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The map label for this gene is fabH [H]

Identifier: 78778524

GI number: 78778524

Start: 134874

End: 135881

Strand: Direct

Name: fabH [H]

Synonym: PMT9312_0138

Alternate gene names: 78778524

Gene position: 134874-135881 (Clockwise)

Preceding gene: 78778523

Following gene: 78778525

Centisome position: 7.89

GC content: 34.72

Gene sequence:

>1008_bases
TTGGAAGGAATAAAGTTTAATCAGATTGGAGTCTCATTTAAAGGTAGTGGAAGTTATGTACCCGATCAAATACTAACCAA
TGAAACAATTAGTCAAAAAGTAGATACTAGTGATGAATGGATAAAATCTAGAACTGGCATTTCTGAGAGGAGAATTTCTG
GCTTAGGAGATAATGTCAATGATATGGCTTATGAGGCGGCACTATCAGCGATTGAAATGACTAATTGGGATATTAAAACG
ATTGATTTAATTGTCTTAGCTACTTCTACACCTCATGATTTATTTGGTTCAGCGCCATCTATACAAGCTAAATTGGGTGC
CCATAATGCTGTAGCTTTCGATTTAACTGCAGCATGTAGTGGTTTTTTATTCGCCTTAATAACAGCCTCACAATTTTTAA
AAGGAGGTAGTTTTAAGAGAGCTATTGTTATAGGAGCGGATCAATTATCAAGCTTTGTTGATTGGAATGATAGAAGAAGT
TGTATTCTATTTGGAGACGGTGCGGGTGCATTGGCAATTGAAGCCACAAATGAATTTGATAATTTCCTTGGTTTTGATAT
GAGAACAGATGGGGAAAGAGGTTCTTTCCTAAATCTTCCATCAAAAAATAATAAGGATTTAATAATTGATAACATTGATT
TTTTAAATGGGGGTTTTTCTCCAATTCAGATGAATGGTCAGGAAGTCTATAAATTTGCGGTTAGAGAAGTTCCGATAATT
CTTGATAATTTGTTTAGAAAAACGAATTATACTTCTGACGAAGTTGATTGGCTCATACTGCATCAAGCTAATCAAAGAAT
ATTGGATTCTGTAGGAGACAGATTAAAAATTCCTAGAGAAAAAATTCTTAGCAATTTAGCAAAATATGGCAATACCTCAG
CAGCAACAATTCCACTAGTGATGGATGAGGCTATTAGAAATAATAGAATTAAACAAAATGATATTATTGCCACAAGTGGT
TTTGGTGCTGGGCTAAGTTGGGGTGCAGCCCTCATTAAATGGGGTTAA

Upstream 100 bases:

>100_bases
GAAAATTTAAATCAACTTCAAAAGCTTCAAGTTTTAAATTCATAAAACATATTTTGTCAAATTTTATGTTTGACTTATAT
AAGTAACTAAAAAAACTCTT

Downstream 100 bases:

>100_bases
AACAAAATTAGGAAAATTATGACAGTTGCATGGGTATTCCCTGGACAAGGTTCGCAAAAAATTGGGATGGCAAAACAAAT
TGAAAATTTGCCTAACACAA

Product: 3-oxoacyl-(acyl carrier protein) synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MEGIKFNQIGVSFKGSGSYVPDQILTNETISQKVDTSDEWIKSRTGISERRISGLGDNVNDMAYEAALSAIEMTNWDIKT
IDLIVLATSTPHDLFGSAPSIQAKLGAHNAVAFDLTAACSGFLFALITASQFLKGGSFKRAIVIGADQLSSFVDWNDRRS
CILFGDGAGALAIEATNEFDNFLGFDMRTDGERGSFLNLPSKNNKDLIIDNIDFLNGGFSPIQMNGQEVYKFAVREVPII
LDNLFRKTNYTSDEVDWLILHQANQRILDSVGDRLKIPREKILSNLAKYGNTSAATIPLVMDEAIRNNRIKQNDIIATSG
FGAGLSWGAALIKWG

Sequences:

>Translated_335_residues
MEGIKFNQIGVSFKGSGSYVPDQILTNETISQKVDTSDEWIKSRTGISERRISGLGDNVNDMAYEAALSAIEMTNWDIKT
IDLIVLATSTPHDLFGSAPSIQAKLGAHNAVAFDLTAACSGFLFALITASQFLKGGSFKRAIVIGADQLSSFVDWNDRRS
CILFGDGAGALAIEATNEFDNFLGFDMRTDGERGSFLNLPSKNNKDLIIDNIDFLNGGFSPIQMNGQEVYKFAVREVPII
LDNLFRKTNYTSDEVDWLILHQANQRILDSVGDRLKIPREKILSNLAKYGNTSAATIPLVMDEAIRNNRIKQNDIIATSG
FGAGLSWGAALIKWG
>Mature_335_residues
MEGIKFNQIGVSFKGSGSYVPDQILTNETISQKVDTSDEWIKSRTGISERRISGLGDNVNDMAYEAALSAIEMTNWDIKT
IDLIVLATSTPHDLFGSAPSIQAKLGAHNAVAFDLTAACSGFLFALITASQFLKGGSFKRAIVIGADQLSSFVDWNDRRS
CILFGDGAGALAIEATNEFDNFLGFDMRTDGERGSFLNLPSKNNKDLIIDNIDFLNGGFSPIQMNGQEVYKFAVREVPII
LDNLFRKTNYTSDEVDWLILHQANQRILDSVGDRLKIPREKILSNLAKYGNTSAATIPLVMDEAIRNNRIKQNDIIATSG
FGAGLSWGAALIKWG

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=322, Percent_Identity=40.9937888198758, Blast_Score=250, Evalue=8e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.41 [H]

Molecular weight: Translated: 36659; Mature: 36659

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGIKFNQIGVSFKGSGSYVPDQILTNETISQKVDTSDEWIKSRTGISERRISGLGDNVN
CCCCEEEEEEEEECCCCCCCCHHHHCCCHHHHHCCCCHHHHHHHCCCCHHHHHCCCCCHH
DMAYEAALSAIEMTNWDIKTIDLIVLATSTPHDLFGSAPSIQAKLGAHNAVAFDLTAACS
HHHHHHHHHHHHCCCCCEEEEEEEEEECCCCHHHHCCCCCCEEECCCCCEEEEEHHHHHH
GFLFALITASQFLKGGSFKRAIVIGADQLSSFVDWNDRRSCILFGDGAGALAIEATNEFD
HHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCHHH
NFLGFDMRTDGERGSFLNLPSKNNKDLIIDNIDFLNGGFSPIQMNGQEVYKFAVREVPII
HHHCCCCCCCCCCCCEEECCCCCCCEEEEECCHHCCCCCCEEEECHHHHHHHHHHHHHHH
LDNLFRKTNYTSDEVDWLILHQANQRILDSVGDRLKIPREKILSNLAKYGNTSAATIPLV
HHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEHHH
MDEAIRNNRIKQNDIIATSGFGAGLSWGAALIKWG
HHHHHHCCCCCCCCEEEECCCCCCHHHCCEEEECC
>Mature Secondary Structure
MEGIKFNQIGVSFKGSGSYVPDQILTNETISQKVDTSDEWIKSRTGISERRISGLGDNVN
CCCCEEEEEEEEECCCCCCCCHHHHCCCHHHHHCCCCHHHHHHHCCCCHHHHHCCCCCHH
DMAYEAALSAIEMTNWDIKTIDLIVLATSTPHDLFGSAPSIQAKLGAHNAVAFDLTAACS
HHHHHHHHHHHHCCCCCEEEEEEEEEECCCCHHHHCCCCCCEEECCCCCEEEEEHHHHHH
GFLFALITASQFLKGGSFKRAIVIGADQLSSFVDWNDRRSCILFGDGAGALAIEATNEFD
HHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHCCCCCCEEEEEECCCCEEEEEECCHHH
NFLGFDMRTDGERGSFLNLPSKNNKDLIIDNIDFLNGGFSPIQMNGQEVYKFAVREVPII
HHHCCCCCCCCCCCCEEECCCCCCCEEEEECCHHCCCCCCEEEECHHHHHHHHHHHHHHH
LDNLFRKTNYTSDEVDWLILHQANQRILDSVGDRLKIPREKILSNLAKYGNTSAATIPLV
HHHHHHHCCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEHHH
MDEAIRNNRIKQNDIIATSGFGAGLSWGAALIKWG
HHHHHHCCCCCCCCEEEECCCCCCHHHCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA