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The map label for this gene is nadA [H]

Identifier: 78779063

GI number: 78779063

Start: 639903

End: 640817

Strand: Reverse

Name: nadA [H]

Synonym: PMT9312_0678

Alternate gene names: 78779063

Gene position: 640817-639903 (Counterclockwise)

Preceding gene: 78779065

Following gene: 78779059

Centisome position: 37.49

GC content: 33.22

Gene sequence:

>915_bases
TTGATTTCTGAAATAAAGGAGCGTTGCAAAAAAGCTAATGCTATTATTCTTGCGCACTATTATCAAGCTCCAGAGATTCA
GGAAATTGCAGATTTTATTGGCGATTCATTAGATCTATCTAGGAAAGCTGCAAATAATGATGCAGATATAATAATTTTTT
GCGGTGTACACTTTATGGCCGAAACTGCAAAAATACTTAGCCCTAATAAAACAGTCCTATTACCAGATATTGACGCAGGA
TGCTCATTAGCAGACGATTGTCCTTCAGATAAATTTCAAAAGTTCAGGGAAGAAAATCCAGATCACTATGTTGTAAGTTA
TATAAATTGCACTGCAGAAGTAAAAGCTCAAAGTGATCTGATATGTACAAGTAGTAATGCAGTCTCATTAATTAAAAAGA
TACCACAAGATAAAAAGATAATATTTGCACCAGATCAGAACCTTGGGAGATGGGTGCAGAAAAATTCAGGAAGAGATCTT
AAATTATGGCCTGGCAGCTGTATTGTTCATGAATCATTTAGTGAAGAAGCACTTTTAAAACTAAAATACCAAAATCCAGG
ATCAAAAGTAATTGCTCATCCTGAATGTAGTCAAAATTTACTACTTCTCTCGGACTTTATTGGATCAACAAGTAAACTGC
TTGATTTCGTAAGTAAAGATTCATCTAAAACTTACATGGTATTAACTGAACCTGGAATAATCCACCAAATGAAGAAGAAA
GAACCTAACAAAATTTTTATTGAAGTCCCCGATATAGAAGGTTGTAAATGTAACGAGTGTCCATATATGAAATTAAATAC
TTTAGAAAAAATTCTTGATTGTTTGAAAAATAATTCCCCGTCTATCGAACTTGACCCAGAAATACTAAGAAGAGCCTATG
TACCGATAAAGAGAATGTTGGATATGAGTAATTAA

Upstream 100 bases:

>100_bases
TTTTTCTGTTTAAAGGCATATAATCTATTTAGAGATATTCTAAATCCTGACCAGTATAACTTCTACTGCAAAACAGAAAT
CAGTTCAAAACGAAGAGGAT

Downstream 100 bases:

>100_bases
TTTAATGAAAATACTTTATTTTCCTTATTAATTTTTAGGAGTGCATTAAGGTTTGCAGTGTTTGGATTAAATTCACTTAT
ATTATTATTTCTTTTAATTA

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MISEIKERCKKANAIILAHYYQAPEIQEIADFIGDSLDLSRKAANNDADIIIFCGVHFMAETAKILSPNKTVLLPDIDAG
CSLADDCPSDKFQKFREENPDHYVVSYINCTAEVKAQSDLICTSSNAVSLIKKIPQDKKIIFAPDQNLGRWVQKNSGRDL
KLWPGSCIVHESFSEEALLKLKYQNPGSKVIAHPECSQNLLLLSDFIGSTSKLLDFVSKDSSKTYMVLTEPGIIHQMKKK
EPNKIFIEVPDIEGCKCNECPYMKLNTLEKILDCLKNNSPSIELDPEILRRAYVPIKRMLDMSN

Sequences:

>Translated_304_residues
MISEIKERCKKANAIILAHYYQAPEIQEIADFIGDSLDLSRKAANNDADIIIFCGVHFMAETAKILSPNKTVLLPDIDAG
CSLADDCPSDKFQKFREENPDHYVVSYINCTAEVKAQSDLICTSSNAVSLIKKIPQDKKIIFAPDQNLGRWVQKNSGRDL
KLWPGSCIVHESFSEEALLKLKYQNPGSKVIAHPECSQNLLLLSDFIGSTSKLLDFVSKDSSKTYMVLTEPGIIHQMKKK
EPNKIFIEVPDIEGCKCNECPYMKLNTLEKILDCLKNNSPSIELDPEILRRAYVPIKRMLDMSN
>Mature_304_residues
MISEIKERCKKANAIILAHYYQAPEIQEIADFIGDSLDLSRKAANNDADIIIFCGVHFMAETAKILSPNKTVLLPDIDAG
CSLADDCPSDKFQKFREENPDHYVVSYINCTAEVKAQSDLICTSSNAVSLIKKIPQDKKIIFAPDQNLGRWVQKNSGRDL
KLWPGSCIVHESFSEEALLKLKYQNPGSKVIAHPECSQNLLLLSDFIGSTSKLLDFVSKDSSKTYMVLTEPGIIHQMKKK
EPNKIFIEVPDIEGCKCNECPYMKLNTLEKILDCLKNNSPSIELDPEILRRAYVPIKRMLDMSN

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=311, Percent_Identity=40.5144694533762, Blast_Score=246, Evalue=1e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 34187; Mature: 34187

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISEIKERCKKANAIILAHYYQAPEIQEIADFIGDSLDLSRKAANNDADIIIFCGVHFMA
CCHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHCCCCCHHHHCCCCCCCEEEEECHHHHH
ETAKILSPNKTVLLPDIDAGCSLADDCPSDKFQKFREENPDHYVVSYINCTAEVKAQSDL
HHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEEEEEEEECCCCCE
ICTSSNAVSLIKKIPQDKKIIFAPDQNLGRWVQKNSGRDLKLWPGSCIVHESFSEEALLK
EEECCHHHHHHHHCCCCCEEEECCCCCHHHHHHCCCCCEEEECCCCEEEECCCCCCEEEE
LKYQNPGSKVIAHPECSQNLLLLSDFIGSTSKLLDFVSKDSSKTYMVLTEPGIIHQMKKK
EEECCCCCCEEECCCCCCCEEEEHHHHCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHCC
EPNKIFIEVPDIEGCKCNECPYMKLNTLEKILDCLKNNSPSIELDPEILRRAYVPIKRML
CCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHH
DMSN
CCCC
>Mature Secondary Structure
MISEIKERCKKANAIILAHYYQAPEIQEIADFIGDSLDLSRKAANNDADIIIFCGVHFMA
CCHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHCCCCCHHHHCCCCCCCEEEEECHHHHH
ETAKILSPNKTVLLPDIDAGCSLADDCPSDKFQKFREENPDHYVVSYINCTAEVKAQSDL
HHHHHCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCEEEEEEEEEEEEECCCCCE
ICTSSNAVSLIKKIPQDKKIIFAPDQNLGRWVQKNSGRDLKLWPGSCIVHESFSEEALLK
EEECCHHHHHHHHCCCCCEEEECCCCCHHHHHHCCCCCEEEECCCCEEEECCCCCCEEEE
LKYQNPGSKVIAHPECSQNLLLLSDFIGSTSKLLDFVSKDSSKTYMVLTEPGIIHQMKKK
EEECCCCCCEEECCCCCCCEEEEHHHHCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHCC
EPNKIFIEVPDIEGCKCNECPYMKLNTLEKILDCLKNNSPSIELDPEILRRAYVPIKRML
CCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHH
DMSN
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA