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The map label for this gene is dnaA

Identifier: 78778950

GI number: 78778950

Start: 526327

End: 527721

Strand: Direct

Name: dnaA

Synonym: PMT9312_0565

Alternate gene names: 78778950

Gene position: 526327-527721 (Clockwise)

Preceding gene: 78778947

Following gene: 78778952

Centisome position: 30.79

GC content: 34.41

Gene sequence:

>1395_bases
TTGCAAGCAATTAATCCTATTTGGGCGGAAGTTCAAAAATCACTACAAAAAACTTTAAGTAAGCCTTCATTTGAGACATG
GATAAGGCCTGCTAAATTTAATTGTTTTGAGAATGGCTTATTGACCTTAATCGCTCCAAATACGTTTTCCAGTGACTGGT
TAAGAAAGAATTATTGTGAAACTATCGAAAAAACTGCAAAAGAAATTTGCGGCTATGATGTAAAAGTTATTTTTAAATCT
GAAACAAATATCAACAGCTATTTAACAAATAAAGAGAACCTAGATGAAAAGAAAGTGGATCATAAAACAAAATCATTTTC
TAATAATAGCCAAGATATTTCTTCAAAAAATCGATCCAAAAAGCCTAACGGTTTAAATTTACGCTATGTCTTTAAAAGAT
TCGTTGTAGGTCCAAATAGTAGGTTGGCTCATGCCGCAGCTTTAGCGGTTGCCGAATCTCCCGGTAGAGAATTCAATCCA
TTATTTATTTGTGGTGGAGTGGGTCTTGGTAAAACTCATTTAATGCAGGCAATAGGTCATTATCGAGTAGAAATAGATCC
AGAAGCAAAAGTCAAATATGTATCTACAGAGACTTTTACTAACGACGTTATTAGTGGTATTAGGAGAGATGGAATGACGG
CTATTCGAGATAAATATAGAAATGTAGATTTGATTTTAATAGATGATATACAGTTCTTAGAAGGTAAAGAGTATACACAG
GAAGAATTTTTTCATACCTTCAACGCTCTTCACGAATCAGGAAGTCAAATAGTTATTGCAAGTGATAGACCTCCAAATCA
ATTGTCGGGAATTCAAGAGAGATTGATTTCTAGATTCTCAATGGGTATGACTGCAGATATTCAACCGCCCGACCTTGAGA
CAAGGACGGCTATTCTTCAAAAAAAGGCAGAACAAGAGAGGATGAATCTTCCAAGAGATTTAATTCAATTTATAGCAGGA
AGATTTACTTCGAATATTCGAGAATTGGAAGGGGCCTTTACTAGAGCTGTTGCATTCGCATCAATAACTGGCTTGCCAAT
GACAGTCCAATCAATTGCTCCAATGCTTGATCCAAATAGTGTTGGAGTAGTTGTTACTCCAAAACAAGTTATTAACAAAG
TGTCAGATTTCTTTAAAGTTTCTACTGATGAATTGATTAGTTCAAGTAGGAGAAAACCAGTGAGTCAAGCTAGGCAGATA
GGTATGTATCTTATGCGACAAGGAACAGATCTAAGCCTACCAAGAATTGGAGATGAATTTGGGGGCAAAGACCATACAAC
TGTTATGTATGCTATTGAACAAGTTGAAAAAAAATTATCTATTGATCCTAATATTGCAAGTCAAGTTCAAAAAATAAGAG
ATTTACTTCAAATAGATTCAAGAAAAAATTTATAA

Upstream 100 bases:

>100_bases
TGATGCTTTGTTAAATAATTTTAAATTTGTTGTGATCTTGTGATTTGATAATGTGCAATTATTAATTTCCAACTAGATTA
ATAATCTAAAGAAAAAAATT

Downstream 100 bases:

>100_bases
TTAACTATAAAATAAAATTTCTAGGATCTTGATCATATCTATGCATAAGAGGTATCTTATCGATTTCATTTTTGTCACTT
AGCAATTCAATTTTATTCAA

Product: chromosomal replication initiation protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 464; Mature: 464

Protein sequence:

>464_residues
MQAINPIWAEVQKSLQKTLSKPSFETWIRPAKFNCFENGLLTLIAPNTFSSDWLRKNYCETIEKTAKEICGYDVKVIFKS
ETNINSYLTNKENLDEKKVDHKTKSFSNNSQDISSKNRSKKPNGLNLRYVFKRFVVGPNSRLAHAAALAVAESPGREFNP
LFICGGVGLGKTHLMQAIGHYRVEIDPEAKVKYVSTETFTNDVISGIRRDGMTAIRDKYRNVDLILIDDIQFLEGKEYTQ
EEFFHTFNALHESGSQIVIASDRPPNQLSGIQERLISRFSMGMTADIQPPDLETRTAILQKKAEQERMNLPRDLIQFIAG
RFTSNIRELEGAFTRAVAFASITGLPMTVQSIAPMLDPNSVGVVVTPKQVINKVSDFFKVSTDELISSSRRKPVSQARQI
GMYLMRQGTDLSLPRIGDEFGGKDHTTVMYAIEQVEKKLSIDPNIASQVQKIRDLLQIDSRKNL

Sequences:

>Translated_464_residues
MQAINPIWAEVQKSLQKTLSKPSFETWIRPAKFNCFENGLLTLIAPNTFSSDWLRKNYCETIEKTAKEICGYDVKVIFKS
ETNINSYLTNKENLDEKKVDHKTKSFSNNSQDISSKNRSKKPNGLNLRYVFKRFVVGPNSRLAHAAALAVAESPGREFNP
LFICGGVGLGKTHLMQAIGHYRVEIDPEAKVKYVSTETFTNDVISGIRRDGMTAIRDKYRNVDLILIDDIQFLEGKEYTQ
EEFFHTFNALHESGSQIVIASDRPPNQLSGIQERLISRFSMGMTADIQPPDLETRTAILQKKAEQERMNLPRDLIQFIAG
RFTSNIRELEGAFTRAVAFASITGLPMTVQSIAPMLDPNSVGVVVTPKQVINKVSDFFKVSTDELISSSRRKPVSQARQI
GMYLMRQGTDLSLPRIGDEFGGKDHTTVMYAIEQVEKKLSIDPNIASQVQKIRDLLQIDSRKNL
>Mature_464_residues
MQAINPIWAEVQKSLQKTLSKPSFETWIRPAKFNCFENGLLTLIAPNTFSSDWLRKNYCETIEKTAKEICGYDVKVIFKS
ETNINSYLTNKENLDEKKVDHKTKSFSNNSQDISSKNRSKKPNGLNLRYVFKRFVVGPNSRLAHAAALAVAESPGREFNP
LFICGGVGLGKTHLMQAIGHYRVEIDPEAKVKYVSTETFTNDVISGIRRDGMTAIRDKYRNVDLILIDDIQFLEGKEYTQ
EEFFHTFNALHESGSQIVIASDRPPNQLSGIQERLISRFSMGMTADIQPPDLETRTAILQKKAEQERMNLPRDLIQFIAG
RFTSNIRELEGAFTRAVAFASITGLPMTVQSIAPMLDPNSVGVVVTPKQVINKVSDFFKVSTDELISSSRRKPVSQARQI
GMYLMRQGTDLSLPRIGDEFGGKDHTTVMYAIEQVEKKLSIDPNIASQVQKIRDLLQIDSRKNL

Specific function: Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box):5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phosph

COG id: COG0593

COG function: function code L; ATPase involved in DNA replication initiation

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dnaA family [H]

Homologues:

Organism=Escherichia coli, GI2367267, Length=444, Percent_Identity=37.3873873873874, Blast_Score=319, Evalue=2e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001957
- InterPro:   IPR020591
- InterPro:   IPR018312
- InterPro:   IPR013159
- InterPro:   IPR013317
- InterPro:   IPR010921 [H]

Pfam domain/function: PF00308 Bac_DnaA; PF08299 Bac_DnaA_C [H]

EC number: NA

Molecular weight: Translated: 52335; Mature: 52335

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS01008 DNAA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAINPIWAEVQKSLQKTLSKPSFETWIRPAKFNCFENGLLTLIAPNTFSSDWLRKNYCE
CCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHCCCCEEEEECCCCCHHHHHHHHHH
TIEKTAKEICGYDVKVIFKSETNINSYLTNKENLDEKKVDHKTKSFSNNSQDISSKNRSK
HHHHHHHHHCCCCEEEEEECCCCCHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHCCCCC
KPNGLNLRYVFKRFVVGPNSRLAHAAALAVAESPGREFNPLFICGGVGLGKTHLMQAIGH
CCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHCC
YRVEIDPEAKVKYVSTETFTNDVISGIRRDGMTAIRDKYRNVDLILIDDIQFLEGKEYTQ
EEEEECCCCCEEEEEHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEECCCHHHCCCCHHH
EEFFHTFNALHESGSQIVIASDRPPNQLSGIQERLISRFSMGMTADIQPPDLETRTAILQ
HHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
KKAEQERMNLPRDLIQFIAGRFTSNIRELEGAFTRAVAFASITGLPMTVQSIAPMLDPNS
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHCCCCCCCC
VGVVVTPKQVINKVSDFFKVSTDELISSSRRKPVSQARQIGMYLMRQGTDLSLPRIGDEF
CEEEECHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHH
GGKDHTTVMYAIEQVEKKLSIDPNIASQVQKIRDLLQIDSRKNL
CCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MQAINPIWAEVQKSLQKTLSKPSFETWIRPAKFNCFENGLLTLIAPNTFSSDWLRKNYCE
CCCCCHHHHHHHHHHHHHHCCCCHHHHCCCCCCCHHCCCCEEEEECCCCCHHHHHHHHHH
TIEKTAKEICGYDVKVIFKSETNINSYLTNKENLDEKKVDHKTKSFSNNSQDISSKNRSK
HHHHHHHHHCCCCEEEEEECCCCCHHHHCCCCCCCHHHHHHHHHHCCCCCHHHHHCCCCC
KPNGLNLRYVFKRFVVGPNSRLAHAAALAVAESPGREFNPLFICGGVGLGKTHLMQAIGH
CCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHCC
YRVEIDPEAKVKYVSTETFTNDVISGIRRDGMTAIRDKYRNVDLILIDDIQFLEGKEYTQ
EEEEECCCCCEEEEEHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEECCCHHHCCCCHHH
EEFFHTFNALHESGSQIVIASDRPPNQLSGIQERLISRFSMGMTADIQPPDLETRTAILQ
HHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHH
KKAEQERMNLPRDLIQFIAGRFTSNIRELEGAFTRAVAFASITGLPMTVQSIAPMLDPNS
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHCCCCCCCC
VGVVVTPKQVINKVSDFFKVSTDELISSSRRKPVSQARQIGMYLMRQGTDLSLPRIGDEF
CEEEECHHHHHHHHHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHH
GGKDHTTVMYAIEQVEKKLSIDPNIASQVQKIRDLLQIDSRKNL
CCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA