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The map label for this gene is pgm [H]

Identifier: 78778464

GI number: 78778464

Start: 82855

End: 84492

Strand: Direct

Name: pgm [H]

Synonym: PMT9312_0079

Alternate gene names: 78778464

Gene position: 82855-84492 (Clockwise)

Preceding gene: 78778463

Following gene: 78778465

Centisome position: 4.85

GC content: 32.84

Gene sequence:

>1638_bases
ATGACTGAAGTTAGTGTAATAAATATCAATTCTCCCTTCTTAGATCAAAAACCCGGCACCTCTGGTTTAAGAAAAAGCAC
TTTAAAGTTTCAGCAAAAAAATTATCTAGAAATTTTTATAGAAGCAATTTTACAATCACTGGAAGATTTACAAGTTTCAA
CATTAGTAGTTGGTGGTGATGGCAGATATGGAAATATTGAAGCAATAGAAAAAATTGTGCAAATATGTGTTGCTCATAAA
GTGCAAAAGGTTATTGTTCCAAAATGTGGTTTATTATCTACTCCTGCTACATCACATTTAATTAGAAAAGAGAATGCTAT
TGGTGGCATTATTCTTTCTGCAAGTCATAATCCTGGAGGGATTGATGGTGACTTTGGAGTCAAGTTGAATATATCTAATG
GTGGCCCAGCTCCTGAGATGATTACTAATAAGATATTCAAAGCTTCACAATTACTTACTAGTTATAAAATTTGTAAAATT
CAACTACCAAATTTTACTGAATATGGAGCATATTCTTTCGGGGAAACTACCTTAGAAATTATTGATGGATTGAAAGATTA
TTCTGATTTGATGGAGGAAATTTTTGATTTTGATCAAATTAGTGATTTTTTAAAAAAAGACTTCTCATTAATTTTCGATG
CAATGAATGCGGTTACAGGCCCATATGCAACAAATATTTTTGTTGAAAAAATGGGTCTCTCAAATGATTGTGTTATGAAT
GGTACTCCGTTAAAAGATTTTGGCGGTTTACATCCTGATCCCAATCTTACTTATGCTTCTCATTTAGCTGATTTATTATT
AAATAAAAAATCTTATAGTTTTGGTGCTGCTTGCGATGGAGATGGCGATAGGAATATGATTCTGGGAAGTGGATGTTTTG
TAAATCCTAGTGATAGCCTGGCAGTGATTACTGCTAACACCAAATGTGTCCCTGGTTATAAAGATGGTATTACAGGTGTA
GCACGATCTATGCCAACTAGTTCAGCAGTTGATAACGTTGCGCGTGCATTAAATATCCCTTGTTTCGAGACACCTACTGG
GTGGAAATTTTTTGGAAATCTTTTAGATTCTAATTTAATTACATTATGTGGAGAAGAAAGTTTTGGAACAGGTAGTAATC
ATGTAAGGGAGAAAGATGGATTATGGGCAGTTTTGTATTGGTTACAAGTTTTAGCCGAAAAAAATTGTTCTGTAAGTGAT
TTGATACAGAGTCATTGGAAACAATTTGGTAGGAATTATTATTCAAGACATGATTATGAGGCAATTCCCTCAAATATTGC
TAATCAAATCTTTGGTGATCTAACTTCTAGGCTCGAAAATTTAAAAGGAAGTAATTTTGCTGGTCATTTAGTTCAAGTTG
CAGATAACTTTTCATATTTAGATCCTGTGGATGATTCCATAAGTGAAAATCAAGGTTTAAGATTGATTCTTGATGATAAT
TCACGCATAATTGTACGTCTTTCTGGAACTGGAACTAAGGGTGCAACATTAAGACTCTACTTTGAGAAATTTTTCAATTC
TAAACAGAATCTTTCGTTAAATCCTCAAGTCGCTTTGAAACCCCTAATAGATAATTTAGATGATTTGTTAAATATTTCAA
AACTTACTCAAATGCAAACTCCTACGGTAATTACATAG

Upstream 100 bases:

>100_bases
TAAGCGCATTATTAATTTCTTCATTATGGTTTATCGCTATGTTAAGAACATCCGAAATGCCTCATTAATTTAGTTAGATT
TTTGGAAGTATCTTAAAATT

Downstream 100 bases:

>100_bases
ACTTTAAAGTAATATTTCTTGATTTAATTTATATGCATTCCGAAAATTTATTTACCAATTATTCTCAAATAGAAAGTAAT
GCTCCTTTGGCAGATAAGTT

Product: phosphoglucomutase

Products: NA

Alternate protein names: PGM; Glucose phosphomutase [H]

Number of amino acids: Translated: 545; Mature: 544

Protein sequence:

>545_residues
MTEVSVININSPFLDQKPGTSGLRKSTLKFQQKNYLEIFIEAILQSLEDLQVSTLVVGGDGRYGNIEAIEKIVQICVAHK
VQKVIVPKCGLLSTPATSHLIRKENAIGGIILSASHNPGGIDGDFGVKLNISNGGPAPEMITNKIFKASQLLTSYKICKI
QLPNFTEYGAYSFGETTLEIIDGLKDYSDLMEEIFDFDQISDFLKKDFSLIFDAMNAVTGPYATNIFVEKMGLSNDCVMN
GTPLKDFGGLHPDPNLTYASHLADLLLNKKSYSFGAACDGDGDRNMILGSGCFVNPSDSLAVITANTKCVPGYKDGITGV
ARSMPTSSAVDNVARALNIPCFETPTGWKFFGNLLDSNLITLCGEESFGTGSNHVREKDGLWAVLYWLQVLAEKNCSVSD
LIQSHWKQFGRNYYSRHDYEAIPSNIANQIFGDLTSRLENLKGSNFAGHLVQVADNFSYLDPVDDSISENQGLRLILDDN
SRIIVRLSGTGTKGATLRLYFEKFFNSKQNLSLNPQVALKPLIDNLDDLLNISKLTQMQTPTVIT

Sequences:

>Translated_545_residues
MTEVSVININSPFLDQKPGTSGLRKSTLKFQQKNYLEIFIEAILQSLEDLQVSTLVVGGDGRYGNIEAIEKIVQICVAHK
VQKVIVPKCGLLSTPATSHLIRKENAIGGIILSASHNPGGIDGDFGVKLNISNGGPAPEMITNKIFKASQLLTSYKICKI
QLPNFTEYGAYSFGETTLEIIDGLKDYSDLMEEIFDFDQISDFLKKDFSLIFDAMNAVTGPYATNIFVEKMGLSNDCVMN
GTPLKDFGGLHPDPNLTYASHLADLLLNKKSYSFGAACDGDGDRNMILGSGCFVNPSDSLAVITANTKCVPGYKDGITGV
ARSMPTSSAVDNVARALNIPCFETPTGWKFFGNLLDSNLITLCGEESFGTGSNHVREKDGLWAVLYWLQVLAEKNCSVSD
LIQSHWKQFGRNYYSRHDYEAIPSNIANQIFGDLTSRLENLKGSNFAGHLVQVADNFSYLDPVDDSISENQGLRLILDDN
SRIIVRLSGTGTKGATLRLYFEKFFNSKQNLSLNPQVALKPLIDNLDDLLNISKLTQMQTPTVIT
>Mature_544_residues
TEVSVININSPFLDQKPGTSGLRKSTLKFQQKNYLEIFIEAILQSLEDLQVSTLVVGGDGRYGNIEAIEKIVQICVAHKV
QKVIVPKCGLLSTPATSHLIRKENAIGGIILSASHNPGGIDGDFGVKLNISNGGPAPEMITNKIFKASQLLTSYKICKIQ
LPNFTEYGAYSFGETTLEIIDGLKDYSDLMEEIFDFDQISDFLKKDFSLIFDAMNAVTGPYATNIFVEKMGLSNDCVMNG
TPLKDFGGLHPDPNLTYASHLADLLLNKKSYSFGAACDGDGDRNMILGSGCFVNPSDSLAVITANTKCVPGYKDGITGVA
RSMPTSSAVDNVARALNIPCFETPTGWKFFGNLLDSNLITLCGEESFGTGSNHVREKDGLWAVLYWLQVLAEKNCSVSDL
IQSHWKQFGRNYYSRHDYEAIPSNIANQIFGDLTSRLENLKGSNFAGHLVQVADNFSYLDPVDDSISENQGLRLILDDNS
RIIVRLSGTGTKGATLRLYFEKFFNSKQNLSLNPQVALKPLIDNLDDLLNISKLTQMQTPTVIT

Specific function: This enzyme participates in both the breakdown and synthesis of glucose. Required for the synthesis of capsular polysaccharide and normal lipopolysaccharide [H]

COG id: COG0033

COG function: function code G; Phosphoglucomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI290463102, Length=556, Percent_Identity=50.8992805755396, Blast_Score=544, Evalue=1e-155,
Organism=Homo sapiens, GI21361621, Length=564, Percent_Identity=49.113475177305, Blast_Score=533, Evalue=1e-151,
Organism=Homo sapiens, GI133922562, Length=556, Percent_Identity=45.3237410071942, Blast_Score=481, Evalue=1e-136,
Organism=Homo sapiens, GI290463104, Length=368, Percent_Identity=50.5434782608696, Blast_Score=369, Evalue=1e-102,
Organism=Homo sapiens, GI239741729, Length=114, Percent_Identity=47.3684210526316, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI239743670, Length=114, Percent_Identity=45.6140350877193, Blast_Score=92, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17535441, Length=558, Percent_Identity=46.5949820788531, Blast_Score=498, Evalue=1e-141,
Organism=Saccharomyces cerevisiae, GI6323752, Length=561, Percent_Identity=46.7023172905526, Blast_Score=483, Evalue=1e-137,
Organism=Saccharomyces cerevisiae, GI6322722, Length=561, Percent_Identity=46.8805704099822, Blast_Score=476, Evalue=1e-135,
Organism=Drosophila melanogaster, GI17864244, Length=552, Percent_Identity=48.9130434782609, Blast_Score=521, Evalue=1e-148,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.2 [H]

Molecular weight: Translated: 59743; Mature: 59611

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEVSVININSPFLDQKPGTSGLRKSTLKFQQKNYLEIFIEAILQSLEDLQVSTLVVGGD
CCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECC
GRYGNIEAIEKIVQICVAHKVQKVIVPKCGLLSTPATSHLIRKENAIGGIILSASHNPGG
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCC
IDGDFGVKLNISNGGPAPEMITNKIFKASQLLTSYKICKIQLPNFTEYGAYSFGETTLEI
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCCCCCCHHHHH
IDGLKDYSDLMEEIFDFDQISDFLKKDFSLIFDAMNAVTGPYATNIFVEKMGLSNDCVMN
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCCCCCEEC
GTPLKDFGGLHPDPNLTYASHLADLLLNKKSYSFGAACDGDGDRNMILGSGCFVNPSDSL
CCCCHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCEECCCCCE
AVITANTKCVPGYKDGITGVARSMPTSSAVDNVARALNIPCFETPTGWKFFGNLLDSNLI
EEEEECCEECCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCEE
TLCGEESFGTGSNHVREKDGLWAVLYWLQVLAEKNCSVSDLIQSHWKQFGRNYYSRHDYE
EEECCCCCCCCCCCCHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCH
AIPSNIANQIFGDLTSRLENLKGSNFAGHLVQVADNFSYLDPVDDSISENQGLRLILDDN
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECC
SRIIVRLSGTGTKGATLRLYFEKFFNSKQNLSLNPQVALKPLIDNLDDLLNISKLTQMQT
CEEEEEEECCCCCCCEEEEEHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
PTVIT
CCCCC
>Mature Secondary Structure 
TEVSVININSPFLDQKPGTSGLRKSTLKFQQKNYLEIFIEAILQSLEDLQVSTLVVGGD
CCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECC
GRYGNIEAIEKIVQICVAHKVQKVIVPKCGLLSTPATSHLIRKENAIGGIILSASHNPGG
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCCCEEEEEECCCCCC
IDGDFGVKLNISNGGPAPEMITNKIFKASQLLTSYKICKIQLPNFTEYGAYSFGETTLEI
CCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHCEEEEECCCCCCCCCCCCCCHHHHH
IDGLKDYSDLMEEIFDFDQISDFLKKDFSLIFDAMNAVTGPYATNIFVEKMGLSNDCVMN
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCCCCCCEEC
GTPLKDFGGLHPDPNLTYASHLADLLLNKKSYSFGAACDGDGDRNMILGSGCFVNPSDSL
CCCCHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCEECCCCCE
AVITANTKCVPGYKDGITGVARSMPTSSAVDNVARALNIPCFETPTGWKFFGNLLDSNLI
EEEEECCEECCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCEE
TLCGEESFGTGSNHVREKDGLWAVLYWLQVLAEKNCSVSDLIQSHWKQFGRNYYSRHDYE
EEECCCCCCCCCCCCHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCH
AIPSNIANQIFGDLTSRLENLKGSNFAGHLVQVADNFSYLDPVDDSISENQGLRLILDDN
HHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECC
SRIIVRLSGTGTKGATLRLYFEKFFNSKQNLSLNPQVALKPLIDNLDDLLNISKLTQMQT
CEEEEEEECCCCCCCEEEEEHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
PTVIT
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7959036; 2307661 [H]