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The map label for this gene is sigC [H]

Identifier: 78778962

GI number: 78778962

Start: 536074

End: 536997

Strand: Reverse

Name: sigC [H]

Synonym: PMT9312_0577

Alternate gene names: 78778962

Gene position: 536997-536074 (Counterclockwise)

Preceding gene: 78778963

Following gene: 78778961

Centisome position: 31.42

GC content: 39.5

Gene sequence:

>924_bases
GTGAGTTCATTAAGCGATTTTCTTGGTGAAATAGGTCGTCATCAACTTTTGACTCCCGAAAGAGAACTCACTATGGGCAG
AAAAGTCCAAGAAATGGTCGTGCTTGTTAATAGATGCCAAGAGGCAGGTGGGAAAGGCCCTGCTTGTGAATATTCCGAAG
CTGAAAGAAAAAAGATCAAAATTGGTGAAAAGGCCAAAAATGAGATGATCACAGCCAACCTAAGATTAGTTGTCAACCTT
GCCAAGAGATATCAAGGAAAAGGGCTAGAATTACTGGACTTGATTCAGGAGGGGACATTAGGCCTTACAAGGGCTGTCGA
AAAATATGATCCCTCTAGGGGACACAGATTCTCCACCTATGCTTATTGGTGGATCAGGCAAGGATTAAATAGAGCATTAT
CAACTCAAAGTAGGACTATCAGGATACCCGTTAATATCAATGAAAAGCTCACGAAATTAAGATCGGCTAAATCAAAGCTA
ATGCAACTTAAAGGTATTACACCCAATAGTGATGAGCTAGCTGAAGAATTAAAAATAACTAAGGAGGAAATTGATGAACT
CCTTTCTTGTGAATTAAGAAGCATCACTGTTAGTCTCCAAGGTACTGTTAAATCAAAGTCTGATCCCTCTGAACTAGTTG
ATATTCTTCCAAGTGATCAAACTCCTCCAATGGAGTTAGCCGAATTAGCTGAGAGGACAGCCTCTGCTTGGAAGTTATTA
GATAAAGCAAATTTAACTGAGAAAGAGAGAAAGATAGTAAGCCTAAGATTTGGTTTAGACGGTTCAAATGAGTGGAGAAC
TTTAGCTGAAGTAGCAAGACATATGAGTTGTAGCAGGGAATATTGCCGACAGGTTGTTCAACGTGCTTTAAGAAAACTTA
GAAAAGCAGGAATACAGAATGGCTTGGTTGATAGCATTAGCTAA

Upstream 100 bases:

>100_bases
AACTAAATAATAATTATTAATTAAATATTAATTAATTATTACATGTATGGCTTATTACTGAATTAACTATAAGTTAAATA
TATCAACAATGAGGTAAATC

Downstream 100 bases:

>100_bases
AAATATCATTAGAAATATTTAAATTTCATTTATAACGATGAAAGAGAATTACAAAAACCAAGAAAAAATTTATGATGCTG
AAGTTTTAGAAAGTTCAACA

Product: type II alternative sigma-70 family RNA polymerase sigma factor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 306

Protein sequence:

>307_residues
MSSLSDFLGEIGRHQLLTPERELTMGRKVQEMVVLVNRCQEAGGKGPACEYSEAERKKIKIGEKAKNEMITANLRLVVNL
AKRYQGKGLELLDLIQEGTLGLTRAVEKYDPSRGHRFSTYAYWWIRQGLNRALSTQSRTIRIPVNINEKLTKLRSAKSKL
MQLKGITPNSDELAEELKITKEEIDELLSCELRSITVSLQGTVKSKSDPSELVDILPSDQTPPMELAELAERTASAWKLL
DKANLTEKERKIVSLRFGLDGSNEWRTLAEVARHMSCSREYCRQVVQRALRKLRKAGIQNGLVDSIS

Sequences:

>Translated_307_residues
MSSLSDFLGEIGRHQLLTPERELTMGRKVQEMVVLVNRCQEAGGKGPACEYSEAERKKIKIGEKAKNEMITANLRLVVNL
AKRYQGKGLELLDLIQEGTLGLTRAVEKYDPSRGHRFSTYAYWWIRQGLNRALSTQSRTIRIPVNINEKLTKLRSAKSKL
MQLKGITPNSDELAEELKITKEEIDELLSCELRSITVSLQGTVKSKSDPSELVDILPSDQTPPMELAELAERTASAWKLL
DKANLTEKERKIVSLRFGLDGSNEWRTLAEVARHMSCSREYCRQVVQRALRKLRKAGIQNGLVDSIS
>Mature_306_residues
SSLSDFLGEIGRHQLLTPERELTMGRKVQEMVVLVNRCQEAGGKGPACEYSEAERKKIKIGEKAKNEMITANLRLVVNLA
KRYQGKGLELLDLIQEGTLGLTRAVEKYDPSRGHRFSTYAYWWIRQGLNRALSTQSRTIRIPVNINEKLTKLRSAKSKLM
QLKGITPNSDELAEELKITKEEIDELLSCELRSITVSLQGTVKSKSDPSELVDILPSDQTPPMELAELAERTASAWKLLD
KANLTEKERKIVSLRFGLDGSNEWRTLAEVARHMSCSREYCRQVVQRALRKLRKAGIQNGLVDSIS

Specific function: Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released [H]

COG id: COG0568

COG function: function code K; DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sigma-70 factor family [H]

Homologues:

Organism=Escherichia coli, GI1789448, Length=244, Percent_Identity=40.1639344262295, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI1789098, Length=298, Percent_Identity=37.248322147651, Blast_Score=158, Evalue=4e-40,
Organism=Escherichia coli, GI1789871, Length=243, Percent_Identity=30.4526748971193, Blast_Score=82, Evalue=5e-17,

Paralogues:

None

Copy number: 700 (log & stationary phase) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014284
- InterPro:   IPR000943
- InterPro:   IPR009042
- InterPro:   IPR007627
- InterPro:   IPR007624
- InterPro:   IPR007630
- InterPro:   IPR013325
- InterPro:   IPR013324
- InterPro:   IPR017848
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00140 Sigma70_r1_2; PF04542 Sigma70_r2; PF04539 Sigma70_r3; PF04545 Sigma70_r4 [H]

EC number: NA

Molecular weight: Translated: 34666; Mature: 34535

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLSDFLGEIGRHQLLTPERELTMGRKVQEMVVLVNRCQEAGGKGPACEYSEAERKKIK
CCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
IGEKAKNEMITANLRLVVNLAKRYQGKGLELLDLIQEGTLGLTRAVEKYDPSRGHRFSTY
CCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHCCCCCCCCCHHH
AYWWIRQGLNRALSTQSRTIRIPVNINEKLTKLRSAKSKLMQLKGITPNSDELAEELKIT
HHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCC
KEEIDELLSCELRSITVSLQGTVKSKSDPSELVDILPSDQTPPMELAELAERTASAWKLL
HHHHHHHHHCHHHHEEEEEEECCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
DKANLTEKERKIVSLRFGLDGSNEWRTLAEVARHMSCSREYCRQVVQRALRKLRKAGIQN
HHCCCCHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GLVDSIS
CCCCCCC
>Mature Secondary Structure 
SSLSDFLGEIGRHQLLTPERELTMGRKVQEMVVLVNRCQEAGGKGPACEYSEAERKKIK
CHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHH
IGEKAKNEMITANLRLVVNLAKRYQGKGLELLDLIQEGTLGLTRAVEKYDPSRGHRFSTY
CCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHCCCCCCCCCHHH
AYWWIRQGLNRALSTQSRTIRIPVNINEKLTKLRSAKSKLMQLKGITPNSDELAEELKIT
HHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCC
KEEIDELLSCELRSITVSLQGTVKSKSDPSELVDILPSDQTPPMELAELAERTASAWKLL
HHHHHHHHHCHHHHEEEEEEECCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
DKANLTEKERKIVSLRFGLDGSNEWRTLAEVARHMSCSREYCRQVVQRALRKLRKAGIQN
HHCCCCHHHHHEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GLVDSIS
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]