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The map label for this gene is murB

Identifier: 78778406

GI number: 78778406

Start: 21682

End: 22575

Strand: Reverse

Name: murB

Synonym: PMT9312_0021

Alternate gene names: 78778406

Gene position: 22575-21682 (Counterclockwise)

Preceding gene: 78778407

Following gene: 78778405

Centisome position: 1.32

GC content: 28.97

Gene sequence:

>894_bases
ATGAATAAGAAAATTTTGTCTGAGAACTGTAATTTAAGTAATTATACAACTATAAAAGTTGGTGGAGTCGCAGAATATTT
TGCTGAACCAAGAAGTATTGAAGAATTTTCTTATCTAATAAAATGGTCTACATTAAATAATCACAAATGCCAAATAATTG
GCGCAGGTTCAAATCTTTTAATAAATAATATTTTCATAAAAGGTTTAGTTATATGTACAAAAAAAATGAAGTCATTAAGG
ATTGAGCCATATTCAGGAATTGTTGAGGCAGAAGCAGGTGTAATGCTCCCGACATTATCTAATTCTCTCGCTAAAAATGG
ATTACAAGGAGGAGAATGGGCTATCGGAATTCCAGGCACTTTAGGAGGAGCAATTTACATGAATGCTGGTACAGGTGATT
TATCCTTAGCAAAAAATCTTATTTCTGTGAAAGTTATTAATAATAAAACTCTTGAAACACTTGAAATTGAAAAAAAAGAT
ATCAATTTTGAGTATAGATTCAGCTCTTTTCAAAGTAATAATTTGGCAATTATTAGTTCAAAACTACATTTTGAACCTAA
TGGAAATCTCGCAAAATTAATTCAAAAAACGAAAAACAACCTTAAATTAAAAACAGCAGCACAGCCATATCATCTTCCAA
GTTTTGGTAGTGTTTTTAAAAATCCTGAAAATAGTTATGCAGCAAAATTAATTGATGATATGGGTTTAAAGGGATTTAAA
ATTGGCGGTGCTGAAATTTCTACAATGCATTCAAATTTTATAATTAACAATTCTTCGGCAAGTTCAAAAGATATTTATGA
ATTAATAACAGTAATTCAACAAAAAGTACTACAAAACAAAGGAATTTATTTGCAACCAGAAGTAAGAATGATTGGTTTTG
ACTATCCTAATTAA

Upstream 100 bases:

>100_bases
ACGAATTAACTCAAAAAGGGGATTTGATTTTGAATATGGGAGCTGGAGATTGTCATAATTTCTGGTCAATTTTAAATGGT
AAAAATAATTAAATTGATTT

Downstream 100 bases:

>100_bases
AGAAACTTTTTTAAAAAATGGCGGGTTTTGGACTTCCTAACTTTGGACAACTTACAGAAGCTTTTAAAAAAGCTAAACAA
ATTCAACAAGATGCTCAAAA

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MNKKILSENCNLSNYTTIKVGGVAEYFAEPRSIEEFSYLIKWSTLNNHKCQIIGAGSNLLINNIFIKGLVICTKKMKSLR
IEPYSGIVEAEAGVMLPTLSNSLAKNGLQGGEWAIGIPGTLGGAIYMNAGTGDLSLAKNLISVKVINNKTLETLEIEKKD
INFEYRFSSFQSNNLAIISSKLHFEPNGNLAKLIQKTKNNLKLKTAAQPYHLPSFGSVFKNPENSYAAKLIDDMGLKGFK
IGGAEISTMHSNFIINNSSASSKDIYELITVIQQKVLQNKGIYLQPEVRMIGFDYPN

Sequences:

>Translated_297_residues
MNKKILSENCNLSNYTTIKVGGVAEYFAEPRSIEEFSYLIKWSTLNNHKCQIIGAGSNLLINNIFIKGLVICTKKMKSLR
IEPYSGIVEAEAGVMLPTLSNSLAKNGLQGGEWAIGIPGTLGGAIYMNAGTGDLSLAKNLISVKVINNKTLETLEIEKKD
INFEYRFSSFQSNNLAIISSKLHFEPNGNLAKLIQKTKNNLKLKTAAQPYHLPSFGSVFKNPENSYAAKLIDDMGLKGFK
IGGAEISTMHSNFIINNSSASSKDIYELITVIQQKVLQNKGIYLQPEVRMIGFDYPN
>Mature_297_residues
MNKKILSENCNLSNYTTIKVGGVAEYFAEPRSIEEFSYLIKWSTLNNHKCQIIGAGSNLLINNIFIKGLVICTKKMKSLR
IEPYSGIVEAEAGVMLPTLSNSLAKNGLQGGEWAIGIPGTLGGAIYMNAGTGDLSLAKNLISVKVINNKTLETLEIEKKD
INFEYRFSSFQSNNLAIISSKLHFEPNGNLAKLIQKTKNNLKLKTAAQPYHLPSFGSVFKNPENSYAAKLIDDMGLKGFK
IGGAEISTMHSNFIINNSSASSKDIYELITVIQQKVLQNKGIYLQPEVRMIGFDYPN

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 32723; Mature: 32723

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKKILSENCNLSNYTTIKVGGVAEYFAEPRSIEEFSYLIKWSTLNNHKCQIIGAGSNLL
CCCCCCCCCCCCCCEEEEEECCHHHHHCCCCCCCCEEEEEEEEECCCCEEEEEECCCCEE
INNIFIKGLVICTKKMKSLRIEPYSGIVEAEAGVMLPTLSNSLAKNGLQGGEWAIGIPGT
EHHHHHHHHHHHHHHHHHEECCCCCCEEECCCCEEEHHHHHHHHHCCCCCCCEEEECCCC
LGGAIYMNAGTGDLSLAKNLISVKVINNKTLETLEIEKKDINFEYRFSSFQSNNLAIISS
CCCEEEEECCCCCHHHHCCEEEEEEECCCCEEEEEEECCCCCEEEEECCCCCCCEEEEEE
KLHFEPNGNLAKLIQKTKNNLKLKTAAQPYHLPSFGSVFKNPENSYAAKLIDDMGLKGFK
EEEECCCCCHHHHHHHHHCCEEEEECCCCCCCCCHHHHHCCCCHHHHHHHHHHCCCCEEE
IGGAEISTMHSNFIINNSSASSKDIYELITVIQQKVLQNKGIYLQPEVRMIGFDYPN
ECCCEEEEEECEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEECCCEEEEEECCCC
>Mature Secondary Structure
MNKKILSENCNLSNYTTIKVGGVAEYFAEPRSIEEFSYLIKWSTLNNHKCQIIGAGSNLL
CCCCCCCCCCCCCCEEEEEECCHHHHHCCCCCCCCEEEEEEEEECCCCEEEEEECCCCEE
INNIFIKGLVICTKKMKSLRIEPYSGIVEAEAGVMLPTLSNSLAKNGLQGGEWAIGIPGT
EHHHHHHHHHHHHHHHHHEECCCCCCEEECCCCEEEHHHHHHHHHCCCCCCCEEEECCCC
LGGAIYMNAGTGDLSLAKNLISVKVINNKTLETLEIEKKDINFEYRFSSFQSNNLAIISS
CCCEEEEECCCCCHHHHCCEEEEEEECCCCEEEEEEECCCCCEEEEECCCCCCCEEEEEE
KLHFEPNGNLAKLIQKTKNNLKLKTAAQPYHLPSFGSVFKNPENSYAAKLIDDMGLKGFK
EEEECCCCCHHHHHHHHHCCEEEEECCCCCCCCCHHHHHCCCCHHHHHHHHHHCCCCEEE
IGGAEISTMHSNFIINNSSASSKDIYELITVIQQKVLQNKGIYLQPEVRMIGFDYPN
ECCCEEEEEECEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEECCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12917642 [H]