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The map label for this gene is hsdS [H]

Identifier: 78358464

GI number: 78358464

Start: 3388615

End: 3389787

Strand: Reverse

Name: hsdS [H]

Synonym: Dde_3425

Alternate gene names: 78358464

Gene position: 3389787-3388615 (Counterclockwise)

Preceding gene: 78358465

Following gene: 78358463

Centisome position: 90.87

GC content: 52.6

Gene sequence:

>1173_bases
ATGAGCACACAATCCCTGAAGCCCGGCTGGAAGATGGTGAAGTTCGGCGAGGTGGTGAAGAACGCCAACCTCGTGGAGCG
TGAGCCCGAGGCCAATGGCGTTGAAAAAATCGTCGGGCTTGAACACATCGACCCCGAGAATCTGCATGTCCGGCGCTGGA
ACTCTGTTGTGGATGGCACCTCGTTTACCCGCAAATTCGTGCCGGGGCAGACGCTCTTCGGCAAGCGCCGGGCTTATCAA
CGCAAGGTCGCCTATGCCGAGTTTGAAGGTATTTGCTCCGGGGATATCCTGACGTTCGAGCCGAAAAACAGAAAGGTTCT
GCTGCCGGAACTTCTGCCGTTTATCTGCCAGAGTGATGCCTTTTTCGATCATGCGCTTGATACCTCGGCCGGATCGCTGT
CGCCGAGAACCAGTTGGACGGCATTGAAGGACTTTGAATTCCCGCTGCCGCCCATTGATGAGCAGAAGCGTATTGCCGAG
ATCCTGTGGGCTGCGGATGAGGCGGTGGAGCAATGGACGGAAGCTTATCGACAGGCTGAATTAGCCCTGAATTCAACGCG
GAGCCAGATCCTTCAAGAGCTTTCTCAGACGGAAGTATGTGTCTCCTTAAAAGATGTTGGCCGATGGGTTAGTGGTGGAA
CGCCATCACGCAGCCGAAGTGATTTCTGGAATGGCGATTTTCCGTGGGTCAGCCCGAAGGATATGAAGCAGGATGTCATA
TCCGACTCCGAGGAGAAACTTACTGATACAGCTTTGAATGGGCGAGTAACCATCCTGCCTTCGGAAAGCATTCTCATAGT
TGTTCGCGGGATGATTCTTGCCCACACATTCCCGGTCGCACTCACCGGCAGGGAGGTTACGTTCAATCAGGATATGAAGG
GCATTATCCCCAACTCTGATTTTTCGGCTGAATTTGTATTTCACTGGTTCAAAGACAATTCCACAAGAATTCTGCAAGCA
ACAGAAGAGAGCACGCACGGCACAAAGCGCCTTGCAACGGATGTCTTGTACGGGATGCAAATACCTAAACCATCGCCGGC
AAAGCAGGAAATGGCAGTGACTGTCTTCGAAACTTTTCGCACCAAGCTGGCTGAAATTTCGGAGCATATCGCCTCTTCTC
AGCAGATGTTGCGCAGTCTGAGGAATGCAAAAGCAGGAGCCGCCCATGTTTAA

Upstream 100 bases:

>100_bases
GGTTTAACAAACACTACGCATCGGCCAAAGGCCCACTGGCTGACAACCTGCGACGGGCGATCTGCTGGGTTGATGAAGCA
TTGAATATGGGAGACTGTAA

Downstream 100 bases:

>100_bases
CGAAGAAAACACGGTCGAACAGATGGTCCTCGACACGCTCTGTGGCGGCGTGACTTCGAACATGGTTGCCGAAGAGCTCG
CCAGCTACGGCGGTGAAATC

Product: restriction endonuclease S subunits-like

Products: NA

Alternate protein names: S.EcoR124II; Type I restriction enzyme EcoR124II specificity protein; S protein [H]

Number of amino acids: Translated: 390; Mature: 389

Protein sequence:

>390_residues
MSTQSLKPGWKMVKFGEVVKNANLVEREPEANGVEKIVGLEHIDPENLHVRRWNSVVDGTSFTRKFVPGQTLFGKRRAYQ
RKVAYAEFEGICSGDILTFEPKNRKVLLPELLPFICQSDAFFDHALDTSAGSLSPRTSWTALKDFEFPLPPIDEQKRIAE
ILWAADEAVEQWTEAYRQAELALNSTRSQILQELSQTEVCVSLKDVGRWVSGGTPSRSRSDFWNGDFPWVSPKDMKQDVI
SDSEEKLTDTALNGRVTILPSESILIVVRGMILAHTFPVALTGREVTFNQDMKGIIPNSDFSAEFVFHWFKDNSTRILQA
TEESTHGTKRLATDVLYGMQIPKPSPAKQEMAVTVFETFRTKLAEISEHIASSQQMLRSLRNAKAGAAHV

Sequences:

>Translated_390_residues
MSTQSLKPGWKMVKFGEVVKNANLVEREPEANGVEKIVGLEHIDPENLHVRRWNSVVDGTSFTRKFVPGQTLFGKRRAYQ
RKVAYAEFEGICSGDILTFEPKNRKVLLPELLPFICQSDAFFDHALDTSAGSLSPRTSWTALKDFEFPLPPIDEQKRIAE
ILWAADEAVEQWTEAYRQAELALNSTRSQILQELSQTEVCVSLKDVGRWVSGGTPSRSRSDFWNGDFPWVSPKDMKQDVI
SDSEEKLTDTALNGRVTILPSESILIVVRGMILAHTFPVALTGREVTFNQDMKGIIPNSDFSAEFVFHWFKDNSTRILQA
TEESTHGTKRLATDVLYGMQIPKPSPAKQEMAVTVFETFRTKLAEISEHIASSQQMLRSLRNAKAGAAHV
>Mature_389_residues
STQSLKPGWKMVKFGEVVKNANLVEREPEANGVEKIVGLEHIDPENLHVRRWNSVVDGTSFTRKFVPGQTLFGKRRAYQR
KVAYAEFEGICSGDILTFEPKNRKVLLPELLPFICQSDAFFDHALDTSAGSLSPRTSWTALKDFEFPLPPIDEQKRIAEI
LWAADEAVEQWTEAYRQAELALNSTRSQILQELSQTEVCVSLKDVGRWVSGGTPSRSRSDFWNGDFPWVSPKDMKQDVIS
DSEEKLTDTALNGRVTILPSESILIVVRGMILAHTFPVALTGREVTFNQDMKGIIPNSDFSAEFVFHWFKDNSTRILQAT
EESTHGTKRLATDVLYGMQIPKPSPAKQEMAVTVFETFRTKLAEISEHIASSQQMLRSLRNAKAGAAHV

Specific function: The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. In the presence of the R subunit the complex can also act as an endonuclease, binding to

COG id: COG0732

COG function: function code V; Restriction endonuclease S subunits

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I restriction system S methylase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000055 [H]

Pfam domain/function: PF01420 Methylase_S [H]

EC number: NA

Molecular weight: Translated: 43847; Mature: 43716

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTQSLKPGWKMVKFGEVVKNANLVEREPEANGVEKIVGLEHIDPENLHVRRWNSVVDGT
CCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCCCEEEECCCHHCCC
SFTRKFVPGQTLFGKRRAYQRKVAYAEFEGICSGDILTFEPKNRKVLLPELLPFICQSDA
HHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEHHHHHHHHHCCCC
FFDHALDTSAGSLSPRTSWTALKDFEFPLPPIDEQKRIAEILWAADEAVEQWTEAYRQAE
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LALNSTRSQILQELSQTEVCVSLKDVGRWVSGGTPSRSRSDFWNGDFPWVSPKDMKQDVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
SDSEEKLTDTALNGRVTILPSESILIVVRGMILAHTFPVALTGREVTFNQDMKGIIPNSD
CCCHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHCCEEEECCEEEECCCCCCCCCCCC
FSAEFVFHWFKDNSTRILQATEESTHGTKRLATDVLYGMQIPKPSPAKQEMAVTVFETFR
CCCEEEEEEECCCCCEEEEECCHHCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
TKLAEISEHIASSQQMLRSLRNAKAGAAHV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
STQSLKPGWKMVKFGEVVKNANLVEREPEANGVEKIVGLEHIDPENLHVRRWNSVVDGT
CCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCCCCCCCCEEEECCCHHCCC
SFTRKFVPGQTLFGKRRAYQRKVAYAEFEGICSGDILTFEPKNRKVLLPELLPFICQSDA
HHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEHHHHHHHHHCCCC
FFDHALDTSAGSLSPRTSWTALKDFEFPLPPIDEQKRIAEILWAADEAVEQWTEAYRQAE
HHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LALNSTRSQILQELSQTEVCVSLKDVGRWVSGGTPSRSRSDFWNGDFPWVSPKDMKQDVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
SDSEEKLTDTALNGRVTILPSESILIVVRGMILAHTFPVALTGREVTFNQDMKGIIPNSD
CCCHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHCCEEEECCEEEECCCCCCCCCCCC
FSAEFVFHWFKDNSTRILQATEESTHGTKRLATDVLYGMQIPKPSPAKQEMAVTVFETFR
CCCEEEEEEECCCCCEEEEECCHHCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
TKLAEISEHIASSQQMLRSLRNAKAGAAHV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2784505 [H]