Click here to switch to the map view.

The map label for this gene is apbE [H]

Identifier: 78355634

GI number: 78355634

Start: 610419

End: 611447

Strand: Direct

Name: apbE [H]

Synonym: Dde_0587

Alternate gene names: 78355634

Gene position: 610419-611447 (Clockwise)

Preceding gene: 78355633

Following gene: 78355636

Centisome position: 16.36

GC content: 59.38

Gene sequence:

>1029_bases
ATGGAAAAAAATACCGCATCCAGAAGACAGTTTATCCAGACATGCGGTCTGCTGGGGCTTTCCGTGGCGGCAGGGGCAGC
TTTGCCCGCTGTGGCCGGCGCCGCACGCATAGGCGGTGAGCACACCGTAACCCAGACGCGTCTGCAGATGGGCACCCTTG
TGACGCTGACAGCCGTTCATACCTCGCGCCTGCAGGCCGAGGAGGCTCTGGGGCGTGCTTTTGAAGAAATAGACAGGCTT
GCCGCCGTGTTCAGCCGGTACGACAGCACCACCCCCGTGTATGTGCTTAACCGTGACGGAAGGGTCTCAGGCATCGGGCC
TGAACTTAAGGAAGTGATGGACCGCGCGCTGCGTTTCGGCAGCCTGACGGATAATGCGTTCAACATTACGGTGAAGCCTG
TGGTCGACCTGTTCAGCAGCCGGCAGAACCTTGCCGGCAGCGTGCAGCTTTCTCAGGAAGACGTGTCGCATGCGCTTAGT
CTTGTCGATGCGCGTGGTGTGCAGCTGGGGCGCGACAGCATCCGGCTGCAGCGCGAAGGAATGGGCGTGACGCTGGACGG
CATTGCCAAAGGCTACATTGTAGACAAAGCTTCTTCCGTGCTTAGCGCCTGCGGCGTGCGCAATCATATGATCAACGCCG
GCGGCGATATACGCACCAGCGGAGAAAAAGCCGGCGGCAAACCGTGGGTTATCGCCATTCAGGACCCTGATAAAAAGCGG
AACTACCCCGCGACTATTGCCCTGCGTGATGGTGCCATTGCCACTTCCGGAGGTTATGAGGTCTTTTACGACCGCAAACG
CATGTACAGCCATCTGGTAAGCCCCGCCACCGGCAGCAGCCCGCACAGCGTGCTCAGTGTGTCGGTGACGGCTCCCACCG
TGATGGAGGCAGATACACTGGCTACTGCGGTGTATGTCATGCAGGCCCGCAGCGGTCTGCAGTTCATGGACAGCCTTACG
GGACGCGAATGTCTTATTCTGGGACGTAACGGGGCTGCCTATACATCGCGCAACTGGGCAAAAGCATAA

Upstream 100 bases:

>100_bases
GAAAGCGCAGGACGCGGCTCAGGATGAGGCTTCCGCCTGAGGGCGGCGGCAGGTTTACAACCGCGCCTGAAAAAGCGCGT
GTGATACTTGGAGTCATTCC

Downstream 100 bases:

>100_bases
AACTGCTGCCCGGGAGCATTAAAGTCCGTTCTGTCCGGCCGCTTTGCGGCCGGACTTTTTTTGTTCCGGTGCCGGTGGCG
GCTGCTGCCGCGGGATGGAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MEKNTASRRQFIQTCGLLGLSVAAGAALPAVAGAARIGGEHTVTQTRLQMGTLVTLTAVHTSRLQAEEALGRAFEEIDRL
AAVFSRYDSTTPVYVLNRDGRVSGIGPELKEVMDRALRFGSLTDNAFNITVKPVVDLFSSRQNLAGSVQLSQEDVSHALS
LVDARGVQLGRDSIRLQREGMGVTLDGIAKGYIVDKASSVLSACGVRNHMINAGGDIRTSGEKAGGKPWVIAIQDPDKKR
NYPATIALRDGAIATSGGYEVFYDRKRMYSHLVSPATGSSPHSVLSVSVTAPTVMEADTLATAVYVMQARSGLQFMDSLT
GRECLILGRNGAAYTSRNWAKA

Sequences:

>Translated_342_residues
MEKNTASRRQFIQTCGLLGLSVAAGAALPAVAGAARIGGEHTVTQTRLQMGTLVTLTAVHTSRLQAEEALGRAFEEIDRL
AAVFSRYDSTTPVYVLNRDGRVSGIGPELKEVMDRALRFGSLTDNAFNITVKPVVDLFSSRQNLAGSVQLSQEDVSHALS
LVDARGVQLGRDSIRLQREGMGVTLDGIAKGYIVDKASSVLSACGVRNHMINAGGDIRTSGEKAGGKPWVIAIQDPDKKR
NYPATIALRDGAIATSGGYEVFYDRKRMYSHLVSPATGSSPHSVLSVSVTAPTVMEADTLATAVYVMQARSGLQFMDSLT
GRECLILGRNGAAYTSRNWAKA
>Mature_342_residues
MEKNTASRRQFIQTCGLLGLSVAAGAALPAVAGAARIGGEHTVTQTRLQMGTLVTLTAVHTSRLQAEEALGRAFEEIDRL
AAVFSRYDSTTPVYVLNRDGRVSGIGPELKEVMDRALRFGSLTDNAFNITVKPVVDLFSSRQNLAGSVQLSQEDVSHALS
LVDARGVQLGRDSIRLQREGMGVTLDGIAKGYIVDKASSVLSACGVRNHMINAGGDIRTSGEKAGGKPWVIAIQDPDKKR
NYPATIALRDGAIATSGGYEVFYDRKRMYSHLVSPATGSSPHSVLSVSVTAPTVMEADTLATAVYVMQARSGLQFMDSLT
GRECLILGRNGAAYTSRNWAKA

Specific function: Involved in the conversion of aminoimidazole ribotide (AIR), a purine intermediate, to the 4-amino-5-hydroxymethyl-2- methyl pyrimidine (HMP) moiety of thiamine [H]

COG id: COG1477

COG function: function code H; Membrane-associated lipoprotein involved in thiamine biosynthesis

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ApbE family [H]

Homologues:

Organism=Escherichia coli, GI1788543, Length=216, Percent_Identity=31.4814814814815, Blast_Score=94, Evalue=9e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003374 [H]

Pfam domain/function: PF02424 ApbE [H]

EC number: NA

Molecular weight: Translated: 36491; Mature: 36491

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKNTASRRQFIQTCGLLGLSVAAGAALPAVAGAARIGGEHTVTQTRLQMGTLVTLTAVH
CCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCHHHHHHHHHCCEEEEEEHH
TSRLQAEEALGRAFEEIDRLAAVFSRYDSTTPVYVLNRDGRVSGIGPELKEVMDRALRFG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCC
SLTDNAFNITVKPVVDLFSSRQNLAGSVQLSQEDVSHALSLVDARGVQLGRDSIRLQREG
CCCCCEEEEEHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHCCCCCCCHHHEEECCC
MGVTLDGIAKGYIVDKASSVLSACGVRNHMINAGGDIRTSGEKAGGKPWVIAIQDPDKKR
CCEEHHCCCCCEEEHHHHHHHHHHHHHHHEECCCCCEECCCCCCCCCEEEEEEECCCCCC
NYPATIALRDGAIATSGGYEVFYDRKRMYSHLVSPATGSSPHSVLSVSVTAPTVMEADTL
CCCEEEEEECCCEEECCCCCEEEHHHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHH
ATAVYVMQARSGLQFMDSLTGRECLILGRNGAAYTSRNWAKA
HHHHHHHHHHCCHHHHHHCCCCEEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure
MEKNTASRRQFIQTCGLLGLSVAAGAALPAVAGAARIGGEHTVTQTRLQMGTLVTLTAVH
CCCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCCCHHHHHHHHHCCEEEEEEHH
TSRLQAEEALGRAFEEIDRLAAVFSRYDSTTPVYVLNRDGRVSGIGPELKEVMDRALRFG
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHCC
SLTDNAFNITVKPVVDLFSSRQNLAGSVQLSQEDVSHALSLVDARGVQLGRDSIRLQREG
CCCCCEEEEEHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHCCCCCCCHHHEEECCC
MGVTLDGIAKGYIVDKASSVLSACGVRNHMINAGGDIRTSGEKAGGKPWVIAIQDPDKKR
CCEEHHCCCCCEEEHHHHHHHHHHHHHHHEECCCCCEECCCCCCCCCEEEEEEECCCCCC
NYPATIALRDGAIATSGGYEVFYDRKRMYSHLVSPATGSSPHSVLSVSVTAPTVMEADTL
CCCEEEEEECCCEEECCCCCEEEHHHHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHH
ATAVYVMQARSGLQFMDSLTGRECLILGRNGAAYTSRNWAKA
HHHHHHHHHHCCHHHHHHCCCCEEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]