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The map label for this gene is ubiA

Identifier: 78778841

GI number: 78778841

Start: 430786

End: 431694

Strand: Reverse

Name: ubiA

Synonym: PMT9312_0456

Alternate gene names: 78778841

Gene position: 431694-430786 (Counterclockwise)

Preceding gene: 78778843

Following gene: 78778840

Centisome position: 25.26

GC content: 30.36

Gene sequence:

>909_bases
ATGAAATATACAATAGGTTATATGCAAAATAAAAATCGAGAAATTAAATTAAGTACTTTTTTTGAATTATTAAGATGGAA
TAAGCCGACTGGGAGAATGATCTTACTTATTCCTGCTGGATGGAGTTTATATTTAACACCAGATGCTAATCCAACATTAT
TAATGTTGTTAAGAATAATCCTAGGAGGACTACTAGTAAGTGGATTAGGCTGCGTGGTTAATGATATTTGGGATAAAAAA
ATTGATCAAAGAGTTTTTAGGACAAAAAATAGACCTCTAGCTGCAAATAAAATCGGTCTTAAAGCGGCTTATTTAATTCT
TTTCTTTTTAATTTTATGTAGTTTCTTTTTAACTTTGTCACTACCTCAACCTGGAAGGCTCCTTTCCATTTCACTTGCTT
TTTTAGCTTTACCTATTATTTTAATTTATCCTTCTGCCAAAAGATGGTTTAAATATCCTCAATTAATTTTATCCATATGC
TGGGGTTTTGCTGTCTTAATTCCCTGGGCAGCAAATGAAGGCAATTTGAATAGTATTGTTTTATTGTTTTGCTGGCTAGC
TACTATTTTTTGGACTTTTGGCTTTGACACGATTTATGCTTTAGCAGATAAAAAATATGATATCAAAATTGGAATAAATA
GTTCCGCTGTTAACCTCCAGAACAATACAAGAATAACTATTCAAATTTGTTATTTTTTAACTTCTAGTTTTCTCGCATTA
TGCGGATTTATTAATCAAATGGATTTTATTTTTTGGCCAATTTGGCTTACAACGTCAATCTTAATGCAGAGAGATATACT
AAAGGTATTTCCTGAGGAAAAGCAATCAATAAAAAATATTGGGAATCACTTCAAAAATCAATCAATTTATGGAGGAGTCC
TTTTATTAGGAATCATTATTGCCTCATAA

Upstream 100 bases:

>100_bases
GTTTATAAGATGCAGATATCTTGAATCCATTAATAAATATACTCAAGATTGATTATTAAATAATAGGAATCACTTAATCC
TAGTAAGATTATTTAAAGTT

Downstream 100 bases:

>100_bases
ATTCTAAATATGGTTTTTAGATTAAAAAAAGGTGATCTAATCGATATTGTAGCTCCAGGCTCCTTTATTGATGAAGAAGA
AAATTTTCAAAAAGGCATAG

Product: prenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MKYTIGYMQNKNREIKLSTFFELLRWNKPTGRMILLIPAGWSLYLTPDANPTLLMLLRIILGGLLVSGLGCVVNDIWDKK
IDQRVFRTKNRPLAANKIGLKAAYLILFFLILCSFFLTLSLPQPGRLLSISLAFLALPIILIYPSAKRWFKYPQLILSIC
WGFAVLIPWAANEGNLNSIVLLFCWLATIFWTFGFDTIYALADKKYDIKIGINSSAVNLQNNTRITIQICYFLTSSFLAL
CGFINQMDFIFWPIWLTTSILMQRDILKVFPEEKQSIKNIGNHFKNQSIYGGVLLLGIIIAS

Sequences:

>Translated_302_residues
MKYTIGYMQNKNREIKLSTFFELLRWNKPTGRMILLIPAGWSLYLTPDANPTLLMLLRIILGGLLVSGLGCVVNDIWDKK
IDQRVFRTKNRPLAANKIGLKAAYLILFFLILCSFFLTLSLPQPGRLLSISLAFLALPIILIYPSAKRWFKYPQLILSIC
WGFAVLIPWAANEGNLNSIVLLFCWLATIFWTFGFDTIYALADKKYDIKIGINSSAVNLQNNTRITIQICYFLTSSFLAL
CGFINQMDFIFWPIWLTTSILMQRDILKVFPEEKQSIKNIGNHFKNQSIYGGVLLLGIIIAS
>Mature_302_residues
MKYTIGYMQNKNREIKLSTFFELLRWNKPTGRMILLIPAGWSLYLTPDANPTLLMLLRIILGGLLVSGLGCVVNDIWDKK
IDQRVFRTKNRPLAANKIGLKAAYLILFFLILCSFFLTLSLPQPGRLLSISLAFLALPIILIYPSAKRWFKYPQLILSIC
WGFAVLIPWAANEGNLNSIVLLFCWLATIFWTFGFDTIYALADKKYDIKIGINSSAVNLQNNTRITIQICYFLTSSFLAL
CGFINQMDFIFWPIWLTTSILMQRDILKVFPEEKQSIKNIGNHFKNQSIYGGVLLLGIIIAS

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=210, Percent_Identity=33.8095238095238, Blast_Score=123, Evalue=2e-28,
Organism=Escherichia coli, GI1790473, Length=290, Percent_Identity=32.4137931034483, Blast_Score=132, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17553718, Length=288, Percent_Identity=30.2083333333333, Blast_Score=127, Evalue=7e-30,
Organism=Caenorhabditis elegans, GI32565247, Length=289, Percent_Identity=30.7958477508651, Blast_Score=118, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17553720, Length=345, Percent_Identity=26.3768115942029, Blast_Score=101, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI32565245, Length=143, Percent_Identity=34.2657342657343, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI32565243, Length=143, Percent_Identity=34.2657342657343, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324370, Length=228, Percent_Identity=32.0175438596491, Blast_Score=114, Evalue=2e-26,
Organism=Drosophila melanogaster, GI21355567, Length=285, Percent_Identity=28.7719298245614, Blast_Score=131, Evalue=7e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 34465; Mature: 34465

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYTIGYMQNKNREIKLSTFFELLRWNKPTGRMILLIPAGWSLYLTPDANPTLLMLLRII
CCEEEEECCCCCCEEEHHHHHHHHHCCCCCCCEEEEEECCCEEEECCCCCHHHHHHHHHH
LGGLLVSGLGCVVNDIWDKKIDQRVFRTKNRPLAANKIGLKAAYLILFFLILCSFFLTLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
LPQPGRLLSISLAFLALPIILIYPSAKRWFKYPQLILSICWGFAVLIPWAANEGNLNSIV
CCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
LLFCWLATIFWTFGFDTIYALADKKYDIKIGINSSAVNLQNNTRITIQICYFLTSSFLAL
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEECCCCEEEEEEHHHHHHHHHHH
CGFINQMDFIFWPIWLTTSILMQRDILKVFPEEKQSIKNIGNHFKNQSIYGGVLLLGIII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
AS
CC
>Mature Secondary Structure
MKYTIGYMQNKNREIKLSTFFELLRWNKPTGRMILLIPAGWSLYLTPDANPTLLMLLRII
CCEEEEECCCCCCEEEHHHHHHHHHCCCCCCCEEEEEECCCEEEECCCCCHHHHHHHHHH
LGGLLVSGLGCVVNDIWDKKIDQRVFRTKNRPLAANKIGLKAAYLILFFLILCSFFLTLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
LPQPGRLLSISLAFLALPIILIYPSAKRWFKYPQLILSICWGFAVLIPWAANEGNLNSIV
CCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHH
LLFCWLATIFWTFGFDTIYALADKKYDIKIGINSSAVNLQNNTRITIQICYFLTSSFLAL
HHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEECCCCEEEEEEHHHHHHHHHHH
CGFINQMDFIFWPIWLTTSILMQRDILKVFPEEKQSIKNIGNHFKNQSIYGGVLLLGIII
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
AS
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA