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The map label for this gene is xylB [H]

Identifier: 82702602

GI number: 82702602

Start: 1681942

End: 1683048

Strand: Reverse

Name: xylB [H]

Synonym: Nmul_A1473

Alternate gene names: 82702602

Gene position: 1683048-1681942 (Counterclockwise)

Preceding gene: 82702604

Following gene: 82702600

Centisome position: 52.86

GC content: 56.19

Gene sequence:

>1107_bases
ATGATGGAGATTCGGGCAGCGACGATTCGACAGAAGGGTGGGCCTTTCAGGATCGAGAATTTGATTCTGGATGAGCCACG
CCCAGATGAGGTGCTGGTTCGTATCGCGGCTACTGGCATGTGTCATACCGACATGGTAGCGCGTGATCAGCTCTATGATG
TCCCCTTACCGATTGTGCTTGGGCATGAAGGTGCGGGTGTTGTCGAACGGGTAGGCAGCAACGTGAAAAAAGTGACGGCA
GGAGATCACGTAGTGCTGACCTATATGTGGTGCGGCCATTGCAGGCCATGTCTCCATGGAGATTTAACCTATTGCCAGAA
TTTCTATGCACTGAATTTTGGCGGCGCCAGGGAAGACGGCAGCAGCTCCGCCCGCGATGCGCATGGTTCGCTTCATGACC
ATTTCTTCGGCCAGTCGTCATTCGGGACTTTTGCTCTTACCCACGAACGTAATGCGATCAAGGTGCCGAGGGAAGCTCCG
CTGGAGCTTCTTGGTCCGCTTGGCTGCGGCATTCAAACTGGCGCCGGTGCAGTGATAAATGCGCTTAAAGTCAATCCAGG
CGCCAGTTTTGCGGCTTTTGGCGGGGGAGCGGTAGGACTGAGTGCGGTAATGGCGGCTCGCGTCACGGGCGCCACAACGA
TTATTGCTGTGGATGTCGTTCCATCCCGGCTCGAGCTGGCGAGAGAGCTCGGGGCAACTCACACGGTTAACAGCCGCGAA
ACCGATCCCGTCGCGACGGTGCGCAAGATCAGTGGCGGGGGGGTAGAATATGCCCTTGAGTCCAGTGGTCGGCCCCAGGT
ATTGCGCCAGGCCATCGATGCGCTGGGCATTCGCGGCACTTGCGGCATTGTCGGCGCGCCCGCTCTTGGGACAGAGGTCA
GCTTTGACGTGAATGGCGTAATGACCACCGGCAAACGCATCCTTGGGATCATCGAAGGCGATAGCATACCCGACCTCTTC
ATACCAGCCCTTGTCGAGCTTTACATGCAGGGACGCTTTCCATTCGACAAGCTCGTGAAGTTTTACCCTCTTGACAGGAT
CAATGAAGCGGCAGAGGATAGTGAGAAGGGTATTACCATCAAGCCGATTATCAGGGTGGCATTATAA

Upstream 100 bases:

>100_bases
ATTGAGGATAAGGTAATTTTTTATATGGGCAGAAATTTCTGCTGCTCTTCTATGCGAAAGTGAACCGGGGCTTGTGAGAG
ATAAATAGAGGAGGCTGCAT

Downstream 100 bases:

>100_bases
GAACCCTATGCTTCTGCTTCTTGCATATGCGGGAAAGGGAGGGGAAAACCCCTTTCCGCGAATATTGCACTCACTCCTCA
TGCAGTAAGCGAAAACGCTC

Product: zinc-containing alcohol dehydrogenase superfamily protein

Products: NA

Alternate protein names: Benzyl alcohol dehydrogenase; BADH [H]

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MMEIRAATIRQKGGPFRIENLILDEPRPDEVLVRIAATGMCHTDMVARDQLYDVPLPIVLGHEGAGVVERVGSNVKKVTA
GDHVVLTYMWCGHCRPCLHGDLTYCQNFYALNFGGAREDGSSSARDAHGSLHDHFFGQSSFGTFALTHERNAIKVPREAP
LELLGPLGCGIQTGAGAVINALKVNPGASFAAFGGGAVGLSAVMAARVTGATTIIAVDVVPSRLELARELGATHTVNSRE
TDPVATVRKISGGGVEYALESSGRPQVLRQAIDALGIRGTCGIVGAPALGTEVSFDVNGVMTTGKRILGIIEGDSIPDLF
IPALVELYMQGRFPFDKLVKFYPLDRINEAAEDSEKGITIKPIIRVAL

Sequences:

>Translated_368_residues
MMEIRAATIRQKGGPFRIENLILDEPRPDEVLVRIAATGMCHTDMVARDQLYDVPLPIVLGHEGAGVVERVGSNVKKVTA
GDHVVLTYMWCGHCRPCLHGDLTYCQNFYALNFGGAREDGSSSARDAHGSLHDHFFGQSSFGTFALTHERNAIKVPREAP
LELLGPLGCGIQTGAGAVINALKVNPGASFAAFGGGAVGLSAVMAARVTGATTIIAVDVVPSRLELARELGATHTVNSRE
TDPVATVRKISGGGVEYALESSGRPQVLRQAIDALGIRGTCGIVGAPALGTEVSFDVNGVMTTGKRILGIIEGDSIPDLF
IPALVELYMQGRFPFDKLVKFYPLDRINEAAEDSEKGITIKPIIRVAL
>Mature_368_residues
MMEIRAATIRQKGGPFRIENLILDEPRPDEVLVRIAATGMCHTDMVARDQLYDVPLPIVLGHEGAGVVERVGSNVKKVTA
GDHVVLTYMWCGHCRPCLHGDLTYCQNFYALNFGGAREDGSSSARDAHGSLHDHFFGQSSFGTFALTHERNAIKVPREAP
LELLGPLGCGIQTGAGAVINALKVNPGASFAAFGGGAVGLSAVMAARVTGATTIIAVDVVPSRLELARELGATHTVNSRE
TDPVATVRKISGGGVEYALESSGRPQVLRQAIDALGIRGTCGIVGAPALGTEVSFDVNGVMTTGKRILGIIEGDSIPDLF
IPALVELYMQGRFPFDKLVKFYPLDRINEAAEDSEKGITIKPIIRVAL

Specific function: Oxidizes primary alcohols with an aromatic or cyclohex- 1-ene ring. It is highly specific for benzyl alcohol [H]

COG id: COG1062

COG function: function code C; Zn-dependent alcohol dehydrogenases, class III

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501929, Length=371, Percent_Identity=33.9622641509434, Blast_Score=202, Evalue=3e-52,
Organism=Homo sapiens, GI34577061, Length=371, Percent_Identity=33.6927223719677, Blast_Score=201, Evalue=9e-52,
Organism=Homo sapiens, GI156523966, Length=371, Percent_Identity=34.2318059299191, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI4501933, Length=371, Percent_Identity=32.6145552560647, Blast_Score=193, Evalue=3e-49,
Organism=Homo sapiens, GI4501939, Length=364, Percent_Identity=34.3406593406593, Blast_Score=191, Evalue=9e-49,
Organism=Homo sapiens, GI71565154, Length=371, Percent_Identity=32.8840970350404, Blast_Score=189, Evalue=3e-48,
Organism=Homo sapiens, GI71565152, Length=373, Percent_Identity=32.9758713136729, Blast_Score=189, Evalue=4e-48,
Organism=Homo sapiens, GI71743840, Length=369, Percent_Identity=28.9972899728997, Blast_Score=165, Evalue=5e-41,
Organism=Homo sapiens, GI262073058, Length=369, Percent_Identity=28.9972899728997, Blast_Score=165, Evalue=6e-41,
Organism=Homo sapiens, GI156627571, Length=373, Percent_Identity=26.0053619302949, Blast_Score=91, Evalue=1e-18,
Organism=Escherichia coli, GI1786552, Length=374, Percent_Identity=35.5614973262032, Blast_Score=160, Evalue=9e-41,
Organism=Escherichia coli, GI1788073, Length=378, Percent_Identity=26.984126984127, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI1788407, Length=274, Percent_Identity=26.2773722627737, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1790045, Length=304, Percent_Identity=27.6315789473684, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788075, Length=319, Percent_Identity=29.153605015674, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI87081918, Length=290, Percent_Identity=26.8965517241379, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1786518, Length=328, Percent_Identity=28.3536585365854, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787863, Length=253, Percent_Identity=25.296442687747, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786825, Length=262, Percent_Identity=27.8625954198473, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87082125, Length=296, Percent_Identity=24.3243243243243, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25146526, Length=378, Percent_Identity=33.0687830687831, Blast_Score=185, Evalue=4e-47,
Organism=Caenorhabditis elegans, GI71997431, Length=380, Percent_Identity=32.8947368421053, Blast_Score=180, Evalue=1e-45,
Organism=Caenorhabditis elegans, GI17565904, Length=340, Percent_Identity=33.5294117647059, Blast_Score=161, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI17562584, Length=293, Percent_Identity=29.3515358361775, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71988145, Length=320, Percent_Identity=27.1875, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562876, Length=365, Percent_Identity=23.5616438356164, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17562582, Length=320, Percent_Identity=27.1875, Blast_Score=78, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17562878, Length=232, Percent_Identity=27.5862068965517, Blast_Score=78, Evalue=9e-15,
Organism=Saccharomyces cerevisiae, GI6320033, Length=364, Percent_Identity=31.5934065934066, Blast_Score=177, Evalue=3e-45,
Organism=Saccharomyces cerevisiae, GI6323961, Length=365, Percent_Identity=27.1232876712329, Blast_Score=94, Evalue=5e-20,
Organism=Saccharomyces cerevisiae, GI6323099, Length=297, Percent_Identity=28.2828282828283, Blast_Score=91, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6319621, Length=293, Percent_Identity=26.6211604095563, Blast_Score=86, Evalue=6e-18,
Organism=Saccharomyces cerevisiae, GI6324486, Length=367, Percent_Identity=26.158038147139, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6323729, Length=290, Percent_Identity=25.8620689655172, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6319258, Length=288, Percent_Identity=27.4305555555556, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI17737895, Length=377, Percent_Identity=33.42175066313, Blast_Score=191, Evalue=6e-49,
Organism=Drosophila melanogaster, GI17137530, Length=271, Percent_Identity=28.0442804428044, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI17737897, Length=235, Percent_Identity=29.3617021276596, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.90 [H]

Molecular weight: Translated: 39097; Mature: 39097

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00059 ADH_ZINC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMEIRAATIRQKGGPFRIENLILDEPRPDEVLVRIAATGMCHTDMVARDQLYDVPLPIVL
CCCCCCHHHHCCCCCEEEEEEEECCCCCHHHEEEEHHCCCCHHHHHHHHHHCCCCCCEEE
GHEGAGVVERVGSNVKKVTAGDHVVLTYMWCGHCRPCLHGDLTYCQNFYALNFGGAREDG
CCCCCHHHHHHCCCCEEEECCCEEEEEEEECCCCCCHHCCCHHHHCCEEEEECCCCCCCC
SSSARDAHGSLHDHFFGQSSFGTFALTHERNAIKVPREAPLELLGPLGCGIQTGAGAVIN
CCCCHHCCCCHHHHHCCCCCCCEEEEEECCCCEECCCCCCHHHHCCCCCCCCCCCCCEEE
ALKVNPGASFAAFGGGAVGLSAVMAARVTGATTIIAVDVVPSRLELARELGATHTVNSRE
EEEECCCCCEEECCCCHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHCCCCCCCCCC
TDPVATVRKISGGGVEYALESSGRPQVLRQAIDALGIRGTCGIVGAPALGTEVSFDVNGV
CCCHHHHHEECCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCEEECCCCCCEEEEECCCE
MTTGKRILGIIEGDSIPDLFIPALVELYMQGRFPFDKLVKFYPLDRINEAAEDSEKGITI
EECCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHCCEEE
KPIIRVAL
EHHHEECC
>Mature Secondary Structure
MMEIRAATIRQKGGPFRIENLILDEPRPDEVLVRIAATGMCHTDMVARDQLYDVPLPIVL
CCCCCCHHHHCCCCCEEEEEEEECCCCCHHHEEEEHHCCCCHHHHHHHHHHCCCCCCEEE
GHEGAGVVERVGSNVKKVTAGDHVVLTYMWCGHCRPCLHGDLTYCQNFYALNFGGAREDG
CCCCCHHHHHHCCCCEEEECCCEEEEEEEECCCCCCHHCCCHHHHCCEEEEECCCCCCCC
SSSARDAHGSLHDHFFGQSSFGTFALTHERNAIKVPREAPLELLGPLGCGIQTGAGAVIN
CCCCHHCCCCHHHHHCCCCCCCEEEEEECCCCEECCCCCCHHHHCCCCCCCCCCCCCEEE
ALKVNPGASFAAFGGGAVGLSAVMAARVTGATTIIAVDVVPSRLELARELGATHTVNSRE
EEEECCCCCEEECCCCHHHHHHHHHHHHCCCEEEEEEECCCHHHHHHHHHCCCCCCCCCC
TDPVATVRKISGGGVEYALESSGRPQVLRQAIDALGIRGTCGIVGAPALGTEVSFDVNGV
CCCHHHHHEECCCCEEEEECCCCCHHHHHHHHHHCCCCCCCCEEECCCCCCEEEEECCCE
MTTGKRILGIIEGDSIPDLFIPALVELYMQGRFPFDKLVKFYPLDRINEAAEDSEKGITI
EECCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHHHCCEEE
KPIIRVAL
EHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8496150; 1989592 [H]