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The map label for this gene is yciR [C]

Identifier: 78355597

GI number: 78355597

Start: 569325

End: 571112

Strand: Direct

Name: yciR [C]

Synonym: Dde_0550

Alternate gene names: 78355597

Gene position: 569325-571112 (Clockwise)

Preceding gene: 78355594

Following gene: 78355598

Centisome position: 15.26

GC content: 61.07

Gene sequence:

>1788_bases
ATGGGCCGCACCGCAGATGAGCACTCACAGAAAACCGGCAGGTCCGGTGCTGCGCAGGGCTGTGCCCTTGCCGCTGCCCT
GTGGGAAAAAGAACAGCTTTTCAGAGTGCTTCTGGAATACAGTGCCGACTGTGAAATCTGGATTGATGCCTGCGGCGTGG
TGCGTTTTGTCTCGCCGTCATTTGCAAGCATCACCGGATATACCCCTGAATGCCTGTACAGAAATCCGGACTACCTTGCA
GCCATAATGGTGCAGAGCGATCTGCCCGCATTCCGCGCGCAGGAGCGGATTCTGGCGGAACGCGGCGGCTCTTTTGACGT
GGAGGTGCGCATACGCACGGCTTCCGGCAGGGAATGCTGGGTGCTGTGCATATGCCGGAGCATCACCGATGATGAGGGAC
GCCCGCAGGGCCGGAGACTTACCTGCCGTGATGTGACGCGCCGCCGCCTGCTTGCCATGCAGCTGCAGCATCAGGCCGGT
CACGACCCGCTGACAGGACTGCCCAACCGGTCTCTTTTTCTTGAAAAACTTGATGCGCGTGTGAATGGTGGCCGCGCAGC
GCGTGACGGCGGCGCATCTGTTGTGATGATAGATGTGGACCGCTTCAAGCAGATAAACGATGTGCTGGGTCACGAGGCGG
GAGACGGCGTGCTGCGCGTGGTGGCCGACAGGCTGCGGGGTATTCTGGGCGGCAATGACGCTCTGTGCCGTCTGGGCGGT
GATGAATTCTGCCTGCTGCTGGCCGGCGGCGGCCGTGCCGAAGAAGTGCTGGCACGGGTACAGCAGATACAGCAGCGGCT
CATGGACTCTGTTGACACGGGGGGCAGGCGGCTGCATCTGACGGTAAGTGTGGGCGTGGCCACCCACCGGCCGGGGCAGA
ACGCGCCGGAAGACATGATGCGCAACGGCGGCATTGCCCTGCAGCATGCCAAACGTGCGGGCGGCGGCGGACTGGAGGTG
TTCAGCGACTGGATGCTGGAAAGTGCGCTCAACCATGCCCGTCTGGAAATGGAACTGCACCATGCGCTGAAAGACAACGC
CTTTCATCTTGAGTTCCAGCCTCTTGTCGATCTGCATTCTGGGCGTCCCGTACGGGTGGAGGCTCTGGCCCGCTGGGATC
ATCCTCAGCGTGGGGCCGTTTCGCCCGCTGATTTCATTCCCGTTCTGGAAGAAACCGGTCAGATTCTGCGTCTGGGCAGC
TGGGTGCTGGAAAACGCCTGCATGGCTGCCGCACGCTGGCAGCGCAGGCATCCTGAGCTGCGGTCCGTCGGCGTCAGTGT
GAATCTTTCGGCCCGGCAGCTTGCACAGCCTGCGCTGGTGGATCAGGTGGCGGCGGTGCTTTCCCGCTCCGGACTGGAAC
CGGCCAGCCTGAAGCTGGAGGTGACGGAAACCATGCTCATGGACAATCCGGAACTGTCCAATCTGGTGCTTCGCAGGCTG
AAGGATCTGGGCGTTTTTCTGGCCATCGACGATTTCGGCACAGGGTATTCTTCACTGGCCTATCTGCAGAGTTTTCCCAT
TGATACGCTGAAGATCGACAAGTCTTTCGTCATGGGCATGACCAGCGACCCCGGCAAATTCAACATTGTGAAAGCGGTTA
CCGCGTTGGCGCATAGTCTGGGGCTGGATGTGGTGGCCGAAGGAGTGGAGGAACAGGAACAGCGCATCATGCTGCATGCC
GTGGGCTGCGAGTACGCGCAAGGGTTTCTGTTTGCCCGTCCTGTGCCGGAAAAAGACCTTGCCGCGCAGCTCGGCAGCCT
GCTGCGCAGTTCCTGCGATCCTGCCTGA

Upstream 100 bases:

>100_bases
CGGCTTTGCAGAACAGTACCTGATATAGTGTTTTGTGTACAGACTGTCAGCCGTGCCGGTGTGTTGTAATAATAAACCGG
TTTTGTTCCGGGGGATGTCC

Downstream 100 bases:

>100_bases
GCCTTCTTTTCCGCGTTTTTCCGCTATTCCTTCATACCCGCTTTGCGCAGGATGGTCATCAGCGGGCACCAGTCGGTAAA
TGCCGACTGCAGCAGATTTA

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 595; Mature: 594

Protein sequence:

>595_residues
MGRTADEHSQKTGRSGAAQGCALAAALWEKEQLFRVLLEYSADCEIWIDACGVVRFVSPSFASITGYTPECLYRNPDYLA
AIMVQSDLPAFRAQERILAERGGSFDVEVRIRTASGRECWVLCICRSITDDEGRPQGRRLTCRDVTRRRLLAMQLQHQAG
HDPLTGLPNRSLFLEKLDARVNGGRAARDGGASVVMIDVDRFKQINDVLGHEAGDGVLRVVADRLRGILGGNDALCRLGG
DEFCLLLAGGGRAEEVLARVQQIQQRLMDSVDTGGRRLHLTVSVGVATHRPGQNAPEDMMRNGGIALQHAKRAGGGGLEV
FSDWMLESALNHARLEMELHHALKDNAFHLEFQPLVDLHSGRPVRVEALARWDHPQRGAVSPADFIPVLEETGQILRLGS
WVLENACMAAARWQRRHPELRSVGVSVNLSARQLAQPALVDQVAAVLSRSGLEPASLKLEVTETMLMDNPELSNLVLRRL
KDLGVFLAIDDFGTGYSSLAYLQSFPIDTLKIDKSFVMGMTSDPGKFNIVKAVTALAHSLGLDVVAEGVEEQEQRIMLHA
VGCEYAQGFLFARPVPEKDLAAQLGSLLRSSCDPA

Sequences:

>Translated_595_residues
MGRTADEHSQKTGRSGAAQGCALAAALWEKEQLFRVLLEYSADCEIWIDACGVVRFVSPSFASITGYTPECLYRNPDYLA
AIMVQSDLPAFRAQERILAERGGSFDVEVRIRTASGRECWVLCICRSITDDEGRPQGRRLTCRDVTRRRLLAMQLQHQAG
HDPLTGLPNRSLFLEKLDARVNGGRAARDGGASVVMIDVDRFKQINDVLGHEAGDGVLRVVADRLRGILGGNDALCRLGG
DEFCLLLAGGGRAEEVLARVQQIQQRLMDSVDTGGRRLHLTVSVGVATHRPGQNAPEDMMRNGGIALQHAKRAGGGGLEV
FSDWMLESALNHARLEMELHHALKDNAFHLEFQPLVDLHSGRPVRVEALARWDHPQRGAVSPADFIPVLEETGQILRLGS
WVLENACMAAARWQRRHPELRSVGVSVNLSARQLAQPALVDQVAAVLSRSGLEPASLKLEVTETMLMDNPELSNLVLRRL
KDLGVFLAIDDFGTGYSSLAYLQSFPIDTLKIDKSFVMGMTSDPGKFNIVKAVTALAHSLGLDVVAEGVEEQEQRIMLHA
VGCEYAQGFLFARPVPEKDLAAQLGSLLRSSCDPA
>Mature_594_residues
GRTADEHSQKTGRSGAAQGCALAAALWEKEQLFRVLLEYSADCEIWIDACGVVRFVSPSFASITGYTPECLYRNPDYLAA
IMVQSDLPAFRAQERILAERGGSFDVEVRIRTASGRECWVLCICRSITDDEGRPQGRRLTCRDVTRRRLLAMQLQHQAGH
DPLTGLPNRSLFLEKLDARVNGGRAARDGGASVVMIDVDRFKQINDVLGHEAGDGVLRVVADRLRGILGGNDALCRLGGD
EFCLLLAGGGRAEEVLARVQQIQQRLMDSVDTGGRRLHLTVSVGVATHRPGQNAPEDMMRNGGIALQHAKRAGGGGLEVF
SDWMLESALNHARLEMELHHALKDNAFHLEFQPLVDLHSGRPVRVEALARWDHPQRGAVSPADFIPVLEETGQILRLGSW
VLENACMAAARWQRRHPELRSVGVSVNLSARQLAQPALVDQVAAVLSRSGLEPASLKLEVTETMLMDNPELSNLVLRRLK
DLGVFLAIDDFGTGYSSLAYLQSFPIDTLKIDKSFVMGMTSDPGKFNIVKAVTALAHSLGLDVVAEGVEEQEQRIMLHAV
GCEYAQGFLFARPVPEKDLAAQLGSLLRSSCDPA

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=497, Percent_Identity=33.8028169014084, Blast_Score=263, Evalue=3e-71,
Organism=Escherichia coli, GI87081921, Length=431, Percent_Identity=33.8747099767981, Blast_Score=238, Evalue=9e-64,
Organism=Escherichia coli, GI226510982, Length=417, Percent_Identity=33.3333333333333, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1790496, Length=248, Percent_Identity=34.6774193548387, Blast_Score=152, Evalue=8e-38,
Organism=Escherichia coli, GI87081743, Length=245, Percent_Identity=33.469387755102, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI87081845, Length=259, Percent_Identity=34.3629343629344, Blast_Score=135, Evalue=8e-33,
Organism=Escherichia coli, GI1786507, Length=242, Percent_Identity=31.8181818181818, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI1787055, Length=238, Percent_Identity=32.3529411764706, Blast_Score=133, Evalue=3e-32,
Organism=Escherichia coli, GI1788849, Length=286, Percent_Identity=31.8181818181818, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI1788502, Length=249, Percent_Identity=32.9317269076305, Blast_Score=126, Evalue=4e-30,
Organism=Escherichia coli, GI87081980, Length=251, Percent_Identity=34.6613545816733, Blast_Score=126, Evalue=5e-30,
Organism=Escherichia coli, GI87082096, Length=456, Percent_Identity=26.9736842105263, Blast_Score=122, Evalue=5e-29,
Organism=Escherichia coli, GI1788381, Length=318, Percent_Identity=27.3584905660377, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87081881, Length=174, Percent_Identity=35.0574712643678, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1786584, Length=168, Percent_Identity=32.1428571428571, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1787262, Length=172, Percent_Identity=28.4883720930233, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI145693134, Length=181, Percent_Identity=33.1491712707182, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1788956, Length=135, Percent_Identity=36.2962962962963, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87082007, Length=121, Percent_Identity=38.8429752066116, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1787410, Length=226, Percent_Identity=26.9911504424779, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87081977, Length=156, Percent_Identity=30.1282051282051, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87081974, Length=109, Percent_Identity=35.7798165137615, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1787816, Length=132, Percent_Identity=31.0606060606061, Blast_Score=66, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: NA

Molecular weight: Translated: 65101; Mature: 64970

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50883 EAL ; PS50887 GGDEF ; PS00284 SERPIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRTADEHSQKTGRSGAAQGCALAAALWEKEQLFRVLLEYSADCEIWIDACGVVRFVSPS
CCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHCHHHHCCCC
FASITGYTPECLYRNPDYLAAIMVQSDLPAFRAQERILAERGGSFDVEVRIRTASGRECW
CHHHCCCCHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEEEEEEECCCCCEE
VLCICRSITDDEGRPQGRRLTCRDVTRRRLLAMQLQHQAGHDPLTGLPNRSLFLEKLDAR
EEEEEHHCCCCCCCCCCCEECHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
VNGGRAARDGGASVVMIDVDRFKQINDVLGHEAGDGVLRVVADRLRGILGGNDALCRLGG
CCCCCCCCCCCCEEEEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEECC
DEFCLLLAGGGRAEEVLARVQQIQQRLMDSVDTGGRRLHLTVSVGVATHRPGQNAPEDMM
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEECCCCCCCHHHHH
RNGGIALQHAKRAGGGGLEVFSDWMLESALNHARLEMELHHALKDNAFHLEFQPLVDLHS
HCCCEEEEEHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHCCCC
GRPVRVEALARWDHPQRGAVSPADFIPVLEETGQILRLGSWVLENACMAAARWQRRHPEL
CCCEEEEHEECCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHH
RSVGVSVNLSARQLAQPALVDQVAAVLSRSGLEPASLKLEVTETMLMDNPELSNLVLRRL
HHCCEEEECCHHHHCCHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHCCCCCHHHHHHHHH
KDLGVFLAIDDFGTGYSSLAYLQSFPIDTLKIDKSFVMGMTSDPGKFNIVKAVTALAHSL
HHCCEEEEEECCCCCHHHHHHHHHCCCCEEEECHHHEECCCCCCCCCHHHHHHHHHHHHH
GLDVVAEGVEEQEQRIMLHAVGCEYAQGFLFARPVPEKDLAAQLGSLLRSSCDPA
CHHHHHHHHHHHHHEEEHHHHCCHHHCCEEEECCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GRTADEHSQKTGRSGAAQGCALAAALWEKEQLFRVLLEYSADCEIWIDACGVVRFVSPS
CCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHCHHHHCCCC
FASITGYTPECLYRNPDYLAAIMVQSDLPAFRAQERILAERGGSFDVEVRIRTASGRECW
CHHHCCCCHHHHCCCCCCEEEEEEECCCCHHHHHHHHHHHCCCCEEEEEEEEECCCCCEE
VLCICRSITDDEGRPQGRRLTCRDVTRRRLLAMQLQHQAGHDPLTGLPNRSLFLEKLDAR
EEEEEHHCCCCCCCCCCCEECHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHH
VNGGRAARDGGASVVMIDVDRFKQINDVLGHEAGDGVLRVVADRLRGILGGNDALCRLGG
CCCCCCCCCCCCEEEEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCEEEECC
DEFCLLLAGGGRAEEVLARVQQIQQRLMDSVDTGGRRLHLTVSVGVATHRPGQNAPEDMM
CCEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEECCCCCCCHHHHH
RNGGIALQHAKRAGGGGLEVFSDWMLESALNHARLEMELHHALKDNAFHLEFQPLVDLHS
HCCCEEEEEHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEHHCCCC
GRPVRVEALARWDHPQRGAVSPADFIPVLEETGQILRLGSWVLENACMAAARWQRRHPEL
CCCEEEEHEECCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCHH
RSVGVSVNLSARQLAQPALVDQVAAVLSRSGLEPASLKLEVTETMLMDNPELSNLVLRRL
HHCCEEEECCHHHHCCHHHHHHHHHHHHHCCCCCCCEEEEEEHHHHCCCCCHHHHHHHHH
KDLGVFLAIDDFGTGYSSLAYLQSFPIDTLKIDKSFVMGMTSDPGKFNIVKAVTALAHSL
HHCCEEEEEECCCCCHHHHHHHHHCCCCEEEECHHHEECCCCCCCCCHHHHHHHHHHHHH
GLDVVAEGVEEQEQRIMLHAVGCEYAQGFLFARPVPEKDLAAQLGSLLRSSCDPA
CHHHHHHHHHHHHHEEEHHHHCCHHHCCEEEECCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]