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The map label for this gene is yrbG [H]

Identifier: 78778953

GI number: 78778953

Start: 530371

End: 531450

Strand: Reverse

Name: yrbG [H]

Synonym: PMT9312_0568

Alternate gene names: 78778953

Gene position: 531450-530371 (Counterclockwise)

Preceding gene: 78778958

Following gene: 78778951

Centisome position: 31.09

GC content: 29.91

Gene sequence:

>1080_bases
ATGAGTGATTTTTTATTTCCAATAATAGAAATATTTTTAGGAGTTGTTTTACTTTTTGCAGGAGGAGAGTTCTTTATCCA
AGGAGCTATATATTTATCTTTGATTTTAGGAATACCTCAAATAGTTATTGGTTTAACAGTTGTTTCACTAGGTACAAGCT
CTCCTGAATTATTAGTCAGTTTAAGTTCAATTTTAAAAGGTAGTGATTCGATTGCGGCTAGCAATGTAATAGGAAGCAAT
ATCTTCAATGTTCTTGTAGTTTTAGGTATAAGCTCATTGATAACACCACTTAAGGTAAAAAGCAGGATAGTCAGAAGAGA
TGTCCCTCTATTAATGGCTATTTCTTGTGCTGTTTGGGCAATGTCATCAACAGGCTTATTAACATTGCAAGCAGGGATCT
TTCTAATATTTTGTTTAGTCTTAAATACAATATGGGAAATTAATACTATCAATGAGAAAGAAGAGGCTACAAAAGATGCT
GAACCAGAGATAGCTGAATTCAAAAATAACCATAAAGGAAAGCTAAATATTTTACTAAAGTTAATATTGGGAATATTTCT
TTTAAGCTTTGGTTCAAATATTTTAGTAAACGGTTCTCAAACTCTCGCTACTCTTTTAGGTGTAAATGAAATTGTTATTG
GTTTAACTATTGTCGCCACTGGAACATCTTTGCCAGAATTAGTAACCTCAATAATTGCAGCATTTAAAGGCAAAACAGAT
CTTGCGATTGGGAATGTAATTGGAAGCAATTTGCTCAATCAACTTCTAATTCTTGGAAGTTGTAGTATTTTTTCAGGATT
TAAAGGTTTAGTAATTGAACAAAGCCTAATAAAAGTTGACTTACCTTTTATGGTTTTAACTACCTTTGCATGCTTACCAA
TTTTTTGGAGCAAAGGAAAAATTACGAGAATTGAAGGATTTATTTTGCTTAATCTTTATATTTTTTACATTCTTGACAAG
ATACTCTTTTTGAATGAATTTAATTATCTTTCTGAATTAAGGATAGGTTTAATTTTTTACTTTTCATTACTTGTAGTAAT
TCTATTTGCTCAAGAAAATTTAAAATTTTCTGAATCATAA

Upstream 100 bases:

>100_bases
AATTTTAACAGCAAATTAAAATTGACAATAAATTATAGATATTCGAGGATAGTTATTAATCAATTATTAAAATTTTAATT
ATCTAAATAAAAGCTTGAAT

Downstream 100 bases:

>100_bases
TTTTAGCCATACATTGTCACAAATTCTTCTGAGATAGTTGGGTGCAAAGCCATAGTAGTATCAAAGTCTTTTTTTGTTAT
ACCTGCGTTTAATGCAATTG

Product: putative CaCA family sodium/calcium exchanger

Products: Na (I) [Cytoplasm]; Ca (II) [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 358

Protein sequence:

>359_residues
MSDFLFPIIEIFLGVVLLFAGGEFFIQGAIYLSLILGIPQIVIGLTVVSLGTSSPELLVSLSSILKGSDSIAASNVIGSN
IFNVLVVLGISSLITPLKVKSRIVRRDVPLLMAISCAVWAMSSTGLLTLQAGIFLIFCLVLNTIWEINTINEKEEATKDA
EPEIAEFKNNHKGKLNILLKLILGIFLLSFGSNILVNGSQTLATLLGVNEIVIGLTIVATGTSLPELVTSIIAAFKGKTD
LAIGNVIGSNLLNQLLILGSCSIFSGFKGLVIEQSLIKVDLPFMVLTTFACLPIFWSKGKITRIEGFILLNLYIFYILDK
ILFLNEFNYLSELRIGLIFYFSLLVVILFAQENLKFSES

Sequences:

>Translated_359_residues
MSDFLFPIIEIFLGVVLLFAGGEFFIQGAIYLSLILGIPQIVIGLTVVSLGTSSPELLVSLSSILKGSDSIAASNVIGSN
IFNVLVVLGISSLITPLKVKSRIVRRDVPLLMAISCAVWAMSSTGLLTLQAGIFLIFCLVLNTIWEINTINEKEEATKDA
EPEIAEFKNNHKGKLNILLKLILGIFLLSFGSNILVNGSQTLATLLGVNEIVIGLTIVATGTSLPELVTSIIAAFKGKTD
LAIGNVIGSNLLNQLLILGSCSIFSGFKGLVIEQSLIKVDLPFMVLTTFACLPIFWSKGKITRIEGFILLNLYIFYILDK
ILFLNEFNYLSELRIGLIFYFSLLVVILFAQENLKFSES
>Mature_358_residues
SDFLFPIIEIFLGVVLLFAGGEFFIQGAIYLSLILGIPQIVIGLTVVSLGTSSPELLVSLSSILKGSDSIAASNVIGSNI
FNVLVVLGISSLITPLKVKSRIVRRDVPLLMAISCAVWAMSSTGLLTLQAGIFLIFCLVLNTIWEINTINEKEEATKDAE
PEIAEFKNNHKGKLNILLKLILGIFLLSFGSNILVNGSQTLATLLGVNEIVIGLTIVATGTSLPELVTSIIAAFKGKTDL
AIGNVIGSNLLNQLLILGSCSIFSGFKGLVIEQSLIKVDLPFMVLTTFACLPIFWSKGKITRIEGFILLNLYIFYILDKI
LFLNEFNYLSELRIGLIFYFSLLVVILFAQENLKFSES

Specific function: Unknown

COG id: COG0530

COG function: function code P; Ca2+/Na+ antiporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Homo sapiens, GI300797277, Length=247, Percent_Identity=26.7206477732794, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI300797299, Length=247, Percent_Identity=26.7206477732794, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI29788987, Length=178, Percent_Identity=27.5280898876405, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI31563526, Length=167, Percent_Identity=28.1437125748503, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI1789587, Length=226, Percent_Identity=36.283185840708, Blast_Score=117, Evalue=1e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004481
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 39031; Mature: 38900

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDFLFPIIEIFLGVVLLFAGGEFFIQGAIYLSLILGIPQIVIGLTVVSLGTSSPELLVS
CCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LSSILKGSDSIAASNVIGSNIFNVLVVLGISSLITPLKVKSRIVRRDVPLLMAISCAVWA
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
MSSTGLLTLQAGIFLIFCLVLNTIWEINTINEKEEATKDAEPEIAEFKNNHKGKLNILLK
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCHHHHCCCCCCHHHHHHH
LILGIFLLSFGSNILVNGSQTLATLLGVNEIVIGLTIVATGTSLPELVTSIIAAFKGKTD
HHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHCCCCC
LAIGNVIGSNLLNQLLILGSCSIFSGFKGLVIEQSLIKVDLPFMVLTTFACLPIFWSKGK
HHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCC
ITRIEGFILLNLYIFYILDKILFLNEFNYLSELRIGLIFYFSLLVVILFAQENLKFSES
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SDFLFPIIEIFLGVVLLFAGGEFFIQGAIYLSLILGIPQIVIGLTVVSLGTSSPELLVS
CCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
LSSILKGSDSIAASNVIGSNIFNVLVVLGISSLITPLKVKSRIVRRDVPLLMAISCAVWA
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
MSSTGLLTLQAGIFLIFCLVLNTIWEINTINEKEEATKDAEPEIAEFKNNHKGKLNILLK
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCCCCHHHHCCCCCCHHHHHHH
LILGIFLLSFGSNILVNGSQTLATLLGVNEIVIGLTIVATGTSLPELVTSIIAAFKGKTD
HHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHCCCCC
LAIGNVIGSNLLNQLLILGSCSIFSGFKGLVIEQSLIKVDLPFMVLTTFACLPIFWSKGK
HHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCC
ITRIEGFILLNLYIFYILDKILFLNEFNYLSELRIGLIFYFSLLVVILFAQENLKFSES
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; Ca (II) [Cytoplasm] [C]

Specific reaction: Na (I) [Periplasm] + Ca (II) [Cytoplasm] = Na (I) [Cytoplasm] + Ca (II) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]