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The map label for this gene is coaX

Identifier: 78355341

GI number: 78355341

Start: 284016

End: 284807

Strand: Direct

Name: coaX

Synonym: Dde_0294

Alternate gene names: 78355341

Gene position: 284016-284807 (Clockwise)

Preceding gene: 78355340

Following gene: 78355342

Centisome position: 7.61

GC content: 60.35

Gene sequence:

>792_bases
ATGCCCTCAGTTTTTCTTCTGTTTGATATAGGCAATACCAATGTTAAAATAGGCATTGCAGACCATGACGGCGTGGTTGC
CTCGTATGTGCTGCCCACAGACACGCATCAGACAGGCGATTCGCTCGGCCTGCGTCTGGCGGATGTGGTGCGCCATGCGG
GATTTGCCCCCGGCGACGTGACAGCCTGTGTGGCCAGTTCCGTGGTTCCCAGTTTCAATCCGCTCATGCGGCAGGCCTGC
GGGCGCTACTTTGACCGCCGGCTGCTGCTGGCGCCGGAGGACATAGCCATTCCGCTGGAAAACCGCTACGAGCGCCCGCA
GGAAGTGGGAGCGGACCGGCTGGTGGCAGCCTTTGCCGCACGGCGGCTGTGGCCTGCGCCGCGGTCCATTGTTTCGGTTG
ATTACGGCACGGCAACGACGTTTGACTGTGTGCAGGGCGAAGCGTATCTTGGGGGGCTGATATGCCCCGGAGTGCACTCC
GCGGCAGGAGCACTGGCAGCGGGCACCGCACGCCTGCCCCGCATCAGTCTTGATGTGCGCGAAGATTTGCCGGTGGTGGG
ACGCAGCACCAGCATGAGTCTCAACCACGGGTTTGTTTTCGGGTTTGCCTCCATGACCGAAGGTCTGTGTCACAGACTTT
CCGCCGTGCTTGAGGCGCCCATGCAGGTGGTGGCCACGGGAGGTTTTGCCTCTGCCATCGCCCGCGTAAGTAATTGTTTC
GATCATGTCAGGCCCGACCTTTTGCTGGAAGGCCTGAGAATTCTCTACATGGAAAGCGGAATAAAGGGCTGA

Upstream 100 bases:

>100_bases
CCGCTGCTGGCAGGCCGTATCGGGCGGGCTGCCGGGCAGGGTATGGAGACCATGAACATTTCACTCAAAGCCGTGGCTCA
GGCCCGGCGGTAGCTTGCAT

Downstream 100 bases:

>100_bases
TGCCTTTGCCGCAACCGCCCCAACAGGCGTAGCGGAGCAGTATTGACGCTCCGCCAAGCTCAAGGAGAACAGCAGTATGA
GCACCATCGTTTCCGTCTGG

Product: pantothenate kinase

Products: NA

Alternate protein names: PanK-III; Pantothenic acid kinase

Number of amino acids: Translated: 263; Mature: 262

Protein sequence:

>263_residues
MPSVFLLFDIGNTNVKIGIADHDGVVASYVLPTDTHQTGDSLGLRLADVVRHAGFAPGDVTACVASSVVPSFNPLMRQAC
GRYFDRRLLLAPEDIAIPLENRYERPQEVGADRLVAAFAARRLWPAPRSIVSVDYGTATTFDCVQGEAYLGGLICPGVHS
AAGALAAGTARLPRISLDVREDLPVVGRSTSMSLNHGFVFGFASMTEGLCHRLSAVLEAPMQVVATGGFASAIARVSNCF
DHVRPDLLLEGLRILYMESGIKG

Sequences:

>Translated_263_residues
MPSVFLLFDIGNTNVKIGIADHDGVVASYVLPTDTHQTGDSLGLRLADVVRHAGFAPGDVTACVASSVVPSFNPLMRQAC
GRYFDRRLLLAPEDIAIPLENRYERPQEVGADRLVAAFAARRLWPAPRSIVSVDYGTATTFDCVQGEAYLGGLICPGVHS
AAGALAAGTARLPRISLDVREDLPVVGRSTSMSLNHGFVFGFASMTEGLCHRLSAVLEAPMQVVATGGFASAIARVSNCF
DHVRPDLLLEGLRILYMESGIKG
>Mature_262_residues
PSVFLLFDIGNTNVKIGIADHDGVVASYVLPTDTHQTGDSLGLRLADVVRHAGFAPGDVTACVASSVVPSFNPLMRQACG
RYFDRRLLLAPEDIAIPLENRYERPQEVGADRLVAAFAARRLWPAPRSIVSVDYGTATTFDCVQGEAYLGGLICPGVHSA
AGALAAGTARLPRISLDVREDLPVVGRSTSMSLNHGFVFGFASMTEGLCHRLSAVLEAPMQVVATGGFASAIARVSNCFD
HVRPDLLLEGLRILYMESGIKG

Specific function: Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis

COG id: COG1521

COG function: function code K; Putative transcriptional regulator, homolog of Bvg accessory factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type III pantothenate kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAX_DESDG (Q316Q1)

Other databases:

- EMBL:   CP000112
- RefSeq:   YP_386790.1
- ProteinModelPortal:   Q316Q1
- SMR:   Q316Q1
- STRING:   Q316Q1
- GeneID:   3755115
- GenomeReviews:   CP000112_GR
- KEGG:   dde:Dde_0294
- NMPDR:   fig|207559.3.peg.1084
- eggNOG:   COG1521
- HOGENOM:   HBG634537
- OMA:   PAIVVDF
- ProtClustDB:   PRK13321
- BioCyc:   DDES207559:DDE_0294-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01274
- InterPro:   IPR004619
- TIGRFAMs:   TIGR00671

Pfam domain/function: PF03309 Bvg_acc_factor

EC number: =2.7.1.33

Molecular weight: Translated: 28011; Mature: 27880

Theoretical pI: Translated: 6.39; Mature: 6.39

Prosite motif: NA

Important sites: ACT_SITE 112-112 BINDING 103-103 BINDING 137-137 BINDING 190-190

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSVFLLFDIGNTNVKIGIADHDGVVASYVLPTDTHQTGDSLGLRLADVVRHAGFAPGDV
CCCEEEEEEECCCEEEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCHH
TACVASSVVPSFNPLMRQACGRYFDRRLLLAPEDIAIPLENRYERPQEVGADRLVAAFAA
HHHHHHHHCCCCCHHHHHHHHHHHHCEEEECCCCEEECHHHHCCCHHHHCHHHHHHHHHH
RRLWPAPRSIVSVDYGTATTFDCVQGEAYLGGLICPGVHSAAGALAAGTARLPRISLDVR
HHCCCCCCCEEEECCCCCCCHHHHCCCHHCCCEECCCCHHHHHHHHHCCCCCCEEEEECC
EDLPVVGRSTSMSLNHGFVFGFASMTEGLCHRLSAVLEAPMQVVATGGFASAIARVSNCF
CCCCCCCCCCCEECCCCEEEEHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHH
DHVRPDLLLEGLRILYMESGIKG
HHCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PSVFLLFDIGNTNVKIGIADHDGVVASYVLPTDTHQTGDSLGLRLADVVRHAGFAPGDV
CCEEEEEEECCCEEEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCHH
TACVASSVVPSFNPLMRQACGRYFDRRLLLAPEDIAIPLENRYERPQEVGADRLVAAFAA
HHHHHHHHCCCCCHHHHHHHHHHHHCEEEECCCCEEECHHHHCCCHHHHCHHHHHHHHHH
RRLWPAPRSIVSVDYGTATTFDCVQGEAYLGGLICPGVHSAAGALAAGTARLPRISLDVR
HHCCCCCCCEEEECCCCCCCHHHHCCCHHCCCEECCCCHHHHHHHHHCCCCCCEEEEECC
EDLPVVGRSTSMSLNHGFVFGFASMTEGLCHRLSAVLEAPMQVVATGGFASAIARVSNCF
CCCCCCCCCCCEECCCCEEEEHHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHH
DHVRPDLLLEGLRILYMESGIKG
HHCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA