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The map label for this gene is pheA [H]

Identifier: 78358526

GI number: 78358526

Start: 3447721

End: 3448860

Strand: Reverse

Name: pheA [H]

Synonym: Dde_3487

Alternate gene names: 78358526

Gene position: 3448860-3447721 (Counterclockwise)

Preceding gene: 78358527

Following gene: 78358525

Centisome position: 92.46

GC content: 57.98

Gene sequence:

>1140_bases
ATGGCAGACGCAGACCGGATTCAGGAACGGATGGGCAGCGTACGTGAAGATATAGACGCCGTGGACAGAGAGCTGCTGGC
CCTTTTGAACAGGCGGGCGGAACTCAGTCTGGAAGTGGGCCGCATAAAGCGCGACGACCCCGGCGTCATATTCAAACCGT
TCCGCGAGCGTGATGTGCTGGAAAAACTGCGCAGCCTCAGCGCAGGCCCGCTGCCGGAAGAACACCTGCGGTCCATATAC
CGCGAGATACTGTCGTCTTCACGCAGTCTGCAGCGTCCTCAGCGTGTGGCCTATCTGGGGCCGGAAGGTACGTTTTCATA
TTTTGCGGGCATTCAGTTTCTGGGGCATTCCGTAGAGTTTCTGCCCCAGAAGGATCTGCATGGTGTCATCCGCTCCGTGC
ACGCCCGCGAATGCGAACTGGGCGTCCTGCCGCTTGAAAATTCGCTGCACGGCACCGTGGGGCAGAGTCTTGATCTGTTT
CTGCGCTACGAGGTGTTCATCAATGCCGAACTGTTCTGTCGTATCAGCCATTCATTGCTGACGGCGGAAAAACGGCTTTC
CGACATCACCACCGTGTATTCGCACCCGCAGCCGCTGGCACAGTGCGGCGAATGGCTGCGGCTTAATCTGCCCGGTGCGC
GTATTATTCCCACCGAATCAACGGCAGCTGCGGCTCGGCGTATCAAAGGCGAAAAGGGCGCTGCGGCCATCGGTCACGGC
AACCTTGCCGAACGTCTGGGACTGAGTGTGCTTGCTTCTGCCATTGAAGACCAGCCCGATAACTGGACCCGGTTTGTGGT
GGTGGGGCCGGTGCCGGCCGACAGGGAAGGCAGGGACAAAACATCCATGCTGTTCACCCTGCCTGACAAATCCGGTTCGC
TGGCGCAGGTGCTCAATATCCTCGCGCGGGAGGATATCAATATGAAAAAGCTGGAATCCCGCCCGTTGCGCGGCGAAAAA
TGGCAGTATGTGTTTTTTGTGGATGTGGAATGCGACCTGAACCATGAAGATTACCGGCAGCTTGTGGACGAGTTGAAGCA
TGTCTGCCACAGCCTGCGGATTCTGGGCAGCTATCCTGCCGGAATGTATTTTGATGTGGCCCGCACGGCCGATGGTTCGG
AACGGCTGGTGACCGAATAG

Upstream 100 bases:

>100_bases
TTGTGGCACTGAAAGAGGGTGATGAAATTCTGGTGCGTACCGATGCTGCGGGCCGGCATTTCGGCATGCGAATTTCCGAA
GAGATAAGGGAAGAGTAGCC

Downstream 100 bases:

>100_bases
TTTTTTTAGCGCACGACGCCCGCAGGGGCGCACAAGCATACGACGGATGAACGCATGAACAGCAAGACCGTAACGGCTCC
GGCCTCCAAATCCGTGTCCC

Product: prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 379; Mature: 378

Protein sequence:

>379_residues
MADADRIQERMGSVREDIDAVDRELLALLNRRAELSLEVGRIKRDDPGVIFKPFRERDVLEKLRSLSAGPLPEEHLRSIY
REILSSSRSLQRPQRVAYLGPEGTFSYFAGIQFLGHSVEFLPQKDLHGVIRSVHARECELGVLPLENSLHGTVGQSLDLF
LRYEVFINAELFCRISHSLLTAEKRLSDITTVYSHPQPLAQCGEWLRLNLPGARIIPTESTAAAARRIKGEKGAAAIGHG
NLAERLGLSVLASAIEDQPDNWTRFVVVGPVPADREGRDKTSMLFTLPDKSGSLAQVLNILAREDINMKKLESRPLRGEK
WQYVFFVDVECDLNHEDYRQLVDELKHVCHSLRILGSYPAGMYFDVARTADGSERLVTE

Sequences:

>Translated_379_residues
MADADRIQERMGSVREDIDAVDRELLALLNRRAELSLEVGRIKRDDPGVIFKPFRERDVLEKLRSLSAGPLPEEHLRSIY
REILSSSRSLQRPQRVAYLGPEGTFSYFAGIQFLGHSVEFLPQKDLHGVIRSVHARECELGVLPLENSLHGTVGQSLDLF
LRYEVFINAELFCRISHSLLTAEKRLSDITTVYSHPQPLAQCGEWLRLNLPGARIIPTESTAAAARRIKGEKGAAAIGHG
NLAERLGLSVLASAIEDQPDNWTRFVVVGPVPADREGRDKTSMLFTLPDKSGSLAQVLNILAREDINMKKLESRPLRGEK
WQYVFFVDVECDLNHEDYRQLVDELKHVCHSLRILGSYPAGMYFDVARTADGSERLVTE
>Mature_378_residues
ADADRIQERMGSVREDIDAVDRELLALLNRRAELSLEVGRIKRDDPGVIFKPFRERDVLEKLRSLSAGPLPEEHLRSIYR
EILSSSRSLQRPQRVAYLGPEGTFSYFAGIQFLGHSVEFLPQKDLHGVIRSVHARECELGVLPLENSLHGTVGQSLDLFL
RYEVFINAELFCRISHSLLTAEKRLSDITTVYSHPQPLAQCGEWLRLNLPGARIIPTESTAAAARRIKGEKGAAAIGHGN
LAERLGLSVLASAIEDQPDNWTRFVVVGPVPADREGRDKTSMLFTLPDKSGSLAQVLNILAREDINMKKLESRPLRGEKW
QYVFFVDVECDLNHEDYRQLVDELKHVCHSLRILGSYPAGMYFDVARTADGSERLVTE

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=370, Percent_Identity=31.6216216216216, Blast_Score=179, Evalue=3e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 42635; Mature: 42504

Theoretical pI: Translated: 6.45; Mature: 6.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADADRIQERMGSVREDIDAVDRELLALLNRRAELSLEVGRIKRDDPGVIFKPFRERDVL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCEEEECCEECCCCCCEECCCHHHHHH
EKLRSLSAGPLPEEHLRSIYREILSSSRSLQRPQRVAYLGPEGTFSYFAGIQFLGHSVEF
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHCCCHHH
LPQKDLHGVIRSVHARECELGVLPLENSLHGTVGQSLDLFLRYEVFINAELFCRISHSLL
CCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHEEEEEEEECHHHHHHHHHHHH
TAEKRLSDITTVYSHPQPLAQCGEWLRLNLPGARIIPTESTAAAARRIKGEKGAAAIGHG
HHHHHHHHHHHHHCCCCHHHHHCCEEEEECCCCEEECCCHHHHHHHHHCCCCCCEEECCC
NLAERLGLSVLASAIEDQPDNWTRFVVVGPVPADREGRDKTSMLFTLPDKSGSLAQVLNI
HHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCEEEEEECCCCCCHHHHHHH
LAREDINMKKLESRPLRGEKWQYVFFVDVECDLNHEDYRQLVDELKHVCHSLRILGSYPA
HHHCCCCHHHHHCCCCCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCC
GMYFDVARTADGSERLVTE
CEEEEEEECCCCCCCCCCC
>Mature Secondary Structure 
ADADRIQERMGSVREDIDAVDRELLALLNRRAELSLEVGRIKRDDPGVIFKPFRERDVL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCEEEECCEECCCCCCEECCCHHHHHH
EKLRSLSAGPLPEEHLRSIYREILSSSRSLQRPQRVAYLGPEGTFSYFAGIQFLGHSVEF
HHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHCCCHHH
LPQKDLHGVIRSVHARECELGVLPLENSLHGTVGQSLDLFLRYEVFINAELFCRISHSLL
CCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHEEEEEEEECHHHHHHHHHHHH
TAEKRLSDITTVYSHPQPLAQCGEWLRLNLPGARIIPTESTAAAARRIKGEKGAAAIGHG
HHHHHHHHHHHHHCCCCHHHHHCCEEEEECCCCEEECCCHHHHHHHHHCCCCCCEEECCC
NLAERLGLSVLASAIEDQPDNWTRFVVVGPVPADREGRDKTSMLFTLPDKSGSLAQVLNI
HHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCCEEEEEECCCCCCHHHHHHH
LAREDINMKKLESRPLRGEKWQYVFFVDVECDLNHEDYRQLVDELKHVCHSLRILGSYPA
HHHCCCCHHHHHCCCCCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCC
GMYFDVARTADGSERLVTE
CEEEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]