Click here to switch to the map view.

The map label for this gene is galE [H]

Identifier: 78779700

GI number: 78779700

Start: 1228713

End: 1229771

Strand: Reverse

Name: galE [H]

Synonym: PMT9312_1317

Alternate gene names: 78779700

Gene position: 1229771-1228713 (Counterclockwise)

Preceding gene: 78779702

Following gene: 78779699

Centisome position: 71.95

GC content: 28.99

Gene sequence:

>1059_bases
ATGTCAAGTAATAATGTTTTAGTGACTGGTGGTATTGGTTATATAGGGATCCACACCTGCTTTACATTACTTGAAAGAGG
ATATAACGTATATGTTCTAGATTCATTAATAAATAGTTCTGAAAAGACACTTGAAATAATTAAGGAATATAGTAAATCAC
TTAATTCAAAAGGTTTTAAGAATATATTTAAATTTTATAAAGGTGATATTCGGAATATAAAAAATATAGAAAATGTATTT
TCAGATGCACTTTTGAATTCAAAACCAATTGGTGGTGTAATTCATTTCGCTGGGAAAAAGTCAGTAAATGAATCTATTAA
TTTCCCAATGGAATATTGGGAAACAAACCTCTTAGGAACAATTAATTTGATTAGGGTAATGAATAGTTATAGTTGCTTCA
ATTTTATTTTTAGTAGTAGTGCTTCAGTATATGGAAAAAATTCAATAAGTCCTATTAAAGAATTTGAAAGGATTGAACCA
ATAAATCCTTATGGGAATACAAAAGCTACAATTGAAAAGTTTCTAATAGATGTTTTCAACAGTAAACCAAATTCTTGGAG
GATTATCTTATTGCGATACTTTAATCCAATAGGCTCACACCCTAGCGGATTAATTGGAGAATCACCTTTAGAAGAATCAA
CAAATATTTTTCCAAAAATTTGTGAAGTTGCGATTAGGGAGAACAATGCGTTTAAAATTTATGGTAATGATTGGCCTACA
AAAGATGGTACTTGTATCAGGGATTATATTCATATTATGGATTTAGTTGAAGGACACATTTGTTCTTACAATCATCTTCT
GTCTCATGATCCTGAAATAAATGCTTTTAATTTAGGGACTGGTAAAGGTACAAGTGTACTTGAATTATTATCTATTTTTC
AGGAAGTGAATAAATGTAAAATATTTTATGAATATGAACAACCTAGGAAAGGAGATGTAGGGGTATGTTTTGCTGATAAC
ACTAAGGCAAAAAAGATTATGAATTGGTACCCAAAAAAGTCAATAAATGAAATGTGTAAAGATGGATGGAGATGGTATAA
AAGTAACTTTAAAAATTGA

Upstream 100 bases:

>100_bases
TTTTAGTATTTAAATCTCGAAATATTTAATCAATTAGTTAAAAACTTCTTTACATTTAAGCTAAAGTTTTTTAAAGAGAA
GAAAAATTAAATTCTTATCA

Downstream 100 bases:

>100_bases
TTTATAAGAATTAATTTATATTTAAAAAAGTCAATTTAGAGTTCCTTTTTTATAGGGTATATATTAAGATTTTTGATTGA
ATTCTTTTATTACGTTAATA

Product: UDP-galactose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MSSNNVLVTGGIGYIGIHTCFTLLERGYNVYVLDSLINSSEKTLEIIKEYSKSLNSKGFKNIFKFYKGDIRNIKNIENVF
SDALLNSKPIGGVIHFAGKKSVNESINFPMEYWETNLLGTINLIRVMNSYSCFNFIFSSSASVYGKNSISPIKEFERIEP
INPYGNTKATIEKFLIDVFNSKPNSWRIILLRYFNPIGSHPSGLIGESPLEESTNIFPKICEVAIRENNAFKIYGNDWPT
KDGTCIRDYIHIMDLVEGHICSYNHLLSHDPEINAFNLGTGKGTSVLELLSIFQEVNKCKIFYEYEQPRKGDVGVCFADN
TKAKKIMNWYPKKSINEMCKDGWRWYKSNFKN

Sequences:

>Translated_352_residues
MSSNNVLVTGGIGYIGIHTCFTLLERGYNVYVLDSLINSSEKTLEIIKEYSKSLNSKGFKNIFKFYKGDIRNIKNIENVF
SDALLNSKPIGGVIHFAGKKSVNESINFPMEYWETNLLGTINLIRVMNSYSCFNFIFSSSASVYGKNSISPIKEFERIEP
INPYGNTKATIEKFLIDVFNSKPNSWRIILLRYFNPIGSHPSGLIGESPLEESTNIFPKICEVAIRENNAFKIYGNDWPT
KDGTCIRDYIHIMDLVEGHICSYNHLLSHDPEINAFNLGTGKGTSVLELLSIFQEVNKCKIFYEYEQPRKGDVGVCFADN
TKAKKIMNWYPKKSINEMCKDGWRWYKSNFKN
>Mature_351_residues
SSNNVLVTGGIGYIGIHTCFTLLERGYNVYVLDSLINSSEKTLEIIKEYSKSLNSKGFKNIFKFYKGDIRNIKNIENVFS
DALLNSKPIGGVIHFAGKKSVNESINFPMEYWETNLLGTINLIRVMNSYSCFNFIFSSSASVYGKNSISPIKEFERIEPI
NPYGNTKATIEKFLIDVFNSKPNSWRIILLRYFNPIGSHPSGLIGESPLEESTNIFPKICEVAIRENNAFKIYGNDWPTK
DGTCIRDYIHIMDLVEGHICSYNHLLSHDPEINAFNLGTGKGTSVLELLSIFQEVNKCKIFYEYEQPRKGDVGVCFADNT
KAKKIMNWYPKKSINEMCKDGWRWYKSNFKN

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=348, Percent_Identity=37.6436781609195, Blast_Score=247, Evalue=1e-65,
Organism=Homo sapiens, GI56118217, Length=348, Percent_Identity=37.6436781609195, Blast_Score=247, Evalue=1e-65,
Organism=Homo sapiens, GI189083684, Length=348, Percent_Identity=37.6436781609195, Blast_Score=247, Evalue=1e-65,
Organism=Homo sapiens, GI7657641, Length=362, Percent_Identity=25.9668508287293, Blast_Score=86, Evalue=7e-17,
Organism=Escherichia coli, GI1786974, Length=341, Percent_Identity=40.7624633431085, Blast_Score=283, Evalue=1e-77,
Organism=Caenorhabditis elegans, GI71982038, Length=352, Percent_Identity=36.6477272727273, Blast_Score=240, Evalue=9e-64,
Organism=Caenorhabditis elegans, GI71982035, Length=352, Percent_Identity=36.9318181818182, Blast_Score=238, Evalue=2e-63,
Organism=Saccharomyces cerevisiae, GI6319493, Length=355, Percent_Identity=39.7183098591549, Blast_Score=266, Evalue=5e-72,
Organism=Drosophila melanogaster, GI19923002, Length=351, Percent_Identity=39.6011396011396, Blast_Score=261, Evalue=4e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040
- InterPro:   IPR008089 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 40180; Mature: 40049

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSNNVLVTGGIGYIGIHTCFTLLERGYNVYVLDSLINSSEKTLEIIKEYSKSLNSKGFK
CCCCCEEEECCCHHHHHHHHHHHHHCCCCEEEEHHHHCCCHHHHHHHHHHHHHHCCCHHH
NIFKFYKGDIRNIKNIENVFSDALLNSKPIGGVIHFAGKKSVNESINFPMEYWETNLLGT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCHHHHHCCHHHH
INLIRVMNSYSCFNFIFSSSASVYGKNSISPIKEFERIEPINPYGNTKATIEKFLIDVFN
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHC
SKPNSWRIILLRYFNPIGSHPSGLIGESPLEESTNIFPKICEVAIRENNAFKIYGNDWPT
CCCCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCC
KDGTCIRDYIHIMDLVEGHICSYNHLLSHDPEINAFNLGTGKGTSVLELLSIFQEVNKCK
CCCHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHEE
IFYEYEQPRKGDVGVCFADNTKAKKIMNWYPKKSINEMCKDGWRWYKSNFKN
EEEEECCCCCCCEEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SSNNVLVTGGIGYIGIHTCFTLLERGYNVYVLDSLINSSEKTLEIIKEYSKSLNSKGFK
CCCCEEEECCCHHHHHHHHHHHHHCCCCEEEEHHHHCCCHHHHHHHHHHHHHHCCCHHH
NIFKFYKGDIRNIKNIENVFSDALLNSKPIGGVIHFAGKKSVNESINFPMEYWETNLLGT
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCHHHHHCCHHHH
INLIRVMNSYSCFNFIFSSSASVYGKNSISPIKEFERIEPINPYGNTKATIEKFLIDVFN
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHC
SKPNSWRIILLRYFNPIGSHPSGLIGESPLEESTNIFPKICEVAIRENNAFKIYGNDWPT
CCCCCEEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCC
KDGTCIRDYIHIMDLVEGHICSYNHLLSHDPEINAFNLGTGKGTSVLELLSIFQEVNKCK
CCCHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCEEECCCCCCHHHHHHHHHHHHHHHEE
IFYEYEQPRKGDVGVCFADNTKAKKIMNWYPKKSINEMCKDGWRWYKSNFKN
EEEEECCCCCCCEEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8978088; 8969509; 9384377 [H]