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The map label for this gene is aspC [H]

Identifier: 78779059

GI number: 78779059

Start: 635414

End: 636592

Strand: Reverse

Name: aspC [H]

Synonym: PMT9312_0674

Alternate gene names: 78779059

Gene position: 636592-635414 (Counterclockwise)

Preceding gene: 78779063

Following gene: 78779058

Centisome position: 37.24

GC content: 32.57

Gene sequence:

>1179_bases
ATGAGCCAAGTTAATTTATCTGAACGGGCACTTTCAATTGAGCCTTCTCTTACATTGCAGATAAGTGCTAAAGCAAATCA
ATTATCTGCAGAAGGAGTAGATATTTGCAATTTAAGTGCAGGAGAACCTGACTTTAATGCCCCAAAAGAAGTTATAGAAG
CTACAAGTAAAGCTATATTTGATGGATTTACAAAGTACGGACCCGCAGCAGGAAATTTAGATCTCCGAAAAGCAATTGCA
AATAAACTTCGAATTCAAAACAATTTAAATTATGAATTTGAAAATGTAATGGTCACAAATGGTGCTAAGCAAGCAATATA
TAATCTTTTCCAAGTTTTGTTAAATATTGGAGACGAAGTTATTATTCCTTCTCCATACTGGTTAAGTTATCCCCAAATGG
TTAGGTTGGCGGGTGGAAAACCAATCTTTACAAATTCTTCTGCAGAAGATGGATTTAAAATAGATATAAAAGATTTGAAG
TCTAAAATCTCTTCAAAAACTAAATTTATAATTATCAATTCTCCTAATAACCCCACTGGGAGAGTTATGTCAAAGGAAGA
ATTATTGCAAATTGCCGATATAGTCAGAGAAAATCCAAATATCAATATTCTTTCTGATGAGATTTACGAACTAATCCTTA
AAAAAGAATTTAAACACTACAGTATATCTTCACAAGCAAATGACTTAAAAGATAGGATTTTTATAATAAATGGGTTTGCG
AAAGGATGGGCCATGACTGGCTGGAGGATAGGTTATTTAGTAGGTCCCAAAGATGTAATCAAAGCATCCTCAGCATTACA
AAGTCAAAGCACAAGTAATGTTTGCTCTTTTGTTCAAAAAGGTGCTTTAGAGGCTTTAAAAATTAATAATGAGTTTTTCT
CAATGATAAATAGCCATTATGATCAAAGAAGAAGTCTTCTATATGAGGGCCTTAAGAATATAAATGGGATTTATATTGAA
GAACCTAATGGAGCATTTTACGCATTTCCAAGATTACCTAACTCCTCAATTACTTCTGTTGATTTCTGCAATAAAGCTCT
TCAAGATTACGGATTAGTTGTTGTACCTGGAAAAGCTTTTGGGGCTGACGAATGTATAAGAATTTCTTGTGCCACTTCAG
AGATTAAAATTAAGGATGGTTTAGAAAGATTTAAAAAAGCAATCTCTAAATACTTTTAA

Upstream 100 bases:

>100_bases
AAGAAAATGAACTAAATTAAACCATTATGTGATAGTTTTATTTATCCTTAATTTATGCGTTTGTCATTATTAAAAGTCAT
ATTTTAAAAGTTATAAGTCA

Downstream 100 bases:

>100_bases
TTTCAACTAAACAATGTTCAATTTAAAAAATTTCTTACTAAGTTCATCTCTAATATTTTCTTTTTTTTCATCACCTTTAT
TTGCAAATCCAAAAGTTTTA

Product: L-aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 392; Mature: 391

Protein sequence:

>392_residues
MSQVNLSERALSIEPSLTLQISAKANQLSAEGVDICNLSAGEPDFNAPKEVIEATSKAIFDGFTKYGPAAGNLDLRKAIA
NKLRIQNNLNYEFENVMVTNGAKQAIYNLFQVLLNIGDEVIIPSPYWLSYPQMVRLAGGKPIFTNSSAEDGFKIDIKDLK
SKISSKTKFIIINSPNNPTGRVMSKEELLQIADIVRENPNINILSDEIYELILKKEFKHYSISSQANDLKDRIFIINGFA
KGWAMTGWRIGYLVGPKDVIKASSALQSQSTSNVCSFVQKGALEALKINNEFFSMINSHYDQRRSLLYEGLKNINGIYIE
EPNGAFYAFPRLPNSSITSVDFCNKALQDYGLVVVPGKAFGADECIRISCATSEIKIKDGLERFKKAISKYF

Sequences:

>Translated_392_residues
MSQVNLSERALSIEPSLTLQISAKANQLSAEGVDICNLSAGEPDFNAPKEVIEATSKAIFDGFTKYGPAAGNLDLRKAIA
NKLRIQNNLNYEFENVMVTNGAKQAIYNLFQVLLNIGDEVIIPSPYWLSYPQMVRLAGGKPIFTNSSAEDGFKIDIKDLK
SKISSKTKFIIINSPNNPTGRVMSKEELLQIADIVRENPNINILSDEIYELILKKEFKHYSISSQANDLKDRIFIINGFA
KGWAMTGWRIGYLVGPKDVIKASSALQSQSTSNVCSFVQKGALEALKINNEFFSMINSHYDQRRSLLYEGLKNINGIYIE
EPNGAFYAFPRLPNSSITSVDFCNKALQDYGLVVVPGKAFGADECIRISCATSEIKIKDGLERFKKAISKYF
>Mature_391_residues
SQVNLSERALSIEPSLTLQISAKANQLSAEGVDICNLSAGEPDFNAPKEVIEATSKAIFDGFTKYGPAAGNLDLRKAIAN
KLRIQNNLNYEFENVMVTNGAKQAIYNLFQVLLNIGDEVIIPSPYWLSYPQMVRLAGGKPIFTNSSAEDGFKIDIKDLKS
KISSKTKFIIINSPNNPTGRVMSKEELLQIADIVRENPNINILSDEIYELILKKEFKHYSISSQANDLKDRIFIINGFAK
GWAMTGWRIGYLVGPKDVIKASSALQSQSTSNVCSFVQKGALEALKINNEFFSMINSHYDQRRSLLYEGLKNINGIYIEE
PNGAFYAFPRLPNSSITSVDFCNKALQDYGLVVVPGKAFGADECIRISCATSEIKIKDGLERFKKAISKYF

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=397, Percent_Identity=27.2040302267003, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI169881279, Length=397, Percent_Identity=27.2040302267003, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI56713254, Length=316, Percent_Identity=29.746835443038, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI56713256, Length=316, Percent_Identity=29.746835443038, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI4507369, Length=377, Percent_Identity=27.3209549071618, Blast_Score=129, Evalue=6e-30,
Organism=Homo sapiens, GI169881281, Length=308, Percent_Identity=25.6493506493506, Blast_Score=108, Evalue=1e-23,
Organism=Escherichia coli, GI1786816, Length=373, Percent_Identity=27.8820375335121, Blast_Score=153, Evalue=2e-38,
Organism=Escherichia coli, GI1788627, Length=385, Percent_Identity=29.6103896103896, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1788722, Length=383, Percent_Identity=25.065274151436, Blast_Score=111, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17567663, Length=362, Percent_Identity=27.3480662983425, Blast_Score=131, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI71994476, Length=294, Percent_Identity=29.2517006802721, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI71994472, Length=294, Percent_Identity=29.2517006802721, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17567369, Length=251, Percent_Identity=31.0756972111554, Blast_Score=114, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6322401, Length=394, Percent_Identity=25.1269035532995, Blast_Score=118, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6320317, Length=311, Percent_Identity=25.4019292604502, Blast_Score=79, Evalue=9e-16,
Organism=Drosophila melanogaster, GI28573069, Length=349, Percent_Identity=26.647564469914, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24646114, Length=349, Percent_Identity=26.647564469914, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI28573067, Length=349, Percent_Identity=26.647564469914, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI28573065, Length=349, Percent_Identity=26.647564469914, Blast_Score=125, Evalue=4e-29,
Organism=Drosophila melanogaster, GI18859735, Length=378, Percent_Identity=22.2222222222222, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24641770, Length=392, Percent_Identity=22.4489795918367, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24641760, Length=392, Percent_Identity=22.4489795918367, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24641768, Length=392, Percent_Identity=22.4489795918367, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24641766, Length=392, Percent_Identity=22.4489795918367, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24641764, Length=392, Percent_Identity=22.4489795918367, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45551451, Length=392, Percent_Identity=22.4489795918367, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43547; Mature: 43416

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQVNLSERALSIEPSLTLQISAKANQLSAEGVDICNLSAGEPDFNAPKEVIEATSKAIF
CCCCCCCHHEEEECCCEEEEEECCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHH
DGFTKYGPAAGNLDLRKAIANKLRIQNNLNYEFENVMVTNGAKQAIYNLFQVLLNIGDEV
HHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEECCHHHHHHHHHHHHHHCCCCE
IIPSPYWLSYPQMVRLAGGKPIFTNSSAEDGFKIDIKDLKSKISSKTKFIIINSPNNPTG
EECCCCCCCCHHHHHHCCCCEEECCCCCCCCCEEEHHHHHHHHCCCEEEEEEECCCCCCC
RVMSKEELLQIADIVRENPNINILSDEIYELILKKEFKHYSISSQANDLKDRIFIINGFA
CCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCC
KGWAMTGWRIGYLVGPKDVIKASSALQSQSTSNVCSFVQKGALEALKINNEFFSMINSHY
CCEECCCEEEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHCCHHEEEECHHHHHHHHHHH
DQRRSLLYEGLKNINGIYIEEPNGAFYAFPRLPNSSITSVDFCNKALQDYGLVVVPGKAF
HHHHHHHHHHHHCCCCEEEECCCCCEEEECCCCCCCCCHHHHHHHHHHHCCEEEECCCCC
GADECIRISCATSEIKIKDGLERFKKAISKYF
CCCCEEEEEECCCEEEHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SQVNLSERALSIEPSLTLQISAKANQLSAEGVDICNLSAGEPDFNAPKEVIEATSKAIF
CCCCCCHHEEEECCCEEEEEECCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHHHH
DGFTKYGPAAGNLDLRKAIANKLRIQNNLNYEFENVMVTNGAKQAIYNLFQVLLNIGDEV
HHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEEEECCHHHHHHHHHHHHHHCCCCE
IIPSPYWLSYPQMVRLAGGKPIFTNSSAEDGFKIDIKDLKSKISSKTKFIIINSPNNPTG
EECCCCCCCCHHHHHHCCCCEEECCCCCCCCCEEEHHHHHHHHCCCEEEEEEECCCCCCC
RVMSKEELLQIADIVRENPNINILSDEIYELILKKEFKHYSISSQANDLKDRIFIINGFA
CCCCHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCC
KGWAMTGWRIGYLVGPKDVIKASSALQSQSTSNVCSFVQKGALEALKINNEFFSMINSHY
CCEECCCEEEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHCCHHEEEECHHHHHHHHHHH
DQRRSLLYEGLKNINGIYIEEPNGAFYAFPRLPNSSITSVDFCNKALQDYGLVVVPGKAF
HHHHHHHHHHHHCCCCEEEECCCCCEEEECCCCCCCCCHHHHHHHHHHHCCEEEECCCCC
GADECIRISCATSEIKIKDGLERFKKAISKYF
CCCCEEEEEECCCEEEHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]