIETVGIIF
HHCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEE
FDSENRITEANDAFLEMSGFSRDDERAGALRCDELIPPEWRMSTSRAAEELKAMGRVAPH
ECCCCCEECCCCCEEEECCCCCCCHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCC
EKELFRKDGSRWWALIAMKQLLGNEAVAYVVDITERKRVEHSLRESEARFRALAEASPAL
HHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCEE
IWQVDPQGNAVYLNQRYQYMFGKSLEELMPTGWRELLHPDDAPAYVAAFERALHDRAHLR
EEEECCCCCEEEEECCHHHHHHCCHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHH
QRVRARTAEGEWRWLKSYALPWFTVRDEYAGHVGISIDITEAVAAETALLEADRRKDEFL
HHHHHCCCCCHHHHHHHHCCCEEEECCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHH
ATLAHELRNPLAPIASALTLIAGPDGAAEIPRLLPVINRQVNYMVRLVDDLLEISRITSG
HHHHHHHHCCHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KVELRQKPTDLAIVLRNAAEASMEQIREKELELSISITDTPLIVYGDTVRLEQIFANLLN
CEEECCCCCCCEEHHHHHHHHHHHHHHHHHEEEEEEEECCCEEEECCCHHHHHHHHHHHH
NAVRYTGRGGKIWLTARQEDHKAVVSVKDNGIGILPGMLPRLFDMFAQERRSGMGTQEGL
HHHEECCCCCEEEEEECCCCCEEEEEECCCCEEECHHHHHHHHHHHHHHHHHCCCCCCCC
GIGLNLVDRLVQMHGGSVEASSEGKDKGSEFTVRLPLSEITTSGKSGQSEKVAFAPQELR
CCCHHHHHHHHHHCCCCEECCCCCCCCCCEEEEEEEHHHHHCCCCCCCCCCEEECCCCCE
VLVVDDNQDAAEVLCMLLQSMGVDVKAVDSGPAALATLPHYLPDVVLMDIGMPGMDGNEV
EEEEECCCCHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHEEECCCCCCCHHHH
ARRIRVQPQFNNIKLIALTGWGQEKDRQLSHESGFDHHLTKPVNFKVLTELIASI
HHHEECCCCCCCEEEEEEECCCCCHHHHCHHCCCCCCCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MLGFEQGSPQCVISILCQKEEGMNERETTSCAELPGWLQGSEMGALIFTHDWIDSSLGPI
CCCCCCCCCHHHHHHHHHHHCCCCHHHCCHHHHCCCCCCCCCCCEEEEEECHHCCCCCCC
SAWSPALRFAVNMILLMPSAVLLLWGPKLIQIYNDGYRNLMGAKHPDGLGQPVSECWPEV
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHEEEHHCCHHHHCCCCCCCCCCCCHHHHHHHH
WHFLAPICEGVMERRQSFSFDDQPLVINRTGSPEEAFFKLTYSPVPDIKDSFSREVSPDA
HHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCEEEEEECCCCCCHHHHHCCCCCCCH
KQTGVSGVLVTVTETTELVRARAHEAKKIRFKEALAEQALRESEQRFCQALEIETVGIIF
HHCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEEE
FDSENRITEANDAFLEMSGFSRDDERAGALRCDELIPPEWRMSTSRAAEELKAMGRVAPH
ECCCCCEECCCCCEEEECCCCCCCHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCC
EKELFRKDGSRWWALIAMKQLLGNEAVAYVVDITERKRVEHSLRESEARFRALAEASPAL
HHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCEE
IWQVDPQGNAVYLNQRYQYMFGKSLEELMPTGWRELLHPDDAPAYVAAFERALHDRAHLR
EEEECCCCCEEEEECCHHHHHHCCHHHHCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHH
QRVRARTAEGEWRWLKSYALPWFTVRDEYAGHVGISIDITEAVAAETALLEADRRKDEFL
HHHHHCCCCCHHHHHHHHCCCEEEECCCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHH
ATLAHELRNPLAPIASALTLIAGPDGAAEIPRLLPVINRQVNYMVRLVDDLLEISRITSG
HHHHHHHHCCHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
KVELRQKPTDLAIVLRNAAEASMEQIREKELELSISITDTPLIVYGDTVRLEQIFANLLN
CEEECCCCCCCEEHHHHHHHHHHHHHHHHHEEEEEEEECCCEEEECCCHHHHHHHHHHHH
NAVRYTGRGGKIWLTARQEDHKAVVSVKDNGIGILPGMLPRLFDMFAQERRSGMGTQEGL
HHHEECCCCCEEEEEECCCCCEEEEEECCCCEEECHHHHHHHHHHHHHHHHHCCCCCCCC
GIGLNLVDRLVQMHGGSVEASSEGKDKGSEFTVRLPLSEITTSGKSGQSEKVAFAPQELR
CCCHHHHHHHHHHCCCCEECCCCCCCCCCEEEEEEEHHHHHCCCCCCCCCCEEECCCCCE
VLVVDDNQDAAEVLCMLLQSMGVDVKAVDSGPAALATLPHYLPDVVLMDIGMPGMDGNEV
EEEEECCCCHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHEEECCCCCCCHHHH
ARRIRVQPQFNNIKLIALTGWGQEKDRQLSHESGFDHHLTKPVNFKVLTELIASI
HHHEECCCCCCCEEEEEEECCCCCHHHHCHHCCCCCCCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]