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The map label for this gene is uxuR [H]

Identifier: 78355796

GI number: 78355796

Start: 775784

End: 776494

Strand: Direct

Name: uxuR [H]

Synonym: Dde_0749

Alternate gene names: 78355796

Gene position: 775784-776494 (Clockwise)

Preceding gene: 78355795

Following gene: 78355797

Centisome position: 20.8

GC content: 60.76

Gene sequence:

>711_bases
ATGTCCAGAAATTCGGTCCGTTTTGTTCCGGAAGGAACCACAAAACAGTGCGTGCGTAACGAGATAGCCAACAGGCTGCG
CGAGCTTATAGCCTGCGGCGAGCTGCGGCGGGGCGACAAGCTGCCCGCCGAACGGCATCTGGCAGAGGTGCTCGGGGTTT
CGCGCCATTCCGTGCGCGAGGCAATCCGCTCGCTGGAACAGCAGGGAGTGCTGGCCAGCCGCCGCGGCGACGGCACCTAT
GTTCTTGATGACCGGCAGGAACTGCTGTACGGCCCGCTGGGCATGGCAGTGGAGCAGCGCAACATTCAGGAGGTTCTTGA
GTTCCGCAAGCTGCTTGAACCGCAGATAGCCAGTCTGGCGGCACGTAATATTTCGGGCACCGATCTTGCTCTGCTGCGGG
AAAAACTCAACGAGCAGAAAGCCGTCATTGCTCAGGGCGGTTCCGGATCGGCGCTGGACGCCGAATTTCACCTGCTTATC
GCCAAAGCCACCGGCAACCGCGTGCTGTATGAGGTGCTGGTGCGCATCCACGACATTGTCAGCGAAAGCCGCGATTTCAC
CCTGCAGACCGAAGAACGCCGCGACTGGGCGGTGATGACGCACGAGCGGGTGCTGGCGGCACTGGCGCGCCGGGACCCCG
AGGCGGCCTTTCAGGAAATGCATTCCCATATCGACTACGTGGAAAAAATTGCTCTGGAGTGGATTGACTGA

Upstream 100 bases:

>100_bases
TACCGCCTCGTCGCAGGGGATTTCATTTGTCACCGGGGGCGTGGTGCTGGAAGGGCGCCAGTAGCGTACCGGTTGCCGGT
ACGGGGCGGAGAAGACACAC

Downstream 100 bases:

>100_bases
TGCTCCGCTGAGGTTTTCGCGGCGTCGTTCTCTTGCCCGCAGCCGGCGTCTACGGTATCAATTTGGGCGATCAAACAAAT
ACGGCACCACCGGAAAGCGT

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MSRNSVRFVPEGTTKQCVRNEIANRLRELIACGELRRGDKLPAERHLAEVLGVSRHSVREAIRSLEQQGVLASRRGDGTY
VLDDRQELLYGPLGMAVEQRNIQEVLEFRKLLEPQIASLAARNISGTDLALLREKLNEQKAVIAQGGSGSALDAEFHLLI
AKATGNRVLYEVLVRIHDIVSESRDFTLQTEERRDWAVMTHERVLAALARRDPEAAFQEMHSHIDYVEKIALEWID

Sequences:

>Translated_236_residues
MSRNSVRFVPEGTTKQCVRNEIANRLRELIACGELRRGDKLPAERHLAEVLGVSRHSVREAIRSLEQQGVLASRRGDGTY
VLDDRQELLYGPLGMAVEQRNIQEVLEFRKLLEPQIASLAARNISGTDLALLREKLNEQKAVIAQGGSGSALDAEFHLLI
AKATGNRVLYEVLVRIHDIVSESRDFTLQTEERRDWAVMTHERVLAALARRDPEAAFQEMHSHIDYVEKIALEWID
>Mature_235_residues
SRNSVRFVPEGTTKQCVRNEIANRLRELIACGELRRGDKLPAERHLAEVLGVSRHSVREAIRSLEQQGVLASRRGDGTYV
LDDRQELLYGPLGMAVEQRNIQEVLEFRKLLEPQIASLAARNISGTDLALLREKLNEQKAVIAQGGSGSALDAEFHLLIA
KATGNRVLYEVLVRIHDIVSESRDFTLQTEERRDWAVMTHERVLAALARRDPEAAFQEMHSHIDYVEKIALEWID

Specific function: Repressor for the uxuRBA operon [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790780, Length=232, Percent_Identity=33.6206896551724, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI87082208, Length=221, Percent_Identity=32.1266968325792, Blast_Score=84, Evalue=6e-18,
Organism=Escherichia coli, GI1790032, Length=230, Percent_Identity=34.3478260869565, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1786303, Length=224, Percent_Identity=30.3571428571429, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786950, Length=65, Percent_Identity=52.3076923076923, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789353, Length=226, Percent_Identity=27.4336283185841, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1789621, Length=209, Percent_Identity=24.8803827751196, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 26714; Mature: 26583

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRNSVRFVPEGTTKQCVRNEIANRLRELIACGELRRGDKLPAERHLAEVLGVSRHSVRE
CCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHH
AIRSLEQQGVLASRRGDGTYVLDDRQELLYGPLGMAVEQRNIQEVLEFRKLLEPQIASLA
HHHHHHHCCCHHCCCCCCCEEECCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARNISGTDLALLREKLNEQKAVIAQGGSGSALDAEFHLLIAKATGNRVLYEVLVRIHDIV
HCCCCCHHHHHHHHHHCHHHEEEEECCCCCEECCEEEEEEEECCCCHHHHHHHHHHHHHH
SESRDFTLQTEERRDWAVMTHERVLAALARRDPEAAFQEMHSHIDYVEKIALEWID
HCCCCCEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SRNSVRFVPEGTTKQCVRNEIANRLRELIACGELRRGDKLPAERHLAEVLGVSRHSVRE
CCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHH
AIRSLEQQGVLASRRGDGTYVLDDRQELLYGPLGMAVEQRNIQEVLEFRKLLEPQIASLA
HHHHHHHCCCHHCCCCCCCEEECCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARNISGTDLALLREKLNEQKAVIAQGGSGSALDAEFHLLIAKATGNRVLYEVLVRIHDIV
HCCCCCHHHHHHHHHHCHHHEEEEECCCCCEECCEEEEEEEECCCCHHHHHHHHHHHHHH
SESRDFTLQTEERRDWAVMTHERVLAALARRDPEAAFQEMHSHIDYVEKIALEWID
HCCCCCEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]