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The map label for this gene is phoQ [C]

Identifier: 78778656

GI number: 78778656

Start: 259288

End: 260424

Strand: Direct

Name: phoQ [C]

Synonym: PMT9312_0271

Alternate gene names: 78778656

Gene position: 259288-260424 (Clockwise)

Preceding gene: 78778654

Following gene: 78778658

Centisome position: 15.17

GC content: 32.81

Gene sequence:

>1137_bases
ATGAATCTCTCAAAAAAATTTGAAGAACTAGTCATAAAACAGCTAGAGAGTTTTGGTTGCTCAATGGGAGTTACTCATTT
AGTTATGTATCTTGCTTCAGCTAACCAAGGAACTAAAGCATCTTTTGAAATGATTGGTCAATGGCCACAAATTGATAGGC
TTCTAATATCAATAGAAGATGATCCTTCACTCAAAGTTTCTTCTCCTAATAGAAGATGGTACCCGCTTCAAGAAAACGAT
ATTCTACTTGGTGTCCTTAGGGTAGAAACTGATTTGAAAGGGGGGAATTGGCCAGTATCTCTTGATTCTAGATTAAAAGC
ACTATCAATATCTTTAGCTAAATGCGTTTCTATCGAATTAGAACGTCAAAATAAAAATGAAGAAATCAATTATTTAAAAA
ATCAGGTCAATGTCATAATCCATCAATTGAGGAATCCATTGGCTGCTCTCAGGACATATGCAAAATTACTAATAAAAAAA
CTTGGTTCAGATGATGATTCTATTGAGATAGTCGAACGCATGATAATAGAGCAAAAACAAATTAATCAATATATGGACTC
TTTTGCGAAATTAAATACATCTATTCAACTTCCTTTAGAAATTGGAGAAGAAAGATTATTATTACCACCAAATTTAGATA
ATAATAAGGTAATAACTGTTCAGAGTTTATTGAGGCCAATTTTAGAAAGGGGTAAAGCTAATGCGAACTTAGAGAATAGA
GATTGGACTGAACCTTCTCTTTGGCCACGTTGGACTTTATCGCCATTAAAGGCAAAATATGCTGTAATTGCTGAAATTGT
GGCTAATTTATTAGAAAATGCGTTTAAATATGCCCAACAAGATGCTGAGATTGGACTCACCATTACGAGTAAAGGTATGT
GCATATTTGATGATGGAAAAAAAATAACCAAAAATGAAAATGAGAAGATTTTTCAAAAAGGCTTTAGAGGATCTGCCGCT
AAGAAGAAGGATGGTACTGGTGTGGGACTTTTTTTAGCGAGAAAATTAGCAAAACAAATTGGAGGAGAGTTGAGATTGCT
GGAAAATTACTCAATTGATAATACTGAGGAATTAAAAAATCTTAAGAAGAAAAATATTTTCTACTTAGAGCTTCCTATAA
AAGAATTGAATGCATAA

Upstream 100 bases:

>100_bases
CTGGCTAAAGTCAGACCTCTTTATATATCTTAATACTTTTTTCATATTTTACAAGCCCTTTTCAAATTTTTTCTAAAAAT
TTCTCAAAATTTTATTAGTT

Downstream 100 bases:

>100_bases
ATAACATTGCAGTTTCAACAAGTACAACACTCGCACCACAGGCATCTCCATTGAAGCCTCCAATTTTATTACCCAGCATG
TTTGGAATAGAATAACTTAA

Product: two-component sensor histidine kinase

Products: Phosphorylated phoP [C]

Alternate protein names: Histidine Kinase; GAF Sensor Signal Transduction Histidine Kinase; Two-Component System Sensor Histidine Kinase; Sensory Transduction Histidine Kinase; Signal Transduction Histidine Kinase

Number of amino acids: Translated: 378; Mature: 378

Protein sequence:

>378_residues
MNLSKKFEELVIKQLESFGCSMGVTHLVMYLASANQGTKASFEMIGQWPQIDRLLISIEDDPSLKVSSPNRRWYPLQEND
ILLGVLRVETDLKGGNWPVSLDSRLKALSISLAKCVSIELERQNKNEEINYLKNQVNVIIHQLRNPLAALRTYAKLLIKK
LGSDDDSIEIVERMIIEQKQINQYMDSFAKLNTSIQLPLEIGEERLLLPPNLDNNKVITVQSLLRPILERGKANANLENR
DWTEPSLWPRWTLSPLKAKYAVIAEIVANLLENAFKYAQQDAEIGLTITSKGMCIFDDGKKITKNENEKIFQKGFRGSAA
KKKDGTGVGLFLARKLAKQIGGELRLLENYSIDNTEELKNLKKKNIFYLELPIKELNA

Sequences:

>Translated_378_residues
MNLSKKFEELVIKQLESFGCSMGVTHLVMYLASANQGTKASFEMIGQWPQIDRLLISIEDDPSLKVSSPNRRWYPLQEND
ILLGVLRVETDLKGGNWPVSLDSRLKALSISLAKCVSIELERQNKNEEINYLKNQVNVIIHQLRNPLAALRTYAKLLIKK
LGSDDDSIEIVERMIIEQKQINQYMDSFAKLNTSIQLPLEIGEERLLLPPNLDNNKVITVQSLLRPILERGKANANLENR
DWTEPSLWPRWTLSPLKAKYAVIAEIVANLLENAFKYAQQDAEIGLTITSKGMCIFDDGKKITKNENEKIFQKGFRGSAA
KKKDGTGVGLFLARKLAKQIGGELRLLENYSIDNTEELKNLKKKNIFYLELPIKELNA
>Mature_378_residues
MNLSKKFEELVIKQLESFGCSMGVTHLVMYLASANQGTKASFEMIGQWPQIDRLLISIEDDPSLKVSSPNRRWYPLQEND
ILLGVLRVETDLKGGNWPVSLDSRLKALSISLAKCVSIELERQNKNEEINYLKNQVNVIIHQLRNPLAALRTYAKLLIKK
LGSDDDSIEIVERMIIEQKQINQYMDSFAKLNTSIQLPLEIGEERLLLPPNLDNNKVITVQSLLRPILERGKANANLENR
DWTEPSLWPRWTLSPLKAKYAVIAEIVANLLENAFKYAQQDAEIGLTITSKGMCIFDDGKKITKNENEKIFQKGFRGSAA
KKKDGTGVGLFLARKLAKQIGGELRLLENYSIDNTEELKNLKKKNIFYLELPIKELNA

Specific function: Member Of The Two-Component Regulatory System Phoq/Phop Involved In The Regulation Of Acid Phosphatase. Phoq May Function As A Membrane-Associated Protein Kinase That Phosphorylates Phop In Response To Environmental Signals. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.3.- [C]

Molecular weight: Translated: 42924; Mature: 42924

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLSKKFEELVIKQLESFGCSMGVTHLVMYLASANQGTKASFEMIGQWPQIDRLLISIED
CCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHCCCCCCCEEEEEECC
DPSLKVSSPNRRWYPLQENDILLGVLRVETDLKGGNWPVSLDSRLKALSISLAKCVSIEL
CCCEEECCCCCEECCCCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHEEEE
ERQNKNEEINYLKNQVNVIIHQLRNPLAALRTYAKLLIKKLGSDDDSIEIVERMIIEQKQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
INQYMDSFAKLNTSIQLPLEIGEERLLLPPNLDNNKVITVQSLLRPILERGKANANLENR
HHHHHHHHHHCCCCEEEEHCCCCCEEEECCCCCCCEEEEHHHHHHHHHHCCCCCCCCCCC
DWTEPSLWPRWTLSPLKAKYAVIAEIVANLLENAFKYAQQDAEIGLTITSKGMCIFDDGK
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEECCC
KITKNENEKIFQKGFRGSAAKKKDGTGVGLFLARKLAKQIGGELRLLENYSIDNTEELKN
CCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHH
LKKKNIFYLELPIKELNA
HHHCCEEEEEECHHHHCC
>Mature Secondary Structure
MNLSKKFEELVIKQLESFGCSMGVTHLVMYLASANQGTKASFEMIGQWPQIDRLLISIED
CCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCHHHHHHCCCCCCCEEEEEECC
DPSLKVSSPNRRWYPLQENDILLGVLRVETDLKGGNWPVSLDSRLKALSISLAKCVSIEL
CCCEEECCCCCEECCCCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHEEEE
ERQNKNEEINYLKNQVNVIIHQLRNPLAALRTYAKLLIKKLGSDDDSIEIVERMIIEQKQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
INQYMDSFAKLNTSIQLPLEIGEERLLLPPNLDNNKVITVQSLLRPILERGKANANLENR
HHHHHHHHHHCCCCEEEEHCCCCCEEEECCCCCCCEEEEHHHHHHHHHHCCCCCCCCCCC
DWTEPSLWPRWTLSPLKAKYAVIAEIVANLLENAFKYAQQDAEIGLTITSKGMCIFDDGK
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEECCC
KITKNENEKIFQKGFRGSAAKKKDGTGVGLFLARKLAKQIGGELRLLENYSIDNTEELKN
CCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHH
LKKKNIFYLELPIKELNA
HHHCCEEEEEECHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: phoP [C]

Specific reaction: phoP = Phosphorylated phoP [C]

General reaction: Phosphorylation [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA