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The map label for this gene is flhA

Identifier: 78355427

GI number: 78355427

Start: 375064

End: 377175

Strand: Direct

Name: flhA

Synonym: Dde_0380

Alternate gene names: 78355427

Gene position: 375064-377175 (Clockwise)

Preceding gene: 78355426

Following gene: 78355428

Centisome position: 10.05

GC content: 59.33

Gene sequence:

>2112_bases
ATGGCGGATGTAGGAACAGCACCCAGAATAGATTACGAGCGCTTCTCCAAGCACGGCGATGTCCTGCTCGCCGGCGGCGT
GGTGGTGATTCTGTTCGTCATGCTCATTCCCATGCCCACCATTGTCATGGACATCATGCTGTCGCTCAGCATTTCGCTGG
CGCTGCTGGTGCTTGTGACTTCCATGTTCATGCTTTCCCCGCTTGAATTTTCCATTTTTCCTTCGCTTCTGCTGGTTACC
ACGCTGCTGCGTCTTGCTCTTAACGTGGCAAGTACCCGTCTTATTCTGCTGCACGGTGACGAAGGCACAGATGCGGCCGG
TTCCGTTATCCAGTCCTTCGGCGAATTTGTTGTCGGCGGCAGTTATATCATCGGTATCGTGATTTTTCTTATTCTGTTCA
TTCTGAACAAAATGGTTATCACCAGCGGTACCACGCGTATCGCGGAAGTGGCGGCACGTTTTACCCTTGATGCCATGCCC
GGCAAGCAGATGGCCATCGAAGCCGACCTGAACGCCGGACTCATAGACGAGACGGAAGCCACGCGGCGGCGTGAGAATAT
CCGCAAGGAGGCTGATTTCTACGGCGCCATGGACGGTGCCGGCAAGTTTGTTCAGGGCGACGTGAGCGCGGGCATGTTCA
TCACCATGGTGAACATCATCGGGGGTATTCTCATCGGCGTGCTGCAGAAGGACATGACATGGCAGGACGCCATGACCGTG
TACACGCTGCTGACCATCGGTGACGGTCTGGTCTCCACCATTCCCTCCATCATCATTTCCACCTCTGCGGGTATCATTGT
TTCGCGTGCCGCTTCCGAAGCCAAAATGGGCGAGGAATTCATAGGCCAGCTGACGTTCAACTCCCGCGCGCTCAAACTGG
TTTCCGGCGTGCTGCTTGTTTTTGCGCTGGTACCGGGCATGCCGTTCATCCCGTTTGTCATTTTTGCTTCGCTGCTGTTT
TTTATCTCCAGAGTGGTGGGCGGTGCCAGCGACGATGTGGCCGAGCGCAGCGGTGCTGCGGGCAAGGCCGGTGTCAAGGA
CGGCGCCCCCGGCGGTGCGCTGGACAGCCCGGAAGAGGTGCAGGCTCTGCTGCCGCTGGACGTGCTGGAACTGGAAGTGG
GCTACGGACTTATTCCGCTTGTGGACGAGGAACAGGACGGCAACCTGCTCTCGCGCATCCGCTCCATCCGCCGGCAGTTC
GCTCTGGATATGGGGGTTGTCATCCCCTCGCTGCACCTGCGCGACAACCTGCAGCTCAAGCCCGGTCAGTACACGCTGCT
TATCAAGGGCAACGAGGTTGCCTCGGCAGAGATTCTCATCGACCATTATCTGGCCATGGACCCGGGCGACGCGCGGCACC
GCATCAAGGGTATCGAAACGCGCGAACCGGCATTCAATCTGCCTGCGCTGTGGATTCCCGAGTCGCAGAAGGAAGAGGCC
ATGCTGGCCGGTTACACCGTGGTGGACCCCGCAACCGTCATTGCCACGCACCTGACCGAAGTGTTCCGGCGCAATCTCGG
TTCGTTCCTCGGCCGTCAGGAAGTGCAGAACCTGCTGGACAATCTTGCCAAACATTCGCCCAAGGCGGTGGAAGAACTGG
TGCCGGGCATCCTGTCGCTGGGTGTGGTGCAGAAAGTGCTGCAGAATCTGCTGCGCGAAAACGTATCCATACGCGATCTG
CTCAGCATTGTGGAAGCGCTGGCAGACTACGGCCCGGGCGTAAAGGACGCCGATACGCTGACGGAATACGTGCGCGAACG
GCTTGCGCGGACCATCGTGAAGCCCTACATGGACAGCCAGGGGCAGCTGCCCATCGTGACACTGGACCCCGGCGTGGAGA
AAACTTTGCAGGAGGCCATCCGTCATACCGACGGGGGGGCGTATCTGGCCATGGACCCCGGCAGGGCGCATCAGCTCATC
CAGCGGGTGAATGCCGCCGTGGAAGGAGCCGTGGGTACCGACGGGCAGCCTGTGCTGCTGTCGTCTCCGGTGGTGCGGCC
GCATCTGGCGCAGCTGCTCCAGAGGTTTCTGCCCACAGTTCCTGTTATTTCGCAGGCGGAAATTCCTGCTGACATACGGC
TGACCGCCGTGGCAAACGTGGTGCTTGACTGA

Upstream 100 bases:

>100_bases
CCCTGAGGAACTCTATCAGGCAGTGGCTTCGCTGCTGGCTTCACTGATGAAATTCAAGGCCCGCCCGCAGGGGCGGTAAT
CGGAACGGAGCGTCAAAACA

Downstream 100 bases:

>100_bases
TGCAGGTGAGAACATTCAAAGGCCCCAGCGCCAAAACAGTGCTGGATATGATCAAGGCGGAGATCGGCCCCGAGGCGGTC
ATTCTGTCGTCACGCGACTG

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 703; Mature: 702

Protein sequence:

>703_residues
MADVGTAPRIDYERFSKHGDVLLAGGVVVILFVMLIPMPTIVMDIMLSLSISLALLVLVTSMFMLSPLEFSIFPSLLLVT
TLLRLALNVASTRLILLHGDEGTDAAGSVIQSFGEFVVGGSYIIGIVIFLILFILNKMVITSGTTRIAEVAARFTLDAMP
GKQMAIEADLNAGLIDETEATRRRENIRKEADFYGAMDGAGKFVQGDVSAGMFITMVNIIGGILIGVLQKDMTWQDAMTV
YTLLTIGDGLVSTIPSIIISTSAGIIVSRAASEAKMGEEFIGQLTFNSRALKLVSGVLLVFALVPGMPFIPFVIFASLLF
FISRVVGGASDDVAERSGAAGKAGVKDGAPGGALDSPEEVQALLPLDVLELEVGYGLIPLVDEEQDGNLLSRIRSIRRQF
ALDMGVVIPSLHLRDNLQLKPGQYTLLIKGNEVASAEILIDHYLAMDPGDARHRIKGIETREPAFNLPALWIPESQKEEA
MLAGYTVVDPATVIATHLTEVFRRNLGSFLGRQEVQNLLDNLAKHSPKAVEELVPGILSLGVVQKVLQNLLRENVSIRDL
LSIVEALADYGPGVKDADTLTEYVRERLARTIVKPYMDSQGQLPIVTLDPGVEKTLQEAIRHTDGGAYLAMDPGRAHQLI
QRVNAAVEGAVGTDGQPVLLSSPVVRPHLAQLLQRFLPTVPVISQAEIPADIRLTAVANVVLD

Sequences:

>Translated_703_residues
MADVGTAPRIDYERFSKHGDVLLAGGVVVILFVMLIPMPTIVMDIMLSLSISLALLVLVTSMFMLSPLEFSIFPSLLLVT
TLLRLALNVASTRLILLHGDEGTDAAGSVIQSFGEFVVGGSYIIGIVIFLILFILNKMVITSGTTRIAEVAARFTLDAMP
GKQMAIEADLNAGLIDETEATRRRENIRKEADFYGAMDGAGKFVQGDVSAGMFITMVNIIGGILIGVLQKDMTWQDAMTV
YTLLTIGDGLVSTIPSIIISTSAGIIVSRAASEAKMGEEFIGQLTFNSRALKLVSGVLLVFALVPGMPFIPFVIFASLLF
FISRVVGGASDDVAERSGAAGKAGVKDGAPGGALDSPEEVQALLPLDVLELEVGYGLIPLVDEEQDGNLLSRIRSIRRQF
ALDMGVVIPSLHLRDNLQLKPGQYTLLIKGNEVASAEILIDHYLAMDPGDARHRIKGIETREPAFNLPALWIPESQKEEA
MLAGYTVVDPATVIATHLTEVFRRNLGSFLGRQEVQNLLDNLAKHSPKAVEELVPGILSLGVVQKVLQNLLRENVSIRDL
LSIVEALADYGPGVKDADTLTEYVRERLARTIVKPYMDSQGQLPIVTLDPGVEKTLQEAIRHTDGGAYLAMDPGRAHQLI
QRVNAAVEGAVGTDGQPVLLSSPVVRPHLAQLLQRFLPTVPVISQAEIPADIRLTAVANVVLD
>Mature_702_residues
ADVGTAPRIDYERFSKHGDVLLAGGVVVILFVMLIPMPTIVMDIMLSLSISLALLVLVTSMFMLSPLEFSIFPSLLLVTT
LLRLALNVASTRLILLHGDEGTDAAGSVIQSFGEFVVGGSYIIGIVIFLILFILNKMVITSGTTRIAEVAARFTLDAMPG
KQMAIEADLNAGLIDETEATRRRENIRKEADFYGAMDGAGKFVQGDVSAGMFITMVNIIGGILIGVLQKDMTWQDAMTVY
TLLTIGDGLVSTIPSIIISTSAGIIVSRAASEAKMGEEFIGQLTFNSRALKLVSGVLLVFALVPGMPFIPFVIFASLLFF
ISRVVGGASDDVAERSGAAGKAGVKDGAPGGALDSPEEVQALLPLDVLELEVGYGLIPLVDEEQDGNLLSRIRSIRRQFA
LDMGVVIPSLHLRDNLQLKPGQYTLLIKGNEVASAEILIDHYLAMDPGDARHRIKGIETREPAFNLPALWIPESQKEEAM
LAGYTVVDPATVIATHLTEVFRRNLGSFLGRQEVQNLLDNLAKHSPKAVEELVPGILSLGVVQKVLQNLLRENVSIRDLL
SIVEALADYGPGVKDADTLTEYVRERLARTIVKPYMDSQGQLPIVTLDPGVEKTLQEAIRHTDGGAYLAMDPGRAHQLIQ
RVNAAVEGAVGTDGQPVLLSSPVVRPHLAQLLQRFLPTVPVISQAEIPADIRLTAVANVVLD

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=680, Percent_Identity=45.1470588235294, Blast_Score=550, Evalue=1e-157,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 75672; Mature: 75541

Theoretical pI: Translated: 4.71; Mature: 4.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADVGTAPRIDYERFSKHGDVLLAGGVVVILFVMLIPMPTIVMDIMLSLSISLALLVLVT
CCCCCCCCCCCHHHHHCCCCEEEECHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
SMFMLSPLEFSIFPSLLLVTTLLRLALNVASTRLILLHGDEGTDAAGSVIQSFGEFVVGG
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCHHHHHHHHHHHHHHCC
SYIIGIVIFLILFILNKMVITSGTTRIAEVAARFTLDAMPGKQMAIEADLNAGLIDETEA
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHH
TRRRENIRKEADFYGAMDGAGKFVQGDVSAGMFITMVNIIGGILIGVLQKDMTWQDAMTV
HHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
YTLLTIGDGLVSTIPSIIISTSAGIIVSRAASEAKMGEEFIGQLTFNSRALKLVSGVLLV
HHHHHHCCHHHHHHHHHHHHCCCCHHEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
FALVPGMPFIPFVIFASLLFFISRVVGGASDDVAERSGAAGKAGVKDGAPGGALDSPEEV
HHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCHHHH
QALLPLDVLELEVGYGLIPLVDEEQDGNLLSRIRSIRRQFALDMGVVIPSLHLRDNLQLK
HHHCCHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEC
PGQYTLLIKGNEVASAEILIDHYLAMDPGDARHRIKGIETREPAFNLPALWIPESQKEEA
CCCEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCEEECCCCCCCCH
MLAGYTVVDPATVIATHLTEVFRRNLGSFLGRQEVQNLLDNLAKHSPKAVEELVPGILSL
HHCCCEECCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
GVVQKVLQNLLRENVSIRDLLSIVEALADYGPGVKDADTLTEYVRERLARTIVKPYMDSQ
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
GQLPIVTLDPGVEKTLQEAIRHTDGGAYLAMDPGRAHQLIQRVNAAVEGAVGTDGQPVLL
CCEEEEEECCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCEEE
SSPVVRPHLAQLLQRFLPTVPVISQAEIPADIRLTAVANVVLD
CCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEHHHHHHHHCC
>Mature Secondary Structure 
ADVGTAPRIDYERFSKHGDVLLAGGVVVILFVMLIPMPTIVMDIMLSLSISLALLVLVT
CCCCCCCCCCHHHHHCCCCEEEECHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
SMFMLSPLEFSIFPSLLLVTTLLRLALNVASTRLILLHGDEGTDAAGSVIQSFGEFVVGG
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCCHHHHHHHHHHHHHHCC
SYIIGIVIFLILFILNKMVITSGTTRIAEVAARFTLDAMPGKQMAIEADLNAGLIDETEA
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCHHH
TRRRENIRKEADFYGAMDGAGKFVQGDVSAGMFITMVNIIGGILIGVLQKDMTWQDAMTV
HHHHHHHHHHHHHHCCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
YTLLTIGDGLVSTIPSIIISTSAGIIVSRAASEAKMGEEFIGQLTFNSRALKLVSGVLLV
HHHHHHCCHHHHHHHHHHHHCCCCHHEEHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
FALVPGMPFIPFVIFASLLFFISRVVGGASDDVAERSGAAGKAGVKDGAPGGALDSPEEV
HHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCHHHH
QALLPLDVLELEVGYGLIPLVDEEQDGNLLSRIRSIRRQFALDMGVVIPSLHLRDNLQLK
HHHCCHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEC
PGQYTLLIKGNEVASAEILIDHYLAMDPGDARHRIKGIETREPAFNLPALWIPESQKEEA
CCCEEEEEECCCCCHHHHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCEEECCCCCCCCH
MLAGYTVVDPATVIATHLTEVFRRNLGSFLGRQEVQNLLDNLAKHSPKAVEELVPGILSL
HHCCCEECCHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
GVVQKVLQNLLRENVSIRDLLSIVEALADYGPGVKDADTLTEYVRERLARTIVKPYMDSQ
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
GQLPIVTLDPGVEKTLQEAIRHTDGGAYLAMDPGRAHQLIQRVNAAVEGAVGTDGQPVLL
CCEEEEEECCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCEEE
SSPVVRPHLAQLLQRFLPTVPVISQAEIPADIRLTAVANVVLD
CCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]