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The map label for this gene is corA [H]

Identifier: 78355483

GI number: 78355483

Start: 442430

End: 443494

Strand: Direct

Name: corA [H]

Synonym: Dde_0436

Alternate gene names: 78355483

Gene position: 442430-443494 (Clockwise)

Preceding gene: 78355482

Following gene: 78355485

Centisome position: 11.86

GC content: 57.37

Gene sequence:

>1065_bases
ATGGCCCGTTTTCTGAAAAAGATGGACACAAGGGCGGGGCGTCCGCCGGGTGCTCTGGTTTTTGTAGGCAGACAGAAAAT
AGATACGCCGCGTCTGCGTGTCATCGAATACGATGCGGACATGGCACGCGACGATTTTGTGCAGCACCCCGGTCAGCTTG
CCGGCCGTACGCGGCCCGATACCGTGCTGTGGTGCAACGTGGACGGCGTGCACGATGCCGGACTGATGGAAACGCTGGGC
GGGCTGTTCGGCATACCGGCGCTGGTGCTTGAAGACATCATGAACACAGGTCAGCGCCCCAAGCTTGAAGAGTTTCCCGG
CATTGTCTTTGTTTCCATCAAAATGCCTTCACTCAGTCAGGACCGTTCGGCAGTGACGACAGACCAGTTGAGTGCCGTGC
TCAGCGACGGCTGTCTGCTTACTTTTCAGGAACGTCCGGGAATGGTTTTTGAGCCGGTGCGCGAGCGGTTGAAAGGGCAG
ACAGGAAGACTGCGGCGGTACGGGCCGGATTATCTGCTGTACGCGCTGCTGGATTGCGTGTTTGAGGGGTATCTGAAAAC
CATTGAGGCACTGGGCGAGCGCATAGAAGAGCTGGACGACGAAATTTTTGAAGACCCCACGCCTGAACTGCTGCAGGAGA
TAACGCATTATCGCCGCGAGATGGCCTACATACGCAAGGCGGTGCGCCCCGCGAGGGAAATCGCGTTGCGCATGGCGCGG
GTGGAAAACGGCCTTGTGGGCGAGGGCATTCAGCCTTTTCTGCGCGACCTTGCCGATATGGCCGAGATGACCGCCGATGC
CGTGGAGGTGTACCGCGAACTGCTGAACGACCATCAGAACAGTTATAACATGGCGGTGGGCAACAGACTGAACGACATCA
TGAAGTTTCTGACCATTTTTTCCACGGTATTCATTCCGCTGTCGTTTCTTGCCGGTGTGTACGGAATGAACTTTGACGTG
ATGCCCGAACTGCACGTGGAGTATGCCTATTTTGTGCTGCTGGGCGTTATGGTGGCTGTCGCGGGGGGCATGCTGGTGTA
TTTCCGCTGGCGCCGCTGGCTGTGA

Upstream 100 bases:

>100_bases
CCGCGCGGACTGTTTTTTTCTGCATCGTTGTGTATGCTGAAGGGCACAGGCGCAGGCACACCCGCACGGTGAACACCGGC
GGCCCTGCCACGGAGGAATC

Downstream 100 bases:

>100_bases
CACTGCACGCCGCAGCATGCCGCCGCGGTGCATGACAGTGGCAGGGACAGCACGGACGCAGTCTGCCGGAACCGCTCCGG
CAGGCAGACTGCCGCCTGAA

Product: magnesium and cobalt transport protein CorA

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MARFLKKMDTRAGRPPGALVFVGRQKIDTPRLRVIEYDADMARDDFVQHPGQLAGRTRPDTVLWCNVDGVHDAGLMETLG
GLFGIPALVLEDIMNTGQRPKLEEFPGIVFVSIKMPSLSQDRSAVTTDQLSAVLSDGCLLTFQERPGMVFEPVRERLKGQ
TGRLRRYGPDYLLYALLDCVFEGYLKTIEALGERIEELDDEIFEDPTPELLQEITHYRREMAYIRKAVRPAREIALRMAR
VENGLVGEGIQPFLRDLADMAEMTADAVEVYRELLNDHQNSYNMAVGNRLNDIMKFLTIFSTVFIPLSFLAGVYGMNFDV
MPELHVEYAYFVLLGVMVAVAGGMLVYFRWRRWL

Sequences:

>Translated_354_residues
MARFLKKMDTRAGRPPGALVFVGRQKIDTPRLRVIEYDADMARDDFVQHPGQLAGRTRPDTVLWCNVDGVHDAGLMETLG
GLFGIPALVLEDIMNTGQRPKLEEFPGIVFVSIKMPSLSQDRSAVTTDQLSAVLSDGCLLTFQERPGMVFEPVRERLKGQ
TGRLRRYGPDYLLYALLDCVFEGYLKTIEALGERIEELDDEIFEDPTPELLQEITHYRREMAYIRKAVRPAREIALRMAR
VENGLVGEGIQPFLRDLADMAEMTADAVEVYRELLNDHQNSYNMAVGNRLNDIMKFLTIFSTVFIPLSFLAGVYGMNFDV
MPELHVEYAYFVLLGVMVAVAGGMLVYFRWRRWL
>Mature_353_residues
ARFLKKMDTRAGRPPGALVFVGRQKIDTPRLRVIEYDADMARDDFVQHPGQLAGRTRPDTVLWCNVDGVHDAGLMETLGG
LFGIPALVLEDIMNTGQRPKLEEFPGIVFVSIKMPSLSQDRSAVTTDQLSAVLSDGCLLTFQERPGMVFEPVRERLKGQT
GRLRRYGPDYLLYALLDCVFEGYLKTIEALGERIEELDDEIFEDPTPELLQEITHYRREMAYIRKAVRPAREIALRMARV
ENGLVGEGIQPFLRDLADMAEMTADAVEVYRELLNDHQNSYNMAVGNRLNDIMKFLTIFSTVFIPLSFLAGVYGMNFDVM
PELHVEYAYFVLLGVMVAVAGGMLVYFRWRRWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 40256; Mature: 40125

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARFLKKMDTRAGRPPGALVFVGRQKIDTPRLRVIEYDADMARDDFVQHPGQLAGRTRPD
CHHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEEECCCHHHHHHHHHCCHHHCCCCCCC
TVLWCNVDGVHDAGLMETLGGLFGIPALVLEDIMNTGQRPKLEEFPGIVFVSIKMPSLSQ
EEEEECCCCCCCCHHHHHHHHHHCHHHHHHHHHHCCCCCCCHHHCCCEEEEEEECCCCCC
DRSAVTTDQLSAVLSDGCLLTFQERPGMVFEPVRERLKGQTGRLRRYGPDYLLYALLDCV
CCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHH
FEGYLKTIEALGERIEELDDEIFEDPTPELLQEITHYRREMAYIRKAVRPAREIALRMAR
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VENGLVGEGIQPFLRDLADMAEMTADAVEVYRELLNDHQNSYNMAVGNRLNDIMKFLTIF
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
STVFIPLSFLAGVYGMNFDVMPELHVEYAYFVLLGVMVAVAGGMLVYFRWRRWL
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
ARFLKKMDTRAGRPPGALVFVGRQKIDTPRLRVIEYDADMARDDFVQHPGQLAGRTRPD
HHHHHHHHHHCCCCCCEEEEECCCCCCCCCEEEEECCCHHHHHHHHHCCHHHCCCCCCC
TVLWCNVDGVHDAGLMETLGGLFGIPALVLEDIMNTGQRPKLEEFPGIVFVSIKMPSLSQ
EEEEECCCCCCCCHHHHHHHHHHCHHHHHHHHHHCCCCCCCHHHCCCEEEEEEECCCCCC
DRSAVTTDQLSAVLSDGCLLTFQERPGMVFEPVRERLKGQTGRLRRYGPDYLLYALLDCV
CCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHH
FEGYLKTIEALGERIEELDDEIFEDPTPELLQEITHYRREMAYIRKAVRPAREIALRMAR
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VENGLVGEGIQPFLRDLADMAEMTADAVEVYRELLNDHQNSYNMAVGNRLNDIMKFLTIF
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
STVFIPLSFLAGVYGMNFDVMPELHVEYAYFVLLGVMVAVAGGMLVYFRWRRWL
HHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]