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The map label for this gene is trxB [H]

Identifier: 78355257

GI number: 78355257

Start: 189360

End: 191012

Strand: Direct

Name: trxB [H]

Synonym: Dde_0210

Alternate gene names: 78355257

Gene position: 189360-191012 (Clockwise)

Preceding gene: 78355254

Following gene: 78355259

Centisome position: 5.08

GC content: 57.83

Gene sequence:

>1653_bases
ATGAGCGAAAATGATTCTGCACAGAACAGCGAAGAACGCCGGTGGCTTATACCCGAAGAAGGACGCAAGCATCTGGCCGG
TGTGTTTGCCGGACTGCCCGGTGAGGTCACTCTGGATGTCTTTACCGACGGCGATGAAAAAAATCAGTACAATGAATACA
CTGTCCGGTTTGCGCAGGAGCTTGCGGAACTGGCCGATAAAATAGACACCCGCGTGCATGCTCTGGACAGTGCCGAGGCT
CAGCGGCTGGGCGTCACGCTGGGACCGAGCACGCTGCTCAATGCCGGTACCTACGCCATACGGTTTACCGGTGCACCGCT
GGGAGAAGAAGCCAGAGGGTTCATTGAAGCCATTATGCTTGTTTCCGCCGGTAAGGCCGCTGTTTCTGAAAACGTGGGCA
GGATTCTTGAACGGCTGGAAGAAAAAAGAACCGTCCGGGTGTTTTCGTCGCCGGGGTGTCCCTACTGCCCCGGGCAGGTG
GTGAACGCGGTGAAATGCGCCATTGCCAGCCCTCAGCTGGTCAGTGCCGAGGCAGTCAATTCTGACGAATTTCCCGAGCT
TTCACGCAAGTACGGCGTCGGTTCGGTTCCGCATACCAACATCAATGACGAGTTTGACGCCGTGGGGCTGATGCCTGAAG
AGCGCTTTGCGGTTGAACTGGTAACCATGAAGGACGCTTCCGGCATGGTGCGTGAAGCCGGACAGGATGCGGGCACAGGC
GACTACCCCGTGGAAAAGGTTGATCTGGTGATTGTGGGTGCGGGGCCTGCCGGTCTGACGGCCGGTATCTATGCCGAACG
CAGCGGTTTGAAAAGCGTGGTGCTGGACAAGGCTGTTGTGGGCGGACAGGTGGCGGTGACACCCGTGGTGGAAAACTATC
CCGGCTTTAAAAATGTGGGCGGCATGAATCTGGTGGAGATGCTGGCCGCGCATACCCGTGAATATGCCCATGTGCAGGAG
CATGAAGAAATAGAGGAAATCAAGATAGGCCGTAACATAGAGGTGTACACGGCAAGAAACGTGTATCTGGCGCGTGCGCT
TGTGTTTGCCACCGGTGCCCAGTGGCGTGAACTGGGCGTGCCGGGAGAGGATACCTACTTCGGCAAGGGGGTTTCGCACT
GCGCATCGTGTGACGGTTTCATGTTCAAGGGTAAAAAAGTCATCATTGTGGGCGGCGGCAATACGGCACTGACCGATGCG
CTGCATCTGAAAAATCTGGGTGTGGATATCACCGTGGTGCACCGCCGCGACGCCTTCAGGGCGGAACAGCAGCTGCAGGA
TGCGCTGGAGCGCGAGCAGATTCCCGTGTTGTGGGACACTGTGGTGGAGGAAATACTGGGCACTGACGGTCTGGTCACCG
GTGCCAGACTGAAAAACGTCAAAAGCGGCGATGTGCACGAAGTGGCACTGGACGGGGTGTTCGTGGCCGTGGGACATGTG
CCTAATTCCGCTCTGGCTGCCGAGCTGGGGGTCACGCTTAATGAAGACGGCACCATAGCGGTGGACCGTGCCATGCGTAC
CAATATCCCCAGAGTGTACGCTGCCGGTGATGTGACCGGCGGCATACGGCAGATAGTGACAGCCGTGGGCAACGGTGCCA
CGGCGGCGCTGTCGGCATTTGAAGACCTGCAGTCTTCGCGCTGGAAGAAATAA

Upstream 100 bases:

>100_bases
AAAGGCAAGCGGCCTTGCACCGTTCTGCCGATGTGGTATGCTGAGCTGTAAATCATGCAACATATTCTTTCAGTTACGAA
TATAAGCAATGGAGGTCTCC

Downstream 100 bases:

>100_bases
GTCCGGAGAATCCCTGCGGGCGGCGGCCGGTTTACAGAAAGGCTGCCGCCCGTTTTCCATGGTGTGTCACACAGCCAGCC
GGACAGCGTTTTTTCCGGCG

Product: AhpF family protein/thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 550; Mature: 549

Protein sequence:

>550_residues
MSENDSAQNSEERRWLIPEEGRKHLAGVFAGLPGEVTLDVFTDGDEKNQYNEYTVRFAQELAELADKIDTRVHALDSAEA
QRLGVTLGPSTLLNAGTYAIRFTGAPLGEEARGFIEAIMLVSAGKAAVSENVGRILERLEEKRTVRVFSSPGCPYCPGQV
VNAVKCAIASPQLVSAEAVNSDEFPELSRKYGVGSVPHTNINDEFDAVGLMPEERFAVELVTMKDASGMVREAGQDAGTG
DYPVEKVDLVIVGAGPAGLTAGIYAERSGLKSVVLDKAVVGGQVAVTPVVENYPGFKNVGGMNLVEMLAAHTREYAHVQE
HEEIEEIKIGRNIEVYTARNVYLARALVFATGAQWRELGVPGEDTYFGKGVSHCASCDGFMFKGKKVIIVGGGNTALTDA
LHLKNLGVDITVVHRRDAFRAEQQLQDALEREQIPVLWDTVVEEILGTDGLVTGARLKNVKSGDVHEVALDGVFVAVGHV
PNSALAAELGVTLNEDGTIAVDRAMRTNIPRVYAAGDVTGGIRQIVTAVGNGATAALSAFEDLQSSRWKK

Sequences:

>Translated_550_residues
MSENDSAQNSEERRWLIPEEGRKHLAGVFAGLPGEVTLDVFTDGDEKNQYNEYTVRFAQELAELADKIDTRVHALDSAEA
QRLGVTLGPSTLLNAGTYAIRFTGAPLGEEARGFIEAIMLVSAGKAAVSENVGRILERLEEKRTVRVFSSPGCPYCPGQV
VNAVKCAIASPQLVSAEAVNSDEFPELSRKYGVGSVPHTNINDEFDAVGLMPEERFAVELVTMKDASGMVREAGQDAGTG
DYPVEKVDLVIVGAGPAGLTAGIYAERSGLKSVVLDKAVVGGQVAVTPVVENYPGFKNVGGMNLVEMLAAHTREYAHVQE
HEEIEEIKIGRNIEVYTARNVYLARALVFATGAQWRELGVPGEDTYFGKGVSHCASCDGFMFKGKKVIIVGGGNTALTDA
LHLKNLGVDITVVHRRDAFRAEQQLQDALEREQIPVLWDTVVEEILGTDGLVTGARLKNVKSGDVHEVALDGVFVAVGHV
PNSALAAELGVTLNEDGTIAVDRAMRTNIPRVYAAGDVTGGIRQIVTAVGNGATAALSAFEDLQSSRWKK
>Mature_549_residues
SENDSAQNSEERRWLIPEEGRKHLAGVFAGLPGEVTLDVFTDGDEKNQYNEYTVRFAQELAELADKIDTRVHALDSAEAQ
RLGVTLGPSTLLNAGTYAIRFTGAPLGEEARGFIEAIMLVSAGKAAVSENVGRILERLEEKRTVRVFSSPGCPYCPGQVV
NAVKCAIASPQLVSAEAVNSDEFPELSRKYGVGSVPHTNINDEFDAVGLMPEERFAVELVTMKDASGMVREAGQDAGTGD
YPVEKVDLVIVGAGPAGLTAGIYAERSGLKSVVLDKAVVGGQVAVTPVVENYPGFKNVGGMNLVEMLAAHTREYAHVQEH
EEIEEIKIGRNIEVYTARNVYLARALVFATGAQWRELGVPGEDTYFGKGVSHCASCDGFMFKGKKVIIVGGGNTALTDAL
HLKNLGVDITVVHRRDAFRAEQQLQDALEREQIPVLWDTVVEEILGTDGLVTGARLKNVKSGDVHEVALDGVFVAVGHVP
NSALAAELGVTLNEDGTIAVDRAMRTNIPRVYAAGDVTGGIRQIVTAVGNGATAALSAFEDLQSSRWKK

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=304, Percent_Identity=39.1447368421053, Blast_Score=199, Evalue=3e-52,
Organism=Escherichia coli, GI87081763, Length=499, Percent_Identity=30.060120240481, Blast_Score=184, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6320560, Length=313, Percent_Identity=31.9488817891374, Blast_Score=157, Evalue=5e-39,
Organism=Saccharomyces cerevisiae, GI6321898, Length=307, Percent_Identity=32.2475570032573, Blast_Score=149, Evalue=1e-36,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 58902; Mature: 58771

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSENDSAQNSEERRWLIPEEGRKHLAGVFAGLPGEVTLDVFTDGDEKNQYNEYTVRFAQE
CCCCCCCCCCCCCEECCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHH
LAELADKIDTRVHALDSAEAQRLGVTLGPSTLLNAGTYAIRFTGAPLGEEARGFIEAIML
HHHHHHHHHHHHHHHCCCHHHHCCEEECCHHHHCCCCEEEEEECCCCCHHHHHHHHHHHH
VSAGKAAVSENVGRILERLEEKRTVRVFSSPGCPYCPGQVVNAVKCAIASPQLVSAEAVN
HHCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCEEEHHCCC
SDEFPELSRKYGVGSVPHTNINDEFDAVGLMPEERFAVELVTMKDASGMVREAGQDAGTG
CCCCHHHHHHCCCCCCCCCCCCCCCCEECCCCCCCEEEEEEEECCCCHHHHHCCCCCCCC
DYPVEKVDLVIVGAGPAGLTAGIYAERSGLKSVVLDKAVVGGQVAVTPVVENYPGFKNVG
CCCCEEEEEEEEECCCCCCHHHHHHHHCCHHHHHHHHHHCCCEEEEEEEHHCCCCCCCCC
GMNLVEMLAAHTREYAHVQEHEEIEEIKIGRNIEVYTARNVYLARALVFATGAQWRELGV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHCCCCHHHCCC
PGEDTYFGKGVSHCASCDGFMFKGKKVIIVGGGNTALTDALHLKNLGVDITVVHRRDAFR
CCCCCCCCCCHHHHHCCCCEEECCCEEEEEECCCHHHHHHHHHHHCCEEEEEEECCHHHH
AEQQLQDALEREQIPVLWDTVVEEILGTDGLVTGARLKNVKSGDVHEVALDGVFVAVGHV
HHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEECHHHCCCCCCCCCEEECCCEEEEEECC
PNSALAAELGVTLNEDGTIAVDRAMRTNIPRVYAAGDVTGGIRQIVTAVGNGATAALSAF
CCHHHHHHHCCEECCCCCEEECHHHHCCCCEEEECCCCCHHHHHHHHHHCCCHHHHHHHH
EDLQSSRWKK
HHHHHHCCCC
>Mature Secondary Structure 
SENDSAQNSEERRWLIPEEGRKHLAGVFAGLPGEVTLDVFTDGDEKNQYNEYTVRFAQE
CCCCCCCCCCCCEECCCHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHH
LAELADKIDTRVHALDSAEAQRLGVTLGPSTLLNAGTYAIRFTGAPLGEEARGFIEAIML
HHHHHHHHHHHHHHHCCCHHHHCCEEECCHHHHCCCCEEEEEECCCCCHHHHHHHHHHHH
VSAGKAAVSENVGRILERLEEKRTVRVFSSPGCPYCPGQVVNAVKCAIASPQLVSAEAVN
HHCCHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCEEEHHCCC
SDEFPELSRKYGVGSVPHTNINDEFDAVGLMPEERFAVELVTMKDASGMVREAGQDAGTG
CCCCHHHHHHCCCCCCCCCCCCCCCCEECCCCCCCEEEEEEEECCCCHHHHHCCCCCCCC
DYPVEKVDLVIVGAGPAGLTAGIYAERSGLKSVVLDKAVVGGQVAVTPVVENYPGFKNVG
CCCCEEEEEEEEECCCCCCHHHHHHHHCCHHHHHHHHHHCCCEEEEEEEHHCCCCCCCCC
GMNLVEMLAAHTREYAHVQEHEEIEEIKIGRNIEVYTARNVYLARALVFATGAQWRELGV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHCCCCHHHCCC
PGEDTYFGKGVSHCASCDGFMFKGKKVIIVGGGNTALTDALHLKNLGVDITVVHRRDAFR
CCCCCCCCCCHHHHHCCCCEEECCCEEEEEECCCHHHHHHHHHHHCCEEEEEEECCHHHH
AEQQLQDALEREQIPVLWDTVVEEILGTDGLVTGARLKNVKSGDVHEVALDGVFVAVGHV
HHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEECHHHCCCCCCCCCEEECCCEEEEEECC
PNSALAAELGVTLNEDGTIAVDRAMRTNIPRVYAAGDVTGGIRQIVTAVGNGATAALSAF
CCHHHHHHHCCEECCCCCEEECHHHHCCCCEEEECCCCCHHHHHHHHHHCCCHHHHHHHH
EDLQSSRWKK
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA