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The map label for this gene is fabD [H]

Identifier: 78778525

GI number: 78778525

Start: 135900

End: 136796

Strand: Direct

Name: fabD [H]

Synonym: PMT9312_0139

Alternate gene names: 78778525

Gene position: 135900-136796 (Clockwise)

Preceding gene: 78778524

Following gene: 78778526

Centisome position: 7.95

GC content: 31.55

Gene sequence:

>897_bases
ATGACAGTTGCATGGGTATTCCCTGGACAAGGTTCGCAAAAAATTGGGATGGCAAAACAAATTGAAAATTTGCCTAACAC
AAAGGAGAGGTTTAGATTCGCGTCTGAGATATTTGATAGAAATTTATTTGAAATTTGTGAGTTGAATTCTGAACCAATTA
ATTCCCTTAATGATTTAAATAACACAATAAATACACAAATTTGTCTTTTTTTAGTTGAATCGATTTTATTAGATGCACTA
AAGGAAAATGGTTATAAACCAAATTATGTTGCTGGGCATAGTCTAGGAGAAATCACGGCACTCTATTGTGCAGATGTTTT
TTCATTCGAAGATTGTGTATCACTAATAAAAGTAAGATCTCAATTAATGGTTAATACTGGGAAAGGATCTATGGCAGCAT
TAATTGGTTTTGATAGAGATCAACTTGATTTATTAGTAAATCAAATTGATGATGTTGTAATAGCTAATGATAATAGTTCC
TCCCAAGTTGTCTTATCAGGATCTTATGAAGCATTAGATTATTTGTCTAAAGAAATTTCTTGTAAACGATTCCTCAAATT
AAATGTTTCAGGTGCATTTCACTCACCATTCATGAATGATCCTTCAGCAAAATTTGCTGAGTATTTAAAAAAGATTGAAT
TTAAAAATCCTTCTTTTCCAGTCATAAGTAACTATAAACCTTCATTTTGTAGCGATCCAAACGAGCTTAAAATAAGATTG
GAAAATCAAATGTGTAATGGGGTAAGGTGGCGAGAAACTATGGATTTAATGGCGAAAGATAGTGATCTTCATATTGTTGA
AATTGGCCCCTCCAATGTACTTAGCGGTTTAGGAAAAAGACATTTGAAGGGTGTAAAAATTTCTCAAATTTCATCTTCTG
ATCAAATAACATATTAA

Upstream 100 bases:

>100_bases
AATTAAACAAAATGATATTATTGCCACAAGTGGTTTTGGTGCTGGGCTAAGTTGGGGTGCAGCCCTCATTAAATGGGGTT
AAAACAAAATTAGGAAAATT

Downstream 100 bases:

>100_bases
TTCCTATGAAAAATGATTTTTTTCAAAAATTAACCTATCAATTAGTTAGTAATTTATTTGTGTTACCTATTTATAAATTT
GTATTTCGCGGTCATTTAAT

Product: malonyl CoA-acyl carrier protein transacylase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MTVAWVFPGQGSQKIGMAKQIENLPNTKERFRFASEIFDRNLFEICELNSEPINSLNDLNNTINTQICLFLVESILLDAL
KENGYKPNYVAGHSLGEITALYCADVFSFEDCVSLIKVRSQLMVNTGKGSMAALIGFDRDQLDLLVNQIDDVVIANDNSS
SQVVLSGSYEALDYLSKEISCKRFLKLNVSGAFHSPFMNDPSAKFAEYLKKIEFKNPSFPVISNYKPSFCSDPNELKIRL
ENQMCNGVRWRETMDLMAKDSDLHIVEIGPSNVLSGLGKRHLKGVKISQISSSDQITY

Sequences:

>Translated_298_residues
MTVAWVFPGQGSQKIGMAKQIENLPNTKERFRFASEIFDRNLFEICELNSEPINSLNDLNNTINTQICLFLVESILLDAL
KENGYKPNYVAGHSLGEITALYCADVFSFEDCVSLIKVRSQLMVNTGKGSMAALIGFDRDQLDLLVNQIDDVVIANDNSS
SQVVLSGSYEALDYLSKEISCKRFLKLNVSGAFHSPFMNDPSAKFAEYLKKIEFKNPSFPVISNYKPSFCSDPNELKIRL
ENQMCNGVRWRETMDLMAKDSDLHIVEIGPSNVLSGLGKRHLKGVKISQISSSDQITY
>Mature_297_residues
TVAWVFPGQGSQKIGMAKQIENLPNTKERFRFASEIFDRNLFEICELNSEPINSLNDLNNTINTQICLFLVESILLDALK
ENGYKPNYVAGHSLGEITALYCADVFSFEDCVSLIKVRSQLMVNTGKGSMAALIGFDRDQLDLLVNQIDDVVIANDNSSS
QVVLSGSYEALDYLSKEISCKRFLKLNVSGAFHSPFMNDPSAKFAEYLKKIEFKNPSFPVISNYKPSFCSDPNELKIRLE
NQMCNGVRWRETMDLMAKDSDLHIVEIGPSNVLSGLGKRHLKGVKISQISSSDQITY

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=301, Percent_Identity=24.2524916943522, Blast_Score=95, Evalue=9e-20,
Organism=Escherichia coli, GI1787334, Length=288, Percent_Identity=34.0277777777778, Blast_Score=148, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI71984332, Length=271, Percent_Identity=24.3542435424354, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24665753, Length=279, Percent_Identity=30.4659498207885, Blast_Score=117, Evalue=7e-27,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 33362; Mature: 33231

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVAWVFPGQGSQKIGMAKQIENLPNTKERFRFASEIFDRNLFEICELNSEPINSLNDLN
CEEEEEECCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHHCCCCCHHHHHHHH
NTINTQICLFLVESILLDALKENGYKPNYVAGHSLGEITALYCADVFSFEDCVSLIKVRS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHH
QLMVNTGKGSMAALIGFDRDQLDLLVNQIDDVVIANDNSSSQVVLSGSYEALDYLSKEIS
HHEEECCCCCEEEEEECCHHHHHHHHHHHCCEEEECCCCCCEEEEECCHHHHHHHHHHHC
CKRFLKLNVSGAFHSPFMNDPSAKFAEYLKKIEFKNPSFPVISNYKPSFCSDPNELKIRL
HHHEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCCCEEEEE
ENQMCNGVRWRETMDLMAKDSDLHIVEIGPSNVLSGLGKRHLKGVKISQISSSDQITY
CCHHHCCCHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHCCCEEEECCCCCCCCC
>Mature Secondary Structure 
TVAWVFPGQGSQKIGMAKQIENLPNTKERFRFASEIFDRNLFEICELNSEPINSLNDLN
EEEEEECCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHHCCCCCHHHHHHHH
NTINTQICLFLVESILLDALKENGYKPNYVAGHSLGEITALYCADVFSFEDCVSLIKVRS
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHH
QLMVNTGKGSMAALIGFDRDQLDLLVNQIDDVVIANDNSSSQVVLSGSYEALDYLSKEIS
HHEEECCCCCEEEEEECCHHHHHHHHHHHCCEEEECCCCCCEEEEECCHHHHHHHHHHHC
CKRFLKLNVSGAFHSPFMNDPSAKFAEYLKKIEFKNPSFPVISNYKPSFCSDPNELKIRL
HHHEEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCCCCEEEEE
ENQMCNGVRWRETMDLMAKDSDLHIVEIGPSNVLSGLGKRHLKGVKISQISSSDQITY
CCHHHCCCHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHCCCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]