Click here to switch to the map view.

The map label for this gene is argJ

Identifier: 78778436

GI number: 78778436

Start: 54595

End: 55833

Strand: Direct

Name: argJ

Synonym: PMT9312_0051

Alternate gene names: 78778436

Gene position: 54595-55833 (Clockwise)

Preceding gene: 78778434

Following gene: 78778438

Centisome position: 3.19

GC content: 33.25

Gene sequence:

>1239_bases
TTGAGCCAGTCTGATTCCACTTGGTCGTTTGTTGATGAAGGTAATGTAACACCCAACGGGTTTCTTTTTGCTGGCATATC
GGCTGGATTAAAAGCTTCTAATAAAAAAGATTTAGCACTTATACTTGCTCCAGAAGGAAGTATTTTTAGTGGGATGTTTA
CCCAATCTATAGTTCGCGCTTCTTGTGTTGATATTTGTGAGGAAAGGATTAAAAAATCTTCAGGTTTTGTACGAGCGATA
CTAATTAATTCTGGTCAAGCAAATGCATGTACAGGAAATCTTGGAATTCAACATTTTCAAATTGCTACAGCAATGATTGC
TGAACTTTTAGCAATAAAAGAAGAAGAAGTTTTAATGTGCTCAACTGGTGTAATAGGTGTTCCTATACAAATAAACGATT
TAGTAAAAAATTTACCGTATTTAGTGAGTGATTTAAAAGTTAATAATTTTCAAAATGCAGCAGAAGCAATTTTAACTACT
GATTTGACTTTGAAAAAAGTTTTAATAGAGACTTTTATTCAAGATAGAAAAATAAAAATAGCAGGATTTGCAAAAGGGTC
AGGCATGATTTATCCCAATATGGCTACAATGCTTGCCTTCCTAACCTGTGATGTGGGTATTGAGAAAGAAGAATGGGACA
ATATGATTTCTATTGCTGTTAAAAAATCTTTTAACGCAATATCAGTTGATGGAGAGACAAGCACAAATGATTCTTTCGTT
GCAATAAATGCAGGAGATAAAATTGATAAAAGATTTTTTCCAATCATCCAAGAAGGAATTGACATTGTATGTCAAAACTT
AGCAAAAAATATTGCGAGGGATGGAGAGGGAGCAAATTGTTTATTAGAAGTTTTAGTTCAAGGAGCAAAAAATACTGATG
ATGCAATTATCTTGGCTAAATCCATTTGTAATTCTGCATTGGTAAAAACAGCGATACATGGCTGTGATCCTAATTGGGGA
AGAATCATTTCTGCTGCTGGTAATTCTGGGGTTAAATTCACTCTAAATGAGGTTGACTTATATATAGGTAATGATCAGAT
TTTGGACAAGGGAAAGTTAAATCAATATGACTCGCAAAAAGTTACAGACTATATTAGGTCTAAAATGAAAGGTACATATT
TAGTGGATGATATTGTACAAATTATGATCAATCTCAATTCTGGCGAATCGAAAGGCAAAGCTTGGGGATGCGATCTTTCT
AAAAAGTATGTTGAAATAAATAGCGAATATACTACTTGA

Upstream 100 bases:

>100_bases
TTTAATTTTTGAAGAACATCCATATTTTTAATAATAATCTAATTACCTGTTTCTTTAGTATTAAAGAGAAGTTAGTATGA
ATTAAAAATATTAAAAGAGA

Downstream 100 bases:

>100_bases
GTTTTAGTAAATCTATTGGTAGATATTCATTAACATAAAGGAACAATATTGTTAAAGTTCCAATTATAGAACCTATAAAA
CCTCCAAATAAATTAACGAA

Product: bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein

Products: NA

Alternate protein names: Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS [H]

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MSQSDSTWSFVDEGNVTPNGFLFAGISAGLKASNKKDLALILAPEGSIFSGMFTQSIVRASCVDICEERIKKSSGFVRAI
LINSGQANACTGNLGIQHFQIATAMIAELLAIKEEEVLMCSTGVIGVPIQINDLVKNLPYLVSDLKVNNFQNAAEAILTT
DLTLKKVLIETFIQDRKIKIAGFAKGSGMIYPNMATMLAFLTCDVGIEKEEWDNMISIAVKKSFNAISVDGETSTNDSFV
AINAGDKIDKRFFPIIQEGIDIVCQNLAKNIARDGEGANCLLEVLVQGAKNTDDAIILAKSICNSALVKTAIHGCDPNWG
RIISAAGNSGVKFTLNEVDLYIGNDQILDKGKLNQYDSQKVTDYIRSKMKGTYLVDDIVQIMINLNSGESKGKAWGCDLS
KKYVEINSEYTT

Sequences:

>Translated_412_residues
MSQSDSTWSFVDEGNVTPNGFLFAGISAGLKASNKKDLALILAPEGSIFSGMFTQSIVRASCVDICEERIKKSSGFVRAI
LINSGQANACTGNLGIQHFQIATAMIAELLAIKEEEVLMCSTGVIGVPIQINDLVKNLPYLVSDLKVNNFQNAAEAILTT
DLTLKKVLIETFIQDRKIKIAGFAKGSGMIYPNMATMLAFLTCDVGIEKEEWDNMISIAVKKSFNAISVDGETSTNDSFV
AINAGDKIDKRFFPIIQEGIDIVCQNLAKNIARDGEGANCLLEVLVQGAKNTDDAIILAKSICNSALVKTAIHGCDPNWG
RIISAAGNSGVKFTLNEVDLYIGNDQILDKGKLNQYDSQKVTDYIRSKMKGTYLVDDIVQIMINLNSGESKGKAWGCDLS
KKYVEINSEYTT
>Mature_411_residues
SQSDSTWSFVDEGNVTPNGFLFAGISAGLKASNKKDLALILAPEGSIFSGMFTQSIVRASCVDICEERIKKSSGFVRAIL
INSGQANACTGNLGIQHFQIATAMIAELLAIKEEEVLMCSTGVIGVPIQINDLVKNLPYLVSDLKVNNFQNAAEAILTTD
LTLKKVLIETFIQDRKIKIAGFAKGSGMIYPNMATMLAFLTCDVGIEKEEWDNMISIAVKKSFNAISVDGETSTNDSFVA
INAGDKIDKRFFPIIQEGIDIVCQNLAKNIARDGEGANCLLEVLVQGAKNTDDAIILAKSICNSALVKTAIHGCDPNWGR
IISAAGNSGVKFTLNEVDLYIGNDQILDKGKLNQYDSQKVTDYIRSKMKGTYLVDDIVQIMINLNSGESKGKAWGCDLSK
KYVEINSEYTT

Specific function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis:the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate [H]

COG id: COG1364

COG function: function code E; N-acetylglutamate synthase (N-acetylornithine aminotransferase)

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgJ family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6323707, Length=422, Percent_Identity=31.7535545023697, Blast_Score=187, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002813
- InterPro:   IPR016117 [H]

Pfam domain/function: PF01960 ArgJ [H]

EC number: =2.3.1.35; =2.3.1.1 [H]

Molecular weight: Translated: 44662; Mature: 44531

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSDSTWSFVDEGNVTPNGFLFAGISAGLKASNKKDLALILAPEGSIFSGMFTQSIVRA
CCCCCCCEEEEECCCCCCCCEEEEEHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHH
SCVDICEERIKKSSGFVRAILINSGQANACTGNLGIQHFQIATAMIAELLAIKEEEVLMC
HHHHHHHHHHHHCCCCEEEEEEECCCCCCEECCCCCHHHHHHHHHHHHHHHCCCCCEEEE
STGVIGVPIQINDLVKNLPYLVSDLKVNNFQNAAEAILTTDLTLKKVLIETFIQDRKIKI
ECCEEEEEEEHHHHHHHCHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEE
AGFAKGSGMIYPNMATMLAFLTCDVGIEKEEWDNMISIAVKKSFNAISVDGETSTNDSFV
EEEECCCCEECCCHHHHHHHHHHCCCCCHHHHHCEEEEEEECCCCEEEECCCCCCCCCEE
AINAGDKIDKRFFPIIQEGIDIVCQNLAKNIARDGEGANCLLEVLVQGAKNTDDAIILAK
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCEEEHH
SICNSALVKTAIHGCDPNWGRIISAAGNSGVKFTLNEVDLYIGNDQILDKGKLNQYDSQK
HHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEEEEEEEEEECCCCEECCCCCCCCCHHH
VTDYIRSKMKGTYLVDDIVQIMINLNSGESKGKAWGCDLSKKYVEINSEYTT
HHHHHHHHCCCCCHHHHHHHHEEECCCCCCCCCEECCCCCCEEEEECCCCCC
>Mature Secondary Structure 
SQSDSTWSFVDEGNVTPNGFLFAGISAGLKASNKKDLALILAPEGSIFSGMFTQSIVRA
CCCCCCEEEEECCCCCCCCEEEEEHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHHH
SCVDICEERIKKSSGFVRAILINSGQANACTGNLGIQHFQIATAMIAELLAIKEEEVLMC
HHHHHHHHHHHHCCCCEEEEEEECCCCCCEECCCCCHHHHHHHHHHHHHHHCCCCCEEEE
STGVIGVPIQINDLVKNLPYLVSDLKVNNFQNAAEAILTTDLTLKKVLIETFIQDRKIKI
ECCEEEEEEEHHHHHHHCHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEE
AGFAKGSGMIYPNMATMLAFLTCDVGIEKEEWDNMISIAVKKSFNAISVDGETSTNDSFV
EEEECCCCEECCCHHHHHHHHHHCCCCCHHHHHCEEEEEEECCCCEEEECCCCCCCCCEE
AINAGDKIDKRFFPIIQEGIDIVCQNLAKNIARDGEGANCLLEVLVQGAKNTDDAIILAK
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCEEEHH
SICNSALVKTAIHGCDPNWGRIISAAGNSGVKFTLNEVDLYIGNDQILDKGKLNQYDSQK
HHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEEEEEEEEEECCCCEECCCCCCCCCHHH
VTDYIRSKMKGTYLVDDIVQIMINLNSGESKGKAWGCDLSKKYVEINSEYTT
HHHHHHHHCCCCCHHHHHHHHEEECCCCCCCCCEECCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]