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The map label for this gene is crp [H]

Identifier: 78355510

GI number: 78355510

Start: 474056

End: 474721

Strand: Direct

Name: crp [H]

Synonym: Dde_0463

Alternate gene names: 78355510

Gene position: 474056-474721 (Clockwise)

Preceding gene: 78355509

Following gene: 78355511

Centisome position: 12.71

GC content: 55.41

Gene sequence:

>666_bases
ATGGAAGATTTCTGGAGAATACGCGCCACGGACACCGCATGGAAAGGTGTGCTGCATCTGGCGTCGCCGCGCAGGTACAG
CAGGGGCGAAGTGATTATCCGCGCCGGAGAAATGGTGGACAGCCTGTTTTATCTCGAATCCGGCGAAGTGCGCATGATCC
GTACCAGTATGGAAGGATCGGAAAAGATCCTGATGTACATCGAGGAAGGCACTCTGTTCGGCGAAACGCCGTTTTTTACC
GGTCAGCCCATCCTGAGCACGTTTGTGTGTTCGCGGCCTGCGGTTATCTGGCGCTTTTCGCGGCACAGCGTCTATGCCGA
TCTGCTGCCCAACCATCCGGAAATCGTCAGTTCGCTGCTGCACACGTTTGCGGCAAAGGTGAGCACGCTCAGCAACCAGT
CCGCCTCGCTGGGACTGCAGAATGTGGCGGAGCGGCTGTGTACGTTTTTGTATGTCACCAGCGGCGAGAGCATATCCGGT
GCCCATGGCGCCGAACTGAAACTTTCCATGAAAATGCGCGATATCGCCAACCTGCTGGGCGTGCATCGCACCACGCTGTA
CAAAGCCATCCGCGATCTTGAAAAAGAGGGTGTGCTGGAAAATTTTACCAGAGACAGTGTGCGCATTGCCGATGTGACGC
GGTTTCTGGAAATGGTGCATAAATAA

Upstream 100 bases:

>100_bases
CTGTACATCGGCGAGCTGAGAACAACCTGACAGAAACCCGCCGCGGCAGGCAGCCGCCTGCCGCGGCGGGCATGGCGCGC
AGGGCGCGCCGGAGAACATC

Downstream 100 bases:

>100_bases
CGGACCGCTGCGGCGGTTTTTTTCTCACGCAGGGGCGGGCTGCATTGCCCGGCACCTGCCGTGCGGAACATGACGGCAAG
GAGCTGTATATGAGTTTGCA

Product: Crp/FNR family transcriptional regulator

Products: NA

Alternate protein names: cAMP receptor protein; cAMP regulatory protein [H]

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MEDFWRIRATDTAWKGVLHLASPRRYSRGEVIIRAGEMVDSLFYLESGEVRMIRTSMEGSEKILMYIEEGTLFGETPFFT
GQPILSTFVCSRPAVIWRFSRHSVYADLLPNHPEIVSSLLHTFAAKVSTLSNQSASLGLQNVAERLCTFLYVTSGESISG
AHGAELKLSMKMRDIANLLGVHRTTLYKAIRDLEKEGVLENFTRDSVRIADVTRFLEMVHK

Sequences:

>Translated_221_residues
MEDFWRIRATDTAWKGVLHLASPRRYSRGEVIIRAGEMVDSLFYLESGEVRMIRTSMEGSEKILMYIEEGTLFGETPFFT
GQPILSTFVCSRPAVIWRFSRHSVYADLLPNHPEIVSSLLHTFAAKVSTLSNQSASLGLQNVAERLCTFLYVTSGESISG
AHGAELKLSMKMRDIANLLGVHRTTLYKAIRDLEKEGVLENFTRDSVRIADVTRFLEMVHK
>Mature_221_residues
MEDFWRIRATDTAWKGVLHLASPRRYSRGEVIIRAGEMVDSLFYLESGEVRMIRTSMEGSEKILMYIEEGTLFGETPFFT
GQPILSTFVCSRPAVIWRFSRHSVYADLLPNHPEIVSSLLHTFAAKVSTLSNQSASLGLQNVAERLCTFLYVTSGESISG
AHGAELKLSMKMRDIANLLGVHRTTLYKAIRDLEKEGVLENFTRDSVRIADVTRFLEMVHK

Specific function: This protein complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of one or more genes involved in the induction of competence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR018488
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 24993; Mature: 24993

Theoretical pI: Translated: 7.70; Mature: 7.70

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDFWRIRATDTAWKGVLHLASPRRYSRGEVIIRAGEMVDSLFYLESGEVRMIRTSMEGS
CCCCEEEEECCHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHCCCCCEEEEEECCCCC
EKILMYIEEGTLFGETPFFTGQPILSTFVCSRPAVIWRFSRHSVYADLLPNHPEIVSSLL
CEEEEEEECCEEECCCCCCCCCHHHHHHHHCCCCEEEEECCCCEEEHHCCCCHHHHHHHH
HTFAAKVSTLSNQSASLGLQNVAERLCTFLYVTSGESISGAHGAELKLSMKMRDIANLLG
HHHHHHHHHHCCCHHHCCHHHHHHHHHHHEEEECCCCCCCCCCCEEEEEHHHHHHHHHHH
VHRTTLYKAIRDLEKEGVLENFTRDSVRIADVTRFLEMVHK
HHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MEDFWRIRATDTAWKGVLHLASPRRYSRGEVIIRAGEMVDSLFYLESGEVRMIRTSMEGS
CCCCEEEEECCHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHCCCCCEEEEEECCCCC
EKILMYIEEGTLFGETPFFTGQPILSTFVCSRPAVIWRFSRHSVYADLLPNHPEIVSSLL
CEEEEEEECCEEECCCCCCCCCHHHHHHHHCCCCEEEEECCCCEEEHHCCCCHHHHHHHH
HTFAAKVSTLSNQSASLGLQNVAERLCTFLYVTSGESISGAHGAELKLSMKMRDIANLLG
HHHHHHHHHHCCCHHHCCHHHHHHHHHHHEEEECCCCCCCCCCCEEEEEHHHHHHHHHHH
VHRTTLYKAIRDLEKEGVLENFTRDSVRIADVTRFLEMVHK
HHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1542653; 7542800 [H]