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The map label for this gene is thiL [H]

Identifier: 78358609

GI number: 78358609

Start: 3526130

End: 3527149

Strand: Reverse

Name: thiL [H]

Synonym: Dde_3570

Alternate gene names: 78358609

Gene position: 3527149-3526130 (Counterclockwise)

Preceding gene: 78358610

Following gene: 78358608

Centisome position: 94.56

GC content: 64.71

Gene sequence:

>1020_bases
ATGAGCACCATGACTTCCGAAGATGCGTTTCTTGCCTGTATTGACAGGCACTTCTGTAACGAGCACCCGCATATGCTGCG
GGGCAGAGGCGATGATTGCTGCGAACTGGCATGTCCGCCGCGCATGACGCTGAGTACAGACCTGTTCATGCAGGACACCC
ATTTCCGGCTGAGCTATTTTTCCGCAGCGGACATAGGGCACAAGGCGCTGGCTGTGAATATCAGCGATATTGCCGCCGCG
GGCGCCCGGCCGCTGGGATTCAGCATGGGGCTTATGGTGCCGGAAAAGCAGCCGGGGCCGCACCGGCTTACCGGGGCGTT
CTGGGACAGCTTGTTTGACGGCATGGCGCAGCTGGCCCGCAGTCACGGCATGGCACTGACCGGAGGCGACCTGACCCGTG
CGGGTACGTTTGGCCTGTGTGTGACGGTGTGGGGCGGCCCCTGCGGCGATGCGCCTTTTTTGCGGCGCACAGGGTGCAGA
CCCGGCGATGCCGTTTTTCTGGCGGGCGAAGCCGGACTGGCCCGCACCGGCCTGATGGCGCTGGAAGCCATGGGGGCGGA
GGCTGCCGGCGAGTATCCGCATGCTGTGGCGGCTCATCTGAGGCCGGTGCCGCTGGTGCGCAGCGGGCAGCGTCTTGCTG
CTTTGCAGGGGGCACGGCCGCAGTCACGCATCACGTTGATGGATCTTTCCGACGGACTGGCCCGTGACCTGCCGCGTCTT
TTTGCTGCCGGTGAGGGCACCTGCGGTGCCTCGCTGGTTCTGCCCGATGCTTCACTGCATCCAGATGTGCGCCGCTGGGC
CGCAGAGCAGGGTACTGATGCCGCCGTGCATGCGTTCTGCGGCGGAGAAGATTATGCACTGCTGGGCACCTGTGCGCCCG
AAGCCGTGGCCGATGTCATTGAGGCCGCGGCATGCGACGGGGTGCCCGTGCGGGTGCTGGGCACGGTACACGGCGAGCCG
GTTGTCATGCTTAACGGCGTACCGGTTACCGGCGGCGGGTTTGATCATTTTTCCGGTTAA

Upstream 100 bases:

>100_bases
CGGTCTCAAGGTCATTATGGCCCAGTATCTTACTCTGGAATGATAACGGCCCGCTGCCGCGGCCGCCGCAAAATTCACCG
GAACCCACACGGATGCGCAT

Downstream 100 bases:

>100_bases
GATGCGTCATACAGGAGGCTTGCCCCATGACGGCAGAACTGCGCTTTATAGGTGTTGTCCGTTCTTCTCTTAAAGATATC
GGCGATTGCCCCAAACAGGG

Product: thiamine-monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MSTMTSEDAFLACIDRHFCNEHPHMLRGRGDDCCELACPPRMTLSTDLFMQDTHFRLSYFSAADIGHKALAVNISDIAAA
GARPLGFSMGLMVPEKQPGPHRLTGAFWDSLFDGMAQLARSHGMALTGGDLTRAGTFGLCVTVWGGPCGDAPFLRRTGCR
PGDAVFLAGEAGLARTGLMALEAMGAEAAGEYPHAVAAHLRPVPLVRSGQRLAALQGARPQSRITLMDLSDGLARDLPRL
FAAGEGTCGASLVLPDASLHPDVRRWAAEQGTDAAVHAFCGGEDYALLGTCAPEAVADVIEAAACDGVPVRVLGTVHGEP
VVMLNGVPVTGGGFDHFSG

Sequences:

>Translated_339_residues
MSTMTSEDAFLACIDRHFCNEHPHMLRGRGDDCCELACPPRMTLSTDLFMQDTHFRLSYFSAADIGHKALAVNISDIAAA
GARPLGFSMGLMVPEKQPGPHRLTGAFWDSLFDGMAQLARSHGMALTGGDLTRAGTFGLCVTVWGGPCGDAPFLRRTGCR
PGDAVFLAGEAGLARTGLMALEAMGAEAAGEYPHAVAAHLRPVPLVRSGQRLAALQGARPQSRITLMDLSDGLARDLPRL
FAAGEGTCGASLVLPDASLHPDVRRWAAEQGTDAAVHAFCGGEDYALLGTCAPEAVADVIEAAACDGVPVRVLGTVHGEP
VVMLNGVPVTGGGFDHFSG
>Mature_338_residues
STMTSEDAFLACIDRHFCNEHPHMLRGRGDDCCELACPPRMTLSTDLFMQDTHFRLSYFSAADIGHKALAVNISDIAAAG
ARPLGFSMGLMVPEKQPGPHRLTGAFWDSLFDGMAQLARSHGMALTGGDLTRAGTFGLCVTVWGGPCGDAPFLRRTGCRP
GDAVFLAGEAGLARTGLMALEAMGAEAAGEYPHAVAAHLRPVPLVRSGQRLAALQGARPQSRITLMDLSDGLARDLPRLF
AAGEGTCGASLVLPDASLHPDVRRWAAEQGTDAAVHAFCGGEDYALLGTCAPEAVADVIEAAACDGVPVRVLGTVHGEPV
VMLNGVPVTGGGFDHFSG

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=322, Percent_Identity=34.472049689441, Blast_Score=118, Evalue=6e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 35422; Mature: 35291

Theoretical pI: Translated: 5.68; Mature: 5.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
7.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTMTSEDAFLACIDRHFCNEHPHMLRGRGDDCCELACPPRMTLSTDLFMQDTHFRLSYF
CCCCCCCCHHHHHHHHHHCCCCCHHHCCCCCCCEECCCCCCCEECCEEEEECCCEEEEEE
SAADIGHKALAVNISDIAAAGARPLGFSMGLMVPEKQPGPHRLTGAFWDSLFDGMAQLAR
EHHCCCCEEEEEEHHHHHHCCCCCCCEEECEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
SHGMALTGGDLTRAGTFGLCVTVWGGPCGDAPFLRRTGCRPGDAVFLAGEAGLARTGLMA
HCCCEEECCCCCCCCCCEEEEEEECCCCCCCCHHHHCCCCCCCEEEEECCCCCHHHHHHH
LEAMGAEAAGEYPHAVAAHLRPVPLVRSGQRLAALQGARPQSRITLMDLSDGLARDLPRL
HHHHCCHHCCCCCHHHHHHCCCCCCCCCCCCEEHHCCCCCCCEEEEEECCCHHHHHHHHH
FAAGEGTCGASLVLPDASLHPDVRRWAAEQGTDAAVHAFCGGEDYALLGTCAPEAVADVI
HHCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCEEEEEECCCCEEEEECCCHHHHHHHH
EAAACDGVPVRVLGTVHGEPVVMLNGVPVTGGGFDHFSG
HHHHCCCCCEEEEEECCCCCEEEECCEEECCCCCCCCCC
>Mature Secondary Structure 
STMTSEDAFLACIDRHFCNEHPHMLRGRGDDCCELACPPRMTLSTDLFMQDTHFRLSYF
CCCCCCCHHHHHHHHHHCCCCCHHHCCCCCCCEECCCCCCCEECCEEEEECCCEEEEEE
SAADIGHKALAVNISDIAAAGARPLGFSMGLMVPEKQPGPHRLTGAFWDSLFDGMAQLAR
EHHCCCCEEEEEEHHHHHHCCCCCCCEEECEECCCCCCCCCHHHHHHHHHHHHHHHHHHH
SHGMALTGGDLTRAGTFGLCVTVWGGPCGDAPFLRRTGCRPGDAVFLAGEAGLARTGLMA
HCCCEEECCCCCCCCCCEEEEEEECCCCCCCCHHHHCCCCCCCEEEEECCCCCHHHHHHH
LEAMGAEAAGEYPHAVAAHLRPVPLVRSGQRLAALQGARPQSRITLMDLSDGLARDLPRL
HHHHCCHHCCCCCHHHHHHCCCCCCCCCCCCEEHHCCCCCCCEEEEEECCCHHHHHHHHH
FAAGEGTCGASLVLPDASLHPDVRRWAAEQGTDAAVHAFCGGEDYALLGTCAPEAVADVI
HHCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCCEEEEEECCCCEEEEECCCHHHHHHHH
EAAACDGVPVRVLGTVHGEPVVMLNGVPVTGGGFDHFSG
HHHHCCCCCEEEEEECCCCCEEEECCEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9202461; 9384377; 8419296 [H]