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The map label for this gene is gpmB [H]

Identifier: 78778900

GI number: 78778900

Start: 480164

End: 481492

Strand: Reverse

Name: gpmB [H]

Synonym: PMT9312_0515

Alternate gene names: 78778900

Gene position: 481492-480164 (Counterclockwise)

Preceding gene: 78778905

Following gene: 78778894

Centisome position: 28.17

GC content: 31.3

Gene sequence:

>1329_bases
ATGACTATAAGATTAGTTTTGGTTAGGCATGGACTAAGTAGTTTCAATGCAAAAGGATTAATTCAAGGACGGACAGATGA
TTCATTATTAACTGATGAAGGATACGAACAAGCACTCAAAGCAGGAAAAGCATTATCAAAAATAAACTTCGATAAAATCT
ATTCGTCACCTCTCGTGAGAGCTGCAGAGACTGCGAAAACAATTAAAGAAAGCTTCAACAAAGAACAAGAAATTACATTC
GATAATAATTTGTTAGAGGTAGACCTTAGTGAATGGTCTGGTATAAAAATTGATGAAATAAAAAACAAATTTCCAGAAAT
TTATCCTATTTGGAAAAATGATCCAGAAAATCTTATTTTAAAAAGAAGTGACGGTAAAACATATAAACCAATTCAAGATT
TATTTGAACAAGCAACAAATTTTTTAGAAAATATTTTGAGAATTTATTTAGACAAAGATGATGTAAATATTTTAGTAGTT
GGGCATAATGCAATTCTAAGATGTTTAATCCTTTTGTCATTGGGAAAGCCTACCCAAGGCTTTAGAAAAATAAGATTAGA
GAATGCTTCTTTTTCAATTCTCAATCTTTCAATTCATGGTAAATCTTTTAACACACAAATTGAATGTTTAAATCAAACAT
CTCATCTTAATAAAAACATTCCCAATCAAATTGGAGATTCAAGAATTTTCCTAATAAGGCATGGTGAAACAAACTGGAAC
AAAGAAGGTAGATTCCAAGGCCAAATTGATATCCCACTAAACGAAAACGGTAAAGATCAAGCGAGAAAGACTTTTGAATA
TTTGAGAAATATTTCTTTCAATAAGGCATTTTCAAGTTCAATGGATAGGCCTTACGAGACTGCACAAATAATTGTTCAAA
ATAATAAAGATTTAAAAATAGAAAAAATAGATTCACTTGTAGAAATTAGTCACGGATTATGGGAGGGTAAACTGGAATCA
GAAATCAGAGAAAAGTGGCCTGTTTTGCTAAAAAATTGGCATGATAAACCTGAAGAAGTAATAATGCCCGAAGGGGAATC
TATAAAAGATGTATCAGAAAGGTCCATAGAAGCTTTTGACAAAATTTGTCTATCTCAAAAAGATAATGATTTAAGCCTTG
TAGTCGCTCATGATGCAGTCAATAAAACTCTGATTTGCAATATACTTGGGATTAATTATTCAAATATCTGGATGATAAAA
CAAGGTAATGGTGGCATAACTATAATTGACATTTTTAAAGATCCCAGTAAAGCCCCTGTAATTAGTGCTCTAAATATCAC
AACTCATCTAGGAGGTGTCATTGATTCAACTGCTTCTGGAGCGCTTTAA

Upstream 100 bases:

>100_bases
TAAAATTATAGTTAGTTTTCATTGAAATCTCTAATATTGATATACCTATTTTTATCACGCCATGAGATGATTAAATTATA
ATCATTCTCAAATTTATATA

Downstream 100 bases:

>100_bases
ATTAAAACGCTTTTTAAAAAATTATTTTGATACAGTCAGATTTAAAATAAAGGCTTTAATTATTAAAAAAGCCAGCTTTA
CTAAGAGGCCAAAATCTTAA

Product: putative alpha-ribazole-5'-P phosphatase

Products: NA

Alternate protein names: PGAM; Phosphoglyceromutase [H]

Number of amino acids: Translated: 442; Mature: 441

Protein sequence:

>442_residues
MTIRLVLVRHGLSSFNAKGLIQGRTDDSLLTDEGYEQALKAGKALSKINFDKIYSSPLVRAAETAKTIKESFNKEQEITF
DNNLLEVDLSEWSGIKIDEIKNKFPEIYPIWKNDPENLILKRSDGKTYKPIQDLFEQATNFLENILRIYLDKDDVNILVV
GHNAILRCLILLSLGKPTQGFRKIRLENASFSILNLSIHGKSFNTQIECLNQTSHLNKNIPNQIGDSRIFLIRHGETNWN
KEGRFQGQIDIPLNENGKDQARKTFEYLRNISFNKAFSSSMDRPYETAQIIVQNNKDLKIEKIDSLVEISHGLWEGKLES
EIREKWPVLLKNWHDKPEEVIMPEGESIKDVSERSIEAFDKICLSQKDNDLSLVVAHDAVNKTLICNILGINYSNIWMIK
QGNGGITIIDIFKDPSKAPVISALNITTHLGGVIDSTASGAL

Sequences:

>Translated_442_residues
MTIRLVLVRHGLSSFNAKGLIQGRTDDSLLTDEGYEQALKAGKALSKINFDKIYSSPLVRAAETAKTIKESFNKEQEITF
DNNLLEVDLSEWSGIKIDEIKNKFPEIYPIWKNDPENLILKRSDGKTYKPIQDLFEQATNFLENILRIYLDKDDVNILVV
GHNAILRCLILLSLGKPTQGFRKIRLENASFSILNLSIHGKSFNTQIECLNQTSHLNKNIPNQIGDSRIFLIRHGETNWN
KEGRFQGQIDIPLNENGKDQARKTFEYLRNISFNKAFSSSMDRPYETAQIIVQNNKDLKIEKIDSLVEISHGLWEGKLES
EIREKWPVLLKNWHDKPEEVIMPEGESIKDVSERSIEAFDKICLSQKDNDLSLVVAHDAVNKTLICNILGINYSNIWMIK
QGNGGITIIDIFKDPSKAPVISALNITTHLGGVIDSTASGAL
>Mature_441_residues
TIRLVLVRHGLSSFNAKGLIQGRTDDSLLTDEGYEQALKAGKALSKINFDKIYSSPLVRAAETAKTIKESFNKEQEITFD
NNLLEVDLSEWSGIKIDEIKNKFPEIYPIWKNDPENLILKRSDGKTYKPIQDLFEQATNFLENILRIYLDKDDVNILVVG
HNAILRCLILLSLGKPTQGFRKIRLENASFSILNLSIHGKSFNTQIECLNQTSHLNKNIPNQIGDSRIFLIRHGETNWNK
EGRFQGQIDIPLNENGKDQARKTFEYLRNISFNKAFSSSMDRPYETAQIIVQNNKDLKIEKIDSLVEISHGLWEGKLESE
IREKWPVLLKNWHDKPEEVIMPEGESIKDVSERSIEAFDKICLSQKDNDLSLVVAHDAVNKTLICNILGINYSNIWMIKQ
GNGGITIIDIFKDPSKAPVISALNITTHLGGVIDSTASGAL

Specific function: Converts N1-(5-Phospho-Alpha-D-Ribosyl)-5,6- Dimethylbenzimidazole Into N1-Alpha-D-Ribosyl-5,6- Dimethylbenzimidazole; Involved In The Assembly Of The Nucleotide Loop Of Cobalamin. [C]

COG id: COG0406

COG function: function code G; Fructose-2,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. GpmB subfamily [H]

Homologues:

Organism=Homo sapiens, GI9966849, Length=137, Percent_Identity=35.036496350365, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI1786857, Length=184, Percent_Identity=27.1739130434783, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1790856, Length=168, Percent_Identity=32.1428571428571, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR023086 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 50033; Mature: 49902

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIRLVLVRHGLSSFNAKGLIQGRTDDSLLTDEGYEQALKAGKALSKINFDKIYSSPLVR
CEEEEEEEECCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHCCHHHH
AAETAKTIKESFNKEQEITFDNNLLEVDLSEWSGIKIDEIKNKFPEIYPIWKNDPENLIL
HHHHHHHHHHHCCCCCCEEECCCEEEEECCCCCCCCHHHHHHCCCCEEECCCCCCCCEEE
KRSDGKTYKPIQDLFEQATNFLENILRIYLDKDDVNILVVGHNAILRCLILLSLGKPTQG
ECCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCEEEEECCHHHHHHHHHHHCCCCCCC
FRKIRLENASFSILNLSIHGKSFNTQIECLNQTSHLNKNIPNQIGDSRIFLIRHGETNWN
HHEEEECCCCEEEEEEEEECCCCCCCEEEECHHHHHCCCCCHHCCCCEEEEEECCCCCCC
KEGRFQGQIDIPLNENGKDQARKTFEYLRNISFNKAFSSSMDRPYETAQIIVQNNKDLKI
CCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCCEEEEEEECCCCCCH
EKIDSLVEISHGLWEGKLESEIREKWPVLLKNWHDKPEEVIMPEGESIKDVSERSIEAFD
HHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHCCCCCCCCEECCCCCCHHHHHHHHHHHHH
KICLSQKDNDLSLVVAHDAVNKTLICNILGINYSNIWMIKQGNGGITIIDIFKDPSKAPV
HHHHCCCCCCEEEEEEECCCCCEEEEEEEECCCCEEEEEEECCCCEEEEEEECCCCCCCE
ISALNITTHLGGVIDSTASGAL
EEEEEHHHHHCCHHCCCCCCCC
>Mature Secondary Structure 
TIRLVLVRHGLSSFNAKGLIQGRTDDSLLTDEGYEQALKAGKALSKINFDKIYSSPLVR
EEEEEEEECCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHCCHHHH
AAETAKTIKESFNKEQEITFDNNLLEVDLSEWSGIKIDEIKNKFPEIYPIWKNDPENLIL
HHHHHHHHHHHCCCCCCEEECCCEEEEECCCCCCCCHHHHHHCCCCEEECCCCCCCCEEE
KRSDGKTYKPIQDLFEQATNFLENILRIYLDKDDVNILVVGHNAILRCLILLSLGKPTQG
ECCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCEEEEECCHHHHHHHHHHHCCCCCCC
FRKIRLENASFSILNLSIHGKSFNTQIECLNQTSHLNKNIPNQIGDSRIFLIRHGETNWN
HHEEEECCCCEEEEEEEEECCCCCCCEEEECHHHHHCCCCCHHCCCCEEEEEECCCCCCC
KEGRFQGQIDIPLNENGKDQARKTFEYLRNISFNKAFSSSMDRPYETAQIIVQNNKDLKI
CCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCCCCCEEEEEEECCCCCCH
EKIDSLVEISHGLWEGKLESEIREKWPVLLKNWHDKPEEVIMPEGESIKDVSERSIEAFD
HHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHCCCCCCCCEECCCCCCHHHHHHHHHHHHH
KICLSQKDNDLSLVVAHDAVNKTLICNILGINYSNIWMIKQGNGGITIIDIFKDPSKAPV
HHHHCCCCCCEEEEEEECCCCCEEEEEEEECCCCEEEEEEECCCCEEEEEEECCCCCCCE
ISALNITTHLGGVIDSTASGAL
EEEEEHHHHHCCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA