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The map label for this gene is lldD [H]

Identifier: 78355797

GI number: 78355797

Start: 776722

End: 777744

Strand: Direct

Name: lldD [H]

Synonym: Dde_0750

Alternate gene names: 78355797

Gene position: 776722-777744 (Clockwise)

Preceding gene: 78355796

Following gene: 78355798

Centisome position: 20.82

GC content: 61.97

Gene sequence:

>1023_bases
ATGAAGGAAGTACGCGAAAAGGCAAAAGAACTGATGAAAGGCTATTGCCGGGTCTGTCCCGTGTGCAACGGCAAGGCCTG
CGCGGGCGAAGTGCCCGGCATGGGCGGACTGAACACCGCCTCTTCTTTCCGCAACAATGTGGAATCGCTGGCGGCCGTGC
AGCTGAACATGCGCCTTATCCATGATGCCGTGCAGCCCGACACCTCGGTGACCGTGCTTGGTATTCCTCTTTCCATGCCT
GTCATGGCTGCGCCCATCGGAGGAGTCTCCTTCAACATGGGCGGCGGCATCACCGAAGAAGAGTATGTGAACGCCATTCT
GGGCGGCTGCAGACAGCAGGGAGTCATAGGCTGTACGGGCGACGGGGTGCCTCCGTTCATCATCGACGCCGGCATGGACG
GCATTGCGGCGGTGGAAGGGCACGGTATTCCGTTCATCAAGCCGTGGGACGGGGAAGAGCTTGACCAGAAGCTTGACCGG
GCGCTTGCTTCGGCCTGTCCTGCTGTGGGTATGGATATCGATGCCGCGGGGCTGGTTACGCTGCGCAAGATGGGCAGACC
TGTGTCGCCCAAAACACCGGCGCAGCTGAAAGCCGTTGTGGACAAAGTGCACGCGGCAGGCCGGACGTTTATCCTGAAGG
GCATCATGACGGTGGTGGATGCCCAGCTGGCGGTGGAAGTGGGTGCCGACGCCATTGTGGTTTCCAACCACGGCGGGCGC
GTGCTTGACCATACGCCGGGTGCCGCGGAAGTGCTGCCCGAAATCGCCGATGCCGTGAAGGGCCGCATTACCGTGCTGGC
GGACGGCGGTGTGCGTGACGGGTTTGATGTGATCAAAATGCTTGCTCTGGGCGCCGATGCCGTGCTTATCGGACGTCCTT
TCAGCATTGCCGCGGTGGGCGGTCAGGCCGAAGGCGTGGCTGCATACCTTGAAGCGCTGCGCGGCCAGCTTGTGCAGGCC
ATGGTGCTTACAGGCTGCCGCAGCGTGCAGGAAGCCGGACGGCATATACTGCGCGGAATCTGA

Upstream 100 bases:

>100_bases
TTCAGAAGGGCTGCCGCGCAACGCGGCGTGCCGCAGGCAGGGTGTCCGCACACACTCATCACACAAATGCCGCCACGACG
GCCAAGGAGGATTCTCCGGC

Downstream 100 bases:

>100_bases
TGCAGAATACGGCCCGCGGCATGCTGTCGCGGGCTTTTTTTAACGGACGGCGGGCTTACTATCATGATAGAATCTCTTGC
TCTTTACATCGCGCTTGGTT

Product: FMN-dependent family dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MKEVREKAKELMKGYCRVCPVCNGKACAGEVPGMGGLNTASSFRNNVESLAAVQLNMRLIHDAVQPDTSVTVLGIPLSMP
VMAAPIGGVSFNMGGGITEEEYVNAILGGCRQQGVIGCTGDGVPPFIIDAGMDGIAAVEGHGIPFIKPWDGEELDQKLDR
ALASACPAVGMDIDAAGLVTLRKMGRPVSPKTPAQLKAVVDKVHAAGRTFILKGIMTVVDAQLAVEVGADAIVVSNHGGR
VLDHTPGAAEVLPEIADAVKGRITVLADGGVRDGFDVIKMLALGADAVLIGRPFSIAAVGGQAEGVAAYLEALRGQLVQA
MVLTGCRSVQEAGRHILRGI

Sequences:

>Translated_340_residues
MKEVREKAKELMKGYCRVCPVCNGKACAGEVPGMGGLNTASSFRNNVESLAAVQLNMRLIHDAVQPDTSVTVLGIPLSMP
VMAAPIGGVSFNMGGGITEEEYVNAILGGCRQQGVIGCTGDGVPPFIIDAGMDGIAAVEGHGIPFIKPWDGEELDQKLDR
ALASACPAVGMDIDAAGLVTLRKMGRPVSPKTPAQLKAVVDKVHAAGRTFILKGIMTVVDAQLAVEVGADAIVVSNHGGR
VLDHTPGAAEVLPEIADAVKGRITVLADGGVRDGFDVIKMLALGADAVLIGRPFSIAAVGGQAEGVAAYLEALRGQLVQA
MVLTGCRSVQEAGRHILRGI
>Mature_340_residues
MKEVREKAKELMKGYCRVCPVCNGKACAGEVPGMGGLNTASSFRNNVESLAAVQLNMRLIHDAVQPDTSVTVLGIPLSMP
VMAAPIGGVSFNMGGGITEEEYVNAILGGCRQQGVIGCTGDGVPPFIIDAGMDGIAAVEGHGIPFIKPWDGEELDQKLDR
ALASACPAVGMDIDAAGLVTLRKMGRPVSPKTPAQLKAVVDKVHAAGRTFILKGIMTVVDAQLAVEVGADAIVVSNHGGR
VLDHTPGAAEVLPEIADAVKGRITVLADGGVRDGFDVIKMLALGADAVLIGRPFSIAAVGGQAEGVAAYLEALRGQLVQA
MVLTGCRSVQEAGRHILRGI

Specific function: Unknown

COG id: COG1304

COG function: function code C; L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FMN hydroxy acid dehydrogenase domain [H]

Homologues:

Organism=Homo sapiens, GI54234014, Length=326, Percent_Identity=28.5276073619632, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI7705393, Length=326, Percent_Identity=28.5276073619632, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI11068137, Length=128, Percent_Identity=45.3125, Blast_Score=106, Evalue=4e-23,
Organism=Escherichia coli, GI1790033, Length=122, Percent_Identity=54.9180327868852, Blast_Score=119, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI193208036, Length=121, Percent_Identity=47.1074380165289, Blast_Score=105, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6323587, Length=132, Percent_Identity=38.6363636363636, Blast_Score=83, Evalue=6e-17,
Organism=Drosophila melanogaster, GI281363140, Length=119, Percent_Identity=41.1764705882353, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI78707190, Length=119, Percent_Identity=41.1764705882353, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI78707188, Length=119, Percent_Identity=41.1764705882353, Blast_Score=94, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR012133
- InterPro:   IPR000262
- InterPro:   IPR008259
- InterPro:   IPR020920 [H]

Pfam domain/function: PF01070 FMN_dh [H]

EC number: =1.1.2.3 [H]

Molecular weight: Translated: 35088; Mature: 35088

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEVREKAKELMKGYCRVCPVCNGKACAGEVPGMGGLNTASSFRNNVESLAAVQLNMRLI
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
HDAVQPDTSVTVLGIPLSMPVMAAPIGGVSFNMGGGITEEEYVNAILGGCRQQGVIGCTG
HHHHCCCCCEEEEECCCCCCHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCEEECC
DGVPPFIIDAGMDGIAAVEGHGIPFIKPWDGEELDQKLDRALASACPAVGMDIDAAGLVT
CCCCCEEEECCCCCEEEECCCCCCEECCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
LRKMGRPVSPKTPAQLKAVVDKVHAAGRTFILKGIMTVVDAQLAVEVGADAIVVSNHGGR
HHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCE
VLDHTPGAAEVLPEIADAVKGRITVLADGGVRDGFDVIKMLALGADAVLIGRPFSIAAVG
EEECCCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCEEEECCCEEEEEEC
GQAEGVAAYLEALRGQLVQAMVLTGCRSVQEAGRHILRGI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKEVREKAKELMKGYCRVCPVCNGKACAGEVPGMGGLNTASSFRNNVESLAAVQLNMRLI
CHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
HDAVQPDTSVTVLGIPLSMPVMAAPIGGVSFNMGGGITEEEYVNAILGGCRQQGVIGCTG
HHHHCCCCCEEEEECCCCCCHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCEEECC
DGVPPFIIDAGMDGIAAVEGHGIPFIKPWDGEELDQKLDRALASACPAVGMDIDAAGLVT
CCCCCEEEECCCCCEEEECCCCCCEECCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
LRKMGRPVSPKTPAQLKAVVDKVHAAGRTFILKGIMTVVDAQLAVEVGADAIVVSNHGGR
HHHCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCE
VLDHTPGAAEVLPEIADAVKGRITVLADGGVRDGFDVIKMLALGADAVLIGRPFSIAAVG
EEECCCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCEEEECCCEEEEEEC
GQAEGVAAYLEALRGQLVQAMVLTGCRSVQEAGRHILRGI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA