Click here to switch to the map view.

The map label for this gene is dinB [H]

Identifier: 78222653

GI number: 78222653

Start: 1609858

End: 1611081

Strand: Direct

Name: dinB [H]

Synonym: Gmet_1441

Alternate gene names: 78222653

Gene position: 1609858-1611081 (Clockwise)

Preceding gene: 78222652

Following gene: 78222654

Centisome position: 40.27

GC content: 63.24

Gene sequence:

>1224_bases
ATGCACGTGGACATGAACGCCTTTTTCGCCAGCGTGGAGCAGCAGCACGACCCCGCGCTCAGGGGCAAGCCCATCGCCGT
CATCGGCTCCGCAGCCCGCACCGTCATCACCACTGCCTCCTACGAGGCCCGGGCCTTTGGCGTCAAAACCGGCATGACCG
TCTGGCAGGCACAACAGAAATGCCCCCAGATCATCCTCGTCACCGGAGACAACCGGAAATACACCTACACCTCCGCCCGG
ATCGTCGAGATGATGAAGCAGTTCACCCCGCTGGTGGAGGTCTTCTCCATCGACGAGGCCTTTCTCGACGTCACCGGCTC
CCTCTCCCTGTATTCCAGCGCCGAGCGGATCGCCTTTCTCCTCAAGGCCGAGATCCGGCACCACTTCGGCCTTACCTGCT
CCATCGGCATCGCCCCCAACAAGCTCCTCGCCAAGCTCGCCTCGGAGATGAAAAAGCCCGACGGCCTCACCGTCATCAAG
CCCGACGACGTTGCCCCGGTCCTCGAAACCCTGCCGATCAAGGAACTCTGCGGTATCGGCGCCAAGATGGAGTGCCAGCT
GAACCTCCTGGGGATCAGAACCTGCGGCGAGTTGGGCCGCTACCCGGTGGACCGGCTGATGCGCAAATTCGGGATAGTGG
GCGAGAAGCTCCACCTCATGGGGCAGGGGATCGACGACTCCCCGGTAGTCCCCCACGAAGAGGCCGAGGAAGTCAAATCG
GTGGGCCACTCGACGACGCTTGAGCACGACATCGAGGACCGGCGGGAGATCCTTAGGTGGCTCCTCCAACTCTCCGAGAT
GGTGGGGCGCCGGGCCCGCAGATATAACGTCTGGGGAAAGACCGTCACCCTCTCCATCCGCTACGCCGACTTCGACACCT
GGGTAGGGAGGCAGGAAACGCTCCCCCACCACATCAACCAGAGCGATGACATCTACCGGGCCGCCGTCGCCATCCTCGAT
ACTCTTGTCCTGGAGCAGCCGGTAAGGCTCCTGGGGGTAAGGCTCAGTAACCTCCGCTACGAGTCGAACCAACTGCCGCT
CTTCGAGGAGGAGCGGAAGAAGGTGCTCCTGGCCGGGGCCATGGACCAGGTGAACGACAGGTTCGGCGACTTCGCCGTCA
CCTTTGGGAGCCTCCTGGACAAGGAGCGGCGCCAGGAGAAGGGCTCCCACGTCATCTCCCCCGCCTGGCGGCCGGAGGGG
ATCAGGAATGTGGATGTGAAGTGA

Upstream 100 bases:

>100_bases
CCGACGGCACTGCCCTCTATGAGCTGATCTACAACTCCCGGGAACAACTCTGGACCCTGGAAGCGGCCGATGCGGAGGTC
GTGTGAGCGGCCGGGTCATC

Downstream 100 bases:

>100_bases
ACACCCGAACCTCAGACACTGGTAATCCCGATTATTTCTACGAGGCATGATAAAATAAAAGTATATTTCTTGATTTGTAG
AGCCCATCACGGCCGACCTC

Product: UMUC-like DNA-repair protein

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MHVDMNAFFASVEQQHDPALRGKPIAVIGSAARTVITTASYEARAFGVKTGMTVWQAQQKCPQIILVTGDNRKYTYTSAR
IVEMMKQFTPLVEVFSIDEAFLDVTGSLSLYSSAERIAFLLKAEIRHHFGLTCSIGIAPNKLLAKLASEMKKPDGLTVIK
PDDVAPVLETLPIKELCGIGAKMECQLNLLGIRTCGELGRYPVDRLMRKFGIVGEKLHLMGQGIDDSPVVPHEEAEEVKS
VGHSTTLEHDIEDRREILRWLLQLSEMVGRRARRYNVWGKTVTLSIRYADFDTWVGRQETLPHHINQSDDIYRAAVAILD
TLVLEQPVRLLGVRLSNLRYESNQLPLFEEERKKVLLAGAMDQVNDRFGDFAVTFGSLLDKERRQEKGSHVISPAWRPEG
IRNVDVK

Sequences:

>Translated_407_residues
MHVDMNAFFASVEQQHDPALRGKPIAVIGSAARTVITTASYEARAFGVKTGMTVWQAQQKCPQIILVTGDNRKYTYTSAR
IVEMMKQFTPLVEVFSIDEAFLDVTGSLSLYSSAERIAFLLKAEIRHHFGLTCSIGIAPNKLLAKLASEMKKPDGLTVIK
PDDVAPVLETLPIKELCGIGAKMECQLNLLGIRTCGELGRYPVDRLMRKFGIVGEKLHLMGQGIDDSPVVPHEEAEEVKS
VGHSTTLEHDIEDRREILRWLLQLSEMVGRRARRYNVWGKTVTLSIRYADFDTWVGRQETLPHHINQSDDIYRAAVAILD
TLVLEQPVRLLGVRLSNLRYESNQLPLFEEERKKVLLAGAMDQVNDRFGDFAVTFGSLLDKERRQEKGSHVISPAWRPEG
IRNVDVK
>Mature_407_residues
MHVDMNAFFASVEQQHDPALRGKPIAVIGSAARTVITTASYEARAFGVKTGMTVWQAQQKCPQIILVTGDNRKYTYTSAR
IVEMMKQFTPLVEVFSIDEAFLDVTGSLSLYSSAERIAFLLKAEIRHHFGLTCSIGIAPNKLLAKLASEMKKPDGLTVIK
PDDVAPVLETLPIKELCGIGAKMECQLNLLGIRTCGELGRYPVDRLMRKFGIVGEKLHLMGQGIDDSPVVPHEEAEEVKS
VGHSTTLEHDIEDRREILRWLLQLSEMVGRRARRYNVWGKTVTLSIRYADFDTWVGRQETLPHHINQSDDIYRAAVAILD
TLVLEQPVRLLGVRLSNLRYESNQLPLFEEERKKVLLAGAMDQVNDRFGDFAVTFGSLLDKERRQEKGSHVISPAWRPEG
IRNVDVK

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI7706681, Length=341, Percent_Identity=30.791788856305, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI84043967, Length=340, Percent_Identity=30.5882352941176, Blast_Score=145, Evalue=1e-34,
Organism=Homo sapiens, GI154350220, Length=350, Percent_Identity=30.5714285714286, Blast_Score=141, Evalue=1e-33,
Organism=Homo sapiens, GI7705344, Length=108, Percent_Identity=37.962962962963, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI5729982, Length=155, Percent_Identity=31.6129032258064, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1786425, Length=253, Percent_Identity=41.501976284585, Blast_Score=184, Evalue=7e-48,
Organism=Escherichia coli, GI1787432, Length=224, Percent_Identity=29.9107142857143, Blast_Score=95, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17537959, Length=238, Percent_Identity=29.8319327731092, Blast_Score=96, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI193205700, Length=131, Percent_Identity=38.1679389312977, Blast_Score=92, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI115534089, Length=156, Percent_Identity=35.8974358974359, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193205702, Length=241, Percent_Identity=33.195020746888, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI21355641, Length=311, Percent_Identity=29.5819935691318, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI24644984, Length=311, Percent_Identity=29.5819935691318, Blast_Score=125, Evalue=5e-29,
Organism=Drosophila melanogaster, GI19923006, Length=421, Percent_Identity=26.603325415677, Blast_Score=122, Evalue=5e-28,
Organism=Drosophila melanogaster, GI24668444, Length=159, Percent_Identity=31.4465408805031, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 45749; Mature: 45749

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHVDMNAFFASVEQQHDPALRGKPIAVIGSAARTVITTASYEARAFGVKTGMTVWQAQQK
CCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCHHEEEECCCCHHEEECCCCCHHHHHHHC
CPQIILVTGDNRKYTYTSARIVEMMKQFTPLVEVFSIDEAFLDVTGSLSLYSSAERIAFL
CCEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LKAEIRHHFGLTCSIGIAPNKLLAKLASEMKKPDGLTVIKPDDVAPVLETLPIKELCGIG
HHHHHHHHCCCEEEECCCCHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHCCHHHHHCCC
AKMECQLNLLGIRTCGELGRYPVDRLMRKFGIVGEKLHLMGQGIDDSPVVPHEEAEEVKS
CCEEEEEEEEEEHHHHHHCCCCHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCHHHHHHHH
VGHSTTLEHDIEDRREILRWLLQLSEMVGRRARRYNVWGKTVTLSIRYADFDTWVGRQET
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEEEEECCHHHCCCCCC
LPHHINQSDDIYRAAVAILDTLVLEQPVRLLGVRLSNLRYESNQLPLFEEERKKVLLAGA
CCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCEECCCCCCCCHHHHHHEEEHHH
MDQVNDRFGDFAVTFGSLLDKERRQEKGSHVISPAWRPEGIRNVDVK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCC
>Mature Secondary Structure
MHVDMNAFFASVEQQHDPALRGKPIAVIGSAARTVITTASYEARAFGVKTGMTVWQAQQK
CCCCHHHHHHHHHHHCCCCCCCCCEEEEECCCHHEEEECCCCHHEEECCCCCHHHHHHHC
CPQIILVTGDNRKYTYTSARIVEMMKQFTPLVEVFSIDEAFLDVTGSLSLYSSAERIAFL
CCEEEEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LKAEIRHHFGLTCSIGIAPNKLLAKLASEMKKPDGLTVIKPDDVAPVLETLPIKELCGIG
HHHHHHHHCCCEEEECCCCHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHCCHHHHHCCC
AKMECQLNLLGIRTCGELGRYPVDRLMRKFGIVGEKLHLMGQGIDDSPVVPHEEAEEVKS
CCEEEEEEEEEEHHHHHHCCCCHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCHHHHHHHH
VGHSTTLEHDIEDRREILRWLLQLSEMVGRRARRYNVWGKTVTLSIRYADFDTWVGRQET
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEEEEECCHHHCCCCCC
LPHHINQSDDIYRAAVAILDTLVLEQPVRLLGVRLSNLRYESNQLPLFEEERKKVLLAGA
CCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCEECCCCCCCCHHHHHHEEEHHH
MDQVNDRFGDFAVTFGSLLDKERRQEKGSHVISPAWRPEGIRNVDVK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA