Click here to switch to the map view.

The map label for this gene is paaK [H]

Identifier: 78358496

GI number: 78358496

Start: 3417847

End: 3419148

Strand: Reverse

Name: paaK [H]

Synonym: Dde_3457

Alternate gene names: 78358496

Gene position: 3419148-3417847 (Counterclockwise)

Preceding gene: 78358499

Following gene: 78358495

Centisome position: 91.66

GC content: 61.06

Gene sequence:

>1302_bases
ATGTCCCGTTACCGCTTTTTGCCTGATCTTTCAGATGATGCTTTTGCAGCTGTGCAGCTTTCGGGGTTGCAGTGGACCGT
TGAGCATGCCTTGCGCAACAGCCCGTTTTATCGTGGAGTTCTGACTGCTGCCGGTGTGCAGTCCGGCGACATACGGTCGC
TGGACGATCTGCGCCGGCTGCCTTTTACCACCGTGGCAGACCTGCGCGAAGGCTATCCGCTGCCGCTGCTCAGCGTGCCG
GAAAAAGATGTGGTGCGTATCCACGCTTCTTCGGGAACCACGGGCAAGCGCAAGATTCTGGCCTATACAGCCACCGATGT
GGAAAATTTCAAACTGATGATGGCCCGTTGCTACGAGCTTGCCGGTCTGTCTGTGGAAGACAGGGTGCAGATAGCCGTGG
GGTACGGGCTGTGGACGGCCGGTGCGGGGTTTCAGCTGGGGTGCGAACATTTCGGGGCCATGGCCGTGCCTGTGGGGCCT
GGTAATCTGGAAATGCAGCTGCAGCTGCTGACTGATGTGGGCGTGACGTGCCTGTGTTCCACTGCGTCCATGGCTCTGCT
GATGAGTGAAGAAGTGGAGCGCCACGGGCTGCTGGACAGGGTGCGGCTGAAAAAGGTCATATTCGGCGCCGAAGCGCACA
GCCCCAAGATGCGCAAAGCCTTTGAGGAACGGCTGGGGCTGGAAGACAGCTTTGACATTGCCGGTATGACCGAGATGTAC
GGTCCCGGCACCGGGCTTGAGTGCCGCGCCCATGACGGCATCCACTACTGGGCAGACATGTTCATCATAGAAGTGCTGGA
CCCTGTGACGCTGGAACCGGTGGCCCCCGGCGAGGTGGGCGAGATGGTTGTCACATCGCTGCGCAAAGAGGCGGCGCCTC
TTATCCGCTACCGCACCCGCGACCTTACACGCATGTTGCCCGGCAGATGCAGCTGCGGTCTGGACTGCCCGCGGCATGAC
CATATTCTGGGCCGTTCCGACGACATGATTATTTTCCGCGGGGTGAATATTTATCCGGGTCAGATAGCCGACGTGCTGCA
GCAGCATGCGGAACTGGGGGCGGAGTATCAGCTGACGCTGACCCGCCGCGACGGCAGGGACGCCATGCAGCTGCGGGTTG
AACGTGCGCAGGATGCCCCCGGGCTGGGCAGTGAAGGTGAAGCTGCGCTGGTGCGCAGCGTGGCGGACGAGCTGCACCGC
AAGCTTATGGCCCGCTGCGGTGTGGAACTGGCAGCCCACGGTGAGCTGCCTCGTTCCTTTGCCAAATCTAAGCGGGTGGT
GGACTTGCGCGAACAGGAATAG

Upstream 100 bases:

>100_bases
GCCCCGTAGGGGCGCTTTTCGTGGGCACTAGGTACAGTTTTTTCGGCCTGCGGGCAAGCAGGGTATATGTTCCTTTTTCC
GACGCTCAGGGAGTCTAGCC

Downstream 100 bases:

>100_bases
TAAGTAGTGCGTAACTGACATTTTTCTGCCGCGAGATGGGGGTCGGACGGCAGACTCTGCCGCTGCGTGTGCTGCGGCGG
GGTGTTTTCCTTGGTGTGGA

Product: phenylacetate-CoA ligase

Products: NA

Alternate protein names: Phenylacetyl-CoA ligase; PA-CoA ligase [H]

Number of amino acids: Translated: 433; Mature: 432

Protein sequence:

>433_residues
MSRYRFLPDLSDDAFAAVQLSGLQWTVEHALRNSPFYRGVLTAAGVQSGDIRSLDDLRRLPFTTVADLREGYPLPLLSVP
EKDVVRIHASSGTTGKRKILAYTATDVENFKLMMARCYELAGLSVEDRVQIAVGYGLWTAGAGFQLGCEHFGAMAVPVGP
GNLEMQLQLLTDVGVTCLCSTASMALLMSEEVERHGLLDRVRLKKVIFGAEAHSPKMRKAFEERLGLEDSFDIAGMTEMY
GPGTGLECRAHDGIHYWADMFIIEVLDPVTLEPVAPGEVGEMVVTSLRKEAAPLIRYRTRDLTRMLPGRCSCGLDCPRHD
HILGRSDDMIIFRGVNIYPGQIADVLQQHAELGAEYQLTLTRRDGRDAMQLRVERAQDAPGLGSEGEAALVRSVADELHR
KLMARCGVELAAHGELPRSFAKSKRVVDLREQE

Sequences:

>Translated_433_residues
MSRYRFLPDLSDDAFAAVQLSGLQWTVEHALRNSPFYRGVLTAAGVQSGDIRSLDDLRRLPFTTVADLREGYPLPLLSVP
EKDVVRIHASSGTTGKRKILAYTATDVENFKLMMARCYELAGLSVEDRVQIAVGYGLWTAGAGFQLGCEHFGAMAVPVGP
GNLEMQLQLLTDVGVTCLCSTASMALLMSEEVERHGLLDRVRLKKVIFGAEAHSPKMRKAFEERLGLEDSFDIAGMTEMY
GPGTGLECRAHDGIHYWADMFIIEVLDPVTLEPVAPGEVGEMVVTSLRKEAAPLIRYRTRDLTRMLPGRCSCGLDCPRHD
HILGRSDDMIIFRGVNIYPGQIADVLQQHAELGAEYQLTLTRRDGRDAMQLRVERAQDAPGLGSEGEAALVRSVADELHR
KLMARCGVELAAHGELPRSFAKSKRVVDLREQE
>Mature_432_residues
SRYRFLPDLSDDAFAAVQLSGLQWTVEHALRNSPFYRGVLTAAGVQSGDIRSLDDLRRLPFTTVADLREGYPLPLLSVPE
KDVVRIHASSGTTGKRKILAYTATDVENFKLMMARCYELAGLSVEDRVQIAVGYGLWTAGAGFQLGCEHFGAMAVPVGPG
NLEMQLQLLTDVGVTCLCSTASMALLMSEEVERHGLLDRVRLKKVIFGAEAHSPKMRKAFEERLGLEDSFDIAGMTEMYG
PGTGLECRAHDGIHYWADMFIIEVLDPVTLEPVAPGEVGEMVVTSLRKEAAPLIRYRTRDLTRMLPGRCSCGLDCPRHDH
ILGRSDDMIIFRGVNIYPGQIADVLQQHAELGAEYQLTLTRRDGRDAMQLRVERAQDAPGLGSEGEAALVRSVADELHRK
LMARCGVELAAHGELPRSFAKSKRVVDLREQE

Specific function: Catalyzes the activation of phenylacetic acid to phenylacetyl-CoA [H]

COG id: COG1541

COG function: function code H; Coenzyme F390 synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1787664, Length=424, Percent_Identity=41.0377358490566, Blast_Score=313, Evalue=1e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000873
- InterPro:   IPR011880 [H]

Pfam domain/function: PF00501 AMP-binding [H]

EC number: =6.2.1.30 [H]

Molecular weight: Translated: 47812; Mature: 47680

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRYRFLPDLSDDAFAAVQLSGLQWTVEHALRNSPFYRGVLTAAGVQSGDIRSLDDLRRL
CCCCCCCCCCCCCCEEEEEECCCHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCHHHHHHC
PFTTVADLREGYPLPLLSVPEKDVVRIHASSGTTGKRKILAYTATDVENFKLMMARCYEL
CCHHHHHHHCCCCCCEECCCCCCEEEEECCCCCCCCEEEEEEEECCHHHHHHHHHHHHHH
AGLSVEDRVQIAVGYGLWTAGAGFQLGCEHFGAMAVPVGPGNLEMQLQLLTDVGVTCLCS
CCCCCCCCEEEEEEECEEECCCCCEECHHHCCCEEEEECCCCCEEEEEEEHHCCHHHHHH
TASMALLMSEEVERHGLLDRVRLKKVIFGAEAHSPKMRKAFEERLGLEDSFDIAGMTEMY
HHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHC
GPGTGLECRAHDGIHYWADMFIIEVLDPVTLEPVAPGEVGEMVVTSLRKEAAPLIRYRTR
CCCCCCEEEECCCHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
DLTRMLPGRCSCGLDCPRHDHILGRSDDMIIFRGVNIYPGQIADVLQQHAELGAEYQLTL
HHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEE
TRRDGRDAMQLRVERAQDAPGLGSEGEAALVRSVADELHRKLMARCGVELAAHGELPRSF
EECCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHH
AKSKRVVDLREQE
HHCCCCCCCCCCC
>Mature Secondary Structure 
SRYRFLPDLSDDAFAAVQLSGLQWTVEHALRNSPFYRGVLTAAGVQSGDIRSLDDLRRL
CCCCCCCCCCCCCEEEEEECCCHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCHHHHHHC
PFTTVADLREGYPLPLLSVPEKDVVRIHASSGTTGKRKILAYTATDVENFKLMMARCYEL
CCHHHHHHHCCCCCCEECCCCCCEEEEECCCCCCCCEEEEEEEECCHHHHHHHHHHHHHH
AGLSVEDRVQIAVGYGLWTAGAGFQLGCEHFGAMAVPVGPGNLEMQLQLLTDVGVTCLCS
CCCCCCCCEEEEEEECEEECCCCCEECHHHCCCEEEEECCCCCEEEEEEEHHCCHHHHHH
TASMALLMSEEVERHGLLDRVRLKKVIFGAEAHSPKMRKAFEERLGLEDSFDIAGMTEMY
HHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHC
GPGTGLECRAHDGIHYWADMFIIEVLDPVTLEPVAPGEVGEMVVTSLRKEAAPLIRYRTR
CCCCCCEEEECCCHHHHHHHHHHHHHCCCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
DLTRMLPGRCSCGLDCPRHDHILGRSDDMIIFRGVNIYPGQIADVLQQHAELGAEYQLTL
HHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCEEEEEE
TRRDGRDAMQLRVERAQDAPGLGSEGEAALVRSVADELHRKLMARCGVELAAHGELPRSF
EECCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEECCCCHHHH
AKSKRVVDLREQE
HHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9748275; 9278503; 10766858 [H]