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The map label for this gene is hsdM [C]

Identifier: 78358466

GI number: 78358466

Start: 3391090

End: 3392604

Strand: Reverse

Name: hsdM [C]

Synonym: Dde_3427

Alternate gene names: 78358466

Gene position: 3392604-3391090 (Counterclockwise)

Preceding gene: 78358467

Following gene: 78358465

Centisome position: 90.95

GC content: 60.86

Gene sequence:

>1515_bases
ATGAAGAAAAGCAAACACATTTCCCAATCGGAGCTGGAATCCTACCTCTGGGGCGCGGCCACCTTGCTGCGCGGCTACAT
CGACGCCGGGGACTACAAGCAGTTCATCTTCCCGCTGCTGTTCTACAAGCGCCTATGCGACGTCTATGACGAGGAGCTGG
CCGATGCGCTGGAGGAATCCGGCGGCGATCAGGAATACGCCGCGCTTCCCGAACAGCACCGCTTCCAGATCCCGGAAGAC
GCTCACTGGAAGGCCACCCGAACCAAGGTCAAGAACGTGGGAAAGGCCATTCAGGATGCCTTGCGGGCCATTGAGACGGC
CAATCCCGACACTCTGTACGGGGTCTTCGGTGACGCCCAGTGGACCAACAAGGACCGTCTGCCGGATCGCATGCTGCGCG
AGCTGATCGAGCATTTCAGCTCGCAGACGCTTTCGCTCTCCAACTGCCCGGAGGATGAGCTGGGCGTGGGTTACGAGTTT
CTGATCAAGAAGTTCGCCGACGATTCCGGCCACACCGCTGCGGAGTTCTATACCAACCGCACCGTGGTCCATCTGATGAC
CGAGATGCTCGAACCCAAACCGGGTGAGTCGATCTATGACCCCACCTGCGGTTCGGCGGGCATGCTGCTCTCCGCCGTCG
CCCATCTGAAGCGGCAGAACAAGGAGTGGCGGAACCTGCGGCTGTTCGGCCAGGAGCGCAACCTGCTCACCTCGGCCATC
GGCCGGATGAACCTGTTCCTGCACGGCATCGAGGACTTCCGCATCGTCCGGGGTGACACCCTGGCCAACCCCGCCTTTGT
CGAAGGCGACCGGCTCATGCAGTTCGATGTGGTGCTGGCCAATCCGCCGTACTCCATCAAACAGTGGGATCGCGATGCCT
GGTCCGCCGATCCGTGGGGCCGGAATATCTACGGCACCCCGCCCCAGGGCCGCGCCGACTATGCCTTCTGGCAGCACATC
ATCAAGAGCATGAAGGCCAAGAGTGGTCGCTGCGCCATCCTGTTTCCGCATGGCGTCCTCTTCCGCAATGAAGAGTCGGC
CATGCGTGAGAAGCTGGTCGCCCACGACGTGGTGGAGTGTGTGCTGGGCCTCGGTCCCAACCTCTTTTACAACTCGCCCA
TGGAAGCCTGCGTCGTCATCTGCCGGATGAACAAACCCAAGGAGCGCAGGAACAAGGTGCTCTTCATCAACGCGGTGAAC
GAAGTGACCCGCGAGCGGGCACAGAGCTTCCTCACCGACGACCACATCCAGCGCATTGTCGCCGCCTACCAGGCTTTCGG
TGACGAGGACGGCTTTGCCCGGGTGGTCGGCAATGACGAGATCCGGGAGAAAGCCAGCAATCTCAGCATCCCGCTCTACG
TGAGGGCGGAAAACGGAAATGGCAATGGCAACGGCTCGACCGAAACGGTCAGCCTCAAACAGGCCATTGCGAACTGGCAG
GAAAGCTCGATGGCATTGCGGGAGTCGATGGACGGCCTGCTTTCATCATTAGAGGGAGGGCTGCATGGAAGCTAA

Upstream 100 bases:

>100_bases
CCGATGACGTCTACATGCAGGCGACCGGCGATTACGACTGGGACTCCCTGGATGGCGTCGATATTCCAACGGACATTTCT
GAATGGGAAGTGGTAGCGCG

Downstream 100 bases:

>100_bases
GACGCCTTTCTCTCAAGAGGATCTGAACGAAATCTTCAAGATTTCCCCTGCAGATCCGGAACGCGTGATTTCAAGGGAAA
GCAGCAGCCTTGAATTCAAG

Product: type I restriction-modification system methylation subunit-like

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 504; Mature: 504

Protein sequence:

>504_residues
MKKSKHISQSELESYLWGAATLLRGYIDAGDYKQFIFPLLFYKRLCDVYDEELADALEESGGDQEYAALPEQHRFQIPED
AHWKATRTKVKNVGKAIQDALRAIETANPDTLYGVFGDAQWTNKDRLPDRMLRELIEHFSSQTLSLSNCPEDELGVGYEF
LIKKFADDSGHTAAEFYTNRTVVHLMTEMLEPKPGESIYDPTCGSAGMLLSAVAHLKRQNKEWRNLRLFGQERNLLTSAI
GRMNLFLHGIEDFRIVRGDTLANPAFVEGDRLMQFDVVLANPPYSIKQWDRDAWSADPWGRNIYGTPPQGRADYAFWQHI
IKSMKAKSGRCAILFPHGVLFRNEESAMREKLVAHDVVECVLGLGPNLFYNSPMEACVVICRMNKPKERRNKVLFINAVN
EVTRERAQSFLTDDHIQRIVAAYQAFGDEDGFARVVGNDEIREKASNLSIPLYVRAENGNGNGNGSTETVSLKQAIANWQ
ESSMALRESMDGLLSSLEGGLHGS

Sequences:

>Translated_504_residues
MKKSKHISQSELESYLWGAATLLRGYIDAGDYKQFIFPLLFYKRLCDVYDEELADALEESGGDQEYAALPEQHRFQIPED
AHWKATRTKVKNVGKAIQDALRAIETANPDTLYGVFGDAQWTNKDRLPDRMLRELIEHFSSQTLSLSNCPEDELGVGYEF
LIKKFADDSGHTAAEFYTNRTVVHLMTEMLEPKPGESIYDPTCGSAGMLLSAVAHLKRQNKEWRNLRLFGQERNLLTSAI
GRMNLFLHGIEDFRIVRGDTLANPAFVEGDRLMQFDVVLANPPYSIKQWDRDAWSADPWGRNIYGTPPQGRADYAFWQHI
IKSMKAKSGRCAILFPHGVLFRNEESAMREKLVAHDVVECVLGLGPNLFYNSPMEACVVICRMNKPKERRNKVLFINAVN
EVTRERAQSFLTDDHIQRIVAAYQAFGDEDGFARVVGNDEIREKASNLSIPLYVRAENGNGNGNGSTETVSLKQAIANWQ
ESSMALRESMDGLLSSLEGGLHGS
>Mature_504_residues
MKKSKHISQSELESYLWGAATLLRGYIDAGDYKQFIFPLLFYKRLCDVYDEELADALEESGGDQEYAALPEQHRFQIPED
AHWKATRTKVKNVGKAIQDALRAIETANPDTLYGVFGDAQWTNKDRLPDRMLRELIEHFSSQTLSLSNCPEDELGVGYEF
LIKKFADDSGHTAAEFYTNRTVVHLMTEMLEPKPGESIYDPTCGSAGMLLSAVAHLKRQNKEWRNLRLFGQERNLLTSAI
GRMNLFLHGIEDFRIVRGDTLANPAFVEGDRLMQFDVVLANPPYSIKQWDRDAWSADPWGRNIYGTPPQGRADYAFWQHI
IKSMKAKSGRCAILFPHGVLFRNEESAMREKLVAHDVVECVLGLGPNLFYNSPMEACVVICRMNKPKERRNKVLFINAVN
EVTRERAQSFLTDDHIQRIVAAYQAFGDEDGFARVVGNDEIREKASNLSIPLYVRAENGNGNGNGSTETVSLKQAIANWQ
ESSMALRESMDGLLSSLEGGLHGS

Specific function: The M And S Subunits Together Form A Methyltransferase (Mtase) That Methylates Two Adenine Residues In Complementary Strands Of A Bipartite DNA Recognition Sequence. In The Presence Of The R Subunit The Complex Can Also Act As An Endonuclease, Binding To

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790808, Length=293, Percent_Identity=25.938566552901, Blast_Score=87, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022749
- InterPro:   IPR003356
- InterPro:   IPR002052
- InterPro:   IPR002296
- InterPro:   IPR011991 [H]

Pfam domain/function: PF12161 HsdM_N; PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 56855; Mature: 56855

Theoretical pI: Translated: 5.80; Mature: 5.80

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKSKHISQSELESYLWGAATLLRGYIDAGDYKQFIFPLLFYKRLCDVYDEELADALEES
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GGDQEYAALPEQHRFQIPEDAHWKATRTKVKNVGKAIQDALRAIETANPDTLYGVFGDAQ
CCCCHHHHCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
WTNKDRLPDRMLRELIEHFSSQTLSLSNCPEDELGVGYEFLIKKFADDSGHTAAEFYTNR
CCCCCCCHHHHHHHHHHHHCCCCEECCCCCCHHHCCCHHHHHHHHCCCCCCCHHHHHCCC
TVVHLMTEMLEPKPGESIYDPTCGSAGMLLSAVAHLKRQNKEWRNLRLFGQERNLLTSAI
HHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHEEEECHHHHHHHHHH
GRMNLFLHGIEDFRIVRGDTLANPAFVEGDRLMQFDVVLANPPYSIKQWDRDAWSADPWG
HHHHHHHCCCCHHEEECCCCCCCCCEECCCCEEEEEEEEECCCCHHHHHCCCCCCCCCCC
RNIYGTPPQGRADYAFWQHIIKSMKAKSGRCAILFPHGVLFRNEESAMREKLVAHDVVEC
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCEEEECHHHHHHHHHHHHHHHHH
VLGLGPNLFYNSPMEACVVICRMNKPKERRNKVLFINAVNEVTRERAQSFLTDDHIQRIV
HHHCCCCCCCCCCHHHHHHHHCCCCCHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHH
AAYQAFGDEDGFARVVGNDEIREKASNLSIPLYVRAENGNGNGNGSTETVSLKQAIANWQ
HHHHHHCCCCCEEEECCCHHHHHHHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHH
ESSMALRESMDGLLSSLEGGLHGS
HHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKKSKHISQSELESYLWGAATLLRGYIDAGDYKQFIFPLLFYKRLCDVYDEELADALEES
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GGDQEYAALPEQHRFQIPEDAHWKATRTKVKNVGKAIQDALRAIETANPDTLYGVFGDAQ
CCCCHHHHCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCC
WTNKDRLPDRMLRELIEHFSSQTLSLSNCPEDELGVGYEFLIKKFADDSGHTAAEFYTNR
CCCCCCCHHHHHHHHHHHHCCCCEECCCCCCHHHCCCHHHHHHHHCCCCCCCHHHHHCCC
TVVHLMTEMLEPKPGESIYDPTCGSAGMLLSAVAHLKRQNKEWRNLRLFGQERNLLTSAI
HHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHEEEECHHHHHHHHHH
GRMNLFLHGIEDFRIVRGDTLANPAFVEGDRLMQFDVVLANPPYSIKQWDRDAWSADPWG
HHHHHHHCCCCHHEEECCCCCCCCCEECCCCEEEEEEEEECCCCHHHHHCCCCCCCCCCC
RNIYGTPPQGRADYAFWQHIIKSMKAKSGRCAILFPHGVLFRNEESAMREKLVAHDVVEC
CCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCEEEECHHHHHHHHHHHHHHHHH
VLGLGPNLFYNSPMEACVVICRMNKPKERRNKVLFINAVNEVTRERAQSFLTDDHIQRIV
HHHCCCCCCCCCCHHHHHHHHCCCCCHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHH
AAYQAFGDEDGFARVVGNDEIREKASNLSIPLYVRAENGNGNGNGSTETVSLKQAIANWQ
HHHHHHCCCCCEEEECCCHHHHHHHHCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHH
ESSMALRESMDGLLSSLEGGLHGS
HHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]