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The map label for this gene is zraR [H]

Identifier: 78355374

GI number: 78355374

Start: 315497

End: 315925

Strand: Direct

Name: zraR [H]

Synonym: Dde_0327

Alternate gene names: 78355374

Gene position: 315497-315925 (Clockwise)

Preceding gene: 78355373

Following gene: 78355375

Centisome position: 8.46

GC content: 52.91

Gene sequence:

>429_bases
ATGTCTGAAAAAGTGCTTATCGTCGATGACGAACAGGAATTTCTGGATGCGCTGGCAGAACGCATGCGTGCCCGCGGTAT
GGATGTGACCACTGCCACATCGCCCATCGAGGCGCTGGCTCTGGTGGCGCGCCGGTCGTTCGATGCCATCGTGCTTGATT
TTCAGATGCCCGAACTGGACGGGCTGGAAACCCTTAAACGCATGAAAGATGCCAATGACGATGTTCAGGTCATTGTGCTG
ACAGGTCATGCCACCGTGGAGCGCGGTGTTGAAGTAATGAAACACGGCGCCATGGATTTTGTGGAAAAGTCCGCCGACAT
CAACAGTCTGACGGAAAAAATCCAAGAGGCCAGCGCTAAAAAGCTGGTCATCGCGGAAGAAAAGACCCGTGAAAAGATTC
AGGCCATTCTCGAAGAGAAAGGGTGGTAA

Upstream 100 bases:

>100_bases
CGTGCCCAGAGTAGGCATGTAACTGCCTGATACAAGCCGGAGCGCGGCTTCGTGCCGTGCTCCGGCATACGGATATGATC
CTTATCGAAGGAGAACGGAT

Downstream 100 bases:

>100_bases
GCAGGACCGCCCCGGCCGACCATGCAGGTGTAAGGAGAGGAACTATGTCTGTCATCGCTGTCCACTATGGGATCTACTGC
CACGAAGACCAGTACCTGAG

Product: response regulator receiver domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 141

Protein sequence:

>142_residues
MSEKVLIVDDEQEFLDALAERMRARGMDVTTATSPIEALALVARRSFDAIVLDFQMPELDGLETLKRMKDANDDVQVIVL
TGHATVERGVEVMKHGAMDFVEKSADINSLTEKIQEASAKKLVIAEEKTREKIQAILEEKGW

Sequences:

>Translated_142_residues
MSEKVLIVDDEQEFLDALAERMRARGMDVTTATSPIEALALVARRSFDAIVLDFQMPELDGLETLKRMKDANDDVQVIVL
TGHATVERGVEVMKHGAMDFVEKSADINSLTEKIQEASAKKLVIAEEKTREKIQAILEEKGW
>Mature_141_residues
SEKVLIVDDEQEFLDALAERMRARGMDVTTATSPIEALALVARRSFDAIVLDFQMPELDGLETLKRMKDANDDVQVIVLT
GHATVERGVEVMKHGAMDFVEKSADINSLTEKIQEASAKKLVIAEEKTREKIQAILEEKGW

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=115, Percent_Identity=34.7826086956522, Blast_Score=77, Evalue=3e-16,
Organism=Escherichia coli, GI1788550, Length=114, Percent_Identity=35.0877192982456, Blast_Score=74, Evalue=5e-15,
Organism=Escherichia coli, GI1788905, Length=136, Percent_Identity=30.1470588235294, Blast_Score=63, Evalue=7e-12,
Organism=Escherichia coli, GI1790299, Length=104, Percent_Identity=30.7692307692308, Blast_Score=62, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 15873; Mature: 15742

Theoretical pI: Translated: 4.45; Mature: 4.45

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKVLIVDDEQEFLDALAERMRARGMDVTTATSPIEALALVARRSFDAIVLDFQMPELD
CCCCEEEEECHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCC
GLETLKRMKDANDDVQVIVLTGHATVERGVEVMKHGAMDFVEKSADINSLTEKIQEASAK
HHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
KLVIAEEKTREKIQAILEEKGW
EEEEECHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SEKVLIVDDEQEFLDALAERMRARGMDVTTATSPIEALALVARRSFDAIVLDFQMPELD
CCCEEEEECHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCC
GLETLKRMKDANDDVQVIVLTGHATVERGVEVMKHGAMDFVEKSADINSLTEKIQEASAK
HHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHC
KLVIAEEKTREKIQAILEEKGW
EEEEECHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]