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The map label for this gene is atoS [H]

Identifier: 78222608

GI number: 78222608

Start: 1563822

End: 1565465

Strand: Direct

Name: atoS [H]

Synonym: Gmet_1396

Alternate gene names: 78222608

Gene position: 1563822-1565465 (Clockwise)

Preceding gene: 78222607

Following gene: 78222609

Centisome position: 39.12

GC content: 56.87

Gene sequence:

>1644_bases
ATGTACAGAGAACGGCTCGTATGGTTCATCCTTGCCCGGGTGGTGGTGGTTTCCCTCTTTCTTTTCTCCACCATTGTCCT
GCGCGCGCGGGGGACCGGCACCCTCGGCGAACAGGCCCTTGACGGCATAACCGCCATCCTGGTTGCCACCTACGGCTTCT
CCATCCTGTTGCTCCTGATTCTCAAGCTGGCAAAGGGATACCAGCTACCCCTCACCTATGCGCAGATCATCTGGGACATC
CTTTTCGTCACGGGGCTTATTCTCTATACGGGAGGAATTTCCAGCCCCTTCTCGTTTCTCTATCTGCTGGCGATCATCAG
TGCCAGCGTCCTTCTGGCGCGTCGGGAGGCCTTTTATACGGCATCGCTCTGCTCCATCGTCTACGGCGGGATCATCGATC
TGCAGTATTACGGGCAACTGGTATCCATTGGGCTGGGCCCCCTCGTGGCCCAGCGATATGGCACCAACTATATCTTCTAT
ACGATCTTCATCAATATTGTAGCCTTCTTCCTGACCGCGCTCCTGACAGGGTATCTGGCCGAGCGGGCCAGGGAAAGCGA
GACGGAACTTGAAAAACGGGCCATTGATTACGAGGAACTGGAACGCCTCAACAGCTCCATAGTCTCCAACCTCACCAGTG
GCCTTCTGACCGTTACCGCCGAGGGGCGCATCCGGGTCTTCAACCACTACGCCGAGACCTTTACCGGCATCACTCAGGAG
GATGCCTACGACCGGGACCTCTATGACATCTTTCCGGGATTCCGCCTCTACGAGGGGAACCTCTCCAATGTTAAGCGGGG
AGTCTTCGAATTGCTGGCGAAAAACGGCCGCAAGCTCATTGTCGGGTTCAATAGCGTGCCCCTTACCGGCAAGGAGGGGG
AGAGCGCGGGGACGCTCATCAATTTCCAGAACCTGACCCAGATAAAACGGATGGAGGAGAATCTCAAGCGGGCCGACCGT
CTTGCTGTCATCGGGGAACTCTCGGCCCGCATGGCCCATGAGATCCGAAATCCTTTGGCAGCCATCAGCGGATCGGCTCA
ACTCATCGCCCAGGGAGACGGGATTCCCGAGGCCGACCGTGAACTCTTTGCCATTGTCCTGCGGGAAGCTGACCGGCTTA
ATGGCCTCATAACCGATTTTCTCGCCTATGCCCGACCCAGCCAGCCGGAGAAGGGACCGGTCAACCTGACCGATCTTGTT
GGAGAGATCGTATCCCTTGTGACACCGGACCGGCGTTTCGAACAAGTCAGGATTATCAACCGTGTGGAACCGGATTTTAC
CCTTCCGATTGATCCGGACCAGTTTCGGCAGGTCTTCTGGAACCTGTTCGTGAATGCGGCCGAGGCGATGAGCGAGGGGG
GGACGATCACTGTTGATGCGGAACGGATCGACGAGATCCGCTCTGATGGCGAACCGCGGAGCGCTTACCGGATAACCGTT
GCCGATGACGGTTCCGGCATGAACCAGGAAACCATTTCCAGGATTTTCGAGCCGTTTTACACCAGCAAGGCGAGCGGAAC
CGGCCTTGGCCTTGCCACCGTTTACCGCATCATCGAAGCCCACGGCGGCAGGATTACCGTGGAAAGCGCGGAAGGAACCG
GAACCATATTCATCATATTTATTCCCGTCCAGAGAAATTACTGA

Upstream 100 bases:

>100_bases
GCTCATGGTGTTCCTCGGCACCACCGTGGGGGGCCTTGTCATCGCCATGTACCTGCCGATTTTCAAGCTGGCCGGAACCG
TCGGCGGTTAGCCGGAGCCG

Downstream 100 bases:

>100_bases
GCAGCAAAGACTCGTTCAATAGCCCATCTAACCGTCAGGGAGAGACGTCATGGAAATACGAATACTGGTTGTCGATGACG
AGTTGAGCATGCGGGAATTC

Product: signal transduction histidine kinase, nitrogen specific, NtrB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 547; Mature: 547

Protein sequence:

>547_residues
MYRERLVWFILARVVVVSLFLFSTIVLRARGTGTLGEQALDGITAILVATYGFSILLLLILKLAKGYQLPLTYAQIIWDI
LFVTGLILYTGGISSPFSFLYLLAIISASVLLARREAFYTASLCSIVYGGIIDLQYYGQLVSIGLGPLVAQRYGTNYIFY
TIFINIVAFFLTALLTGYLAERARESETELEKRAIDYEELERLNSSIVSNLTSGLLTVTAEGRIRVFNHYAETFTGITQE
DAYDRDLYDIFPGFRLYEGNLSNVKRGVFELLAKNGRKLIVGFNSVPLTGKEGESAGTLINFQNLTQIKRMEENLKRADR
LAVIGELSARMAHEIRNPLAAISGSAQLIAQGDGIPEADRELFAIVLREADRLNGLITDFLAYARPSQPEKGPVNLTDLV
GEIVSLVTPDRRFEQVRIINRVEPDFTLPIDPDQFRQVFWNLFVNAAEAMSEGGTITVDAERIDEIRSDGEPRSAYRITV
ADDGSGMNQETISRIFEPFYTSKASGTGLGLATVYRIIEAHGGRITVESAEGTGTIFIIFIPVQRNY

Sequences:

>Translated_547_residues
MYRERLVWFILARVVVVSLFLFSTIVLRARGTGTLGEQALDGITAILVATYGFSILLLLILKLAKGYQLPLTYAQIIWDI
LFVTGLILYTGGISSPFSFLYLLAIISASVLLARREAFYTASLCSIVYGGIIDLQYYGQLVSIGLGPLVAQRYGTNYIFY
TIFINIVAFFLTALLTGYLAERARESETELEKRAIDYEELERLNSSIVSNLTSGLLTVTAEGRIRVFNHYAETFTGITQE
DAYDRDLYDIFPGFRLYEGNLSNVKRGVFELLAKNGRKLIVGFNSVPLTGKEGESAGTLINFQNLTQIKRMEENLKRADR
LAVIGELSARMAHEIRNPLAAISGSAQLIAQGDGIPEADRELFAIVLREADRLNGLITDFLAYARPSQPEKGPVNLTDLV
GEIVSLVTPDRRFEQVRIINRVEPDFTLPIDPDQFRQVFWNLFVNAAEAMSEGGTITVDAERIDEIRSDGEPRSAYRITV
ADDGSGMNQETISRIFEPFYTSKASGTGLGLATVYRIIEAHGGRITVESAEGTGTIFIIFIPVQRNY
>Mature_547_residues
MYRERLVWFILARVVVVSLFLFSTIVLRARGTGTLGEQALDGITAILVATYGFSILLLLILKLAKGYQLPLTYAQIIWDI
LFVTGLILYTGGISSPFSFLYLLAIISASVLLARREAFYTASLCSIVYGGIIDLQYYGQLVSIGLGPLVAQRYGTNYIFY
TIFINIVAFFLTALLTGYLAERARESETELEKRAIDYEELERLNSSIVSNLTSGLLTVTAEGRIRVFNHYAETFTGITQE
DAYDRDLYDIFPGFRLYEGNLSNVKRGVFELLAKNGRKLIVGFNSVPLTGKEGESAGTLINFQNLTQIKRMEENLKRADR
LAVIGELSARMAHEIRNPLAAISGSAQLIAQGDGIPEADRELFAIVLREADRLNGLITDFLAYARPSQPEKGPVNLTDLV
GEIVSLVTPDRRFEQVRIINRVEPDFTLPIDPDQFRQVFWNLFVNAAEAMSEGGTITVDAERIDEIRSDGEPRSAYRITV
ADDGSGMNQETISRIFEPFYTSKASGTGLGLATVYRIIEAHGGRITVESAEGTGTIFIIFIPVQRNY

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=352, Percent_Identity=31.25, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI1790436, Length=236, Percent_Identity=36.0169491525424, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI1790300, Length=245, Percent_Identity=31.4285714285714, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI48994928, Length=282, Percent_Identity=28.0141843971631, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI145693157, Length=372, Percent_Identity=26.0752688172043, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI87081816, Length=228, Percent_Identity=29.3859649122807, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786600, Length=355, Percent_Identity=26.4788732394366, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788713, Length=272, Percent_Identity=27.2058823529412, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1788393, Length=300, Percent_Identity=26.3333333333333, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786783, Length=249, Percent_Identity=28.9156626506024, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1789149, Length=256, Percent_Identity=28.125, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1790861, Length=219, Percent_Identity=28.7671232876712, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789808, Length=225, Percent_Identity=28, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1790346, Length=258, Percent_Identity=27.906976744186, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 60775; Mature: 60775

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRERLVWFILARVVVVSLFLFSTIVLRARGTGTLGEQALDGITAILVATYGFSILLLLI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LKLAKGYQLPLTYAQIIWDILFVTGLILYTGGISSPFSFLYLLAIISASVLLARREAFYT
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ASLCSIVYGGIIDLQYYGQLVSIGLGPLVAQRYGTNYIFYTIFINIVAFFLTALLTGYLA
HHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
ERARESETELEKRAIDYEELERLNSSIVSNLTSGLLTVTAEGRIRVFNHYAETFTGITQE
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCEEEEEECCCEEHHHHHHHHHCCCCCC
DAYDRDLYDIFPGFRLYEGNLSNVKRGVFELLAKNGRKLIVGFNSVPLTGKEGESAGTLI
CCCCCCHHHHCCCCEEECCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCEE
NFQNLTQIKRMEENLKRADRLAVIGELSARMAHEIRNPLAAISGSAQLIAQGDGIPEADR
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCEEEECCCCCCHHHH
ELFAIVLREADRLNGLITDFLAYARPSQPEKGPVNLTDLVGEIVSLVTPDRRFEQVRIIN
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHH
RVEPDFTLPIDPDQFRQVFWNLFVNAAEAMSEGGTITVDAERIDEIRSDGEPRSAYRITV
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCCCEEEEEE
ADDGSGMNQETISRIFEPFYTSKASGTGLGLATVYRIIEAHGGRITVESAEGTGTIFIIF
ECCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCEEEEEE
IPVQRNY
EECCCCC
>Mature Secondary Structure
MYRERLVWFILARVVVVSLFLFSTIVLRARGTGTLGEQALDGITAILVATYGFSILLLLI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LKLAKGYQLPLTYAQIIWDILFVTGLILYTGGISSPFSFLYLLAIISASVLLARREAFYT
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
ASLCSIVYGGIIDLQYYGQLVSIGLGPLVAQRYGTNYIFYTIFINIVAFFLTALLTGYLA
HHHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
ERARESETELEKRAIDYEELERLNSSIVSNLTSGLLTVTAEGRIRVFNHYAETFTGITQE
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCEEEEEECCCEEHHHHHHHHHCCCCCC
DAYDRDLYDIFPGFRLYEGNLSNVKRGVFELLAKNGRKLIVGFNSVPLTGKEGESAGTLI
CCCCCCHHHHCCCCEEECCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCEE
NFQNLTQIKRMEENLKRADRLAVIGELSARMAHEIRNPLAAISGSAQLIAQGDGIPEADR
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCEEEECCCCCCHHHH
ELFAIVLREADRLNGLITDFLAYARPSQPEKGPVNLTDLVGEIVSLVTPDRRFEQVRIIN
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHH
RVEPDFTLPIDPDQFRQVFWNLFVNAAEAMSEGGTITVDAERIDEIRSDGEPRSAYRITV
HCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHCCCCCCCEEEEEE
ADDGSGMNQETISRIFEPFYTSKASGTGLGLATVYRIIEAHGGRITVESAEGTGTIFIIF
ECCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCEEEEEE
IPVQRNY
EECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]