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The map label for this gene is ispH [H]

Identifier: 78778651

GI number: 78778651

Start: 254602

End: 255798

Strand: Direct

Name: ispH [H]

Synonym: PMT9312_0266

Alternate gene names: 78778651

Gene position: 254602-255798 (Clockwise)

Preceding gene: 78778650

Following gene: 78778652

Centisome position: 14.9

GC content: 33.08

Gene sequence:

>1197_bases
ATGGATACTCAAGCTTTTAGAAGATCTCTGCATCATTCTGACAGATATAATAGAAGGGGTTTCGATTCTCCAACAAAAAG
AGCTCAAGCTTTAGAAGAAGCTTATCAAAGTGATTTGATAAGTTCTATAAGAGATAATGGTTTTACCTACAACAAAGGCC
GACTAAATATTAAATTGGCCAAAGCCTTTGGTTTCTGTTGGGGAGTTGAAAGAGCTGTAGCAATGGCATATGAAACTCGG
AGACATTACCCTAATGAGAATATTTGGATAACAAACGAAATAATTCATAACCCTTCTGTTAATGATCATTTGAGAAAAAT
GAATGTAAAGTTCATTTCAGCTAAAAATGGAATTAAGGATTTTTCGTTAGTTTCTAATGGGGATGTAGTTATATTGCCTG
CTTTTGGAGCTACTGTTCAAGAAATGAAACTCCTTCATGAGAAAGGATGTCATATTATAGATACAACTTGTCCTTGGGTT
TCTAAGGTTTGGCATACTGTCGAGAAACATAAAAAGCATGTTTTTACATCTATTATTCATGGAAAATTTAAGCATGAAGA
GACTCTTGCTACCAGCTCATTTGCAGGTAAATATTTAGTTGTACTTGATCTAGAAGAAGCAAATTATATATCTGAGTATA
TTCTGGGCAGAGGAAACAGAAATGAGTTTATGAACAAATTTGCTAAAGCTTGTTCTGATGGATTTGATCCCGATAAAGAT
TTAGATAGAGTGGGAGTTGCTAACCAGACAACTATGCTTAAGAGTGAGACTGAGGAAATTGGAAAGGTTTTTGAAAAAAC
GATGTTAAAAAAATTTGGACCAGAAAATCTAAATAGTCACTTTTTAGCATTTAATACAATTTGTGATGCAACTGAAGAAA
GGCAAGATGCAATGTTTTCTTTGGTTGATGAAGACCTTGATATTCTAGTAGTTATAGGCGGCTTTAATTCTTCAAACACT
ACTCATTTACAAGAAATAGCAATTACTAAAAATATTACTTCTTTTCACATAGATACCCCAGAGAGGATATCAGTTGAAGA
AAACTCGATATTACATAAACCACTAGGATTAGATTTAGAACTTAAAAATAATTTTTTACCTAGTGGAAATATTAATGTCG
GAATTACATCAGGTGCATCTACTCCTGATAAAGTTGTTGCGGATGTTATAGAAAAGTTGACTGTTATAGCTTCTTGA

Upstream 100 bases:

>100_bases
CTGCTAAATAATCTAACTTAAAATTAATTTTAGAAACCTGACTTATGTCAGGTTTCTTTTTTTTTACAAAAAATTATTTA
AAATGTTGTAATATTTAAAG

Downstream 100 bases:

>100_bases
AGTTGCAACGTTATTTATAAATATGCTTAGTTTTTTTAATTTATTACTCATATCTTTCCAAAAGATCTACTTTATTAACT
AGAATAATTAAAAATTCATG

Product: 4-hydroxy-3-methylbut-2-enyl diphosphate reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MDTQAFRRSLHHSDRYNRRGFDSPTKRAQALEEAYQSDLISSIRDNGFTYNKGRLNIKLAKAFGFCWGVERAVAMAYETR
RHYPNENIWITNEIIHNPSVNDHLRKMNVKFISAKNGIKDFSLVSNGDVVILPAFGATVQEMKLLHEKGCHIIDTTCPWV
SKVWHTVEKHKKHVFTSIIHGKFKHEETLATSSFAGKYLVVLDLEEANYISEYILGRGNRNEFMNKFAKACSDGFDPDKD
LDRVGVANQTTMLKSETEEIGKVFEKTMLKKFGPENLNSHFLAFNTICDATEERQDAMFSLVDEDLDILVVIGGFNSSNT
THLQEIAITKNITSFHIDTPERISVEENSILHKPLGLDLELKNNFLPSGNINVGITSGASTPDKVVADVIEKLTVIAS

Sequences:

>Translated_398_residues
MDTQAFRRSLHHSDRYNRRGFDSPTKRAQALEEAYQSDLISSIRDNGFTYNKGRLNIKLAKAFGFCWGVERAVAMAYETR
RHYPNENIWITNEIIHNPSVNDHLRKMNVKFISAKNGIKDFSLVSNGDVVILPAFGATVQEMKLLHEKGCHIIDTTCPWV
SKVWHTVEKHKKHVFTSIIHGKFKHEETLATSSFAGKYLVVLDLEEANYISEYILGRGNRNEFMNKFAKACSDGFDPDKD
LDRVGVANQTTMLKSETEEIGKVFEKTMLKKFGPENLNSHFLAFNTICDATEERQDAMFSLVDEDLDILVVIGGFNSSNT
THLQEIAITKNITSFHIDTPERISVEENSILHKPLGLDLELKNNFLPSGNINVGITSGASTPDKVVADVIEKLTVIAS
>Mature_398_residues
MDTQAFRRSLHHSDRYNRRGFDSPTKRAQALEEAYQSDLISSIRDNGFTYNKGRLNIKLAKAFGFCWGVERAVAMAYETR
RHYPNENIWITNEIIHNPSVNDHLRKMNVKFISAKNGIKDFSLVSNGDVVILPAFGATVQEMKLLHEKGCHIIDTTCPWV
SKVWHTVEKHKKHVFTSIIHGKFKHEETLATSSFAGKYLVVLDLEEANYISEYILGRGNRNEFMNKFAKACSDGFDPDKD
LDRVGVANQTTMLKSETEEIGKVFEKTMLKKFGPENLNSHFLAFNTICDATEERQDAMFSLVDEDLDILVVIGGFNSSNT
THLQEIAITKNITSFHIDTPERISVEENSILHKPLGLDLELKNNFLPSGNINVGITSGASTPDKVVADVIEKLTVIAS

Specific function: Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) [H]

COG id: COG0761

COG function: function code IM; Penicillin tolerance protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ispH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003451 [H]

Pfam domain/function: PF02401 LYTB [H]

EC number: =1.17.1.2 [H]

Molecular weight: Translated: 44869; Mature: 44869

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDTQAFRRSLHHSDRYNRRGFDSPTKRAQALEEAYQSDLISSIRDNGFTYNKGRLNIKLA
CCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEECCCEEEEEEH
KAFGFCWGVERAVAMAYETRRHYPNENIWITNEIIHNPSVNDHLRKMNVKFISAKNGIKD
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHEECCCCHHHHHHHHCEEEEECCCCCCC
FSLVSNGDVVILPAFGATVQEMKLLHEKGCHIIDTTCPWVSKVWHTVEKHKKHVFTSIIH
CEEECCCCEEEEECCCCHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
GKFKHEETLATSSFAGKYLVVLDLEEANYISEYILGRGNRNEFMNKFAKACSDGFDPDKD
CHHCCHHHHHHHHCCCCEEEEEEECHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCC
LDRVGVANQTTMLKSETEEIGKVFEKTMLKKFGPENLNSHFLAFNTICDATEERQDAMFS
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHCCHHHHHHHHHH
LVDEDLDILVVIGGFNSSNTTHLQEIAITKNITSFHIDTPERISVEENSILHKPLGLDLE
HHCCCCEEEEEEECCCCCCCCHHHHHHEECCCEEEECCCCCCCCCCCCCEEECCCCCEEE
LKNNFLPSGNINVGITSGASTPDKVVADVIEKLTVIAS
ECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDTQAFRRSLHHSDRYNRRGFDSPTKRAQALEEAYQSDLISSIRDNGFTYNKGRLNIKLA
CCHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEECCCEEEEEEH
KAFGFCWGVERAVAMAYETRRHYPNENIWITNEIIHNPSVNDHLRKMNVKFISAKNGIKD
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHEECCCCHHHHHHHHCEEEEECCCCCCC
FSLVSNGDVVILPAFGATVQEMKLLHEKGCHIIDTTCPWVSKVWHTVEKHKKHVFTSIIH
CEEECCCCEEEEECCCCHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
GKFKHEETLATSSFAGKYLVVLDLEEANYISEYILGRGNRNEFMNKFAKACSDGFDPDKD
CHHCCHHHHHHHHCCCCEEEEEEECHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCC
LDRVGVANQTTMLKSETEEIGKVFEKTMLKKFGPENLNSHFLAFNTICDATEERQDAMFS
HHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHCCHHHHHHHHHH
LVDEDLDILVVIGGFNSSNTTHLQEIAITKNITSFHIDTPERISVEENSILHKPLGLDLE
HHCCCCEEEEEEECCCCCCCCHHHHHHEECCCEEEECCCCCCCCCCCCCEEECCCCCEEE
LKNNFLPSGNINVGITSGASTPDKVVADVIEKLTVIAS
ECCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA