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The map label for this gene is ubiB [C]

Identifier: 78778597

GI number: 78778597

Start: 203316

End: 204983

Strand: Reverse

Name: ubiB [C]

Synonym: PMT9312_0211

Alternate gene names: 78778597

Gene position: 204983-203316 (Counterclockwise)

Preceding gene: 78778598

Following gene: 78778595

Centisome position: 11.99

GC content: 32.25

Gene sequence:

>1668_bases
ATGAGTTATCACATTCTTCATTATCGTTTAAAAAAATTGAAGAGAGGCTTTCTTATTTGGATAACCCTTATTTCGCTATT
AATAAATTTGTGGCTAGATAATATTAGATTTACAATTTTCCAAACTAAGAGCAATAAAAAAAGTAGGGTCCAAATTAAAC
GAGCTAAGTGTTTTACTAATCAATTAATTAAGCTTGGTTCAGCATTTATTAAAATTGGACAATTACTATCAGCGAGACCT
GATTTAATTCCTAATACCTGGATACAGGAATTAGCTAAATTACAGGATCAAGTTCCTAATTTTTCATTTGAACAAGTTGA
AGAAACTATCAGAGAAGAAATAGGATCAAAATTTAATGAAATAGATTTTATAATAACTGATCCTGTTGGATCAGCATCAC
TAGCTCAGGTTCATAGGGCGACTTTAAAAGATGGTAAGAATGTAGTATTTAAAGTTCAAAGACCCAATTTAAAAGAATTG
TTTGTTATCGATTTAGGTATAATGCAGCAAATAGCAGGATTATTGCAGAAAAATAAGAATTGGAGTCGAGGTAGAAACTG
GATTGAGATTGCTAAAGAGTGTAGGAAAGTTCTTATGAAGGAGCTTGATTTTAAGTGTGAAGCGCAATATGCAGCAAGAT
TTAGACAGCAATTTCTTGATGATGAAAATGTTGAAATTCCTGAAGTAATTTGGGATATGAGTAGCGAAAAAGTGCTTTGT
TTAAGTTATCTAGAGGGAACAAAAATAAGCGATTTAGAAAAATTAGAATCCCAAAAAATTGATTTGCCAAAAATTGCAGA
AATAGGTGCCATCAGCTACTTAAAACAATTAGTAAATTACGGTTTTTTTCATGCAGACCCTCATCCAGGGAATCTAGCAG
TTTCAAATACAGGTAAATTGATTTTTTATGATTTTGGCATGATGGGGAATATCTCCAATAACCTTCAAACAAGATTAGGG
GGGATGGTTAAGGCTGCAGCTTTAAGAGATGCCTCATCACTTGTAAGTCAATTACAACAAGCTGGTCTAATTTCAAAAGA
TATTGATATCGGGCCAGTAAGAAGATTAGTTAGATTAATGCTTAAAGAAGCCTTAACTCCTCCATTTAGTTCAAATATTA
TTGAAAAATTATCTGGAGATTTATACGAACTTGTTTATGAAACACCATTTCAACTGCCTGTGGATCTAATCTTTGTAATG
AGAGCTTTATCAACTTTTGAAGGAGTTGGTAGAATGCTTGACCCAGGGTTTAACCTTGTATCAGTTACCAAGCCTTATTT
AATAGAACTTATGACTTCTAATAATCAAACTCCTAACGATTTAATTAACCAATTTGGAAGGCAAGTAGGTGAACTAGGAT
CCAAAGCTGTAGGAATTCCCAAAAGAATAGATGAAAGTTTAGAAAGATTAGAGCAGGGAGATTTACAATTGCAAATAAGA
ATGGGGGAGTCTGATAGACAATTCAAAAAAATGTTTACCGCTCAAAAAACTTTAGGCCATTCAATTCTTATAGGAAGCTT
ATCAATTGCATCCGCTTTACTTGTAACTAATAAACAAAATAATTTTGCATTGTTACCATTATTTTTTGCAGTACCAATAA
GTATTGATTGGATAAAATGCCAATTAATTATGAGTAAAGGCTCACGTTTAGAAAAACTTAAGCGCTAG

Upstream 100 bases:

>100_bases
ATACTTATCAAAATTCGAAAATAAAAAAAGCTTTAAATGAAATAGAAGGTATCAATAAGCAAATTGATCTATTTAATAAA
ACAATAAATAATCAAATTTA

Downstream 100 bases:

>100_bases
AAAAACTATATATTTTTGGGTCCTAAACCTAAAGCTCCAGCGAATCTTGCTTGATTTCCCAACTCCTCCTCAATTTTTAA
AAGCCTATTATATTTAGCAA

Product: putative kinase

Products: 2-octaprenyl-6-hydroxyphenol [C]

Alternate protein names: NA

Number of amino acids: Translated: 555; Mature: 554

Protein sequence:

>555_residues
MSYHILHYRLKKLKRGFLIWITLISLLINLWLDNIRFTIFQTKSNKKSRVQIKRAKCFTNQLIKLGSAFIKIGQLLSARP
DLIPNTWIQELAKLQDQVPNFSFEQVEETIREEIGSKFNEIDFIITDPVGSASLAQVHRATLKDGKNVVFKVQRPNLKEL
FVIDLGIMQQIAGLLQKNKNWSRGRNWIEIAKECRKVLMKELDFKCEAQYAARFRQQFLDDENVEIPEVIWDMSSEKVLC
LSYLEGTKISDLEKLESQKIDLPKIAEIGAISYLKQLVNYGFFHADPHPGNLAVSNTGKLIFYDFGMMGNISNNLQTRLG
GMVKAAALRDASSLVSQLQQAGLISKDIDIGPVRRLVRLMLKEALTPPFSSNIIEKLSGDLYELVYETPFQLPVDLIFVM
RALSTFEGVGRMLDPGFNLVSVTKPYLIELMTSNNQTPNDLINQFGRQVGELGSKAVGIPKRIDESLERLEQGDLQLQIR
MGESDRQFKKMFTAQKTLGHSILIGSLSIASALLVTNKQNNFALLPLFFAVPISIDWIKCQLIMSKGSRLEKLKR

Sequences:

>Translated_555_residues
MSYHILHYRLKKLKRGFLIWITLISLLINLWLDNIRFTIFQTKSNKKSRVQIKRAKCFTNQLIKLGSAFIKIGQLLSARP
DLIPNTWIQELAKLQDQVPNFSFEQVEETIREEIGSKFNEIDFIITDPVGSASLAQVHRATLKDGKNVVFKVQRPNLKEL
FVIDLGIMQQIAGLLQKNKNWSRGRNWIEIAKECRKVLMKELDFKCEAQYAARFRQQFLDDENVEIPEVIWDMSSEKVLC
LSYLEGTKISDLEKLESQKIDLPKIAEIGAISYLKQLVNYGFFHADPHPGNLAVSNTGKLIFYDFGMMGNISNNLQTRLG
GMVKAAALRDASSLVSQLQQAGLISKDIDIGPVRRLVRLMLKEALTPPFSSNIIEKLSGDLYELVYETPFQLPVDLIFVM
RALSTFEGVGRMLDPGFNLVSVTKPYLIELMTSNNQTPNDLINQFGRQVGELGSKAVGIPKRIDESLERLEQGDLQLQIR
MGESDRQFKKMFTAQKTLGHSILIGSLSIASALLVTNKQNNFALLPLFFAVPISIDWIKCQLIMSKGSRLEKLKR
>Mature_554_residues
SYHILHYRLKKLKRGFLIWITLISLLINLWLDNIRFTIFQTKSNKKSRVQIKRAKCFTNQLIKLGSAFIKIGQLLSARPD
LIPNTWIQELAKLQDQVPNFSFEQVEETIREEIGSKFNEIDFIITDPVGSASLAQVHRATLKDGKNVVFKVQRPNLKELF
VIDLGIMQQIAGLLQKNKNWSRGRNWIEIAKECRKVLMKELDFKCEAQYAARFRQQFLDDENVEIPEVIWDMSSEKVLCL
SYLEGTKISDLEKLESQKIDLPKIAEIGAISYLKQLVNYGFFHADPHPGNLAVSNTGKLIFYDFGMMGNISNNLQTRLGG
MVKAAALRDASSLVSQLQQAGLISKDIDIGPVRRLVRLMLKEALTPPFSSNIIEKLSGDLYELVYETPFQLPVDLIFVMR
ALSTFEGVGRMLDPGFNLVSVTKPYLIELMTSNNQTPNDLINQFGRQVGELGSKAVGIPKRIDESLERLEQGDLQLQIRM
GESDRQFKKMFTAQKTLGHSILIGSLSIASALLVTNKQNNFALLPLFFAVPISIDWIKCQLIMSKGSRLEKLKR

Specific function: Required, Probably Indirectly, For The Hydroxylation Of 2-Octaprenylphenol To 2-Octaprenyl-6-Hydroxy-Phenol, The Fourth Step In Ubiquinone Biosynthesis. Specific For Aerobically Grown Log-Phase Cells. [C]

COG id: COG0661

COG function: function code R; Predicted unusual protein kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protein kinase superfamily. ADCK protein kinase family [H]

Homologues:

Organism=Homo sapiens, GI40254938, Length=267, Percent_Identity=31.4606741573034, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI41393593, Length=375, Percent_Identity=27.7333333333333, Blast_Score=135, Evalue=1e-31,
Organism=Homo sapiens, GI217035081, Length=215, Percent_Identity=32.5581395348837, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI34147522, Length=276, Percent_Identity=24.2753623188406, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI27363457, Length=272, Percent_Identity=23.8970588235294, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI2367309, Length=522, Percent_Identity=27.2030651340996, Blast_Score=164, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17559152, Length=257, Percent_Identity=30.7392996108949, Blast_Score=122, Evalue=5e-28,
Organism=Caenorhabditis elegans, GI32565180, Length=291, Percent_Identity=24.7422680412371, Blast_Score=86, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6323282, Length=281, Percent_Identity=30.6049822064057, Blast_Score=112, Evalue=2e-25,
Organism=Saccharomyces cerevisiae, GI6321319, Length=293, Percent_Identity=26.6211604095563, Blast_Score=97, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6325148, Length=432, Percent_Identity=22.2222222222222, Blast_Score=84, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24662575, Length=397, Percent_Identity=27.455919395466, Blast_Score=142, Evalue=6e-34,
Organism=Drosophila melanogaster, GI22024280, Length=309, Percent_Identity=29.4498381877023, Blast_Score=137, Evalue=1e-32,
Organism=Drosophila melanogaster, GI18859849, Length=261, Percent_Identity=24.904214559387, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004147
- InterPro:   IPR011009
- InterPro:   IPR000719 [H]

Pfam domain/function: PF03109 ABC1 [H]

EC number: NA

Molecular weight: Translated: 63056; Mature: 62924

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: PS50011 PROTEIN_KINASE_DOM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYHILHYRLKKLKRGFLIWITLISLLINLWLDNIRFTIFQTKSNKKSRVQIKRAKCFTN
CCEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHH
QLIKLGSAFIKIGQLLSARPDLIPNTWIQELAKLQDQVPNFSFEQVEETIREEIGSKFNE
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCC
IDFIITDPVGSASLAQVHRATLKDGKNVVFKVQRPNLKELFVIDLGIMQQIAGLLQKNKN
CCEEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCC
WSRGRNWIEIAKECRKVLMKELDFKCEAQYAARFRQQFLDDENVEIPEVIWDMSSEKVLC
HHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCEEE
LSYLEGTKISDLEKLESQKIDLPKIAEIGAISYLKQLVNYGFFHADPHPGNLAVSNTGKL
EEHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEECCCCCCCEEEECCCCE
IFYDFGMMGNISNNLQTRLGGMVKAAALRDASSLVSQLQQAGLISKDIDIGPVRRLVRLM
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
LKEALTPPFSSNIIEKLSGDLYELVYETPFQLPVDLIFVMRALSTFEGVGRMLDPGFNLV
HHHHCCCCCCHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEE
SVTKPYLIELMTSNNQTPNDLINQFGRQVGELGSKAVGIPKRIDESLERLEQGDLQLQIR
EECCHHHHEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEE
MGESDRQFKKMFTAQKTLGHSILIGSLSIASALLVTNKQNNFALLPLFFAVPISIDWIKC
ECCCHHHHHHHHHHHHHHCCHHEEEHHHHHHHHHEECCCCCEEEEHHHHHHCCEEEHHHH
QLIMSKGSRLEKLKR
HHHHHCCHHHHHHCC
>Mature Secondary Structure 
SYHILHYRLKKLKRGFLIWITLISLLINLWLDNIRFTIFQTKSNKKSRVQIKRAKCFTN
CEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHHHH
QLIKLGSAFIKIGQLLSARPDLIPNTWIQELAKLQDQVPNFSFEQVEETIREEIGSKFNE
HHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCC
IDFIITDPVGSASLAQVHRATLKDGKNVVFKVQRPNLKELFVIDLGIMQQIAGLLQKNKN
CCEEEECCCCCHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCC
WSRGRNWIEIAKECRKVLMKELDFKCEAQYAARFRQQFLDDENVEIPEVIWDMSSEKVLC
HHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCEEE
LSYLEGTKISDLEKLESQKIDLPKIAEIGAISYLKQLVNYGFFHADPHPGNLAVSNTGKL
EEHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEECCCCCCCEEEECCCCE
IFYDFGMMGNISNNLQTRLGGMVKAAALRDASSLVSQLQQAGLISKDIDIGPVRRLVRLM
EEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
LKEALTPPFSSNIIEKLSGDLYELVYETPFQLPVDLIFVMRALSTFEGVGRMLDPGFNLV
HHHHCCCCCCHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEE
SVTKPYLIELMTSNNQTPNDLINQFGRQVGELGSKAVGIPKRIDESLERLEQGDLQLQIR
EECCHHHHEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEE
MGESDRQFKKMFTAQKTLGHSILIGSLSIASALLVTNKQNNFALLPLFFAVPISIDWIKC
ECCCHHHHHHHHHHHHHHCCHHEEEHHHHHHHHHEECCCCCEEEEHHHHHHCCEEEHHHH
QLIMSKGSRLEKLKR
HHHHHCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2 2-octaprenylphenol; O2 [C]

Specific reaction: 2 2-octaprenylphenol + O2 = 2 2-octaprenyl-6-hydroxyphenol [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]